With Antiflatulent Patents (Class 514/820)
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Patent number: 6767559Abstract: The present invention provides DASC compositions, which upon introduction into aqueous solutions, form stable, non-gritty suspensions. The present invention also provides stable, non-gritty suspensions comprising the DASC compositions of the present invention admixed in aqueous solutions. In addition, the present invention provides processes for preparing the suspensions which comprise admixing the DASC compositions of the present invention with aqueous solutions. Finally, the present invention provides processes for preparing the DASC compositions of the present invention.Type: GrantFiled: July 15, 2002Date of Patent: July 27, 2004Assignee: Chattem Chemicals, Inc.Inventors: Joel Swinson, Richard D. Giles, Jack Pitkin, Glenda Fleming, David B. Blum
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Patent number: 6444232Abstract: The present invention provides DASC compositions, which upon introduction into aqueous solutions, form stable, non-gritty suspensions. The present invention also provides stable, non-gritty suspensions comprising the DASC compositions of the present invention admixed in aqueous solutions. In addition, the present invention provides processes for preparing the suspensions which comprise admixing the DASC compositions of the present invention with aqueous solutions. Finally, the present invention provides processes for preparing the DASC compositions of the present invention.Type: GrantFiled: June 23, 2000Date of Patent: September 3, 2002Assignee: Chattem Chemicals, Inc.Inventors: Joel Swinson, Richard D. Giles, Jack Pitkin, Glenda Fleming, David B. Blum
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Patent number: 6110506Abstract: The present invention provides DASC compositions, which upon introduction into aqueous solutions, form stable, non-gritty suspensions. The present invention also provides stable, non-gritty suspensions comprising the DASC compositions of the present invention admixed in aqueous solutions. In addition, the present invention provides processes for preparing the suspensions which comprise admixing the DASC compositions of the present invention with aqueous solutions. Finally, the present invention provides processes for preparing the DASC compositions of the present invention.Type: GrantFiled: December 30, 1999Date of Patent: August 29, 2000Assignee: Chattem Chemicals, Inc.Inventors: Joel Swinson, Richard D. Giles, Jack Pitkin, Glenda Fleming, David B. Blum
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Patent number: 6100245Abstract: The present invention provides compositions and methods for treating ulcerative colitis by providing an effective amount of simethicone and in a preferred embodiment in combination with sulfasalazine.Type: GrantFiled: September 7, 1999Date of Patent: August 8, 2000Assignee: McNeil-PPC, Inc.Inventor: Thomas Sox
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Patent number: 6048552Abstract: The present invention provides DASC compositions, which upon introduction into aqueous solutions, form stable, non-gritty suspensions. The present invention also provides stable, non-gritty suspensions comprising the DASC compositions of the present invention admixed in aqueous solutions. In addition, the present invention provides processes for preparing the suspensions which comprise admixing the DASC compositions of the present invention with aqueous solutions. Finally, the present invention provides processes for preparing the DASC compositions of the present invention.Type: GrantFiled: March 26, 1997Date of Patent: April 11, 2000Assignee: Chattem Chemicals, Inc.Inventors: Joel Swinson, Richard D. Giles, Jack Pitkin, Glenda Fleming, David B. Blum
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Patent number: 5914135Abstract: Calcium carbonate liquid antacid compositions containing one or more pH adjusting agents to maintain the pH above 9.0, preferably above 9.5. The resultant antacid liquid possesses superior resistance to microbial attack and enhanced taste properties.Type: GrantFiled: April 16, 1997Date of Patent: June 22, 1999Assignee: McNeil-PPC, Inc.Inventors: John J. Dubek, Gerard P. McNally, Bruce P. Smith
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Patent number: 5882671Abstract: The present invention provides a method of treating anxiety and related disorders using an agonist which acts at negatively coupled cAMP-linked metabotropic glutamate receptors.Type: GrantFiled: January 21, 1997Date of Patent: March 16, 1999Assignee: Eli Lilly and CompanyInventors: David Reed Helton, Mary Jeanne Kallman, James Allen Monn, Darryle Darwin Schoepp, Joseph Patrick Tizzano
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Patent number: 5641535Abstract: The invention relates to a process for the preparation of microencapsulated flakes or powders by drying aqueous mixtures containing (a) one or more water-emulsifiable, non-thermoplastic compounds which have a higher boiling point than water and (b) at least one water-soluble, film-forming polymer, in which the content of component (a) is up to about 95% by weight, based on the dry weight of components (a) and (b), with the proviso that the water-soluble, film-forming polymer has a flocculation point of from 20.degree. to 98.degree. C. or the flocculation point is adjusted to from 20.degree. to 98.degree. C. with the aid of additives, and drying is carried out by thin-layer drying in a temperature range above the flocculation point.Type: GrantFiled: February 26, 1992Date of Patent: June 24, 1997Assignee: Wacker-Chemie GmbHInventors: Herbert Eck, Heinrich Hopf, Gerald Fleischmann, Ernst Innertsberger, Jakob Schmidlkofer
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Patent number: 5612054Abstract: This invention relates to a pharmaceutical composition for treating gastrointestinal distress comprising an effective amount of an antidiarrheal composition, e.g. loperamide, and an antiflatulent effective amount of simethicone and methods of treating gastrointestinal distress comprising administering such pharmaceutical compositions.Type: GrantFiled: April 19, 1995Date of Patent: March 18, 1997Assignee: McNeil-PPC, Inc.Inventor: Jeffrey L. Garwin
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Patent number: 5560913Abstract: The present invention relates to orally ingestible, pharmaceutical compositions containing at least one pharmaceutical active and a taste masking component.Type: GrantFiled: January 27, 1995Date of Patent: October 1, 1996Assignee: The Procter & Gamble CompanyInventor: Philip L. Kupper
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Patent number: 5512629Abstract: Aqueous dispersions of polymers which have a high glass transition temperature and a low average molecular weight and contain a specific amount of methacrylic acid as polymerized units are suitable, in liquid or dried form, as additives for improving the flow behavior of cement-containing mineral building materials having binding properties.Type: GrantFiled: May 20, 1994Date of Patent: April 30, 1996Assignee: BASF AktiengesellschaftInventors: Wilhelm F. Beckerle, Rolf Petri, Bernhard Dotzauer, Manfred Schwartz, Maximilian Angel
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Patent number: 5458886Abstract: Free-flowing granular compositions principally for use in treatment of gastric disorders comprise (A) titanium dioxide having a particle size within the range from 10 nanometers to 60 nanometers and a specific BET (nitrogen) surface area of at least 30 m.sup.2 /g in combination with (B) an organopolysiloxane antifoam agent (for example a mixture of from 90 to 99 percent by weight of a polydiorganosiloxane and from 1 to 10 percent by weight of a finely-divided silica having a surface area to weight ratio of at least 50 m.sup.2 /g), (B) being present in a proportion of from 30 to 70 percent by weight calculated on the combined weight of (A) and (B). The compositions may contain from 40 to 60 percent of (B) based on the combined weight of (A) and (B). They may also contain an antacid or other medicament, glycerol, an effervescent agent and/or a disintegrant component.Type: GrantFiled: May 31, 1994Date of Patent: October 17, 1995Assignee: Dow Corning France S.A.Inventor: Francois J. Briquet
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Patent number: 5275822Abstract: A defoaming or antifoaming composition comprises a free flowing granular combinate of 50 to 90 weight percent of a water soluble carbohydrate-based agglomerate selected from the group consisting of maltodextrin agglomerates, maltodextrin/dextrose co-agglomerates, dextrose agglomerates, maltodextrin/sucrose co-agglomerates, maltodextrin/fructose co-agglomerates, sucrose agglomerates, fructose agglomerates, mannitol agglomerates, sorbitol agglomerates, agglomerates of hydrolyzed cereal solids, and agglomerates of corn syrup solids and about 10 to 50 weight percent of a liquid, nonaqueous, defoaming or antifoaming composition such as simethicone, hydrocarbon-based oils or silicone oils. The composition may be combined with one or more suitable excipients and prepared as a unit dosage in the form of a compressed tablet, filled capsule, packet, or granule for various defoaming applications.Type: GrantFiled: December 12, 1991Date of Patent: January 4, 1994Assignee: Valentine Enterprises, Inc.Inventors: William Valentine, William K. Valentine
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Patent number: 5248505Abstract: This invention relates to a pharmaceutical composition for treating gastrointestinal distress comprising an effective amount of an antidiarrheal composition, e.g. loperamide, and an antiflatulent effective amount of simethicone and methods of treating gastrointestinal distress comprising administering such pharmaceutical compositions.Type: GrantFiled: March 17, 1992Date of Patent: September 28, 1993Assignee: McNeil-PPC, Inc.Inventor: Jeffrey L. Garwin
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Patent number: 5244670Abstract: Ingestible pharmaceutical compositions comprising pharmaceutical actives useful for treating upper gastrointestinal tract distress (e.g., antacid agents) and 3-1-menthoxy propane 1,2-diol in amounts effective for providing a cooling sensation to the throat.Type: GrantFiled: May 20, 1992Date of Patent: September 14, 1993Assignee: The Procter & Gamble CompanyInventors: James G. Upson, Carmelita M. Russell
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Patent number: 5229137Abstract: Pharmaceutical medications and methods are disclosed for providing instant and sustained relief from pain or symptoms associated with episodic heartburn in humans. The medications consist essentially of antacids and histamine H.sub.2 -receptor antagonists, and may be administered on an as-needed basis in liquid or solid dosage forms. Typical antacids which may be used in combination with the histamine H.sub.2 -receptor antagonist are conventional antacids which are well known and widely used in the treatment of excess acid related gastrointestinal dysfunctions. Exemplary of typical antacids include, sodium bicarbonate, calcium carbonate, magnesium hydroxide and aluminum hydroxide, as well as commercially available high potency, flavored antacids. Histamine H.sub.2 -receptor antagonists which may be used in combination include those conventionally used in the treatment of peptic ulcers, such as, for example, cimetidine, ranitidine, famotidine and nizatidine.Type: GrantFiled: May 6, 1992Date of Patent: July 20, 1993Assignee: Brigham and Women's Hospital, Inc.Inventor: M. Michael Wolfe
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Patent number: 5068109Abstract: The present invention relates to an antacid composition with floating properties, and a method of treating or alleviating upper gastrointestinal dyspeptic disorders.Type: GrantFiled: December 5, 1989Date of Patent: November 26, 1991Assignee: Farma Food A/SInventors: Jorgen Foldager, Helle Toftkjor, Kim Kjornos
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Patent number: RE35893Abstract: A defoaming or antifoaming composition comprises a free flowing granular combinate of 50 to 90 weight percent of a water soluble carbohydrate-based agglomerate selected from the group consisting of maltodextrin agglomerates, maltodextrin/dextrose co-agglomerates, dextrose agglomerates, maltodextrin/sucrose co-agglomerates, maltodextrin/fructose co-agglomerates, sucrose agglomerates, fructose agglomerates, mannitol agglomerates, sorbitol agglomerates, agglomerates of hydrolyzed cereal solids, and agglomerates of corn syrup solids and about 10 to 50 weight percent of a liquid, nonaqueous, defoaming or antifoaming composition such as simethicone, hydrocarbon-based oils or silicone oils. The composition may be combined with one or more suitable excipients and prepared as a unit dosage in the form of a compressed tablet, filled capsule, packet, or granule for various defoaming applications.Type: GrantFiled: January 18, 1995Date of Patent: September 8, 1998Assignee: Valentine Enterprises, Inc.Inventors: William K. Valentine, William Valentine