Starch Or Derivative Patents (Class 514/60)
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Publication number: 20130196949Abstract: The present invention relates to hydroxyalkyl starch or a pharmaceutical preparation thereof for the treatment of cancer, tumor or tumor associated diseases, especially by effectively reducing tumor growth rate and inhibiting tumor growth and wherein the hydroxyalkyl starch has a mean molecular weight (MW) above 20 and below 1300 kDa and a molar substitution (MS) in the range of from 0.1 to 1.5, wherein the alkylation may be an ethylation, propylation or butylation or mixes thereof; and wherein the alkyl may be further substituted.Type: ApplicationFiled: January 30, 2013Publication date: August 1, 2013Applicant: Fresenius Kabi Deutschland GmbHInventor: Fresenius Kabi Deutschland GmbH
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Publication number: 20130184237Abstract: The present invention relates to nitric oxide delivering hydroxyalkyl starch derivatives, methods of preparing the same, and specific uses of these hydroxyalkyl starch derivatives.Type: ApplicationFiled: July 11, 2011Publication date: July 18, 2013Applicant: FRESENIUS KABI DEUTSCHLAND GMBHInventors: Martin Schimmel, Dominik Heckmann, Cornelius Jungheinrich
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Publication number: 20130171093Abstract: A wound healing powder, comprising a sugar selected from the group consisting of one or more pharmaceutically acceptable monosaccharides and disaccharides, in an amount of at least 25% by weight of the powder mixture; and an absorbent agent which forms a bioabsorbable biocompatible matrix with wound secretions, comprising a polymer formed of one or more of saccharide or saccharide derivative monomers and lactic acid monomers, in an amount of at least 25% by weight of the powder mixture.Type: ApplicationFiled: August 28, 2012Publication date: July 4, 2013Inventor: Philip A. Marraccini
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Patent number: 8470802Abstract: Sensory modifiers and compositions comprising sensory modifiers are described. The sensory modifiers comprise polysaccharide carbohydrate having at least about 75% by weight amylopectin and the polysaccharide carbohydrate has been treated and swollen with a substantially anhydrous solvent.Type: GrantFiled: October 8, 2008Date of Patent: June 25, 2013Assignee: Conopco, Inc.Inventor: Jack Polonka
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Patent number: 8470366Abstract: The present invention relates to soft pastilles for nicotine replacement therapy, said pastille comprises about 0.05% to about 1% of nicotine active; about 5% to about 40% of gelling agent; about 30% to about 70% of plasticizer; about 0.05% to about 10% of sweetener; 0.5% to about 30% of releasing agent; about 0.05% to about 2% of preservative; about 0.01% to 5% of flavoring agent; and about 5% to about 20% of water.Type: GrantFiled: February 17, 2011Date of Patent: June 25, 2013Inventor: Jatin Thakkar
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Patent number: 8466277Abstract: The invention relates to a method for coupling low-molecular weight substances to a starch-derived modified polysaccharide. The binding interaction between the modified polysaccharide and the low-molecular weight substance is based on a covalent bond which is the result of a coupling reaction between the terminal aldehyde group or a functional group of the modified polysaccharide molecule resulting from the chemical reaction of this aldehyde group and a functional group of the low-molecular weight substance which reacts with this aldehyde group or with the resulting functional group of the polysaccharide molecule. The bond directly resulting from the coupling reaction can be optionally modified by a further reaction to the aforementioned covalent bond. The invention further relates to pharmaceutical compositions that comprise conjugates formed in this coupling process and to the use of said conjugates and compositions for the prophylaxis or therapy of the human or animal body.Type: GrantFiled: February 28, 2003Date of Patent: June 18, 2013Assignee: Fresenius Kabi Deutschland GmbHInventors: Michele Orlando, Jurgen Hemberger, Klaus Sommermeyer, Wolfram Eichner, Sven Frie, Katharina Lutterbeck, Cornelius Jungheinrich, Roland Scharpf
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Patent number: 8445460Abstract: The invention relates to soluble, highly branched glucose polymers which are obtained by enzymatic treatment of starch, having a reducing sugars content of less than 3.5%, exhibiting a proportion of ?-1,6-glucosidic linkages of between 20% and 30%, a Mw, determined by light scattering, of between 20·103 and 30·103 daltons, and an osmolality of less than 25 mOsm/kg. The invention likewise relates to a method of obtaining these polymers and to their use in the pharmaceutical and food industries, more particularly in the field of enteral and parenteral nutrition, and in the field of peritoneal dialysis.Type: GrantFiled: February 15, 2007Date of Patent: May 21, 2013Assignee: Roquette FreresInventors: Laëtitia Deremaux, Carole Petitjean, Daniel Wills
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Publication number: 20130122063Abstract: A method of uncoupling mitochondria in a subject including administering nanotubes to the subject in a therapeutically effective amount, wherein the nanotubes are self-rectifying is provided. A method of decreasing reactive oxygen species and decreasing detrimental loading of Ca2+ into mitochondria is provided, including administering a pharmaceutically effective amount of nanotubes into the subject. A method of reducing weight, treating cancer, reducing the effects of traumatic brain injury, or reducing the effects of ageing, in a subject including administering a pharmaceutically effective amount of nanotubes into the subject is also provided.Type: ApplicationFiled: December 18, 2012Publication date: May 16, 2013Applicant: University of Kentucky Research FoundationInventor: University of Kentucky Research Foundation
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Publication number: 20130123213Abstract: A modified starch material for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.Type: ApplicationFiled: January 11, 2013Publication date: May 16, 2013Inventor: Xin Ji
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Patent number: 8440227Abstract: A biological adhesive formulation comprising dextrin, at least one adhesiveness modifier agent, and at least one antibiotic is suitable for promoting healing of tissue in a patient, for example, to prevent anastomosis of a surgical wound in the digestive system of a patient, and for affixing prosthesis during a hernia operation in a patient and occluding a fistula within a patient.Type: GrantFiled: April 23, 2012Date of Patent: May 14, 2013Inventor: Jorge Cueto-Garcia
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Publication number: 20130029934Abstract: The present invention relates to novel silyl-derivatives of polysaccharides and their salts, the processes for their preparation and their use in cosmetic/pharmaceutical field.Type: ApplicationFiled: March 4, 2011Publication date: January 31, 2013Inventors: Gaspare Aita, Demetrio Manenti, Pasqualino Rossi, Giuseppe Rosano
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Publication number: 20130029935Abstract: This document provides complexes comprising a mineral-amino acid compound and a polysaccharide. For example, the document provides compositions containing such complexes and methods of making and using such complexes.Type: ApplicationFiled: September 21, 2012Publication date: January 31, 2013Inventors: Alexander B. Rabovsky, Jeremy Ivie
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Publication number: 20130022636Abstract: A physical mode of action pesticide for application on plants and in soils, and methods of manufacture and application, comprising an active ingredient in the form of a polymer in a concentration of less than 0.1% wt., a surfactant, a co-solvent and a diluent in a hydrocolloid suspension. The suspension polymer is preferably a polysaccharide having a molecular weight of 10,000 to 25,000,000, and preferably in the range of about 600,000. The pesticide preferably also includes a targeting ingredient for directing the active ingredient to a particular target.Type: ApplicationFiled: September 27, 2012Publication date: January 24, 2013Applicant: CAI PATENT HOLDING, LLCInventors: Brook Chandler Murphy, Todd C. Steckler
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Publication number: 20130017231Abstract: The invention relates to a composition for forming a temporary intestinal occlusion in a mammal, said composition being flowable and solidifiable to form a solid plug at a predetermined site in the intestine, the structure of said plug being changeable to allow for a subsequent, at least partial removal of the occlusion, said composition being or comprising a flowable solution, suspension, or dispersion in a solvent or mixed solvent, characterized in that said composition comprises the following: a) a suspension of a solid in water or an aqueous mixed solvent, the suspension having a water content which exceeds the flow limit of the suspension by an amount X; b) a dehydrating agent in an amount which is sufficient to bind the amount X of water, so that, as a consequence of dehydration, the flow limit of the suspension is exceeded; and c) a means for passivating said dehydrating agent.Type: ApplicationFiled: July 12, 2012Publication date: January 17, 2013Inventor: Georg Bischof
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Publication number: 20130011364Abstract: The present invention relates to polymers imprinted by retention solutes, use of same as well as compositions containing same.Type: ApplicationFiled: March 18, 2011Publication date: January 10, 2013Inventors: Thomas Fichert, Ingo Bichlmaier
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Publication number: 20130005685Abstract: The invention relates to a compound, comprising a) a first starch derivative selected from the group consisting of hydroxyalkyl starch, carboxyl alkyl starch, ester starch and arbitrary mixtures thereof, wherein the starch derivative has a mean relative molar mass Mw1 and a degree of molar substitution MS1, and b) a second starch derivative selected from the group consisting of hydroxyalkyl starch, carboxyl alkyl starch, ester starch and arbitrary mixtures thereof, having a mean relative molar mass Mw2 and a degree of molar substitution MS2, characterized in that Mw1 is greater than Mw2 (Mw1>Mw2) and MS2 is greater than MS1 (MS2>MS1).Type: ApplicationFiled: December 6, 2010Publication date: January 3, 2013Applicant: B.Braun Melsungen AGInventors: Bernd Meier, Iris Theresia Jankowiak-Meier, Nele Meier, Clara Meier
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Publication number: 20120295873Abstract: The invention relates to branched soluble glucose polymers made of starch having an amylose content of at least 30 wt %, preferably 35 wt % to 80 wt %, having a glycosidic linkage ?-1,6 content of 7% to 10%, preferably 8% to 9%, and a MW of 50,000 to 150,000 daltons, characterized in that the polymers are resistant to pancreatic alpha amylase, expressed according to a test “B” for a reducing sugar content of 25% to 35%, and a MW of released products of 6,000 to 12,000 daltons.Type: ApplicationFiled: February 1, 2011Publication date: November 22, 2012Applicant: ROQUETTE FRERESInventors: Laetitia Guerin-Deremaux, Carole Petitjean, Daniel Wils
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Patent number: 8298559Abstract: A physical mode of action pesticide for application on plants and in soils, and methods of manufacture and application, comprising an active ingredient in the form of a polymer in a concentration of less than 0.1% wt., a surfactant, a co-solvent and a diluent in a hydrocolloid suspension. The suspension polymer is preferably a polysaccharide having a molecular weight of 10,000 to 25,000,000, and preferably in the range of about 600,000. The pesticide preferably also includes a targeting ingredient for directing the active ingredient to a particular target.Type: GrantFiled: July 9, 2009Date of Patent: October 30, 2012Inventors: Brook Chandler Murphy, Todd C. Steckler
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Publication number: 20120263667Abstract: The present invention relates to the use of benzoic acid and/or its sodium salt in combination with saccharide(s) as active components in the manufacture of a vaginal composition for modulating vaginal flora and vaginal acidity, thereby maintaining the pH value of vaginal secretion within a range from 3.5 to 4.5; and the present invention further relates to a vaginal composition and a method for modulating and maintaining normal vaginal flora and vaginal acidity.Type: ApplicationFiled: June 29, 2012Publication date: October 18, 2012Applicants: HK PHLORA HEALTH SCI. & TECH. LIMITED, SHENZHEN PHLORA BIOTECHNOLOGY LIMITEDInventors: Ruyun ZHOU, Zhongming ZENG
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Publication number: 20120253298Abstract: A tissue thickness compensator may generally comprise a first layer comprising a first medicament, a second layer comprising a second medicament, and a third layer comprising a third medicament. The tissue thickness compensator may comprise a first layer comprising a first medicament, a second layer comprising a second medicament, and a reservoir comprising a third medicament disposed within the reservoir. The medicaments may be independently selected from a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a pharmaceutically active agent, a matrix metalloproteinase inhibitor, and combinations thereof. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.Type: ApplicationFiled: March 28, 2012Publication date: October 4, 2012Applicant: Ethicon Endo-Surgery, Inc.Inventors: Cortney E. Henderson, Taylor W. Aronhalt, Chunlin Yang, Charles J. Scheib, Venkataramanan Mandakolathur Vasudevan, Mark D. Timmer, Richard W. Timm, Tamara Widenhouse, Steven G. Hall
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Publication number: 20120245123Abstract: Disclosed are methods for improving bone health, strength and formation in an infant who may be susceptible to developing bone health issues from conception through adolescence. The methods include administration of a nutritional formulation including a prebiotic to a woman during pregnancy and optionally during lactation and breastfeeding of an infant.Type: ApplicationFiled: March 20, 2012Publication date: September 27, 2012Applicant: ABBOTT LABORATORIESInventors: Jose Maria Lopez Pedrosa, Manuel Manzano Martin, Ricardo Rueda Cabrera
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Patent number: 8273378Abstract: Dialysis solutions comprising pyrophosphates and methods of making and using the dialysis solutions are provided. In an embodiment, the present disclosure provides a dialysis solution comprising a stable and therapeutically effective amount of pyrophosphate. The dialysis solution can be sterilized, for example, using a technique such as autoclave, steam, high pressure, ultra-violet, filtration or combination thereof. The dialysis solution can be in the form of a concentrate.Type: GrantFiled: January 14, 2010Date of Patent: September 25, 2012Assignees: Baxter International, Inc., Baxter Healthcare S.A.Inventors: Bruce L. Riser, Paul Zieske, Sujatha Karoor, Himanshu D. Patel
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Publication number: 20120238525Abstract: Peritoneal dialysis solutions including a glucose polymer and methods of using the dialysis solutions are disclosed herein. In a general embodiment, the peritoneal dialysis solution includes a glucose polymer in an amount to provide an increased ultrafiltration fluid volume for a given amount of carbohydrate absorbed compared to conventional dialysis solutions containing icodextrin as the active pharmaceutical ingredient. The increased ultrafiltration fluid volume for a given amount of carbohydrate absorbed is obtained by providing specific combinations of weight-average molecular weight, polydispersity index and concentration of the glucose polymer in the dialysis solution.Type: ApplicationFiled: March 14, 2012Publication date: September 20, 2012Applicants: BAXTER HEALTHCARE S.A., BAXTER INTERNATIONAL INC.Inventors: John Kenneth Leypoldt, Clifford J. Holmes, Sujatha Karoor, Catherine M. Hoff, Leo Martis, Rahul Tandon
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Patent number: 8263564Abstract: The invention provides an iron-carbohydrate complex compound which is characterized by a content of iron(II). The invention also provides processes for the preparation of the iron-carbohydrate complex compound and the use thereof for treatment of iron deficiency anaemias.Type: GrantFiled: January 15, 2008Date of Patent: September 11, 2012Assignee: Vifor (International) AGInventors: Stefan Reim, Peter Geisser
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Patent number: 8252333Abstract: A biological adhesive formulation comprising dextrin, at least one adhesiveness modifier agent, and at least one antibiotic is suitable for promoting healing of tissue in a patient, for example, to prevent anastomosis of a surgical wound in the digestive system of a patient, and for affixing a prosthesis during a hernia operation.Type: GrantFiled: August 22, 2006Date of Patent: August 28, 2012Inventor: Jorge Cueto-Garcia
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Patent number: 8242097Abstract: The present disclosure relates to the cosmetic use of grafted polysaccharide compounds comprising at least one non-polymer siloxane graft that may be obtained by reacting a polysaccharide and a siloxane compound corresponding to formula (I), such as for the cosmetic treatment of keratin materials. The disclosure also relates to compositions comprising the grafted polysaccharide compounds in a cosmetically acceptable medium, and also to certain novel grafted polysaccharide compounds comprising at least one non-polymer siloxane graft.Type: GrantFiled: August 18, 2005Date of Patent: August 14, 2012Assignee: L'Oreal S.A.Inventor: Michel Philippe
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Publication number: 20120177600Abstract: A composition capable of attenuating platelet hyperactivation and associated methods for administering the same to a subject, the composition comprising an aqueous solution containing from about 0.1% to about 7.0% by weight of a glycosaminoglycan and from about 1.0% to about 32% by weight of a neutral polysaccharide.Type: ApplicationFiled: September 21, 2010Publication date: July 12, 2012Inventors: Peter Byron Buckley, Konrad Messmer, Mark William Phillips
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Patent number: 8211483Abstract: The present invention relates to a composition comprising a starch or total dietary fiber which improves the cell viability, specifically, the inventive starch and total dietary fiber isolated from the extract of Gramineae plant and the components therefrom improved the cell viability when the cells were incubated under hypoxic condition, or in the presence of beta-amyloid and 6-hydroxydopamine treatment, as well as prevented and treated myocardiac infarction, cerebral infarction and vascular dementia, or alleviated memory loss, all of which were proven using rats as the respective animal models. Therefore, they can be used as therapeutics or health care food for preventing and treating ischemic diseases or degenerative brain diseases.Type: GrantFiled: July 4, 2008Date of Patent: July 3, 2012Assignees: Hypoxi Co., Ltd., Sun Mok Institute Education FoundationInventors: Jong Won Lee, Yae Sil Kim, Kyung Sik Song, Hyung Soo Han, Jung Hee Jang, Chae Ha Yang, Sun Ha Lim
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Publication number: 20120148523Abstract: A hydrogel tissue adhesive formed by reacting an aldehyde-functionalized polysaccharide containing pendant aldehyde groups with a water-dispersible, multi-arm amine is described. The hydrogel may be useful as a tissue adhesive or sealant for medical applications that require a more rapid degradation time, such as the prevention of undesired tissue-to tissue adhesions resulting from trauma or surgery.Type: ApplicationFiled: June 30, 2010Publication date: June 14, 2012Applicant: Actamax Surgical Materials LLCInventors: Helen S.M. Lu, Steven W. Shuey
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Publication number: 20120129805Abstract: The invention provides barley gain comprising a reduced level or activity of starch synthase IIa protein and a starch content of at least 41% (w/w) and methods of producing, identifying and using same. The grain may comprise an amylase content of at least 50%, a ?-glucan content of 5-9% (w/w) or greater than 9% (w/w), and/or a fructan content of 3-11% (w/w). The fructan may comprise a degree of polymerization from about 3 to about 12. For example, the plant and grain comprises a sex6-292 allele and/or an amo1 mutation. A food or beverage product, and methods of producing a food or beverage product, comprising obtaining or producing the subject grain and processing the grain to produce the product. Also contemplated are methods of improving one or more indicators of health in a mammal comprising administering a composition comprising the subject barley grain or a product comprising same.Type: ApplicationFiled: July 30, 2010Publication date: May 24, 2012Inventors: Zhongyi Li, Matthew Kennedy Morell
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Publication number: 20120114724Abstract: The present disclosure is directed to method of preparing an antimicrobial agent comprising heating a dialdehyde polysaccharide. The method comprises subjecting a dialdehyde polysaccharide, such as a dialdehyde starch or a dialdehyde cellulose, to heating and/or sonication for a period of time. Also provided herein is an antimicrobial composition comprising the prepared dialdehyde polysaccharide. The antimicrobial composition is effective at killing microbial agents such as viruses and bacteria within a short period of time.Type: ApplicationFiled: November 8, 2010Publication date: May 10, 2012Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.Inventors: Ronald Howard Baney, Samuel Ralph Farrah, Le Song
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Publication number: 20120116215Abstract: A method for treating a site within a patient from which tissue has been removed includes providing at least one press-formed marker body formed of polysaccharide and a suitable binder; and placing the at least one of the press-formed marker body within the site where tissue has been removed so as to provide hemostasis therein.Type: ApplicationFiled: November 21, 2011Publication date: May 10, 2012Inventors: Michael L. Jones, Paul Lubock
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Publication number: 20120083466Abstract: Provided herein are methods of treating, suppressing, inhibiting, or preventing allergic rhinitis in a subject comprising the step of administering to a subject a compound comprising a lipid or phospholipid moiety bond to a physiologically acceptable monomer, dimer, oligomer, or polymer, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof.Type: ApplicationFiled: December 12, 2011Publication date: April 5, 2012Inventor: Saul YEDGAR
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Publication number: 20120065160Abstract: A delivery system for use in the oral cavity, the system comprising a carrier for a bioactive substance. The carrier has a surface comprising oxygen-binding sites (X), and at least one link comprising a pentose group and one or more additional sugar groups, the pentose group being bonded to one of said oxygen binding sites (X) and wherein one or more bioactive molecules (R) are bonded directly to one of the sugar groups of the at least one link or to one or more substituents on one or more sugar groups in the at least one link.Type: ApplicationFiled: December 21, 2009Publication date: March 15, 2012Applicant: NEOINVENT MEDICAL ENGINEERING ABInventor: Jonatan Moses
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Publication number: 20120058173Abstract: The present invention includes a method for improving milk production in a ruminant. An amount of ruminally digestible starch in relation to the dry matter of a feed is manipulated to include a first selected ratio of ruminally digestible starch in relation to the dry matter of the feed which is fed to the ruminant during a first time interval after parturition. After the first time interval, the amount of ruminally digestible starch component in the dry matter of the feed is adjusted to a second ratio, lower than the first ratio, and fed to the ruminant.Type: ApplicationFiled: July 29, 2011Publication date: March 8, 2012Applicant: PURINA MILLS, LLCInventors: David C. Weakley, Kent J. Lanter, Lawrence F. Reutzel
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Publication number: 20120046235Abstract: Conjugates of an active substance and hydroxyalkyl starch (HAS) are provided herein. The active substance and the HAS are linked by a chemical moiety having a structure according to formula (I) wherein Y is O or S, and X is SH or (F). The conjugate has a structure according to formula (IV) wherein HAS? is a residue of HAS or a derivative thereof linked to the thioester group, and AS? is a residue of the active substance or derivative thereof linked to the alpha-X beta-amino group; or a structure according to formula (V) wherein HAS? is a residue of HAS or derivative thereof linked to the alpha-X beta-amino group, and AS? is a residue of the active substance or derivative thereof linked to the thioester group, and wherein the group —(C?Y) is derived from the thioester group —(C?Y)—S—R? and the group HN—CH—CH2—X is derived from the alpha-X beta amino group.Type: ApplicationFiled: September 8, 2006Publication date: February 23, 2012Inventors: Nobert Zander, Ronald Frank
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Patent number: 8114855Abstract: Low density cosmetic formulations which comprise: (a) a cosmetic mixture; and (b) a gas incorporated in the cosmetic mixture; wherein the cosmetic mixture comprises (i) an alk(en)ylpolyglycoside, (ii) a quaternary ammonium polymer, and (iii) a thickener, are described along with suitable cosmetic mixtures for forming such low density formulations, methods of forming such formulations and methods of treating skin, hair, nails and/or combinations thereof by contacting the skin, hair and/or nails with such formulations and/or products containing such formulations.Type: GrantFiled: November 21, 2007Date of Patent: February 14, 2012Assignee: L'OrealInventors: Jim M. Singer, Jolene A. Morris
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Publication number: 20120035129Abstract: A hydrogel tissue adhesive having decreased degradation time is described. The hydrogel tissue adhesive is formed by reacting an oxidized polysaccharide with a water-dispersible, multi-arm polyether amine in the presence of an oligomer additive, which promotes the degradation of the hydrogel. The hydrogel may be useful as a tissue adhesive or sealant for medical applications, such as a hemostat sealant or to prevent undesired tissue-to-tissue adhesions resulting from trauma or surgery.Type: ApplicationFiled: April 9, 2010Publication date: February 9, 2012Applicant: ACTAMAX SURGICAL MATERIALS LLCInventor: Mark E. Wagman
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Publication number: 20120034311Abstract: The present invention is directed towards various topical protective formulations which may be used as an adjunct in preventing the spread of a broad range of sexually transmitted diseases. The product is intended to be used as a topical lotion, cream, emulsion, or the like. The film forming excipients and active ingredients in the following formulations have demonstrated unique skin protective barrier properties with enhanced persistence that inhibits transmission of sexually transmitted diseases.Type: ApplicationFiled: October 17, 2011Publication date: February 9, 2012Applicant: CLJI I.P. COMPANY, LLCInventors: Craig LICHTBLAU, Jose I. IPARRAGUIRRE
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Publication number: 20120015039Abstract: Nutritional compositions delivered in vivo in a time controlled manner sustainable over long periods of time, provide enhancing athletic performance, increased hand/eye coordination and concentration on the task at hand.Type: ApplicationFiled: December 17, 2009Publication date: January 19, 2012Applicant: New World Pharmaceuticals, LLCInventors: Frederick A. Sexton, Sitaraman Krishnan, Venkat Kalyan Vendra
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Patent number: 8076279Abstract: The present invention is related to the use of a non-cellulosic cationically modified polysaccharide in cleaning compositions and more particularly to a surfactant based cleansing composition comprising, a surfactant, a non-cellulosic cationically modified polysaccharide and a solvent for use in personal care composition, household care composition or an institutional care composition.Type: GrantFiled: October 9, 2009Date of Patent: December 13, 2011Assignee: Hercules IncorporatedInventors: Piet Brand, Richard G. Brown, Anita N. Chan, Paquita Erazo-Majewicz, Jashawant J. Modi
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Patent number: 8071572Abstract: The present invention relates to a preventive/remedy for obesity, which has a hydroxypropylated starch as its active ingredient. Provided are materials for foods, drugs, etc. which can exhibit an effect of preventing/lessening the onset of various lifestyle related diseases, for example, an effect of preventing/ameliorating obesity, or preventing/ameliorating hyperlipidemia; have a high safety and a wide application range; and rarely damage their texture.Type: GrantFiled: March 8, 2004Date of Patent: December 6, 2011Assignee: Kao CorporationInventors: Akira Shimotoyodome, Junko Suzuki, Noriyuki Yajima, Takatoshi Murase, Ichirou Tokimitsu
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Publication number: 20110257090Abstract: The invention relates to artificial plasma-like solutions and methods for their use. The subject solutions find use in a variety of applications, particularly in those applications where at least a portion of a host's blood volume is replaced with a blood substitute.Type: ApplicationFiled: December 18, 2009Publication date: October 20, 2011Applicant: FRESENIUS KABI DEUTSCHLAND GMBHInventor: Norbet Breiter
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Publication number: 20110237542Abstract: The present invention relates to a composition for preventing tissue adhesion which comprising a bio-compatible hyaluronic acid and a polymer compound. More specifically, the invention is a composition containing hyaluronic acid which has not been modified by a chemical crosslinking or other chemical modification a method for preparing the same, and a composition for adhesion prevention with superior efficacy. The composition of the present invention for preventing adhesion exhibits a physical barrier function and a new adhesion prevention function whereby thrombus formation, which is the basis of adhesion, is inhibited.Type: ApplicationFiled: November 25, 2009Publication date: September 29, 2011Applicants: SHIN POONG PHARMACEUTICAL CO., LTD., POSTECH ACADEMY-INDUSTRY FOUNDATIONInventors: Il Hwan Cho, Sei Kwang Hahn, Eui Jin Hwang, Jang Sik Shin, Junseok Yeom
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Publication number: 20110224167Abstract: A skin-protecting alkalinity-controlling composition comprises one or more carboxylic acid polysaccharides. Said compositions are capable of providing buffering, and thus avoiding a major increase in the pH of an aqueous system and/or are capable of reducing the pH of aqueous systems, in which alkalinity is formed as a result of chemical and/or biological reactions. The compositions may be used in personal care products, such as skin creams and lotions, hygiene products, wound care products, fabric treating products etc.Type: ApplicationFiled: January 28, 2011Publication date: September 15, 2011Applicant: CP Kelco ApSInventor: Jens Eskil Trudsoe
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Publication number: 20110224724Abstract: A hydrogel tissue adhesive formed by reacting an aminated polysaccharide with a water-dispersible, aldehyde-functionalized multi-arm polyether is described. The hydrogel tissue adhesive may be useful as a general tissue adhesive and sealant for medical and veterinary applications such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, ophthalmic procedures, drug delivery, and to prevent post-surgical adhesions. Additionally, due to the presence of the aminated polysaccharide, the hydrogel tissue adhesive may also promote wound healing and blood coagulation, and provide antimicrobial properties.Type: ApplicationFiled: August 31, 2009Publication date: September 15, 2011Inventors: Helen S.M. Lu, Steven Willis Shuey
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Patent number: 8017739Abstract: Conjugates of hydroxyalkyl starch and a protein are provided herein. The conjugates are formed by a convalent linkage between the hydroxyalkyl starch or a derivative of the hydroxyalkyl starch and the protein. Methods of producing the conjugates and the use of the conjugates also are provided herein.Type: GrantFiled: September 8, 2006Date of Patent: September 13, 2011Assignee: Fresenius Kabi Deutschland GmbHInventors: Wolfram Eichner, Martin Schimmel, Frank Hacket, Elmar Kraus, Norbert Zander, Ronald Frank, Harald Conradt, Klaus Langer, Michele Orlando, Klaus Sommermeyer
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Publication number: 20110217249Abstract: The present invention provides compositions containing one or more antimicrobial peptide sequestering compounds and methods for topical application of such compositions to the skin to treat skin diseases and disorders such as rosacea in humans.Type: ApplicationFiled: March 2, 2011Publication date: September 8, 2011Inventor: Frank Dreher
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Publication number: 20110212916Abstract: A method and composition for improving one or more indicators of bowel health or metabolic health in a mammalian animal. This comprises the delivering to the gastrointestinal tract of the animal an effective amount of an altered wheat starch in the form of or derived from the grain of a wheat plant. The proportion of amylose in the starch of the grain is at least 30% and/or the grain comprises a reduced level of SBEIIa enzyme activity and/or protein relative to wild-type grain.Type: ApplicationFiled: April 16, 2010Publication date: September 1, 2011Inventors: Anthony Richard Bird, Gulay Saygat Mann, Sadequr Rahman, Ahmed Regina, Zhongyi Li, David Lloyd Topping, Matthew Kennedy Morell
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Publication number: 20110200670Abstract: The present invention relates to soft pastilles for nicotine replacement therapy, said pastille comprises about 0.05% to about 1% of nicotine active; about 5% to about 40% of gelling agent; about 30% to about 70% of plasticizer; about 0.05% to about 10% of sweetener; 0.5% to about 30% of releasing agent; about 0.05% to about 2% of preservative; about 0.01% to 5% of flavouring agent; and about 5% to about 20% of water.Type: ApplicationFiled: February 17, 2011Publication date: August 18, 2011Inventor: Jatin Thakkar