Abstract: Provided is a centrifugal field-flow fractionation device that can stably press a fixing member toward an inner peripheral surface of a rotor by a wedge-shaped member, even when a relatively large centrifugal force acts on the wedge-shaped member. An arc-shaped (C-shaped) fixing member 17 is provided along an inner peripheral surface of a channel member 16 on a side of a rotation axis of the channel member 16. A wedge-shaped member 18 is attached between opposite ends of the fixing member 17 and applies a force in a direction of spreading the opposite ends apart, to thereby press the fixing member 17 toward the inner peripheral surface of the rotor 14. The wedge-shaped member 18 has a pair of contact surfaces 184 that respectively come into contact with the opposite ends of the fixing member 17.

Abstract: A centrifuge including: a rotary chamber; a rotor installed in the rotary chamber; a driving unit configured to rotate the rotor; a chamber accommodating the rotary chamber, having a door, and configured to house gas therein; and a vacuum pump apparatus configured to exhaust the gas inside the chamber to an outside of the chamber, wherein the chamber is provided with a plurality of gas inlets and a plurality of valves configured to respectively open and close the gas inlets, and wherein all of the plurality of valves are configured to be opened when bringing an internal pressure of the chamber to atmospheric pressure.

Abstract: An apparatus for performing a centrifugal field-flow fractionation is disclosed. In an embodiment of the invention, radial rotary shaft seals are used for sealing the rotating parts of the shaft for carrying out the centrifugal field-flow fractionation and the stationary parts. Furthermore, a separate line is introduced for reducing the pressure differential across these seals. In such way, the driving force driving sample fluid across the seals is reduced, thereby reducing leakage.

Abstract: Processes and methods of recovering desired products from fermentation stillage are presented, including processes and methods of recovering lipids and aqueous materials.

Abstract: The current invention relates to an apparatus for performing a centrifugal field-flow fractionation. In particular, in the apparatus according to the invention, radial rotary shaft seals are used for sealing the rotating parts of the shaft for carrying out the centrifugal field-flow fractionation and the stationary parts. Furthermore, a separate line is introduced for reducing the pressure differential across these seals. In such way, the driving force driving sample fluid across the seals is reduced, thereby reducing leakage.

Abstract: A straight-drum centrifugal dehydration device, wherein extraction of moisture from heavy phase built up in a bowl is facilitated to improve the dehydration effect, and compression efficiency is improved to achieve a reduced load. The straight-drum centrifugal dehydration device, wherein an outer peripheral surface of a rotary drum (21) of a screw conveyor (20) comprises a straight section (24) and a tapered section (25) that spreads outward and away from the straight section, the straight-drum centrifugal dehydration device having an inorganic flocculant feed path for feeding an inorganic flocculant to an inner peripheral surface of the straight section (24) of the rotary drum, and the straight section being provided with an inorganic flocculant addition nozzle (109) communicating with the inorganic flocculant feed path and projecting into an annular space of the bowl and an orifice (108) for adding the inorganic flocculant.

Abstract: A separator includes a rotatable drum having a vertical rotational axis, a disk stack arranged in the drum, an inner gripper and an outer gripper that do not rotate with the drum are configured to discharge mutually-separated liquid phases. A discharge line is assigned to each gripper and is arranged in an associated gripper chamber of the drum. The inner gripper includes an inner gripper shaft and the outer gripper includes an outer gripper shaft both of which shafts protrude axially from the drum. Each associated gripper chamber, with its associated gripper, revolves on different radii with respect to the rotational axis such that a chamber is formed radially between an outer circumference of the inner gripper shaft and an inner circumference of the outer gripper shaft. A fluid is insertable into the chamber through a channel, which fluid is pressable from the chamber into the gripper chambers.

Abstract: A cleaning apparatus for polluted scrubber fluid from an exhaust gas scrubber fluid loop includes means for bleeding off part of the polluted scrubber fluid from the scrubber fluid loop, a disc stack centrifugal separator for separating a pollutant phase and a cleaned scrubber fluid from said part. The separator includes a rotor enclosing a separation space with a stack of separating discs, a separator inlet extends into the separating space, a first separator outlet for cleaned scrubber fluid extending from said separating space, and a second separator outlet for the pollutant phase extending from the separating space. The cleaning apparatus includes means for conducting the part to the separator inlet, and means for discharging the cleaned scrubber fluid from the first separator outlet, and means for collecting the pollutant phase from the second separator outlet.

Abstract: A microfluidic flow cell for removably interfacing with a removable-member for performing a reaction therebetween. The microfluidic flow cell device comprises at least one reaction portion defining with the removable-member a reaction chamber when in an interfaced position thereof. The microfluidic flow cell comprises at least one fluid-receiving portion for receiving a fluid therein and being in fluid communication with the reaction chamber. When the microfluidic flow cell and the removable-member are in the interfaced position, the cell is adapted to allow for the fluid in the fluid-receiving portion to flow to the reaction chamber. Devices, systems and methods comprising this microfluidic flow cell are also disclosed.

Abstract: This invention is directed to a method of collecting and separating whole blood into components. The method includes the steps of adding an anticoagulant having an acidic pH to a bag for collecting and/or separating whole blood, collecting whole blood in the bag, loading the bag containing anticoagulated whole blood on a rotor, spinning the bag on the rotor to separate the whole blood into at least one component; and squeezing the bag on the rotor to push the component from the separation bag into at least one satellite bag.

Abstract: Provided are closed-cycle continuous flow separator systems for isolating target cell populations, which comprises in operable connection, a binding area for binding a target cell to a binding particle; a first continuous flow centrifuge for separating target cell bound binding particles from non-target cells; a de-binding area for de-binding the target cell from the binding particle; and a second continuous flow centrifuge for separating the target cell from the binding particle.

Abstract: A microfluidic device and a method of fabricating the microfluidic device are provided. The microfluidic device includes: a platform including an upper substrate and a lower substrate that are bonded to face each other; a microfluidic structure obtained by forming grooves in the lower substrate; a lower substrate protrusion pattern including an outline protrusion that protrudes from the lower substrate toward the upper substrate along an outline of the microfluidic structure; and an adhesive layer disposed between the lower substrate protrusion pattern and the upper substrate in order to bond the upper substrate and the lower substrate to each other. The lower substrate protrusion pattern only supports the upper substrate, and remaining portions of the lower substrate except for the lower substrate protrusion pattern do not have structures for supporting the upper substrate.

Abstract: The present invention describes a centrifuge system and method for improving the separation of entrained solids from a solution. The system and method introduces compressed gas to a fluid containing entrained solids to reduce the density and viscosity of the fluid to promote the settling of particles within the solution.

Abstract: A separator device comprises a cylindrical separation chamber within which a motor-driven rotor is situated. The rotor has vanes. In operation, an inflowing mixture enters through an inlet and is subjected to centrifugal force imposed by the rotation of the rotor. A lighter liquid fraction leaves through an annular outlet, and a heavier liquid fraction leaves through an annular outlet. Solids pass through a screen to a region where rotational flow is reduced or absent. The solids in the region are fluidized by liquid passing through the screen, and are extracted from outlets. Control means is provided to control operation of the device in response to changes in the incoming mixture.

Abstract: Tubular labels and contaminants can be removed from containers and/or bottles of plastic material to be recycled, by subjecting the containers and/or bottles to a first weak mechanical washing and slow centrifugating action, followed by a separation step for separating the removed labels and contaminants from the containers. The containers are subsequently subjected to a second strong mechanical washing and fast centrifugating action for the removal from the containers and/or bottles of any residual labels and contaminants.

Abstract: A powder spraycoating facility's powder recovery unit comprising a cyclone separator to separate coating powder from an air-powder mixed flow. The cyclone separator comprises a cyclone section separating powder from the powder-air mixed flow and a supply bin in the form of a downward-projecting extension of the cyclone section, said unit further comprising a powder passage in said cyclone from the cyclone section into the supply bin, said passage being devoid of powder blocking elements while being powder-tight relative to the atmosphere.

Abstract: A clean-in-place decanter centrifuge for processing a combined liquid and solid material to separate the solid material from the liquid. The centrifuge is designed for use in the food processing industry, particularly for dairy products, and therefore has fluid injectors for cleaning all surfaces within the centrifuge including the opposed mating surfaces which function as non-contacting seal mechanisms. The centrifuge has no metal-to-metal contact areas within the interior of the bowl and scroll assembly. In one embodiment, the outer wall of the bowl and scroll assembly comprises a plurality of drain lines located in the rear wall section of the bowl to allow essentially all liquid to drain from the bowl and scroll assembly. In another embodiment, the bowl hub comprises at least one drain line to allow lubrication oil to drain into said cavity and prevent ingress of lubrication oil into said bowl and scroll assembly.

Abstract: A centrifugal separator assembly including a polygonal separator chamber formed of planar wall sections joined with each other to provide a substantially gas tight structure and having at least four pairs of planar opposite wall sections. The chamber includes a tapered portion formed by having a first inward bending in each of the wall sections. The tapered portion extends as a discharge channel for separated particles from the separator chamber, which discharge channel is formed of first and second pairs of opposite wall sections being perpendicular to each other. In the discharge channel for separated particles, the first pair of wall sections extends into the area between the second pair of wall sections.

Abstract: A centrifuge for processing blood and blood components in a processing bag connected to at least one secondary bag comprises a rotor for spinning a processing bag and separating a content thereof in at least two components, and a squeezing member for exposing a processing bag to an external pressure and causing a transfer of a separated component from a processing bag into a secondary bag. Electrically powered devices, such as valves and photocells, are mounted on the rotor for controlling a transfer of fluid from a processing bag into a secondary bag. An electrical power supply system supplies the electrically powered devices with electrical power through the rotor.

Abstract: A system for automatically collecting and separating whole blood into its components is described. The system includes a console, which contains all motors, pumps, sensors, valves and control circuitry, and a unique disposable set that includes a cassette supporting a centrifuge with an improved design, pump interfaces with an improved design, component and solution bags, and tubing. Various processes are implemented using a specific disposable set for each process which allows automatic identification of the process to be performed the console.

Abstract: In a method of rapidly lowering the rotary speed of a rotating rotor body in a centrifugal separator the lowering of the rotary speed is initiated, when a disturbing unbalance or vibrations have occurred. A space between the rotor body and a stationary casing which surrounds the rotor body is supplied with foam or with an aerosol of a liquid in a gas, when unbalance or vibrations over a certain level have occurred. The rotor body is retarded by the friction, which is obtained between the rotor body, the foam or aerosol and the casing. In an arrangement to lower the rotary speed of a rotating rotor body in a centrifugal separator the lowering is initiated when a disturbing unbalance or disturbing vibrations has occurred. At a certain unbalance or certain vibration level, a foam generating device or a device that creates an aerosol for the purpose of filling a space between the rotor body and a casing which surrounds the same with foam or aerosol is activated.

Abstract: The invention relates to a centrifuge provided with a blood bag system having an upper and lower outlet for separation of blood constituents, containing a rotor which can be driven in a rotative manner about a hub, wherein at least one conventional whole blood bag equipped with an upper outlet and with a lower outlet can be positioned vertically in this blood bag, while the whole blood bag can be arranged on the rotor in such a way that one outlet of the whole blood bag is bent in a radial direction, and the opposite outlet of the whole blood bag is bent in the other radial direction, so that the entire whole blood bag and the outlets thereof adopt an approximately Z- or S-shaped form in its functional position. In this case it is preferred that the upper outlet of the whole blood bag lie radially toward the interior and the lower outlet of the whole blood bag lie radially toward the exterior of the whole blood bag.

Abstract: Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Abstract: A centrifuge with an associated container system in the form of cassettes for separation and/or treatment of blood or blood components. The centrifuge comprises a rotor having a central compartment in the form of a tubular shaft cavity extending concentrically with the axis of rotation of the rotor and an annular separation compartment which is arranged around said cavity at the upper part thereof. A first container system arranged in the rotor for washing of blood cells comprises a round bag with two or more flexible secondary containers connected thereto, of which at least one contains a treatment liquid, and a tubular sleeve adapted to the shaft cavity of the rotor. The secondary containers stand in the sleeve resting against each other, and the round bag is mounted on a projecting flange at the upper part of the sleeve.

Abstract: Method of separating cells in a centrifuge, preferably for producing platelets. A cell suspension is provided in a processing bag and is centrifuged. The cell enriched fraction is transferred to a storage bag via an outlet tube. The outlet tube is arranged with a portion thereof in a position adjacent the periphery of the centrifuge. When the enriched fraction is transferred through the outlet tube placed at the periphery of the centrifuge and during centrifugation, the outlet tube operates as a cell trap and the enriched fraction is further separated. Preferably, the cell suspension is buffy coat and the enriched fraction comprises platelets. The corresponding bag assembly comprises a processing bag intended to enclose the cell suspension. The processing bag is placed in a centrifuge rotor for separating the cells into a fraction enriched on platelets by centrifugation.

Abstract: A separation set for blood component preparation and similar separations for use in a centrifuge rotor, the set including a plate-like separation container made of a flexible material, an annular pinch valve which is mounted on and divides the separation container into a central section and an annular outer section, a first component container which is connected to the center of the separation container, a second component container which is connected to the circumference of the separation container, and a blood withdrawal tube for supplying blood to the outer section. The blood is separated in the outer section into plasma, buffy coat and red blood cells. Then the plasma is displaced to the first component container and the buffy coat to the central section where it is enclosed through the action of the pinch valve. The separation set with the pinch valve is then removed from the centrifuge and the red blood cells are transferred to the second component container.

Abstract: A flow-through microcentrifuge comprising a container in which a sample is placed, and a power source capable of rotating the container around an axis. High speed rotation causes the components of the sample to separate according to their respective densities. Pressurized gas, a flowing liquid, electromagnetism, or an engine can power rotation of the container. Due to the small size of the flow-through microcentrifuge, speeds can reach up to 600,000 rpm, with a corresponding increase in centrifugal acceleration up to 1,500,000 g. In addition to separation, the flow-through microcentrifuge can resuspend pelleted material in a liquid by rotating in one direction and then in the opposite direction, repeatedly. The flow-through microcentrifuge is also able to mix two or more reagents using this method. The flow-through microcentrifuge is modular in nature, meaning two or more can be placed together in any configuration and run by the same power source.

Abstract: Apparatus for separating a biological component from a biological fluid are disclosed. The apparatus includes a chamber for receiving a biological fluid including a biological component, and a rotor for creating a centrifugal field within the chamber. A source of particles may be included wherein the particles have a binding site for selectively binding to the biological component. The particles may be aseptically introduced into the chamber. The apparatus may withdraw whole blood from a donor, separate the whole blood to obtain a target cell population and return a selected one of either the target cell population or at least a portion of the whole blood remainder to the donor or patient. A disposable separation inset for use in conjunction with a rotatable separation device such as the apparatus described above may also be provided.

Abstract: Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Abstract: A rotor for collecting and centrifuging biological fluids in a range of volumes. The rotor includes an elastic impermeable diaphragm which defines at least a portion of a variable-volume processing chamber, where the fluid is centrifuged. The rotor includes a rigid mounting member, to which the diaphragm is mounted and which is held and spun by a chuck. Preferably, this rigid mounting member includes a boundary wall which together with the elastic diaphragm defines the chamber. The boundary wall may be a substantially imperforate circular wall which extends to the periphery of the processing chamber but defining one opening, preferably near the axis of rotation, permitting a conduit or conduits to pass therethrough so as to be in fluid communication with the processing chamber. The rotor may include a separate structure for controlling the flow of liquid out of the chamber into the conduit.

Abstract: A rotor for collecting and centrifuging biological fluids in a range of volumes. The rotor includes an elastic impermeable diaphragm which defines at least a portion of a variable-volume processing chamber, where the fluid is centrifuged. The rotor includes a rigid mounting member, to which the diaphragm is mounted and which is held and spun by a chuck. Preferably, this rigid mounting member includes a boundary wall which together with the elastic diaphragm defines the chamber. The boundary wall may be a substantially imperforate circular wall which extends to the periphery of the processing chamber but defining one opening, preferably near the axis of rotation, permitting a conduit or conduits to pass therethrough so as to be in fluid communication with the processing chamber. The rotor may include a separate structure for controlling the flow of liquid out of the chamber into the conduit.

Abstract: A system for separating flowable media into its components includes a pump delivering a flowing stream of the media, a separation tube through which the stream of the flowable media is passed, a mechanism for spinning the stream of flowable media about the axis of the separation tube at sufficient rotational speed that centrifugal force within the stream causes the media components to separate into component radial layers, according to their specific gravities, an extraction conduit for selectively extracting one or more of the radial layers from the separation tube, and monitoring and automatic feed back elements for measuring the component content as the media enters and exits the separation tube and for adjusting the rotational speed of the media.

Abstract: A system for separating a fluid having heavier and lighter components. The system includes a rotor having a rigid mounting member and an elastic diaphragm attached to the mounting member, the diaphragm defining a chamber. The system also includes a chuck for holding the rigid mounting member of the rotor and for spinning the rotor around an axis. The pressure of a control fluid, preferably a control gas, disposed adjacent the rotor's diaphragm is varied in order to control the volume of the rotor. Pressurizing the control gas causes fluid to flow out of the rotor; applying a vacuum to the diaphragm draws fluid into the rotor.

Abstract: A reverse filter centrifugal machine has a self-contained, rotatably mounted basket (7) in a housing (1), provided with radial filtrate passages (11) and capable of receiving an overpressure or a negative pressure, as well as a lid (19) that closes the free front side of the basket. The basket and the lid are axially movable with respect to one another. A feed opening for the suspension to be filtered is arranged in the lid and a feed pipe (21) is sealingly inserted through the feed opening. The feed pipe (21) is rotatably mounted around its longitudinal axis and can be rotated together with the basket (7) around this axis.

Abstract: A water-conducting lance, fitted with a spray nozzle at an end thereof, is fixed to the top of a massecuite-separating centrifuge which has a rotating basket, to dispose the nozzle in adjacency to the top of the basket. The nozzle addresses the top of the basket, perpendicularly, and sprays pre-wetting water onto sugar crystals thereat, to insure a good mix of the crystals with subsequent mixing liquid (also water) in a mixing liquid zone, in order that a lump-free high brix magma will be produced.

Abstract: An inverted filter centrifuge consisting of a drum arranged to rotate freely in a housing and having radial filtrate outlets; a cover closing one of its free frontal areas, the drum and the cover being mutually axially movable; a filler aperture in the cover for the suspension to be filtered and a filler pipe passing through the filler aperture. The filler aperture in the cover can be hermetically sealed by a locking component rotating together with the drum which is disconnected from the filler pipe in a manner to avoid friction.

Abstract: The peeling chamber in a head of a centrifuge has an upstream barrier chamber that seals it off from the atmosphere. A barrier disk secured to a peeler extends into the barrier chamber. Compressed gas is supplied to between barrier disk and peeler through a channel to prevent gas from escaping from the solvent. Another channel supplies liquid to the barrier chamber. Solvent from the periphery is supplied to the barrier chamber through a channel and simultaneously by the peeler through the barrier-liquid channel. An area of separation becomes established between the two liquids in the barrier chamber. If any solid particles enter the barrier chamber as the result of gas leaving the solvent, they will dissolve again in the solvent in the periphery of the barrier chamber and will be prevented from making the chamber malfunction.

Abstract: An invertible filter centrifuge is provided comprising a rotary drum which is mounted in a cantilever manner in a housing and has radial passages for filtrate, a lid which is axially displaceable relative to the drum and closes the free front side of the latter, a filler opening on the lid for suspension to be filtered, and filler pipe which, on the one hand, is secured to the housing and, on the other hand, penetrates the filler opening, the outlet end of the filler pipe being located inside the drum during the centrifuging operation, characterized in that for varying the pressure in the drum (16), the filler pipe (26) is connectable to a pressurization or depressurization source (44) and is sealed by a combined rotary and sliding seal (45, 46, 47, 53) on said lid (25).

Abstract: To separate minerals, they are mde up into a slurry applied through feed pipe 46 to a vertical-axis spiralinder 32 spinning on its axis to generate 10 g centrifugal force. The spiralinder is also subjected to axial vibration at 5 to 10 Hz. A film of slurry is held centrifugally to the internal surface of the spiralinder and kept in suspension by the vibration. The denser (i.e. higher specific gravity) particles in the slurry tend to be most firmly pinned centrifugally. The lightest particles thus drop first into the trough 44 and are dumped by switchable box 45. The centrifugal spinning is then slowed and the dense particles scoured off by wash water. The whole cycle is then repeated.

Abstract: To separate minerals, they are made up into a slurry A applied to a hollow tapered cylinder 301 spinning on its axis to generate 10 g centrifugal force. The cylinder 301 is also subjected to axial vibration at 5 to 10 Hz. The cylinder widens at a half-angle of 1.degree., and its axis is inclined at 2.degree. upwardly in the direction of widening. A film of slurry is held centrifugally to the internal surface of the cylinder and kept in suspension by the vibration. The denser (i.e. higher specific gravity) particles in the slurry tend to move preferentially radially outwardly (centrifugally) and to move downwardly in the boundary layer (under Earth's gravity). The action of the washing water B is to displace waste accidentally entrained with the higher-specific-gravity-particles. The valuable higher-specific-gravity particles overflow downwardly continuously at C and are collected.

Abstract: The device comprises a single needle circuit having lines for admitting whole blood drawn from a patient to a continuously rotating rotor, re-introducing red cells and collecting plasma, the lines being respectively connected to the three outlets of a coupling static block rigidly attached to the rotor, two photocell-lightsource assemblies being further provided for automatically cyclically switching over the blood pick up and red cells introduction steps in the device steady state condition of operation.

Abstract: A centrifuge that has a vertical axis of rotation and that is intended for separating or clarifying mixtures of liquids has a drum with a skimming compartment that accommodates a skimmer for diverting a clarified or separated liquid phase. Above the skimming compartment is a blocking compartment that can be filled with a blocking fluid into which a sealing disk that is rigidly connected to the skimmer is immersed and that is intended to prevent atmospheric air from getting into the skimming compartment. The skimmer and sealing disk are positioned in the compartments at a certain distance from the rotating components of the drum. The portions of the compartments communicate with each other that are below the sealing disk and above the skimmer and are connected to a channel through which a gas that is under higher-than-atmospheric pressure can be supplied to the chambers to prevent blocking fluid from squirting out of the blocking compartment into the skimming compartment.