C Of C-o- Group Is Nuclear C Of A Benzene Ring (e.g., Phenol, Phenolate, Etc.) Patents (Class 514/731)
Polycyclo ring system (e.g., naphthols, etc.) (Class 514/732)
Acyclic carbon to carbon unsaturation (Class 514/733)
Two or more separate aryl-o-groups (Class 514/734)
Additional benzene ring containing (Class 514/736)
Nuclear halogenated (Class 514/737)
  • Horse liniment
    Patent number: 7811554
    Abstract: The horse liniment is a veterinary composition for topical application for the relief of muscle and joint pain in horses. The composition contains, by weight, about 49% alcohol, 20% olive oil, 10% arnica, 14% creosote, 1% iodine, 2% turpentine, 2% camphor, and 2% alum. The ingredients may be mixed at room temperature, the powdered ingredients being soluble in the alcohol-olive oil base. The composition is applied topically to the affected muscles or joints in conventional manner as needed. The composition has been found to be effective, often with a single application, with increased range of motion, an absence or reduction of limping, increased energy, and other signs of a healthy, active horse.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: October 12, 2010
    Inventor: Flavio Lozano
  • Therapeutic Compounds
    Publication number: 20100249246
    Abstract: A (?)-stereoisomer of formula (I): (formula I), wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, is useful as an anesthetic.
    Type: Application
    Filed: May 8, 2008
    Publication date: September 30, 2010
    Applicant: PharmacoFore, Inc.
    Inventor: Thomas E. Jenkins
  • Composition for preventing and/or treating bone disease, physiologically functional or health food containing thereof, and pharmaceutical containing thereof as active ingredients
    Patent number: 7803844
    Abstract: The present invention provides the pharmaceutical compositions, the pharmaceutical preparations thereof as an active ingredient, the health food, the food with health-promoting benefits and the like. The present invention provides the above-mentioned pharmaceutical preparations and the like comprising at least one of the compound shown in the following formula (I), physiologically acceptable salt thereof, or hydrate thereof. (wherein, R?1, R?2, and R?3 are independently a hydrogen atom, OH, or alkoxy group having C1 to C3, respectively. R1, R2, and R3 are independently a hydrogen atom or alkenyl group having C3 to C5, respectively).
    Type: Grant
    Filed: February 20, 2007
    Date of Patent: September 28, 2010
    Assignee: Erina Co. Inc.
    Inventors: Kun-Hyung Lee, Byung-Yoon Cha, Takayuki Yonezawa, Shinichi Hasegawa, Je-Tae Woo, Kazuo Nagai
  • NOVEL NUTRACEUTICALCOMPOSITIONS CONTAINING THYMOL AND/OR P-CYMENE OR PLANT EXTRACTS FOR COGNITION
    Publication number: 20100240768
    Abstract: The invention relates to a novel nutraceutical composition containing thymol and/or p-cymene, or a plant extract containing thymol or p-cymene as active ingredient(s). The compositions are useful for improvement of cognitive functions and psycho-social status, such as learning, memory and alertness, psychotic stability and maintenance.
    Type: Application
    Filed: October 17, 2008
    Publication date: September 23, 2010
    Inventors: Ann Fowler, Regina Goralczyk, Claus Kilpert, Annis Mayne-Mechan, Hasan Mohajeri, Bernd Mussler, Adrian Wyss
  • Caries Risk Test for Predicting and Assessing the Risk of Disease
    Publication number: 20100233185
    Abstract: Provided are methods, test devices, and diagnostic kits for predicting, assessing, and diagnosing the risk of a disease using salivary analysis. The methods comprise providing a whole (unfractionated) saliva sample from a subject; contacting an aliquot of the saliva with two or more lectins under conditions that allow the two or more lectins to bind to a lectin-binding component of the saliva; detecting the amount of bound lectin; and comparing the amount of bound lectin to the amount known to bind a saliva sample from a control patient, to predict the risk of a disease in the subject. Also provided are methods for reducing the risk of a disease and a method for assessing the risk of the disease at a defined level.
    Type: Application
    Filed: May 24, 2010
    Publication date: September 16, 2010
    Inventors: Patricia Denny, Paul C. Denny, Mahvash Navazesh
  • APOPTOSIS PROMOTERS
    Publication number: 20100234456
    Abstract: Compounds which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds and methods of treating diseases during which are expressed the Mcl-1 protein are disclosed.
    Type: Application
    Filed: May 25, 2010
    Publication date: September 16, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Michael D. Wendt, Hong Ding, Sheela A. Thomas, Steven W. Elmore, Wang Shen, Daniel A. Dickman, David Augeri
  • BEVERAGE CONTAINING A POLYMERIC POLYPHENOL
    Publication number: 20100222439
    Abstract: This invention relates to a polymeric polyphenol containing beverage, In particular it relates to a substantially clear ambient temperature beverage comprising tea solids derived from fermented tea. The invention also relates to a method for improving the clarity of a polymeric polyphenol containing liquid composition. It has long been observed that on cooling an aqueous black tea infusion from about 90 degrees Celsius to ambient temperature, a marked increase in the turbidity of the infusion can be seen leading ultimately to precipitation of up to about 30% w/w of the total tea solids. This precipitate is known as tea cream. It is thought that this precipitate originates from initial self-associations of polymeric polyphenols and association with caffeine thereby forming nano-clusters. These nano-clusters are not themselves responsible for any turbidity or precipitation of tea solids.
    Type: Application
    Filed: February 24, 2010
    Publication date: September 2, 2010
    Applicant: CONOPCO, INC., D/B/A UNILEVER
    Inventors: Haitao Chen, Weichang Liu, Dabin Xie
  • NOVEL MITOCHONDRIAL UNCOUPLING METHODS AND COMPOSITIONS FOR ENHANCING ADIPOCYTE THERMOGENESIS
    Publication number: 20100215782
    Abstract: Disclosed are methods, compounds, and compositions comprising botanically based drugs, medical foods, and dietary supplements for the prevention and treatment of metabolic disorders, in particular obesity, weight gain, insulin resistance syndromes, diabetes, fasting hyperlipidemia and osteoarthritis. More specifically, the invention relates to pharmaceutical therapeutic methods and compositions utilizing phytochemicals, natural plant extracts and combinations to modify adipocyte physiology to enhance thermogenesis and modify cytokine secretion.
    Type: Application
    Filed: October 20, 2009
    Publication date: August 26, 2010
    Applicant: METAPROTEOMICS, LLC
    Inventors: John G. Babish, Linda M. Pacioretty, Matthew L. Tripp, Jeffrey S. Bland
  • BOTANICAL EXTRACTS FROM OIL PALM VEGETATION LIQUOR FOR COSMECEUTICAL APPLICATIONS
    Publication number: 20100209544
    Abstract: A cosmeceutical composition comprising phenolic compounds, fruit acids and sugars. extracted from the vegetation liquor of the palm oil milling process has been suggested. This composition is rich in antioxidants, and significantly improves skin health, including preventing aging of the skin.
    Type: Application
    Filed: April 14, 2008
    Publication date: August 19, 2010
    Inventors: Ravigadevi Sambanthmurthi, Yew Ai Tan, Kalyana Sundram Manickam, Mohd Basri Bin Wahid
  • DEGLYCATION OF AGEs
    Publication number: 20100203175
    Abstract: The invention relates to the use, as an active ingredient, of at least one substance that promotes the deglycation of AGEs for preparing a composition, especially for limiting the presence of AGEs in a tissue. The invention particularly relates to the use of such a substance for preparing a composition intended to prevent and/or combat a reduction in flexibility and/or plasticity and/or elasticity and/or functionality of a tissue, and/or to prevent and/or combat the ageing of a tissue, by promoting the deglycation of AGEs in the tissue, said tissue preferably being the skin, or the tissue wall of a blood vessel or of an organ.
    Type: Application
    Filed: July 9, 2008
    Publication date: August 12, 2010
    Applicant: BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S.
    Inventors: Nabil ABDUL-MALAK, Cecile ALTOBELLI, Eric PERRIER
  • VISCOSE FIBER WITH MODIFIED PROPERTY AND A PROCESS FOR MAKING THEREFOR
    Publication number: 20100204289
    Abstract: A viscose fiber having property modifying constituents such as thermoregulatory activity, antimicrobial activity, and perfumed and a method of making thereof is disclosed. Micro-reservoirs are formed in the fibers having thermoregulatory activity, antimicrobial constituents, and perfumed constituents.
    Type: Application
    Filed: July 3, 2008
    Publication date: August 12, 2010
    Applicant: ADITYA BIRLA SCIENCE & TECHNOLOGY CO. LTD.
    Inventors: Preeti Lodha, Bir Kapoor, Tushar Mahajan
  • AGENTS FOR TREATMENT OF DIABETIC RETINOPATHY AND DRUSEN FORMATION IN MACULAR DEGENERATION
    Publication number: 20100204244
    Abstract: Agents that stimulate nuclear translocation of Nrf2 protein and the subsequent increases in gene products that detoxify and eliminate cytotoxic metabolites are provided in a method for treating diabetic retinopathy or drusen formation in age-related macular degeneration. The structurally diverse agents that act on the Nrf2/ARE pathway induce the expression of enzymes and proteins that possess chemically versatile cytoprotective properties and are a defense against toxic metabolites and xenobiotics. Agents include certain electrophiles and oxidants such as a Michael Addition acceptor, diphenol, thiocarbamate, quinone, 1,2-dithiole-3-thione, butylated hydroxyanisole, flavonoid other than genistein, an isothiocyanate, 3,5-di-tert-butyl-4-hydroxytoluene, ethoxyquin, a coumarin, combinations thereof, or a pharmacologically active derivative or analog thereof.
    Type: Application
    Filed: March 2, 2010
    Publication date: August 12, 2010
    Applicant: ALCON INC.
    Inventors: Robert A. Landers, David P. Bingaman
  • METHODS OF PREVENTING RESPIRATORY INFECTIONS
    Publication number: 20100203166
    Abstract: Methods for inhibiting the development of respiratory infections in humans are disclosed.
    Type: Application
    Filed: April 21, 2010
    Publication date: August 12, 2010
    Inventor: Saeed Rezakhany
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20100204312
    Abstract: This disclosure provides compositions and method useful for treating cell proliferative disorders including cancer. The disclosure provides cannabidiol derivatives and compositions thereof either alone or in combination with THC or a derivative thereof.
    Type: Application
    Filed: May 16, 2008
    Publication date: August 12, 2010
    Applicant: CALIFORNIA PACIFIC MEDICAL CENTER
    Inventors: Sean D. McAllister, Pierre-Yves Desprez
  • Microbicidal compositions including a cyanodithiocarbimate and a second microbicide, and methods of using the same
    Patent number: 7772156
    Abstract: Microbicidal compositions including (a) cyanodithiocarbimate and (b) an N-alkyl heterocyclic compound; a triazole compound or salt thereof or metal complex thereof; a microbicide with an activated halogen atom or a formaldehyde releasing compound; 1,4-bis(bromoacetoxy)-2-butene; 2-(thiocyanomethylthio)benzothiazole; a methylene-bis(thiocyanate); a halogenated acetophenone; a halopropynl compound; an iodosulfone; a phenol; a halocyanoacetamide compound and/or a quaternary ammonium compound are described. Components (a) and (b) can be present in a synergistically effective amount to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms with the compositions are also disclosed.
    Type: Grant
    Filed: November 1, 2006
    Date of Patent: August 10, 2010
    Assignee: Buckman Laboratories International, Inc.
    Inventor: Stephen D. Bryant
  • Pharmaceutical Formulation
    Publication number: 20100196488
    Abstract: The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments via mucosal surfaces, comprising: at least one lipophilic medicament, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation and the formulation is absent of a self emulsifying agent and/or a fluorinated propellant.
    Type: Application
    Filed: February 12, 2010
    Publication date: August 5, 2010
    Applicant: GW Pharma Limited
    Inventor: Brian Whittle
  • Regulation of Mammalian Keratinous Tissue Using Skin and/or Hair Care Actives
    Publication number: 20100189669
    Abstract: Personal care compositions containing an active selected from the group consisting of phlorogine, phlorgine BG, deoxyArbutin, sucrose dilaurate, bakuchiol, pyrenoine, millet, arlatone dioic acid, cinnamic acid, ferulic acid, achromaxyl, methyl nicotinamide, oil soluble licorice extract, folic acid, undecylenic acid, zinc undecylenate, L-tryptophan, thiamine HCl, hexylresorcinol, lipidami red vine, dragosine, methyl gentisate, inositol, symdiol 68, laminaine, their salts, their derivatives, their precursors, and/or combinations thereof. Methods for regulating the condition of mammalian keratinous tissue by topically applying the personal care compositions are also provided.
    Type: Application
    Filed: January 25, 2010
    Publication date: July 29, 2010
    Inventor: Tomohiro Hakozaki
  • APPLICATION OF 5-METHYL-1,3-BENZENEDIOL OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINES AND FUNCTIONAL FOODS FOR TREATMENT OR PREVENTION OF DEPRESSION
    Publication number: 20100190730
    Abstract: The present invention relates to the application of 5-methyl-1,3-benzenediol or its derivatives represented by Formula I; wherein the constituent variables are as defined herein or pharmaceutical compositions thereof containing them in the preparation of medicines or functional foods. The present studies indicate that 5-methyl-1,3-benzenediol or its derivatives represented by Formula I, wherein the constituent variables are as defined herein or pharmaceutical compositions thereof containing them show more significant antidepressant effects than fluoxetine or imipramine.
    Type: Application
    Filed: July 25, 2008
    Publication date: July 29, 2010
    Applicants: KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES, KUNMING INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES, KUNMING JINGBIAO BIOSCIENCES R&D CO., LTD.
    Inventors: Jijun Chen, Lin Xu, Jun Zhou, Jun Lu, Rongrong Mao, Meng Tian, Qixin Zhou, Xuemei Zhang, Yong Shen, Zhiyong Jiang, Aixue Zuo
  • Foamable Composition Containing Alcohol
    Publication number: 20100189611
    Abstract: This invention relates to compositions containing lower (C1-C4) alcohol and a polymeric fluorosurfactant formulated for being dispensed as a foam product. More particularly, the invention relates to improved compositions formulated with polymeric fluorosurfactants with pendant perfluoroalkyl side chains of a fully fluorinated chain length of C1-C7. The compositions also relate to use for personal care, such as skin sanitizing and cleansing.
    Type: Application
    Filed: April 2, 2010
    Publication date: July 29, 2010
    Applicant: The Clorox Company
    Inventors: David Lestage, David R. Scheuing, Scott L. Cumberland, Grant Templin
  • Foamable Compositions Containing Alcohol
    Publication number: 20100189809
    Abstract: This invention relates to compositions containing lower (C1-C4) alcohol and a polymeric fluorosurfactant formulated for being dispensed as a foam product. More particularly, the invention relates to improved compositions formulated with polymeric fluorosurfactants with pendant perfluoroalkyl side chains of a fully fluorinated chain length of C1-C7. The compositions also relate to use for personal care, such as skin sanitizing and cleansing.
    Type: Application
    Filed: April 2, 2010
    Publication date: July 29, 2010
    Applicant: The Clorox Company
    Inventors: David Lestage, David R. Scheuing, Scott L. Cumberland, Grant Templin
  • METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar
    Publication number: 20100190865
    Abstract: The invention provides in part dialkoxybenzene and eugenol compounds for controlling infestation by a Lymantria dispar, and methods thereof. The compounds include a compound of Formula I: where R1 may be methyl, ethyl, propyl, n-butyl, isopentyl (3-methylbutyl) or allyl; R2 may be at positions 2, 3 or 4 and may be H, methyl, ethyl, propyl, n-butyl, isopentyl (3-methylbutyl) or allyl; and R3 may be optionally present at positions 2, 3 and 4, and is allyl; with the provisos that when R2 is at position 2, R3 if present is at position 3, or when R2 is at to position 3, R3 if present is at positions 2 or 4, or when R2 is at position 4, R3 if present is at position 2; or of Formula II: where R1 may be methyl, ethyl, propyl, n-butyl, isopentyl (3-methylbutyl) or allyl; or mixtures thereof.
    Type: Application
    Filed: November 19, 2009
    Publication date: July 29, 2010
    Applicant: Simon Fraser University
    Inventors: Erika Plettner, Yongmei Gong, Regine Gries
  • Foamable Composition Containing Alcohol
    Publication number: 20100187263
    Abstract: This invention relates to compositions containing lower (C1-C4) alcohol and a polymeric fluorosurfactant formulated for being dispensed as a foam product. More particularly, the invention relates to improved compositions formulated with polymeric fluorosurfactants with pendant perfluoroalkyl side chains of a fully fluorinated chain length of C1-C7. The compositions also relate to use for personal care, such as skin sanitizing and cleansing.
    Type: Application
    Filed: April 2, 2010
    Publication date: July 29, 2010
    Applicant: The Clorox Company
    Inventors: David Lestage, David R. Scheuing, Scott L. Cumberland, Grant Templin
  • Method for reducing methane production emanating from the digestive activities of an animal
    Patent number: 7763273
    Abstract: The present invention generally relates to a method for reducing the production of methane emanating from the digestion of animal by using one or more essential oil compounds selected from the group consisting of limonene, eugenol, a silicylate, quinoline, vanilla, thymol and a cresol, which are administered to the animal feed.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: July 27, 2010
    Assignee: DSM IP Assets B.V.
    Inventor: Riccardo Losa
  • FORTIFICATION OF NUTRITIONAL PRODUCTS WITH OLIVE EXTRACTS CONTAINING HYDROXYTYROSOL AND HYDROXYTYROSOL FORTIFIED NUTRITIONAL PRODUCTS.
    Publication number: 20100184868
    Abstract: The present invention relates to nutritional products containing hydroxytyrosol, particularly fond products (i.e: fortified edible oils and fortified edible oil-containing products) and dietary supplements (i.e.: soft gel capsules containing fortified edible oils) with increased antioxidant capacity to be used as a source of hydroxytyrosol for preventing or treating cardiovascular diseases, plaque build-up in the arteries, arterial hypertension, and metabolic syndrome, thanks to the nutritional supply of an hydroxytyrosol rich composition.
    Type: Application
    Filed: July 23, 2008
    Publication date: July 22, 2010
    Inventors: Jose A. Lópes Más, Sergio A. Streitenberger, Marcos Peñalver Mellado, Pedro Martínez Ortiz
  • Compositions and methods for preventing or treating an inflammatory response
    Patent number: 7754769
    Abstract: The present invention relates to methods for modulating the inflammatory response of respiratory tract cells using an agent that increases ceramide levels in the cells of the respiratory tract.
    Type: Grant
    Filed: March 2, 2005
    Date of Patent: July 13, 2010
    Assignee: McGill University
    Inventors: Stan Kubow, Regina Maria Vilela, Larry Lands
  • 2,4,6-TRISUBSTITUTED PHENOLS HAVING ANESTHETIC PROPERTIES
    Publication number: 20100173997
    Abstract: Trisubstituted phenol compounds and methods of using the compounds, e.g., for anesthetizing a subject, are disclosed.
    Type: Application
    Filed: March 15, 2010
    Publication date: July 8, 2010
    Applicant: University of Iowa Research Foundatiion
    Inventor: Max T. Baker
  • METHOD AND MATERIAL FOR SITE ACTIVATED COMPLEXING OF BIOLOGIC MOLECULES
    Publication number: 20100158885
    Abstract: Methods of and compositions for producing and using plant-based materials are provided. The methods include using biopolymers or their synthetic equivalents combined with a stable source of reactive oxygen species that when applied to or combined with a separate source of oxido-reducing enzyme or catalyst will cause the formation of an activated biopolymer with increased protein binding affinity and microbial control activities.
    Type: Application
    Filed: March 1, 2010
    Publication date: June 24, 2010
    Applicant: METAACTIV, INC.
    Inventors: Alexander L. Huang, Gin Wu
  • Propofol Solution for Anesthetic Use
    Publication number: 20100160456
    Abstract: A transparent anesthetic solution for intravenous injection comprising at least 55% to 90% propofol dissolved in 10% to 45% of Macrogol 15 Hydroxystearate (SOLUTOL® HS 15), preferably having 25% by weight of Macrogol 15 Hydroxystearate (SOLUTOL® HS 15) for each 10.815 mg/ml of propofol. The solution may also include 0.0515 mg/ml of EDTA for each 10.815 mg/ml of propofol. The compositions result in decreased venous irritation and extends the shelf-life.
    Type: Application
    Filed: May 13, 2008
    Publication date: June 24, 2010
    Inventor: Ciriaco Quiroga
  • POLYMERIC MICELLAR CLUSTERS AND THEIR USES IN FORMULATING DRUGS
    Publication number: 20100159014
    Abstract: Polymeric micellar clusters formed from amphiphilic carbohydrate polymers and their uses in formulating drugs is disclosed, and in particular the finding that amphiphilic carbohydrate polymers are capable of self assembling to form micellar clusters in which the carbohydrate amphiphiles aggregate into hierarchically organised micellar clusters of individual aggregates. The micellar clusters may be transformed into stable nanoparticles with drugs, especially hydrophobic drugs that have poor aqueous solubility, and may improve the transfer of hydrophobic drugs across biological barriers.
    Type: Application
    Filed: August 8, 2007
    Publication date: June 24, 2010
    Inventors: Igeoma F. Uchegbu, Andreas G. Schatzlein, Xueliang Hou
  • PESTICIDAL METHODS AND COMPOSITIONS FOR MODULATING GABA RECEPTORS
    Publication number: 20100144888
    Abstract: Methods for using pesticidal compositions containing a pesticidally acceptable carrier, at least one GABA receptor modulator compound as a pesticidally active ingredient and optionally an additional compounds, such as a synergist, and methods for using same.
    Type: Application
    Filed: August 18, 2009
    Publication date: June 10, 2010
    Applicant: ECOSMART TECHNOLOGIES, INC.
    Inventor: Steven M. BESSETTE
  • TERPENE-CONTAINING COMPOSITIONS AND METHODS OF MAKING AND USING THEM
    Publication number: 20100136102
    Abstract: The present invention relates to compositions comprising terpenes and hollow glucan particles or cell wall particles and methods for preparing such compositions. The compositions increase terpene stability and activity and provide a suitable carrier for the terpenes. The invention also relates to methods of using such compositions,in the medical, veterinary and agricultural fields.
    Type: Application
    Filed: August 3, 2006
    Publication date: June 3, 2010
    Inventors: Lanny Franklin, Elizabeth Cloud, Lanna Knapp, Gary Ostroff, Gary Harman
  • USE OF HYDROXYTYROSOL AS ANTI-AGING AGENT
    Publication number: 20100130621
    Abstract: The present invention is directed to the use of (a composition comprising) hydroxytyrosol as anti-aging agent. The composition, to which the present invention is also directed, does essentially not comprise resveratrol and is administered orally to animals. The present invention is further directed to anti-aging methods. “Anti-aging” meaning in the context of the present invention: retarding the aging processes in said animals, improving age-related physiological deficits in said animals and/or promoting a healthy aging in said animals.
    Type: Application
    Filed: April 17, 2008
    Publication date: May 27, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Daniel Raederstorff, Ying Wang-Schmidt, Karin Wertz
  • USE OF COCOA EXTRACT
    Publication number: 20100130422
    Abstract: A cocoa extract obtainable by the extraction of non-defatted cocoa beans which have not been fermented or have been allowed to ferment for no more than three days, having a polyphenol content of more than 25% by weight, may be used in the treatment or alleviation of obesity.
    Type: Application
    Filed: April 24, 2008
    Publication date: May 27, 2010
    Inventors: Herwig Bernaert, Leen Allegaert
  • Parenteral Formulations Comprising Sugar-Based Esters and Ethers
    Publication number: 20100125051
    Abstract: The present invention relates to formulations for the parenteral administration of therapeutic agents, which contain sugar-based esters and ethers of fatty acids and fatty alcohols as surfactants. The formulations are advantageous for therapeutic agents which are insoluble or poorly soluble in water, and for reducing toxicity associated with common surfactants used in pharmaceutical formulations.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 20, 2010
    Applicant: BEN VENUE LABORATORIES, INC.
    Inventor: Douglas L. Brown
  • TOPICAL SKIN CARE COMPOSITION
    Publication number: 20100125057
    Abstract: A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.
    Type: Application
    Filed: January 22, 2010
    Publication date: May 20, 2010
    Applicant: GALDERMA S.A.
    Inventors: Nancy Puglia, Jerry Roth, Rosario Ramirez
  • PRESERVATIVE SYSTEM FOR COSMETIC FORMULATIONS
    Publication number: 20100120911
    Abstract: Disclosed is a novel method for preserving cosmetic/personal care formulations through a two component preservative system, said system comprising (a) Component I which functions to eliminate the existing microbial contamination load in a natural cosmetic formulation base through an optimized pasteurization method that avoids deep freezing; and (b) Component II that includes the step of adding synergistic blends of fractionated essential oils, extracts and isolated compounds to the pre-pasteurized cosmetic base obtained through the method of component I, wherein the synergistic blends sustain the effects of pasteurization through anti-microbial and anti-oxidant effects, said anti-oxidant effects enhancing further the anti-microbial effects by virtue of inhibiting lipid per oxidation that facilitates the undue proliferation of microbe.
    Type: Application
    Filed: May 4, 2009
    Publication date: May 13, 2010
    Inventors: Muhammed Majeed, Beena Bhat, Garima Agarwal
  • Compositions to reduce congestion and methods for application thereof to the nasal membrane
    Patent number: 7714011
    Abstract: A gelled composition formulated to maintain an active ingredient in association with the nasal membrane for an extended period of time is provided. The gelled composition may be formulated as a decongestant or a sinus discomfort relieving agent. The invention further includes a system and method for applying the gelled composition to the nasal membrane.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: May 11, 2010
    Assignee: Zicam, LLC
    Inventors: Tim Clarot, Charles Hensley
  • NOVEL USE OF HYDROXYTYROSOL
    Publication number: 20100113611
    Abstract: The invention relates to the use of hydroxytyrosol for inducing or enhancing cartilage repair or cartilage regeneration. Furthermore, the invention relates to nutraceutical and pharmaceutical compositions comprising hydroxytyrosol for regeneration and repair of cartilage injuries in joints, in particular of traumatic cartilage injuries.
    Type: Application
    Filed: April 3, 2008
    Publication date: May 6, 2010
    Inventors: Daniel Raederstorff, Joseph Schwager, Karin Wertz
  • Composition and Methods for the Protection of Hair From Treated Pool Water
    Publication number: 20100113588
    Abstract: Compositions for treating hair are disclosed. Methods of making and using compositions for treating hair are also disclosed.
    Type: Application
    Filed: October 29, 2009
    Publication date: May 6, 2010
    Inventor: S. Katharine Presty
  • Method of Treating Down Syndrome
    Publication number: 20100105756
    Abstract: The present invention relates to methods of treating of Down syndrome in a person using compounds of the invention.
    Type: Application
    Filed: November 24, 2009
    Publication date: April 29, 2010
    Applicant: AXONYX, Inc.
    Inventor: Gosse B. Bruinsma
  • Hydrofluoroalkyl phenols having anesthetic properties
    Patent number: 7705191
    Abstract: Substituted hydrofluoroalkylphenol compounds and methods of using the compounds, e.g., for anesthetizing a subject, are disclosed.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: April 27, 2010
    Assignee: University of Iowa Research Foundation
    Inventor: Max T. Baker
  • Pharmaceutical Anit-Infective Composition for Inhalation
    Publication number: 20100093650
    Abstract: A composition for inhalation, comprising at least: a) an effective amount of an antimicrobial aminoglycoside derivative or a salt thereof, and b) an effective amount of a biofilm modifier which is a macrolide derivative or a salt thereof.
    Type: Application
    Filed: October 11, 2007
    Publication date: April 15, 2010
    Applicant: LABORATORIES SMB S.A.
    Inventors: Philippe Baudier, Francis Vanderbist, Arthur Deboeck
  • Methods for treating glioblastoma with herbal compositions
    Publication number: 20100074977
    Abstract: The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric, Scutellaria baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1?, interleukin-1?, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.
    Type: Application
    Filed: November 20, 2009
    Publication date: March 25, 2010
    Applicants: NEW CHAPTER, INC., The Cleveland Clinic Foundation
    Inventors: Thomas Newmark, Mladen Golubic, Paul Schulick
  • COMPOSITION FOR PEST CONTROL
    Publication number: 20100069506
    Abstract: Compositions suitable for the control of pest amphibian species are described. More particularly, compositions for killing amphibians are described that comprise: (i) a xylenol compound or derivative according to formula (I) wherein R1, R2, R3, R4 and R5 are each independently selected from hydrogen, hydroxyl, halogen, —NH3 and C1-6 alkyl, and —R6—NH2, —R6—ONH2, —R6—NO2, and —R6—PO4, wherein R6 is C1-6 alkyl, and X is selected from hydrogen, halogen and C1-6 alkyl, or a salt thereof, and (ii) ethanol and optionally, (iii) methanol and/or at least one C3-6 alcohol. Methods for killing amphibians include contacting the amphibian with said compositions. Kits are described wherein said xylenol compounds and ethanol and optionally methanol and/or at least one C3-6 alcohol may be administered simultaneously or sequentially.
    Type: Application
    Filed: December 18, 2007
    Publication date: March 18, 2010
    Inventors: David James Dall, Joan Dawes
  • 2,4,6,-trisubstituted having anesthetic properties
    Patent number: 7678946
    Abstract: Trisubstituted phenol compounds and methods of using the compounds, e.g., for anesthetizing a subject, are disclosed.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: March 16, 2010
    Assignee: University of Iowa Research Foundation
    Inventor: Max T. Baker
  • FORMULATION OF NATURAL TRITERPENES AND BIOPHENOLS OBTAINED FROM THE GENUS OLEA IN LIPOSOMES
    Publication number: 20100055163
    Abstract: The present invention relates to compositions of natural biophenols and, optionally, of natural biophenols and triterpenes obtained from the genus Olea. The compositions comprise said biophenols and/or triterpenes included in liposomes. The preferred biophenols within the context of the invention are tyrosol and hydroxytyrosol and the preferred triterpenes are maslinic acid and oleanolic acid and/or their salts.
    Type: Application
    Filed: May 18, 2007
    Publication date: March 4, 2010
    Applicant: UNIVERSIDAD DE GRANADA
    Inventor: Andres Garcia-Granados Lopez De Hierro
  • Method of mediating Airway Smooth Muscle Construction Due to Airway Irritation
    Publication number: 20100048732
    Abstract: Methods of minimizing bronchospasm and contraction of airway smooth muscle due to irritation of the airway are provided. More particularly, a method is provided of mitigating bronchospasm or airway smooth muscle constriction due to irritation. This method includes administering to a subject in need of such treatment an amount of propofol or a derivative thereof effective to decrease the severity and/or duration of bronchospasm or airway smooth muscle constriction. Also provided are methods of up-regulating GABA mediated relaxation of airway smooth muscle at GABAA receptors expressed on airway smooth muscle and methods of anesthetizing a subject and minimizing bronchospasm or airway smooth muscle constriction due to irritation using propofol or a propofol derivative.
    Type: Application
    Filed: May 30, 2007
    Publication date: February 25, 2010
    Inventor: Charles W. Emala, SR.
  • STABLE AND READY-TO-USE OIL-IN-WATER PROPOFOL MICROEMULSION
    Publication number: 20100041769
    Abstract: The present invention describes a new propofol-containing anesthetic pharmaceutical composition for parenteral administration, in the form of an oil-in-water microemulsion in which the oily phase is constituted by propofol in the form of particles with size comprised between 1 and 100 nm using a single surfactant selected from the group consisting of polyethylene glycol stearates with general formula C17H35COO. (OCH2CH2)nH or C17H35COO. (OCH2CH2)n.COOC17H35. The anesthetic pharmaceutical composition of the present invention is more potent for induction of hypnosis and anesthesia, has a ready-to-use presentation and highly stable particle size, presenting improved physicochemical properties, and preventing the potential risks of undesirable effects encountered in the state-of-the-art propofol formulations.
    Type: Application
    Filed: October 23, 2007
    Publication date: February 18, 2010
    Inventors: Ogari Pacheco, Roberto Moreira, Marisa Rizzi
  • DISINFECTANT FORMULATION
    Publication number: 20100034907
    Abstract: An aqueous disinfectant formulation comprising at least one phenolic compound of natural origin; a surfactant sufficient to form a solution or dispersion of the essential oil in an aqueous carrier; a solvent, and sufficient water to make 100 weight percent is described herein.
    Type: Application
    Filed: April 8, 2009
    Publication date: February 11, 2010
    Applicant: Laboratoire M2
    Inventors: François Daigle, Ann Letellier, Sylvain Quessy
  • GRANULATE CONTAINING A PHARMACEUTICALLY ACTIVE SUBSTANCE AND METHOD FOR ITS MANUFACTURE
    Publication number: 20100034888
    Abstract: One aspect of the present invention relates to a granulate having a volume weighted mean diameter of 1-200 m and containing: at least 0.1 wt. % of a pharmaceutically active substance; at least 10 wt. % of emulsifier 0-89.9 wt. % of a water-dispersible saccharide; the combination of the pharmaceutically active substance, the emulsifier and the water-dispersible saccharide together representing at least 60 wt. % of the granulate; wherein the granulate is monophasic or wherein the granulate comprises a dispersed phase containing the pharmaceutically active substance, said dispersed phase having a volume weighted mean diameter of less than 300 nm. Another aspect of the invention relates to a process for the preparation of said granulate containing a pharmaceutically active substance, which process employs.
    Type: Application
    Filed: September 14, 2007
    Publication date: February 11, 2010
    Inventors: Hubert Clemens Pellikaan, Pieter Sebastlaan Vermeulen, Johannes Caspar Mathias Elizabeth Bender, Maria Vanesa Fernandez Cid