Abstract: An ophthalmic preparation and a method for preparing the ophthalmic preparation is described. The ophthalmic preparation has an enhanced ability to permit essentially normal maintenance of ocular surface mucus-containing goblet cells while present in the eye.

Abstract: Freeze-dried pharamceutical compositions of antitumor phenylquinoline carboxylic acids, such as 6-fluoro-2-(2'-fluoro-1'-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid, sodium salt, reconstitutable to stable, aqueous, injectable compositions are provided. These compositions use a stabilization system consisting essentially of bile salt, such as sodium cholate or sodium desoxycholate, and a base or buffer that will provide a pH of about 8.5-11 upon a aqueous reconstitution. Glycine is the preferred buffer.

Abstract: A solvent-free oil-in-water emulsion of propetamphos comprising(a) 5 to 50% by weight of technical propetamphos in the form of droplets having a particle size of below 5 micron,(b) 1 to 8% by weight of a polyvinyl alcohol,(c) 1 to 3% by weight of a buffer, buffering the pH of the formulation to pH 6 to 7,(d) 1 to 2% by weight of a vegetable oil,(e) 0.5 to 2% by weight of an emulsifier(f) 0 to 8% by weight of an antifreezing agent(g) 0 to 0.1% by weight of an antifoaming agent (h) 0 to 0.1% by weight of a perfume,the balance being water, and a process of preparing such emulsion.

Abstract: An ophthalmic preparation and a method for preparing the ophthalmic preparation is described. The ophthalmic preparation has an enhanced ability to permit essentially normal maintenance of ocular surface mucus-containing goblet cells while present in the eye.

Abstract: An ophthalmic solution for improving the exchange of fluid in the area outside a hydrogel contact lens with the fluid in the area underneath the hydrogel contact lens comprising:(a) 0.0005% by weight to an amount of a hydrogel contact lens flattening agent equivalent to 330 milliosmoles/kg;(b) an amount of a viscosity enhancing agent sufficient to cause the composition to have a Brookfield relative viscosity of 3 to 50 cps; and(c) an amount of an ionic salt sufficient to render the solution substantially isotonic.The invention also includes a method for improving the exchange of fluid in the area outside a hydrogel contact lens with the fluid in the area underneath the hydrogel contact lens in a human eye comprising adding to said eye an effective amount of such ophthalmic solutions.

Abstract: Free flowing, substantially dust-free, dense granular amorphous precipitated silica having a principal particle size of between about 0.14 millimeters and about 0.84 millimeters are described. This material is particularly suitable as an inert carrier for water-soluble and fat soluble nutritional supplements, e.g., vitamins, which are added to feeds for livestock.

Abstract: A device for the controlled release of an active material into an aqueous medium comprises a porous sintered body of a water soluble glass (11). The pores of the body are filled with a composition (12) consisting wholly or partially of an active material. The device may be provided with a low solubility coating (13). On immersion in an aqueous medium the glass (11) dissolves to become a sponge-like structure having a plurality of convoluted capillaries and from which the active material is released.

Abstract: A pest control device, such as an ear tag, for controlling pests such as flies, fleas and ticks on animals such as cattle and other livestock or pet animals which comprises a polymeric resin matrix and the pesticidally active compound .alpha.-cyano-3-phenoxybenzyl 2-(2-chloro-4-trifluoromethylanilino)-3-methylbutanoate.

Abstract: A cosmetically acceptable composition for topical application to human skin or hair in order to reduce greasiness comprises, at a concentration of from 0.0001M to 0.5M, a biotin antagonist which is capable of blocking the activity of the biotin dependent enzyme acetyl-SCoA-carboxylase implicated in sebum production; together with a carrier other than water as an aid to delivering the biotin antagonist to the sebaceous gland.