Abstract: The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some embodiments, the present invention provides methods and compositions for generation of long chain peracids. Certain embodiments of the present invention find particular use in applications involving cleaning, bleaching and disinfecting.

Abstract: The present invention relates to a water-soluble pouch comprising a laundry detergent composition comprising reactive dye.

Abstract: The present invention provides novel cellulase fusion proteins, preparations of cellulase fusion proteins and compositions of cellulase fusion proteins. The present invention further provides cellulase expression vectors, host cells expressing cellulase and methods for preparing such vectors and cells. Uses of cellulases, cellulase preparations and cellulase compositions in the textile, detergent, pulp and paper industries are also provided.

Abstract: Disclosed herein are enzyme powders comprising a spray-dried formulation of at least one CE-7 esterase, at least one oligosaccharide excipient, and optionally at least one surfactant. Also disclosed herein is a process for producing peroxycarboxylic acids from carboxylic acid esters using the aforementioned enzyme powders. Further, disinfectant and laundry care formulations comprising the peracids produced by the processes described herein are provided.

Abstract: Disclosed herein is a method for stabilization of the perhydrolase activity of the CE-7 esterase in a formulation with a carboxylic acid ester that employs the addition of a buffering agent, substantially undissolved, to the mixture of the CE-7 esterase and the carboxylic acid ester. Further, disinfectant and laundry care formulations comprising the peracids produced by the processes described herein are provided.

Abstract: The present invention is directed to novel compositions and methods for enzymatic one-step pretreatment of cellulosic, cellulosic-containing (e.g., cotton and cotton-containing) and non-cellulosic textiles, fibers and fabrics. Pretreatment comprises scouring and bleaching, and optionally, desizing of the textiles.

Abstract: The invention is related to mild pretreatment or preparation process as well as combined scoring and bleaching composition for cellulose-based textile material. The process comprises a sequential or simultaneous scouring step with an enzyme composition acting on the non-cellulosic material on outer layers of cellulosic fibers and a reducing bleaching step with a reducing bleaching agent. The reducing bleaching agent is preferably dithionite. In the process no adjustment of pH and temperature are required. The process is environmentally friendly because no causticizing and oxidizing agents are required to achieve the desired lightness and wettability. Due to the mild pretreatment conditions tensile strength of the fabric is better than that achieved with conventional pretreatments.

Abstract: A process is provided to produce a concentrated aqueous peracid solution in situ using at least one enzyme having perhydrolase activity in the presence of hydrogen peroxide (at a concentration of at least 500 mM) under neutral to acidic reaction conditions from suitable carboxylic acid esters (including glycerides) and/or amides substrates. The concentrated peracid solution produced is sufficient for use in a variety of disinfection and/or bleaching applications.

Abstract: The present invention relates to the use of biocide (e.g., bactericidal enzyme) to target pathogens. In particular, the present invention provides biocides for use in health care (e.g., human and veterinary), agriculture (e.g., animal and plant production), and food processing (e.g., water purification).

Abstract: A method is provided for producing peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted in situ with an inorganic peroxide such as hydrogen peroxide in the presence of a perhydrolase catalyst derived from a Lactobacillus sp. to produce peroxycarboxylic acids.

Abstract: A process is provided to produce a concentrated aqueous peracid solution in situ using at least one enzyme having perhydrolase activity in the presence of hydrogen peroxide (at a concentration of at least 500 mM) under neutral to acidic reaction conditions from suitable carboxylic acid esters (including glycerides) and/or amides substrates. The concentrated peracid solution produced is sufficient for use in a variety of disinfection and/or bleaching applications.

Abstract: The present invention provides an endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.

Abstract: The invention relates to novel perhydrolases, derived from the protease Carlsberg by amino acid exchange in positions 11, 15, 21, 38, 50, 54, 58, 77, 83, 89, 93, 96, 107, 117, 120, 134, 135, 136, 140, 147, 150, 154, 155, 160, 161, 171, 179, 180, 181, 194, 205, 208, 213, 216, 217, 238, 239, 251, 253, 257, and/or 261. The invention further relates to methods for production of said novel perhydrolases, products comprising said novel perhydrolases, particularly bodycare, haircare, shampoo, hair-dyeing, hair-bleaching, oral-care, dental-dare, dental-prosthesis-care, cosmetic, therapeutic (textile) washing, cleaning, rinsing, handwash, washing-up and dish-washing products, and corresponding applications of said novel perhydrolases.

Abstract: The present invention is related to glucoamylases having at least 80% sequence identity to a Trichoderma glucoamylase having the sequence of SEQ ID NO: 4 and biologically functional fragments thereof. The invention is also related to DNA sequences coding for the glucoamylases, vectors and host cells incorporating the DNA sequences, enzyme compositions and methods of using the glucoamylases in various applications.

Abstract: A cleaning composition utilizing an anionically modified catechol in combination with a soil suspending polymer to remove clay and plant-derived polyphenolic compound soils.

Abstract: The invention is directed to a liquid laundry detergent composition comprising at least one detergent ingredient selected from the group consisting of anionic surfactant, zwitterionic surfactant, amphoteric surfactant, and mixtures thereof; a coacervate phase forming cationic polymer; and one or more fabric care ingredients selected from the group consisting of one or more cationic silicone polymers comprising one or more polysiloxane units and one or more nitrogen moieties; one or more amino silicone polymers; one or more nitrogen-free silicone polymers; and mixtures thereof; and a liquid carrier for providing cleaning and fabric care benefits. A process for preparing such compositions, a method for treating substrates, a method for providing certain fabric care benefits and the use of such compositions are also described.

Abstract: The invention is directed to liquid laundry detergent compositions for treating non-keratinous substrates under domestic wash conditions, such composition comprise (A) at least one surfactant selected from the group consisting of anionic surfactants, nonionic surfactants, zwitterionic surfactants, amphoteric surfactants, and combinations thereof; (B) a silicone blend comprising a non-functionalized silicone and a functionalized silicone; and (C) at least one additional non-silicone laundry adjunct selected from the group consisting of detergent builders, detersive enzymes, dye transfer inhibiting agents, and combinations thereof. The claimed compositions are further essentially free of any coacervate phase-forming polymer and essentially free of any cationic deposition aid.

Abstract: The invention is directed to a liquid laundry detergent composition comprising at least one detergent ingredient selected from the group consisting of anionic surfactant, zwitterionic surfactant, amphoteric surfactant, and mixtures thereof; a coacervate phase forming cationic polymer; and one or more fabric care ingredients selected from the group consisting of one or more cationic silicone polymers comprising one or more polysiloxane units and one or more nitrogen moieties; one or more amino silicone polymers; one or more nitrogen-free silicone polymers; and mixtures thereof; and a liquid carrier for providing cleaning and fabric care benefits. A process for preparing such compositions, a method for treating substrates, a method for providing certain fabric care benefits and the use of such compositions are also described.

Abstract: The present invention relates to an article comprising: (a) a liquid composition comprising: (i) enzyme; and (ii) from 0% to 10% (by weight of said liquid composition) free water, preferably 0% to 5% free water; and (iii) carboxylic acid comprising 5 carbon atoms or less, and 1 or 2 carboxy groups; and (iv) chelating agent; and (v) enzyme stabilizing metal ion system consisting of calcium ions and magnesium ions, present in a weight ratio of calcium ion to magnesium ion of from 1:1 to 4:1; and (vi) from 0% to 0.2% (by weight of said liquid composition) source of borate ions; and (b) a water-soluble polymeric material that is capable of being cross-linked by borate ions, preferably a water-soluble polymeric material comprising poly-vinyl alcohol.

Abstract: Enzyme-containing formulations having improved stability and enzymatic activity in liquid medium, comprising one or more protease enzymes produced from any Bacillus bacteria, at least about 5% alkali metal halide salt, and at least about 50% polyol. Also disclosed are methods for making such formulations.

Abstract: There is provided an antibody granule, consisting essentially of one or more antibodies, or fragments derived thereof, granulated with an alkali metal salt. Also provided is a process for preparing said antibody granules. The granules can be used in an enzymatic stain bleaching or anti dye-transfer composition.

Abstract: Laundry or cleaning composition comprising: (a) a catalytically effective amount, preferably from about 1 ppb to about 99.9%, of a transition-metal bleach catalyst which is a complex of a transition-metal and a cross-bridged macropolycyclic ligand; and (b) at least about 0.1% of one or more laundry or cleaning adjunct materials, preferably comprising an oxygen bleaching agent. Preferred compositions are laundry compositions and automatic dishwashing detergents which provide enhanced cleaning/bleaching benefits through the use of such catalysts.

Abstract: The present invention relates to a method for the controlled availability formulation components, such as organic catalysts, into a wash solution. More particularly, the present invention relates to products and bleaching compositions containing such formulation components and laundry methods employing such formulation components.

Abstract: Laundry product compositions containing a stable mixture of at least one water insoluble fabric care benefit agent and at least one delivery enhancing agent that is preferably a dispersible polyolefin, polymer latex, or mixture thereof. Detergent laundry product compositions containing from about 1% to about 80%, by weight of the composition, of a detersive surfactant that is an anionic surfactant, cationic surfactant, nonionic surfactant, amphoteric surfactant, zwitterionic surfactant, or a mixture thereof; from about 0.1% to about 10%, by weight of the composition, of a water insoluble fabric care benefit agent; from about 0.01% to about 5%, by weight of the composition, of a delivery enhancing agent; and wherein the ratio of the delivery enhancing agent to the fabric care benefit agent is from about 1:50 to about 1:1.

Abstract: Laundry product compositions containing a stable mixture of at least one water insoluble fabric care benefit agent and at least one delivery enhancing agent that is preferably a silicone derivative. Detergent laundry product compositions containing from about 1% to about 80%, by weight of the composition, of a detersive surfactant that is an anionic surfactant, cationic surfactant, nonionic surfactant, amphoteric surfactant, zwitterionic surfactant, or a mixture thereof; from about 0.1% to about 10%, by weight of the composition, of a water insoluble fabric care benefit agent; from about 0.01% to about 5%, by weight of the composition, of a delivery enhancing agent; and wherein the ratio of the delivery enhancing agent to the fabric care benefit agent is from about 1:50 to about 1:1.

Abstract: Novel bleaching compositions comprising organic catalyst compounds, preferably branched organic catalyst compounds, and an anionic surfactant, methods for laundering fabrics using such bleaching compositions, and laundry additive products containing such bleaching compositions are provided.

Abstract: The present invention relates to fabric care compositions comprising one or more amino acid sequence(s) comprising a Cellulose Binding Domain for providing fabric care. In a further embodiment, the present invention relates to fabric care compositions wherein the amino acid sequence comprising one or more cellulose binding domains is linked to a softening protein.

Abstract: Formulation components such as bleach boosting compounds selected from the group consisting of bleach boosters comprising quaternary imine cations, zwitterions, polyions having a net charge of from about +3 to about 3 and mixtures thereof, bleaching species comprising oxariridinium cations, zwitterions, polyions having a net charge of from about +3 to about ?3 and mixtures thereof, and mixtures thereof are disclosed. The bleach boosting compounds increase bleaching effectiveness even in lower temperature solutions and provides improved stability toward unwanted boosting compound decomposition. The bleach boosting compounds are ideally suited for inclusion into bleaching compositions including those with detersive surfactants and enzymes. Also provided is a method for laundering a fabric employing the bleach compounds, a laundry additive product employing the bleach boosting compounds.

Abstract: Solid block alkaline detergent compositions are disclosed comprising a source of alkalinity, and other detergent additives including sequestrants. The solid block detergents of the invention used a mixed inorganic and organic sequestrant composition that successfully softens service water used in manufacturing aqueous detergents from the composition, but also obtains substantially improved organic soil removal on dishware or flatware. The solid block detergents of the invention comprise large masses of the chemical ingredients having a weight of greater than about 500 grams in a solid block product format that is typically dispensed using a spray on water dispenser that creates an aqueous concentrate that is used in a washing machine.

Abstract: The present invention relates to a process for the selective oxidation of toluene derivatives by microbial peroxidases from microorganisms of the genus Coprinus.

Abstract: The present invention relates to cationic organic catalyst compound bleach systems and methods using such bleach systems to increase color safety during laundering fabrics, especially colored fabrics. More particularly, this invention relates to bleach systems comprising cationic, quaternary imine bleach boosting compounds, cationic, quarternary oxaziridinium bleaching species and mixtures thereof, and methods employing such bleach systems in the laundering of fabrics, especially colored fabrics.

Abstract: The present invention relates to zwitterionic organic catalyst compound bleach systems and methods for using such bleach systems to increase color safety during laundering of fabrics, especially colored fabrics.

Abstract: Formulation components such as bleach boosting compounds selected from the group consisting of bleach boosters comprising quaternary imine cations, zwitterions, polyions having a net charge of from about +3 to about −3 and mixtures thereof, bleaching species comprising oxaziridinium cations, zwitterions, polyions having a net charge of from about +3 to about −3 and mixtures thereof, are disclosed. The bleach boosting compounds increase bleaching effectiveness even in lower temperature solutions and provides improved stability toward unwanted boosting compound decomposition.

Abstract: A transparent consumer product, such as an aqueous heavy duty liquid having colorant dye, in a clear bottle, wherein the material of which said bottle is made comprises fluorescent dye to protect the colorant dye. The f-dye may, alternatively or in addition to, be present in a clear label on such bottle.

Abstract: Agents for cleaning hard surfaces, such as crockery, containing a &bgr;-glucanase and compatible cleaning constituents, and having good cleaning effect on polysaccharide stains.

Abstract: There is provided a targeted bleaching composition comprising an organic substance which forms a complex with a transition metal, the complex catalyzing bleaching of a substrate by a precursor selected from atmospheric oxygen and/or a peroxyl species. The complex is bound to a recognizing portion having a high binding affinity for stains present on fabrics.

Abstract: There is provided a method of delivering a benefit agent whereby a benefit agent is first loaded to a surface and subsequently unloaded and transferred and delivered to a second surface. More in particular, the benefit agent is first loaded onto a garment during a laundering process, and subsequently delivered to another surface. The benefit agents can be fragrance agents, perfumes, colour enhancers, fabric softening agents, polymeric lubricants, photoprotective agents, latexes, resins, dye fixative agents, encapsulated materials, antioxidants, insecticides, soil repelling agents, soil release agents, and cellulose fibers.

Abstract: The present invention relates to lipase variants having at least 90% identity to the wild-type lipase derived from Humicola lanuginosa strain DSM 4109 and having a certain distribution of electrically charged amino acids. The present invention also relates to detergents comprising such lipases.

Abstract: The invention relates to a variant of a parent Termamyl-like a-amylase, which variant has a-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent a-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency and specific activity.

Abstract: The present invention relates to cleaning compositions comprising a protease variant.

Abstract: Detergent compositions and fabric conditioning compositions which include from about 0.01% to about 5.0%, by weight, of polyelectolyte complexes having a compatible charge-balancing polymeric anion with at least 3 anionic groups and a total net charge of at least 4 negative charges.

Abstract: The present invention provides highly impact-resistant, water-soluble or water dispersible, low-dust granules comprising an active ingredient and methods for obtaining the same.

Abstract: A method of delivering a benefit agent to a selected area of a fabric for exerting a predetermined activity, wherein the area is pre-treated with a multi-specific binding molecule which has a high binding affinity to said area through one specificity and is capable of binding to said benefit agent through another specificity, followed by contacting said pre-treated area with said benefit agent, to enhance said pre-determined activity to said area. Preferably, the binding molecule is an antibody or fragment thereof, or a fusion protein comprising a cellulose binding domain and a domain having a high binding affinity to another ligand which is directed to said benefit agent. The method is useful for stain removal, perfume delivery, and treating collars and cuffs for wear.

Abstract: A method of delivering a benefit agent to fabric for exerting a pre-determined activity, wherein the fabric is pre-treated with a multi-specific binding molecule which has a high binding affinity to the fabric through one specificity and is capable of binding to the benefit agent through another specificity, followed by contacting the pre-treated fabric with the benefit agent, to enhance the pre-determined activity to the fabric. Preferably, the binding molecule is an antibody or fragment thereof, or a fusion protein comprising a cellulose binding domain and a domain having a high binding affinity to another ligand which is directed to said benefit agent. The method is useful for example for stain removal, perfume delivery, and treating collars and cuffs for wear.

Abstract: The present invention relates to laundry detergent compositions which can optionally comprise bleach, said compositions comprising a fabric enhancement system, said fabric enhancement system comprising one or more modified polyamine compounds.

Abstract: A composition for simultaneous cleaning and decontaminating a device. The composition is a per-compound oxidant in an amount effective for decontaminating the device and an enzyme in an amount effective for cleaning the device. The device may be a medical device such as an endoscope or kidney dialyzer and a plurality of devices can be cleaned using the same composition. The composition may additionally contain a corrosion inhibitor in an amount effective to prevent corrosion of a metal, a chelator, a buffer, a dye and combinations thereof.

Abstract: The present invention relates to laundry detergent compositions which can optionally comprise bleach, said compositions comprising from about 0.01% to about 10% by weight, of a polyalkyleneimine. These detergent compositions provide fabric appearance benefits inter alia mitigation of fabric damage via bleaching agents.

Abstract: The present invention relates to polypeptides with reduced immune response including reduced allergenicity having one or more amino acid residues being substituted with other amino acid residues and/or having coupled one or more polymeric molecules in the vicinity of the polypeptides metal binding site, a method for preparing modified polypeptides of the invention, the use of the polypeptide for reducing the immunogenicity and allergenicity and compositions comprising the polypeptide.

Abstract: Detergent compositions comprise a water-soluble builder, an enzyme and a polymeric dye transfer inhibiting agent, wherein a means is provided for delaying the release of the enzyme relative to the release of the water-soluble builder to the wash solution. The time to achieve a concentration that is 50% of the ultimate concentration of the water-soluble builder is less than 60 seconds, and the time to achieve a concentration that is 50% of the ultimate concentration of the enzyme is more than 90 seconds.

Abstract: The present invention relates to a modified enzyme which comprises a catalytically active amino acid sequence of a cellulolytic enzyme linked to an amino acid sequence comprising a Cellulose Binding Domain (CBD) having a relative binding constant (Kr-a) for binding to amorphous cellulose higher than 2.4 l/gcellulose, preferably higher than 3.5 l/gcellulose, more preferably higher than 4 l/gcellulose, for selective binding and hydrolysis of amorphous cellulose of cotton containing fabrics in a laundry and/or fabric care application. The present invention further relates to laundry detergent and/or fabric care compositions comprising this modified enzyme.