Halogen Containing Patents (Class 436/101)
-
Patent number: 11319331Abstract: The present disclosure shows a molecular probe SF-1 which is useful for selective detection of hypochlorous acid (HOCl) over other reactive oxygen species (ROS) and a process for the preparation thereof.Type: GrantFiled: May 8, 2018Date of Patent: May 3, 2022Assignee: Council of Scientific & Industrial ResearchInventors: Firoj Ali, Sunil Babanrao Aute, Anila Hoskere Ashok, Suman Pal, Amitava Das
-
Patent number: 10883973Abstract: A gas detection fuse is provided, comprising a thin strip or sheet of a conductive material, such as a metal, connecting two electrodes for detecting a gas of interest. The metal is selected to be reactive with the gas of interest, and has a relatively large surface area, such that when the gas of interest contacts the metal, the electrical connection between the electrodes is broken (e.g., due to the metal losing physical integrity, or becoming non-conductive, as a result of the reaction with the gas). The gas of interest may be chlorine, and the conducting material may be tin. When the tin is exposed to chlorine the tin becomes oxidized to produce liquid tin tetrachloride, thus breaking the electrical connection.Type: GrantFiled: March 4, 2015Date of Patent: January 5, 2021Assignee: BL TECHNOLOGIES, INC.Inventor: Jesse Colin Manley
-
Patent number: 10845356Abstract: Systems and methods are provided for estimating the total base number of used oil in an engine. The systems and methods can involve characterizing the sulfur content and at least one other element content of the oil both before introduction into the engine and after passing through an engine cylinder during combustion. Depending on the aspect, a total base number of the oil prior to use can also be measured, or the total base number before use can be estimated based on the at least one element content.Type: GrantFiled: December 6, 2018Date of Patent: November 24, 2020Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANYInventors: Gary Christensen, Nabila Brabez, Willie A. Givens, Jr., Kevin L. Crouthamel, Andrew D. Satterfield
-
Patent number: 10604690Abstract: A composition including the compound HFO-1234yf and at least one other, additional, compound selected from HCFC-240db, HCFO-1233xf, HCFC-243db, HCFO-1233zd, HCC-40, HCFC-114a, HCFC-115, HCFC-122, HCFC-23, HCFC-124, HCFC-124a, HFC-125, HCFC-133a, HCFC-142, HCFC-143, HFC-52a, HCFC-243ab, HCFC-244eb, HFC-281ea, HCO-1110, HCFO-1111, HCFO-1113, HCFO-1223xd, and HCFO-1224xe. A composition including the compound HFO-1234yf and at least two compounds selected from HFO-1234ze, HFC-245cb, HFC-134a, HCFC-115, HFC-152a, HCC-40 and HFO-1243zf.Type: GrantFiled: April 7, 2017Date of Patent: March 31, 2020Assignee: ARKEMA FRANCEInventors: Bertrand Collier, Dominique Deur-Bert, Laurent Wendlinger
-
Patent number: 10054570Abstract: Methods and kits for detection of alkylating agents are described. The present invention discloses methods and kits comprising sensors for the rapid detection of chemical agents (e.g., alkylating agents) at low concentrations. The methods are useful for the detection of alkylating agents such as field fumigants such as methyl bromide or methyl iodide. The detection can advantageously be performed by a change in light absorbance of the sensor moiety using the naked eye.Type: GrantFiled: November 19, 2015Date of Patent: August 21, 2018Assignee: The Regents of the University of CaliforniaInventors: Gang Sun, Sanaz Ghanbari
-
Patent number: 9857304Abstract: A measuring method of bromate ion concentration includes a first fluorescence intensity measuring process including a process of passing hydrochloric acid through an anion exchanger to elute bromate ions adsorbed to the anion exchanger into the hydrochloric acid and a process of measuring the fluorescence intensity of the hydrochloric acid passed through the anion exchanger, a second fluorescence intensity measuring process including a process of passing a hydrochloric acid solution containing a fluorescent substance whose fluorescence intensity changes due to coexistence of bromate ions through an anion exchanger to elute bromate ions adsorbed to the anion exchanger into the hydrochloric acid solution and a process of measuring the fluorescence intensity of the hydrochloric acid solution passed through the anion exchanger, and a calculation process determining the bromate ion concentration in the water sample by using the difference between the fluorescence intensities of the hydrochloric acid solution and tType: GrantFiled: January 30, 2017Date of Patent: January 2, 2018Assignee: Metawater Co., Ltd.Inventors: Natsumi Konishi, Eri Hasegawa
-
Patent number: 9533354Abstract: A method for preparing hydrophobic gold nanoparticles includes adding 1,2-dichlorobenzene as a solvent to gold precursor and using oleylamine and oleic acid with volume ratio of 7.5:2.5 to 5:5 as surfactants. The size of the prepared gold nanoparticles can be controlled over a broad range and may be utilized in various fields such as bio-imaging, photonic crystallization, sensors, organic catalysts, surface enhanced raman spectrum, electronic devices, etc. Further, a method for colorimetric detection of a strong acid uses hydrophilic nanoparticles that are phase transited from the prepared hydrophobic gold nanoparticles. Up to 5 ppm of low content hydrochloric acid can be detected utilizing phase transited hydrophilic nanoparticles in the colorimetric detection method, and the gold nanoparticles that were used in the detection of strong acid can be reused without loss of activity through neutralization with bases.Type: GrantFiled: November 22, 2013Date of Patent: January 3, 2017Assignee: Korea Basic Science InstituteInventors: Gae Hang Lee, Doo Ri Bae, Yeon Suk Choi
-
Patent number: 9007593Abstract: Methods and systems of the invention can determine the identity and quantity of analytes in a vapor. In preferred methods, a porous optical film is exposed to vapor which contains analyte. The porous optical film is heated and its optical response is monitored during heating. An optical response observed via heating can determine the identity and/or quantity of the analyte. In preferred embodiments, optical response during a thermal pulse is compared to a database of sensor responses that are characteristic of various analytes. Preferred methods are conducted a relatively low temperatures, for example below about 200° C. In preferred methods, a heating and cooling cycle produces a hysteresis curve in the optical response that is indicative of analytes. In preferred embodiments, a thermal reset pulse resets the porous optical film for later use and also provides an optical response that can be used for sensing.Type: GrantFiled: July 19, 2011Date of Patent: April 14, 2015Assignee: The Regents of the University of CaliforniaInventors: Michael J. Sailor, Brian H King, Sadafumi Noda
-
Patent number: 8889421Abstract: The present invention relates generally to a kit and method for the colorimetric detection of precursors used in the assembly of homemade explosives (HMEs). More specifically, the present invention relates to a bulk HME precursor detection kit and methods of using a kit that is capable of bulk detection of HME precursors, such as urea nitrate, ammonium nitrate and potassium chlorate.Type: GrantFiled: August 24, 2011Date of Patent: November 18, 2014Assignee: The United States of America as Represented by the Secretary of the NavyInventors: Wayne Ouellette, John H. Wilkinson, James N. Thomasson, III, Frederick S. Heim, Herbert Mitchell, Robert G. Best
-
Publication number: 20140315320Abstract: The invention is directed towards methods and compositions for identifying the amount of hydrofluoric acid in a buffered oxide etching composition. In buffered oxide etching compositions it is very difficult to measure the amount of hydrofluoric acid because it has varying equilibriums and it is toxic so it hard to handle and sample. When used to manufacture microchips however, incorrect amounts of hydrofluoric acid will ruin those chips. The invention utilizes a unique method of spectrographically measuring the hydrofluoric acid when in contact with added chromogenic agents to obtain exact measurements that are accurate, immediate, and safe.Type: ApplicationFiled: July 2, 2014Publication date: October 23, 2014Applicant: NALCO COMPANYInventors: Amy M. Tseng, Brian V. Jenkins, Robert M. Mack
-
Patent number: 8828733Abstract: The compositions and methods relate to an organic polymer-inorganic particle sensor material for detecting analytes. Interactions between the polymer and the particles are affected by the presence of analyte, which displaces the polymer and increases its free volume. This change in free volume can be detected, e.g., using an embedded piezoresistive microcantilever (EPM) sensor. Analytes that can be detected include noxious substances, such as hydrogen cyanide gas and carbon monoxide.Type: GrantFiled: January 18, 2008Date of Patent: September 9, 2014Assignees: Cantimer, Inc., Arizona Board Of Regents For And On Behalf Of Northern Arizona UniversityInventors: Timothy L. Porter, Ray Stewart, Timothy L. Vail
-
Publication number: 20140248706Abstract: The present invention provides a stabilized refrigerant composition containing a hydrofluoropropene with low global warming potential (GWP) that can remain stable even in the presence of air (oxygen) for a long period of time. More specifically, the present invention provides a refrigerant composition containing a hydrofluoropropene and a stabilizer. The stabilizer is at least one member selected from the group consisting of alkylcatechols, alkoxyphenols, benzoquinones, phenothiazines, and phthalates.Type: ApplicationFiled: May 14, 2014Publication date: September 4, 2014Applicant: DAIKIN INDUSTRIES, LTD.Inventors: Tatsumi TSUCHIYA, Takashi SHIBANUMA, Yasufu YAMADA, Hitomi ARIMOTO
-
Publication number: 20140199773Abstract: A detection method using colorimetric analysis of the present invention includes: providing a first solution in which two materials selected from metal nanoparticles, an oxidizing agent, and chloride ions are mixed; providing a second solution including one other material that is not included in the first solution among the metal nanoparticles, the oxidizing agent, and the chloride ions; preparing a mixture solution by mixing the first solution and the second solution; and testing and measuring a color change of the mixture solution.Type: ApplicationFiled: April 2, 2012Publication date: July 17, 2014Applicant: KOREA INSTITUTE OF MACHINERY & MATERIALSInventors: ChangSoo Han, Duck Jong Kim, Tripathy Suraj Kumar
-
Patent number: 8778691Abstract: A method for measuring bromate ion is provided that provides high-sensitivity measurement results more simply and more quickly than conventional bromate ion measurement methods. A fluorescent substance that is quenched by coexistence with bromate ions is added to a sample 130 and the fluorescence intensity of the fluorescent substance after quenching is measured, the measured fluorescence intensity being subtracted from the fluorescence intensity of a standard sample containing no bromate ions to calculated the fluorescence intensity difference. The bromate ion concentration is calculated from the calculated fluorescence intensity difference, using a pre-determined calibration line between the fluorescence intensity difference and the bromate ion concentration.Type: GrantFiled: September 7, 2012Date of Patent: July 15, 2014Assignees: Meta Water Co., Ltd., Ibaraki UniversityInventors: Shukuro Igarashi, Jun Kato, Yoshiharu Tanaka
-
Patent number: 8778690Abstract: The invention provides a porous sensor and sensing methods that use a porous sensor with a porous nanostructure having an optical response and having a portion of the porous nanostructure filled with a fiducial marker that is non-reactive to an analyte of interest. In a preferred sensing method, reflectance spectra from both the fiducial marker and reactive portions of the porous structure are acquired simultaneously. The fiducial marker provides an internal reference that permits compensation for humidity, as well as off angle measurements. In addition, simple visual observations can reveal the presence of an analyte, including human observations.Type: GrantFiled: August 31, 2011Date of Patent: July 15, 2014Assignee: The Regents of the University of CaliforniaInventors: Michael J. Sailor, Anne M. Ruminski
-
Patent number: 8753896Abstract: A method of monitoring a surfactant in a microelectronic process is disclosed. Specifically, the monitoring of a surfactant occurs by studying the fluorescence or electromagnetic emission of a sample collected from a microelectronic process.Type: GrantFiled: April 5, 2007Date of Patent: June 17, 2014Assignee: Nalco CompanyInventors: Brian V. Jenkins, John E. Hoots, Amy M. Tseng
-
Publication number: 20140154811Abstract: Technologies are generally described for gas filtration and detection devices. Example devices may include a graphene membrane and a sensing device. The graphene membrane may be perforated with a plurality of discrete pores having a size-selective to enable one or more molecules to pass through the pores. A sensing device may be attached to a supporting permeable substrate and coupled with the graphene membrane. A fluid mixture including two or more molecules may be exposed to the graphene membrane. Molecules having a smaller diameter than the discrete pores may be directed through the graphene pores, and may be detected by the sensing device. Molecules having a larger size than the discrete pores may be prevented from crossing the graphene membrane. The sensing device may be configured to identify a presence of a selected molecule within the mixture without interference from contaminating factors.Type: ApplicationFiled: November 30, 2012Publication date: June 5, 2014Inventors: Angele Sjong, Kraig Anderson, Gary L. Duerksen, Seth Adrian Miller
-
Publication number: 20140073060Abstract: The invention is directed towards methods and compositions for identifying the amount of hydrofluoric acid in a buffered oxide etching composition. In buffered oxide etching compositions it is very difficult to measure the amount of hydrofluoric acid because it has varying equilibriums and it is toxic so it hard to handle and sample. When used to manufacture microchips however, incorrect amounts of hydrofluoric acid will ruin those chips. The invention utilizes a unique method of spectrographically measuring the hydrofluoric acid when in contact with added chromogenic agents to obtain exact measurements that are accurate, immediate, and safe.Type: ApplicationFiled: November 18, 2013Publication date: March 13, 2014Applicant: Nalco CompanyInventors: Amy M. Tseng, Brian V. Jenkins, Robert Mack
-
Patent number: 8642350Abstract: A sensor material of the type comprising a long-decay photoluminescent, protonable dye embedded in a suitable polymeric matrix, is used for generating a specific optical response to two different analytes present in a sample, thus allowing selective determination of the two analytes in the sample. Also described is a method for the simultaneous sensing of a first and second analyte in a sample. The method comprises the steps of irradiating a sensor material of the type comprising a long-decay photoluminescent protonable dye embedded in a suitable polymeric matrix with light of one or two wavelengths, determining photoluminescence intensity and lifetime signals originating from the sensor, and correlating the photoluminescence intensity signal with a concentration of the first analyte and the photoluminescence lifetime signal(s) with the concentration of the second analyte.Type: GrantFiled: March 29, 2011Date of Patent: February 4, 2014Assignee: University College Cork, National University of Ireland, CorkInventor: Dmitri Papkovsky
-
Patent number: 8614096Abstract: Method of determining a total HF concentration metric in an environment including measuring an uncorrected HF concentration metric in the environment based on a first infrared absorption measurement at a wavelength corresponding to a vibrational frequency of a non-hydrogen bonded gas phase HF molecule; determining an ambient H2O concentration metric in the environment available for reaction with the non-hydrogen bonded gas phase HF molecules at or about the time of obtaining the first infrared absorption measurement; calculating a HF hydrate concentration metric in the environment based on the uncorrected HF concentration metric, the ambient H2O concentration metric and a reaction equilibrium relationship between the non-hydrogen bonded gas phase HF molecule and the HF hydrate; and determining the total HF concentration metric in the environment based on the uncorrected HF concentration metric and an amount of HF determined by the HF hydrate concentration metric.Type: GrantFiled: September 1, 2011Date of Patent: December 24, 2013Assignee: ExxonMobil Research and Engineering CompanyInventors: Manuel S. Alvarez, David B. Spry
-
Publication number: 20130280749Abstract: A FRET donor-acceptor pair for use as a biosensor, comprising at least two fluorescence proteins, wherein at least one fluorescence protein is stable with respect to a parameter to be detected by the biosensor and at least one fluorescence protein is unstable with respect to the parameter to be detected by the biosensor.Type: ApplicationFiled: August 16, 2011Publication date: October 24, 2013Applicant: EVOCATAL GMBHInventors: Karl Erich Jaeger, Thomas Drepper, Stephan Endres, Janko Potzkei, Achim Heck, Franco Circolone
-
Publication number: 20130183773Abstract: The invention is directed towards methods and compositions for identifying the amount of hydrofluoric acid in a buffered oxide etching composition. In buffered oxide etching compositions it is very difficult to measure the amount of hydrofluoric acid because it has varying equilibriums and it is toxic so it hard to handle and sample. When used to manufacture microchips however, incorrect amounts of hydrofluoric acid will ruin those chips. The invention utilizes a unique method of spectrographically measuring the hydrofluoric acid when in contact with added chromogenic agents to obtain exact measurements that are accurate, immediate, and safe.Type: ApplicationFiled: December 31, 2012Publication date: July 18, 2013Inventors: Amy M. Tseng, Brian V. Jenkins, Robert Mack
-
Patent number: 8435796Abstract: A method for using of a fabric comprising a material chosen from metals, metallic alloys, polymers, inorganic compounds and mixtures thereof, which material is capable of detecting the presence of a chemical substance, for the detection of said chemical substance.Type: GrantFiled: November 16, 2010Date of Patent: May 7, 2013Assignee: Commissariat a l'Energie Atomique et aux Energies AlternativesInventors: Jean Brun, Catherine Durand, Alain Soubie
-
Publication number: 20130059395Abstract: Method of determining a total HF concentration metric in an environment including measuring an uncorrected HF concentration metric in the environment based on a first infrared absorption measurement at a wavelength corresponding to a vibrational frequency of a non-hydrogen bonded gas phase HF molecule; determining an ambient H2O concentration metric in the environment available for reaction with the non-hydrogen bonded gas phase HF molecules at or about the time of obtaining the first infrared absorption measurement; calculating a HF hydrate concentration metric in the environment based on the uncorrected HF concentration metric, the ambient H2O concentration metric and a reaction equilibrium relationship between the non-hydrogen bonded gas phase HF molecule and the HF hydrate; and determining the total HF concentration metric in the environment based on the uncorrected HF concentration metric and an amount of HF determined by the HF hydrate concentration metric.Type: ApplicationFiled: September 1, 2011Publication date: March 7, 2013Applicant: ExxonMobil Research and Engineering CompanyInventors: Manuel S. ALVAREZ, David B. SPRY
-
Patent number: 8377704Abstract: Provided herein are methods of detecting anions in solution. In particular, the methods can be used to detect trace anions in solution. For example, the anions can be present in an amount of between about 500 femtomoles to about 10 millimoles.Type: GrantFiled: October 19, 2010Date of Patent: February 19, 2013Assignee: NUtech VenturesInventors: Stephen DiMagno, Ronald Cerny
-
Publication number: 20120329165Abstract: A method for measuring bromate ion is provided that provides high-sensitivity measurement results more simply and more quickly than conventional bromate ion measurement methods. A fluorescent substance that is quenched by coexistence with bromate ions is added to a sample 130 and the fluorescence intensity of the fluorescent substance after quenching is measured, the measured fluorescence intensity being subtracted from the fluorescence intensity of a standard sample containing no bromate ions to calculated the fluorescence intensity difference. The bromate ion concentration is calculated from the calculated fluorescence intensity difference, using a pre-determined calibration line between the fluorescence intensity difference and the bromate ion concentration.Type: ApplicationFiled: September 7, 2012Publication date: December 27, 2012Inventors: Shukuro Igarashi, Jun Kato, Yoshiharu Tanaka
-
Patent number: 8143069Abstract: A compound represented by the following general formula (II): wherein R21 represents hydrogen atom or one to four monovalent substituents substituting on the benzene ring, and when R21 represents two or more substituents, the substituents may be the same or different; R22, R24, R25, and R27 independently represent hydrogen atom, or a monovalent substituent; R23 represents —OH or —N(R28)(R29) (wherein R28 and R29 independently represent an alkyl group which may be substituted); R26 represents —N(R30)(R31) (wherein R30 and R31 independently represent an alkyl group which may be substituted); n represents an integer of 1 to 3; and Y represents —S— or —O—, which is useful for selective measurement of hypochlorite ion.Type: GrantFiled: March 1, 2007Date of Patent: March 27, 2012Assignee: The University of TokyoInventors: Tetsuo Nagano, Yasuteru Urano, Suguru Kenmoku
-
Publication number: 20120058567Abstract: The invention provides a porous sensor and sensing methods that use a porous sensor with a porous nanostructure having an optical response and having a portion of the porous nanostructure filled with a fiducial marker that is non-reactive to an analyte of interest. In a preferred sensing method, reflectance spectra from both the fiducial marker and reactive portions of the porous structure are acquired simultaneously. The fiducial marker provides an internal reference that permits compensation for humidity, as well as off angle measurements. In addition, simple visual observations can reveal the presence of an analyte, including human observations.Type: ApplicationFiled: August 31, 2011Publication date: March 8, 2012Applicant: The Regents of the University of CaliforniaInventors: Michael J. Sailor, Anne M. Ruminski
-
Publication number: 20110312101Abstract: The present invention provides a stabilized refrigerant composition containing a hydrofluoropropene with low global warming potential (GWP) that can remain stable even in the presence of air (oxygen) for a long period of time. More specifically, the present invention provides a refrigerant composition containing a hydrofluoropropene and a stabilizer. The stabilizer is at least one member selected from the group consisting of alkylcatechols, alkoxyphenols, benzoquinones, phenothiazines, and phthalates.Type: ApplicationFiled: February 26, 2010Publication date: December 22, 2011Applicant: DAIKIN INDUSTRIES, LTD.Inventors: Tatsumi Tsuchiya, Takashi Shibanuma, Yasufu Yamada, Hitomi Arimoto
-
Patent number: 7989211Abstract: This invention relates to the development of a new Raman enhancing reagent and a surface-enhanced Raman scattering (SERS) method for rapid and ultra-sensitive detection and identification of perchlorate (ClO4?) and other anions such as technetium (TcO4?), uranium and nitrate in environmental samples. The method involves the synthesis of controlled gold nanoparticles which are modified with amine functional groups such as 2-(dimethylamino)ethanethiol and N,N,N-trimethylaminethiol. These functionalized Au nanoparticles were found to be reactive with perchlorate and other anions and can be used to detect these anions by Raman spectroscopy at ultra low concentrations in complex environmental matrices. This invention overcomes the limitations of currently-available analytical techniques by offering an inexpensive, rapid, ultra-sensitive, and real-time identification and detection of perchlorate and other anions.Type: GrantFiled: December 22, 2009Date of Patent: August 2, 2011Assignee: UT-Battelle, LLCInventors: Baohua Gu, Chuanmin Ruan, Wei Wang
-
Publication number: 20110143442Abstract: The invention pertains to a method for determining the presence or absence of at least one chemical substance in a liquid medium, comprising a contacting step of said liquid medium with a device comprising at least one substrate coated, in whole or in part on at least one of its sides, with at least one layer comprising material able to be degraded fully or partly by said chemical substance, said material being chosen from among metals, metal alloys, metal oxides.Type: ApplicationFiled: May 26, 2009Publication date: June 16, 2011Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Soubie Alain, Jean Brun, Catherine Durand
-
Publication number: 20110117663Abstract: A method for using of a fabric comprising a material chosen from metals, metallic alloys, polymers, inorganic compounds and mixtures thereof, which material is capable of detecting the presence of a chemical substance, for the detection of said chemical substance.Type: ApplicationFiled: November 16, 2010Publication date: May 19, 2011Inventors: Jean BRUN, Catherine Durand, Alain Soubie
-
Publication number: 20100203579Abstract: A method for measuring the homeostatic relationship between various substances in the body. The measured levels of substances in the body use the interrelationships of the various substances in order to establish guidelines for treating individuals.Type: ApplicationFiled: February 5, 2010Publication date: August 12, 2010Inventor: WILLIAM J. McFAUL
-
Patent number: 7592184Abstract: There is disclosed an apparatus and method for detecting and measuring volatile acidic or basic components including ammonia, ammonium, or volatile amines (compound) in a gas or liquid state fluid. Specifically, the present invention provides a PTFE-carrier solid phase indicator film having an ammonia-sensitive indicator dye embedded therein, such that the dye moiety changes color or spectral properties upon exposure to the compound to be detected.Type: GrantFiled: May 28, 2002Date of Patent: September 22, 2009Assignee: Photonic BioSystems, Inc.Inventors: Gamal E. Khalil, David L. Putnam, Todd W. Hubbard
-
Patent number: 7390668Abstract: New intracorporeal photodynamic medicaments and certain medical uses and methods for use of such photodynamic medicaments for treatment of disease in human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthene or halogenated xanthene derivative. In preferred embodiments, such medicaments are used for treatment of a variety of conditions affecting the skin and related organs, the mouth and digestive tract and related organs, the urinary and reproductive tracts and related organs, the respiratory tract and related organs, the circulatory system and related organs, the head and neck, the endocrine and lymphoreticular systems and related organs, various other tissues, such as connective tissues and various tissue surfaces exposed during surgery, as well as various tissues exhibiting microbial or parasitic infection.Type: GrantFiled: March 6, 2001Date of Patent: June 24, 2008Assignee: Provectus Pharmatech, Inc.Inventors: H. Craig Dees, Timothy C. Scott, Eric A. Wachter, Walter G. Fisher, John Smolik
-
Patent number: 7374940Abstract: A substance in a condensed state, for example a powdered solid, is in continuous movement in the longitudinal direction (6) of a furnace (4, 5). A reactive gas mixture is brought into contact with the substance in the condensed state. A plurality of samples of the gaseous mixture are removed at a plurality of reference points (14) spaced apart from one another along the longitudinal direction (6) of the furnace (4, 5); each of the gas samples is analyzed outside the furnace to determine the composition of the gas mixture and for each point (14), the extent of a chemical reaction between the condensed substance and the reactive gas mixture is deduced from the composition of the gas mixture at each of the reference points (14). In particular, the apparatus comprises a sampling and injection rod (10) introduced into the furnace (4, 5) and disposed in its longitudinal direction (6).Type: GrantFiled: February 9, 2001Date of Patent: May 20, 2008Assignee: Societe Franco-Belge de Fabrication de Combustible-FBFCInventor: André Feugier
-
Patent number: 7273588Abstract: Methods for determining the amount of at least one metal analyte present in a liquid or gas sample of a halosilane supply (e.g., a chlorosilane supply) are disclosed herein. A sample of a halosilane supply is contacted and reacted with an aqueous hydrofluoric acid solution to produce a liquid reaction mixture. Liquid from the liquid reaction mixture is evaporated under controlled temperature and pressure conditions to near dryness. The nearly-dry residue is prepared for spectral analysis. The presence of a detectable amount of at least one metal analyte is determined for the sample.Type: GrantFiled: July 17, 2003Date of Patent: September 25, 2007Assignee: Air Liquide America L.P.Inventors: Daniel C. Cowles, David S. Bollinger
-
Patent number: 6902937Abstract: This invention relates to methods and apparatus for detecting, quantifying, and/or identifying trace quantities of an anion in the presence of an excess of another anion. One apparatus comprises a sample loop having a first end adapted to be connected to a sample-injection device and a second end adapted to be connected to an inlet of a first separator. An outlet of the first separator has connections to a first waste port and to an inlet of a first anion suppressor. An outlet of the first anion suppressor is connected to a first end of a concentrator and alternatively to waste, the concentrator connected at a second end to a second waste port and alternatively to a pump. The first end of the concentrator is alternatively connected to a second separator inlet, and the second separator is connected at an outlet thereof to an inlet of a second anion suppressor; and an outlet of the second anion suppressor is connected to a mass spectrometer.Type: GrantFiled: July 13, 2001Date of Patent: June 7, 2005Assignee: Air Liquide America, L.P.Inventor: Lynn E. Vanatta
-
Patent number: 6773925Abstract: There are provided a detector agent which is effectively discolored at a lower concentration for various halogen compounds and a method for detecting halogen compounds by use of said detector agent. A detector agent for halogen compounds, which contains curcumin or Bromocresol Green as a discoloring component, and said discoloring component is preferably supported on granular activated alumina.Type: GrantFiled: January 24, 2001Date of Patent: August 10, 2004Assignees: L'Air Liquide Societe Anonyme a Directoire et Conseil de Surveillance Pour l'Etude et l'Exploitation des Procedes Georges Claude, Air Liquide Electronics SystemsInventors: Yoshihiro Ibaraki, Hideji Kawanaka, Hidekazu Ina, Shinichi Ando
-
Publication number: 20040014229Abstract: In a method for efficiently analyzing a posttranslational modification of a protein using no enzyme, a protein or peptide to be analyzed is reacted with an acid (a thioester or hydrazine) under certain conditions. This makes it possible to detect variously modified states of a protein or peptide, whereby the identification of each specific modifying group and the position of each modified amino acid can be efficiently analyzed using a chemical method and a mass spectrometric apparatus.Type: ApplicationFiled: March 14, 2002Publication date: January 22, 2004Applicants: NEC CORPORATION, TOKYO RIKAKIKAI CO., LTD.Inventors: Hirotaka Minagawa, Ichiro Ishida, Akira Tsugita, Takuji Nabetani
-
Patent number: 6673226Abstract: The concentration of chloride ion in an acid copper electroplating bath is determined from the effect that chloride exerts on the copper electrodeposition rate in the presence of organic additives. A cyclic voltammetric stripping (CVS) rate parameter is measured, before and after standard addition of a plating bath sample, in an acid copper electrodeposition solution containing little or no chloride and at least one organic additive. Cross contamination and waste disposal issues associated with the reagents and reaction products involved in chloride titration analyses are avoided. The method may also be applied to analysis of other halides (bromide and iodide) and other solutions.Type: GrantFiled: December 20, 2002Date of Patent: January 6, 2004Assignee: ECI TechnologyInventors: Alex Kogan, Eugene Shalyt, Peter Bratin, Michael Pavlov, Michael James Perpich
-
Publication number: 20030162300Abstract: The invention relates to methods for the hydrolysis of galactomannan compounds and various uses of the hydrolysate.Type: ApplicationFiled: December 19, 2002Publication date: August 28, 2003Inventors: Markwart Kunz, Manfred Vogel, Michael Klingeberg, Eva Ludwig, Mohammad Munir, Frank Rittig
-
Patent number: 6541263Abstract: The present invention is directed to a method of detecting a corticosteroid in a sample by adding an internal standard to a sample suspected of containing a corticosteroid; removing interfering compounds from the sample; placing the sample on an HPLC column equilibrated with a NH4OAc:MeOH solution and collecting an eluent; and analyzing the eluent of the HPLC column with a MS, wherein if contained in the sample, the corticosteroid forms an adduct that is detected by the MS.Type: GrantFiled: February 21, 2001Date of Patent: April 1, 2003Assignee: Euro-Celtique, S.A. LuxembourgInventor: Feng Gao
-
Publication number: 20030003589Abstract: There is disclosed an apparatus and method for detecting and measuring volatile acidic or basic components including ammonia, ammonium, or volatile amines (compound) in a gas or liquid state fluid. Specifically, the present invention provides a PTFE-carrier solid phase indicator film having an ammonia-sensitive indicator dye embedded therein, such that the dye moiety changes color or spectral properties upon exposure to the compound to be detected.Type: ApplicationFiled: May 28, 2002Publication date: January 2, 2003Applicant: Photonic BioSystems, Inc.Inventors: Gamal E. Khalil, David L. Putnam, Todd W. Hubbard
-
Publication number: 20020192837Abstract: The present invention provides a method of detecting trace anions in solutions at a parts per billion (ppb) concentration level or less using existing anion detection technology, by employing a novel sample preparation method conducted prior to injection into a detection unit. The method includes the steps of: adding a precipitant to at least a portion of the solution; evaporating the solution, whereby a trace anion-rich solution is formed; and detecting the level of the trace anions in the trace anion-rich solution to at least a ppb concentration level. As such, any existing detection unit designed for measuring anions, known to those skilled in the art, can be used without modification. This results in a cost and time effective method of detecting trace anions in solution at a ppb concentration level. The invention also provides a system for effectuating the novel method of the present invention.Type: ApplicationFiled: March 8, 2001Publication date: December 19, 2002Applicant: Arch Specialty Chemicals, Inc.Inventors: Steven Van Tendeloo, Peter Steurs
-
Patent number: 6479018Abstract: Detection of an evolving or diffusing gaseous substance emanating from an irradiated or thermolyzed layer of polymeric composition in semiconductor processing or similar processes is disclosed. The evolving or diffusing gaseous substance is detected by spatially disposing from the irradiated or thermolyzed layer a detector layer that includes a compound having leaving groups that are sensitive to the gaseous substance being detected.Type: GrantFiled: January 16, 2001Date of Patent: November 12, 2002Assignee: International Business Machines CorporationInventors: James Patrick Collins, Laird Chandler MacDowell, Wayne Martin Moreau, Michael Santarelli
-
Patent number: 6228650Abstract: In an HF alkylation process where an acid catalyst regeneration column separates HF acid from ASO and water to provide regenerated catalyst for a catalyst circulation stream, and where buildup of ASO in the catalyst circulation stream is encountered, an improved control scheme uses an on-line analyzer/controller to maintain desired concentrations of HF acid, or ASO or water in the catalyst circulation stream. In one embodoment, a continuously flowing catalyst slip stream is piped to the analyzer/controller for simultaneously determining concentration of HF acid, ASO and water, and in a preferred embodiment the ASO concentration is maintained at a desired low level by manipulating temperature of a stripping fluid charged to a lower section of the column. An alternate manipulated variable is temperature of the acid catalyst feed to the regenerator column. Alternate controlled variables are the HF acid, and water concentration in the catalyst circulation stream.Type: GrantFiled: December 7, 1998Date of Patent: May 8, 2001Assignee: Phillips Petroleum CompanyInventors: William P. Moore, Mark A. Clark, Bruce B. Randolph
-
Patent number: 6177279Abstract: A process for extracting inorganic ionic contaminants from a front surface of a silicon wafer for chemical analysis. The wafer is placed in a container upon a support which holds the wafer in a generally level orientation and isolates the wafer to inhibit air circulation over the front surface. Air circulation can introduce contaminants to the extraction fluid, causing a false measurement of contaminants on the wafer. A layer of extraction fluid is deposited upon only the front surface of the wafer and held for a period of time so that contaminants on the front surface are extracted into the layer of fluid. A portion of the layer of fluid is collected by a sampling device for subsequent analysis.Type: GrantFiled: November 12, 1998Date of Patent: January 23, 2001Assignee: MEMC Electronic Materials, Inc.Inventors: Peng Sun, Marty Adams
-
Patent number: 6117686Abstract: The present invention provides a method by which harmful trace gases in a gaseous mixture containing as such harmful halogen gases, halogenated hydrogen gases, acid gases, oxidizing gases, basic gases, organic acid gases, especially halogen gases or halogenated hydrogen gases, are detected by using tetraphenylporphyrin (TPP) and quantitated from a calibration curve constructed therefrom, where the range of detectable concentration is made adjustable so that harmful gas can be detected and quantitated over a broad range of concentration. Furthermore, this invention also provides a method for extending the accessible range of gas concentration by adjusting the sensitivity of the detector material via control of tetraphenylporphyrin concentration in matrix polymer of the detector material, by controlling the gas concentration range via measurement at a specific wavelength(s), and by the use of a plurality of detector materials with pre-set assay sensitivity.Type: GrantFiled: August 3, 1999Date of Patent: September 12, 2000Assignee: Ebara CorporationInventors: Kazunari Tanaka, Chiaki Igarashi, Yoshihiko Sadaoka
-
Patent number: 6103487Abstract: The instant invention provides for a method of inhibiting prenyl-protein transferases and treating cancer which comprises administering to a mammal a prenyl-protein transferase inhibitor which is efficacious in vivo as an inhibitor of geranylgeranyl-protein transferase type I (GGTase-I). The invention also provides for a method of inhibiting farnesyl-protein transferase and geranylgeranyl-protein transferase type I by administering a compound that is a dual inhibitor of both of those prenyl-protein transferases. The invention also provides for a method of identifying such a compound, the method comprising a modified inhibitory assay that incorporates a modulator anion that alters the in vitro potency of prenyl-protein transferase inhibitors in a way that predicts their potency in vivo, thus providing convenient identification of compounds that possess such in vivo activity.Type: GrantFiled: August 26, 1998Date of Patent: August 15, 2000Assignee: Merck & Co., Inc.Inventors: Stanley F. Barnett, David C. Heimbrook, Hans E. Huber, Denis R. Patrick