Mouthwash Patents (Class 514/901)
-
Patent number: 5028412Abstract: Anti-calculus oral compositions include an aluminum salt and an aliphatic carboxylic acid or water-soluble salt thereof capable of complexing with the aluminum, together with a carrier suitable for use in the oral cavity. Such compositions exhibit marked effectiveness in inhibiting the formation and growth of calculus on the dental enamel.Type: GrantFiled: July 17, 1990Date of Patent: July 2, 1991Assignee: Purdue Research FoundationInventors: Mark S. Putt, Carl J. Kleber
-
Patent number: 5028415Abstract: The present invention relates to oral compositions, such as dentifrices, toothpastes and mouthwashes, which provide an anticalculus benefit. These compositions comprise a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salts, along with a pharmaceutically-acceptable carrier. The present invention also relates to a method for inhibiting or reducing the development of dental calculus by contacting the oral cavity with a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salt.Type: GrantFiled: December 16, 1988Date of Patent: July 2, 1991Assignee: The Procter & Gamble CompanyInventors: James J. Benedict, Rodney D. Bush, Richard J. Sunberg
-
Patent number: 5011830Abstract: The present invention relates to oral hygiene compositions having improved anticalculus activity containing a mixture of a sodium and potassium pyrophosphate salt and a polyacrylic acid or salt thereof or copolymers of acrylic acid and another monomer or mixtures thereof and an effective amount of a water soluble fluoride salt in a pharmaceutically acceptable carrier to provide enhanced anticalculus benefits.Type: GrantFiled: July 16, 1990Date of Patent: April 30, 1991Assignee: The Proctor & Gamble CompanyInventors: Giles J. Leonard, Michael L. Marberry
-
Patent number: 5004597Abstract: An oral hygiene compositions possessing antiplaque and antigingivitis properties containing stannous fluoride stabilized with stannous gluconate in an orally acceptable carrier at pH of from about 3.0% about 4.79 and said composition is substantially free of a calcium ion source.Type: GrantFiled: September 13, 1989Date of Patent: April 2, 1991Assignee: The Procter & Gamble CompanyInventors: Satyanarayana Majeti, Christopher B. Guay, Mark M. Crisanti
-
Patent number: 4994441Abstract: Adhesion of bacteria in the buccal cavity which are responsible for the formation of dental plaque and caries is inhibited by kappa-caseino-glycopeptide compounds and desialylated derivaties thereof contained in compositions having a form suitable for being empolyed for treating the bacteria in the buccal cavity.Type: GrantFiled: February 8, 1988Date of Patent: February 19, 1991Assignee: Nestec S.A.Inventor: Jean-Richard Neeser
-
Patent number: 4992420Abstract: Kappa-caseino-glycopeptide compounds and desialylated derivatives thereof and compositions containing the same are employed for treating bacteria in the buccal cavity which are responsible for the formation of dental plaque and caries.Type: GrantFiled: July 17, 1990Date of Patent: February 12, 1991Assignee: Nestec S.A.Inventor: Jean-Richard Neeser
-
Patent number: 4990329Abstract: The invention relates to an oral hygiene composition for treating or preventing anaerobe infections in humans and lower animals.Type: GrantFiled: November 3, 1988Date of Patent: February 5, 1991Assignee: The Procter & Gamble CompanyInventor: Padmini Sampathkumar
-
Patent number: 4981875Abstract: Etofenamate is used for the preparation of compositions useful in the treatment of bacterial, viral or fungicidal inflammations in the region of the oral cavity.Type: GrantFiled: July 22, 1988Date of Patent: January 1, 1991Assignee: Bayer AktiengesellschaftInventors: Bernd Leusner, Rudiger Heiss, Bernd Pelster, Wolfgang Fischer, Ulrich Ohm
-
Patent number: 4980150Abstract: A chlorhexidine complex is prepared by complexing chlorhexidine (a divalent, cationic antiseptic) with an anionic polymer such as algin or carboxymethylcellulose. The complex is insoluble but can be granulated or crushed to a fine powder. In powdered form the complex forms stable aqueous dispersions. The chlorhexidine complex is suitable for inclusion in oral hygiene compositions such as dentrifrices, and in other antibacterial compositions such as opthalmic under-eye-lid treatment capsules topical preparations and ocular solutions.Type: GrantFiled: April 27, 1989Date of Patent: December 25, 1990Assignee: Zetachron, Inc.Inventor: Alec D. Keith
-
Patent number: 4980153Abstract: An oral hygiene composition in the form of a dentifrice or a mouthwash, comprising: (a) from 0.01 to 2% by weight of the composition of an antibacterial compound of formula (I): ##STR1## in which R.sup.1 is oxygen, sulphur or an alkylene group of from 1 to 6 carbon atoms, each of R.sub.2 to R.sub.6 and R.sup.2 ' to R.sup.6 ' is hydrogen, hydroxyl or halogen; (b) from 0 to 90% by weight of a dentally acceptable abrasive, (c) from 0.1% to 15% by weight of a dialkali or tetra-alkali metal pyrophosphate salt or a mixture thereof and (d) water.Type: GrantFiled: March 15, 1989Date of Patent: December 25, 1990Assignee: Beecham Group p.l.c.Inventors: Robert J. Jackson, Nicholas A. Berrill, Shawn V. Robbins
-
Patent number: 4978522Abstract: Oral compositions effective against caries containing strontium EDTA and a soluble fluoride ion source are described herein.Type: GrantFiled: March 9, 1989Date of Patent: December 18, 1990Assignee: The Procter & Gamble CompanyInventors: Melvin A. Barbera, Francis O. Agricola, Robert V. Faller, Worth D. Bowman
-
Patent number: 4976954Abstract: Improved anticariogenic oral preparations having a pH of about 2.5 to about 5.0 comprise an anticariogenically effective amount of a water-soluble aluminum salt in a surfactant-containing emulsion system suitable for use in the mouth.Type: GrantFiled: November 23, 1987Date of Patent: December 11, 1990Assignee: Purdue Research FoundationInventors: Carl J. Kleber, Mark S. Putt
-
Patent number: 4975271Abstract: A muscosal delivery system is provided for use in treating periodontal disease. The system is composed of a chemotherapeutic agent dissolved in a skin-penetration enhancer. The solution of chemotherapeutic agent and skin-penetration enhancer is placed into the periodontal pocket where the agent is transported into the surrounding gingival tissue by means of the penetration enhancer.Type: GrantFiled: December 19, 1988Date of Patent: December 4, 1990Assignee: Vipont Pharmaceutical, Inc.Inventors: Richard L. Dunn, Kenneth C. Godowski, Ronald J. Harkrader, George L. Southard
-
Patent number: 4952392Abstract: Oral hygiene methods and compositions for reducing plaque and for the prevention and treatment of periodontal diseases of bacterial etiology by significantly reducing bacterial activity in the oral cavity through the inclusion of at least about 0.03% by weight of an extract of the perennial herb periwinkle in the compositions and applying the compositions to the oral cavity.Type: GrantFiled: July 27, 1989Date of Patent: August 28, 1990Assignee: Peri-Oral Dental Products, Inc.Inventor: Neville Thame
-
Patent number: 4950479Abstract: Disclosed is a method for interrupting plaque formation comprising periodically introducing in the oral hygiene cavity an efficatious composition in the form of a dentifrice spray, measured drops, masticatable capsules, liquid centered chewing gums and the like.Type: GrantFiled: November 6, 1986Date of Patent: August 21, 1990Inventors: Ira D. Hill, Robert D. White
-
Patent number: 4945087Abstract: A composition or a final product containing thymol in which the unpleasant, medicinal, or harsh taste of thymol has been masked is disclosed. The taste masking is accomplished utilizing effective amounts of a sugar alcohol, or a mixture of sugar alcohols, and anethole.Type: GrantFiled: March 31, 1988Date of Patent: July 31, 1990Assignee: Warner-Lambert CompanyInventors: Anil K. Talwar, Edward J. Carlin
-
Patent number: 4935225Abstract: An appetite suppressant oral composition containing Benzocaine, high impact flavor and a sweetening agent, in the form of a dental cream or a mouthspray. A novel method of reducing appetite and thereby intended for controlling weight of consumers, which comprises applying to the oral cavity a high impact flavor in a dentifrice or mouthspray.Type: GrantFiled: May 1, 1989Date of Patent: June 19, 1990Inventors: John P. Curtis, Susan E. Wieckowski, Karen J. De Pierro
-
Patent number: 4933172Abstract: 2-(2,6-Dichloro-3-methylphenylamino)benzoic acid and its physiologically acceptable salts are effective in inhibiting the conversion of gingivitis to periodontitis and thus useful in treating destructive periodontal disease. The therapeutic agent can be applied directly to the gingival tissue in a topically administerable pharmaceutical composition or can be introduced and released in the buccal cavity for contact with the gingival tissue through the fluid motion present in the mouth.Type: GrantFiled: October 6, 1988Date of Patent: June 12, 1990Assignee: Warner-Lambert Co.Inventors: Joseph D. Clark, Jr., Ivan T. Myers, Kenneth S. Kornman, Stanley C. Holt
-
Patent number: 4923685Abstract: Aqueous homogeneous preparations containing 0.0025 to 0.1% by weight antimicrobial biguanide compounds, 0.005 to 0.2% by weight of an alkyl glycoside, 0.01 to 0.3% by weight of a water-insoluble aromatic oil, 0.01 to 0.3% by weight of a solubilizer from the group consisting of ethoxylated fatty acid glycerides, ethoxylated fatty acid sorbitan partial esters or fatty acid partial esters of glycerol or sorbitan ethoxylates show high activity despite the low concentration of antimicrobial biguanide compounds. The clear solubility is obtained without ethanol or with only very small contents of up to 15% by weight of ethanol. The preparations are particularly suitable as mouthwashes.Type: GrantFiled: July 28, 1988Date of Patent: May 8, 1990Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Peter Wuelknitz, Rudolf Lehmann, Walter Ploeger, Karlheinz Hill, Franz Forg
-
Patent number: 4920100Abstract: Alkyl glycosides in admixture with bactericidally active alcohols or carboxylic acids in, e.g. aqueous treatment solutions, for potentiating the microbicidal effect thereof.Type: GrantFiled: July 9, 1987Date of Patent: April 24, 1990Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Rudolf Lehmann, Klaus Hachmann, Manfred Biermann, Harald Schnegelberger
-
Patent number: 4917894Abstract: An oral anesthetic composition comprising an anesthetically effective amount of a compound of formula (I) ##STR1## wherein R is alkyl of 2 to 8 carbon atoms or a pharmaceutically acceptable salt thereof and an anesthetically effective amount of a rapid-onset anesthetic selected from the group consisting of benzyl alcohol, phenol, phenolate sodium, hexylresorcinol, menthol, salicyl alcohol and benzocaine in combination with a pharmaceutically acceptable carrier, said carrier being in orally administrable form.Type: GrantFiled: June 29, 1988Date of Patent: April 17, 1990Assignee: Beecham Inc.Inventors: Joseph A. Matthias, Kim L. Bildstein
-
Patent number: 4915936Abstract: Gingivitis and related periodontal problems of the gingival tissues may be treated with a dental hygiene composition comprising an effective amount of a calcium sulfate compound such as calcium sulfate hemihydrate. Preferred compositions comprise mouthwashes and oral rinses containing about 5-90% by weight of calcium sulfate hemihydrate, a liquid carrier such as water, a humectant and an alcohol.Type: GrantFiled: October 31, 1988Date of Patent: April 10, 1990Assignee: United States Gypsum CompanyInventors: Lloyd D. Patterson, Jay W. Palmer
-
Patent number: 4913894Abstract: An appetite suppressant oral composition containing Benzocaine, high impact flavor and a sweetening agent, in the form of a dental cream or a mouthspray. A novel method of reducing appetite and thereby intended for controlling weight of consumers, which comprises applying to the oral cavity a high impact flavor in a dentrifrice or mouthspray.Type: GrantFiled: May 1, 1989Date of Patent: April 3, 1990Assignee: Colgate-Palmolive CompanyInventors: John P. Curtis, Susan E. Wieckowski, Karen J. De Pierro
-
Patent number: 4911918Abstract: An oral composition for preventing periodontal diseases through suppression of the colonization of causative bacteria of periodontal diseases comprises an antibody obtained by immunizing a mammal with at least one antigen selected from the group consisting of periodontal causative bacteria, their pilus and capsule fractions, and aluminum hydroxide for stabilizing said antibody.Type: GrantFiled: June 13, 1986Date of Patent: March 27, 1990Assignee: Lion CorporationInventors: Tatsuo Kiyoshige, Yasuo Kikuchi
-
Patent number: 4900721Abstract: Liquid, aqueous disinfectants based on alcohol and hydrogen peroxide which contain one or more C.sub.2 -C.sub.8 alcohols, hydrogen peroxide or a compound which forms peroxide in aqueous phase, one or more carboxylic acids, one or more microbicidally active nitrogen-containing organic compounds, one or more microbicidally active phenolic compounds, and optionally other active substances and/or auxiliaries typically present in disinfectants, and to the use of such disinfectants for disinfection of the skin and mucous membrane.Type: GrantFiled: June 9, 1987Date of Patent: February 13, 1990Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Klaus Bansemir, Karlheinz Disch, Klaus Hachmann, Rudolf Lehmann, Manfred Biermann, Harald Schnegelberger
-
Patent number: 4883534Abstract: A composition for treating dental infections, e.g. dental caries caused by Strep. mutans, comprises a varnish containing a dentally acceptable antimicrobial agent such as chlorhexidine acetate and benzoin gum in an orally acceptable liquid. The composition can be painted on teeth, allowed to dry thereon to give a transparent, translucent or tooth colored film which is effectively invisible but provides sustained release of the antimicrobial agent to the site of infection over a period of at least four days. The film can be removed at will, e.g. by application of the liquid varnish base.To sustain further the antimicrobial agent in situ and hinder its egress into the oral cavity, a sealing composition may be applied over the varnish layer. The sealing composition is preferably solvated polyurethane which cures by evaporation of solvent.Type: GrantFiled: June 18, 1987Date of Patent: November 28, 1989Assignee: University of Toronto Innovations FoundationsInventors: H. J. Sandham, Thomas E. Balanyk
-
Patent number: 4879106Abstract: A composition for preparing a medicament for topical treatment of paradentium diseases, said composition comprising the ammonium salt of sulfoichthyolic acid, zinc oxide, titanium dioxide and fluid extract of Hamamelis in a pharmaceutically acceptable carrier. Said composition is useful especially for treatment of gingivitis and alveolar pyorrhea.Type: GrantFiled: January 27, 1987Date of Patent: November 7, 1989Inventor: Giorgio Voli
-
Patent number: 4868287Abstract: A poly-amino acid compound capable of inhibiting mineral deposition, which has the structure:poly (X).sub.n poly (Y).sub.mwhereeach X is a residue independently selected from the group consisting of aspartic acid, glutamic acid, phosphoserine, phosphohomoserine, phosphotyrosine, and phosphothreonine,each Y is independently a residue selected from the group consisting of alanine, leucine, isoleucine, valine and glycine,n is 2 to 60,m is 2 to 60, andn+m.gtoreq.5,and wherein poly (X).sub.n may contain up to 10% of the Y residues and poly (Y).sub.m may contain up to 10% of the X residues, and salts thereof.Type: GrantFiled: August 24, 1987Date of Patent: September 19, 1989Assignee: University of South AlabamaInventors: C. Steven Sikes, A. P. Wheeler
-
Patent number: 4866161Abstract: A method of treating a tooth so as to inhibit deposition of a mineral thereon, which comprises contacting the tooth with a mineral deposition inhibitory effective amount of a poly-amino acid compound which has the structure:poly(X).sub.n poly(Y).sub.mwhere each X is a residue independently selected from the group consisting of aspartic acid, glutamic acid, phosphoserine, phosphohomoserine, phosphotyrosine, and phosphothreonine,each Y is independently a residue selected from the group consisting of alanine, leucine, isoleucine, valine and glycine,n is 2 to 60,m is 2 to 60, andn+m<5,and wherein poly (X).sub.n may contain up to 10% of the Y residues and poly (Y).sub.m may contain up to 10% of the X residues, and salts thereof,in combination with an orally acceptable vehicle compatible with said compound.Type: GrantFiled: August 24, 1987Date of Patent: September 12, 1989Assignee: University of South AlabamaInventors: C. Steven Sikes, A. P. Wheeler
-
Patent number: 4861582Abstract: Dental compositions containing bicarbonate anion in combination with a monovalent anion such as fluoride, chloride or thiocyanate and methods of using them in anti-carogenic, antiplaque and antiperiodontopathic therapy are disclosed herein.Type: GrantFiled: July 16, 1986Date of Patent: August 29, 1989Assignee: The Research Foundation of State University of New YorkInventors: Jerry J. Pollock, Thomas F. McNamara
-
Patent number: 4853213Abstract: Oral hygiene methods for reducing plaque and for the treatment of periodontal diseases of bacterial etiology by significantly reducing bacterial activity in the oral cavity through the inclusion of about 0.03% to at least about 10% by weight of a dried methanol extract of the perennial herb periwinkle in compositions and applying the compositions to the oral cavity.Type: GrantFiled: March 16, 1988Date of Patent: August 1, 1989Assignee: Peri-Oral Dental Products, Inc.Inventor: Neville Thame
-
Patent number: 4847070Abstract: Disclosed are oral compositions which are effective against calculus and contain a chelating agent which is an acrylic acid polymer or copolymer or EDTA, a strontium ion source, a fluoride ion source and a pyrophosphate ion source.Type: GrantFiled: October 8, 1987Date of Patent: July 11, 1989Assignee: The Procter & Gamble CompanyInventors: Joseph W. Pyrz, Anthony C. Lanzalaco, Richard J. Sunberg
-
Patent number: 4846650Abstract: The present invention relates to oral compositions, such as dentrifices, toothpastes and mounthwashes, which provide an anticalculus benefit. These compositions comprise a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salts, along with a pharmaceutically-acceptable carrier. The present invention also relates to a method for inhibiting or reducing the development of dental calculus by contacting the oral cavity with a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salt.Type: GrantFiled: August 17, 1987Date of Patent: July 11, 1989Assignee: The Procter & Gamble CompanyInventors: James J. Benedict, Rodney D. Bush, Richard J. Sunberg
-
Patent number: 4842846Abstract: The disclosed compositions for periodontal use are characterized by inclusion of superoxide dismutase, as an active ingredient, in combination with an orally acceptable carrier. Periodontal diseases, in particular alveolar pyorrhea, may be treated and/or prevented by application of superoxide dismutase to oral cavity tissue.Type: GrantFiled: November 20, 1987Date of Patent: June 27, 1989Inventor: Minoru Nakano
-
Patent number: 4839158Abstract: A process for enhancing oral hygiene by reducing oral microflora and for inhibiting the formation of dental plaque by applying, to the oral cavity, a composition containing(a) 0.1 to 40 parts, by weight, of a higher alkyl-N-betaine, having the structure ##STR1## wherein N is a higher alkyl group of from 10-18 carbon atoms, and (b) 0.1 to 40 parts, by weight, of a higher alkyl-N, N-dimethylamine, having the structure ##STR2## wherein R is a higher alkyl group of from 10 to 18 carbon atoms, and (c) acid in an amount sufficient to adjust the pH of the composition from 4.5 to 7.5 when measured in an aqueous solution of components (a) and (b) in a orally acceptable carrier.Type: GrantFiled: July 31, 1987Date of Patent: June 13, 1989Assignee: E. B. Michaels Research Associates Inc.Inventor: Edwin B. Michaels
-
Patent number: 4837007Abstract: The disclosure concerns an oral hygiene product which provides in the mouth a reservoir for the slow release of a therapeutic agent, such as fluoride ions. The product comprises two compositions which are mixed in the mouth or before introduction into the mouth. One composition comprises an aqueous suspension of particles which slowly release the therapeutic agent in salvia. The other composition comprises an aqueous solution of a cationic polymer.Type: GrantFiled: December 5, 1986Date of Patent: June 6, 1989Assignee: Lever Brothers CompanyInventors: Ralph M. Duckworth, Andrew M. Murray
-
Patent number: 4820507Abstract: Oral and dental hygiene preparations containing quaternary ammonium compounds of the formula ##STR1## wherein R.sup.1 is an n-alkyl group, preferably containing from 8 to 12 carbon atoms, R.sup.2 is hydrogen, a CH.sub.3 -group or a CH.sub.2 OH-group and R.sup.3 is a CH.sub.3 -group or a group of the formula --CH.sub.2 --CH(OH)--R.sup.2, A is an inorganic or organic acid anion and n is the basicity of the anion. The quaternary ammonium compounds of formula I can have a plaque inhibiting effect and show only slight antimicrobial activity. R.sup.1 is preferably an n-decyl group, R.sup.2 is hydrogen and R.sup.3 is a CH.sub.3 -group or a 2-hydroxyethyl group. The oral and dent al hygiene preparations also preferably contain fluorides and/or organophosphonates as the anion A.Type: GrantFiled: March 2, 1987Date of Patent: April 11, 1989Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Hans-Juergen Klueppel, Walter Ploeger, Horst Rutzen, Rudolf Lehmann
-
Patent number: 4804530Abstract: This invention relates to pharmaceutical compositions comprising anaerobe-selective antibacterial agents which are substituted or unsubstituted 1,12-dodecanedioic peroxy acids, or their pharmaceutically-acceptable salts or esters. The pharmaceutical compositions of the present invention are especially suitable for oral administration in the form of mouth rinses and toothpastes. These anaerobe-selective antibacterial compositions are useful for treating or preventing anaerobic bacterial infections, especially diseases of the oral cavity, in humans or lower animals.The present invention further relates to a method for treating or preventing anaerobic bacterial infections such as acne, and especially diseases of the oral cavity such as gingivitis and periodontal disease, in humans or lower animals.Type: GrantFiled: July 17, 1987Date of Patent: February 14, 1989Assignee: The Procter & Gamble CompanyInventor: Padmini Sampathkumar
-
Patent number: 4772461Abstract: Disclosed are oral compositions containing particular pyrophosphate salts which provide an anticalculus benefit.Type: GrantFiled: June 9, 1987Date of Patent: September 20, 1988Assignee: The Procter & Gamble CompanyInventors: John J. Parran, Jr., Nabil Y. Sakkab
-
Patent number: 4759925Abstract: The perfluoroalkyl surfactant (PAS) of the general formula C.sub.x F.sub.2x+1 (CH.sub.2).sub.n S(CH.sub.2).sub.n,CO.sub.2 M wherein x is an integer of 3-8, each of n and n' is an interger of 2-4 and may be the same or different and M is hydrogen, an alkali metal or ammonium, provides an oral composition, such as a dentifrice or a mouthwash with effect in prevent plaque formation. A preferred PAS is Zonyl FSA, C.sub.3-8 F.sub.7-17 (CH.sub.2).sub.2 S(CH.sub.2).sub.2 COOLi.Type: GrantFiled: October 8, 1987Date of Patent: July 26, 1988Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, Anthony Esposito
-
Patent number: 4716035Abstract: This invention relates to oral compositions comprising certain organic peroxy acid antigingivitis agents and a source of F.sup.- fluoride ions as an anticaries agent. Organic peroxy acid-based antigingivitis agents useful in the present invention include monoperphthalic acid and its derivatives, and 1,12-dodecanedioic peroxy acid and its derivatives. Sources of F.sup.- fluoride ions for use in the present invention include sodium fluoride, stannous fluoride, strontium fluoride, indium fluoride, and amine fluorides.The present invention further relates to methods for treating or preventing diseases of the oral cavity in humans or lower animals with reduced staining of the teeth or dentures. These methods comprise topically applying to the oral surfaces of the human or lower animal a safe and effective amount of a composition of the present invention.Type: GrantFiled: September 26, 1986Date of Patent: December 29, 1987Assignee: The Procter & Gamble CompanyInventor: Padmini Sampathkumar
-
Patent number: 4689221Abstract: An oral composition which prevents periodontal disease such as gingivitis, periodontitis and alveolar pyorrhoea through the prevention of the colonization of Bacteroides gingivalis comprises an antibody obtained by immunizing a mammal with an antigen selected from Bacteroides gingivalis, its pilus and capsule fractions.Type: GrantFiled: December 27, 1984Date of Patent: August 25, 1987Assignee: Lion CorporationInventors: Tatsuo Kiyoshige, Yasuo Kikuchi, Ichiro Takazoe, Katsuji Okuda
-
Patent number: 4689214Abstract: A novel composition to counter by preventing and controlling breath odor containing as the essential agents, a salt which provides zinc ions, and an ionone ketone terpene derivative.Type: GrantFiled: March 10, 1986Date of Patent: August 25, 1987Assignee: Colgate-Palmolive CompanyInventors: Hollandra P. Niles, Susan Herles, Stephen Shymon, Abdul Gaffar
-
Patent number: 4671959Abstract: Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of:(i) Nutmeg Oil;(ii) Mace Extract;(iii) Neroli Oil;(iv) Valerian Oil;(v) Myristicin;(vi) Isoelemicin; and(vii) Elemicin.Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfumed article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.Type: GrantFiled: May 2, 1986Date of Patent: June 9, 1987Assignees: Yale University, International Flavors & Fragrances Inc.Inventors: Craig B. Warren, Marina A. Munteanu, Gary E. Schwartz, Carlos Benaim, Henry G. Walter, Jr., Ronald S. Leight, Donald A. Withycombe, Braja D. Mookherjee, Robert W. Trenkle
-
Patent number: 4670463Abstract: Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of:(i) Nutmeg Oil;(ii) Mace Extract;(iii) Neroli Oil;(iv) Valerian Oil;(v) Myristicin;(vi) Isoelemicin; and(vii) Elemicin.Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfume article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.Type: GrantFiled: May 2, 1986Date of Patent: June 2, 1987Assignees: Yale University, International Flavors & Fragrances Inc.Inventors: Craig B. Warren, Marina A. Munteanu, Gary E. Schwartz, Carlos Benaim, Henry G. Walter, Jr., Ronald S. Leight, Donald A. Withycombe, Braja D. Mookherjee, Robert W. Trenkle
-
Patent number: 4670252Abstract: This invention relates to a method for treating or preventing anaerobe infections in humans and lower animals. This invention further relates to compositions and kits useful for treating or preventing anaerobe infections according to the method of the present invention.Type: GrantFiled: May 24, 1985Date of Patent: June 2, 1987Assignee: The Procter & Gamble CompanyInventor: Padmini Sampathkumar
-
Patent number: 4670264Abstract: Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of:(i) Nutmeg Oil;(ii) Mace Extract;(iii) Neroli Oil;(iv) Valerian Oil;(v) Myristicin;(vi) Isoelemicin; and(vii) Elemicin.Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfumed article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.Type: GrantFiled: November 21, 1985Date of Patent: June 2, 1987Assignees: International Flavors & Fragrances Inc., Yale UniversityInventors: Craig B. Warren, Marina A. Munteanu, Gary E. Schwartz, Carlos Benaim, Henry G. Walter, Jr., Ronald S. Leight, Donald A. Withycombe, Braja D. Mookherjee, Robert W. Trenkle
-
Patent number: 4657935Abstract: The product which I have invented controls acne on the face and neck areas. It is most effective on infectious, cystic acne, the most serious type of acne. The product which I call Real Acne Control (RAC) is a mixture of 55% water and 45% alcohol. RAC is to be used inside the mouth and throat in a rinsing and gargling fashion without swallowing the mixture. The product is never applied to the outside of the face or throat.The product works because human skin is a permeable membrane and by killing the bacteria in the inner mouth and throat, infections such as acne on the skin surface, are lessened.Type: GrantFiled: July 22, 1985Date of Patent: April 14, 1987Inventor: Carlos Teplicki
-
Patent number: 4581226Abstract: A method of treating various sensitive animal body tissues comprising applying to the tissue a solution prepared from specially processed seawater. The solution is prepared by filtering off-shore seawater to remove debris in small organisms, sterilizing the filtered solution and diluting thereafter with tap water or distilled water to lower the solution's osmolality to about 280 mOs, which renders the solution compatible and isotonic with the tissue to be treated.Type: GrantFiled: May 24, 1985Date of Patent: April 8, 1986Inventor: Richard S. Dillon