Abstract: A suspendible composition comprising a tricyclic compound such as FK 506 substance which is 17-allyl-1,14-dihydroxy-12-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylviny 1]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1 .0.sup.4,9 ]octacos-18-ene-2,3,10,16-tetraone, or the like, and a pharmaceutically acceptable surfactant, which can be used as an orally administrable agent or eye drops and is useful for treating various diseases.

Abstract: A water-dispersible condensate of water-insoluble ultrafine particles of medicine or hormones having a particle size of at largest 4 .mu.m prepared by the steps of heating the medicine or hormone in a vacuum vessel at a temperature of 30.degree. C. higher than the boiling point and at a pressure between 0.01 Torr and 10 Torr to evaporate the medicine or hormone and condensing the medicine or hormone on a recovery plate to obtain the condensate.

Abstract: This invention discloses a liquid body powder which is applied as a lotion or a cream and which then evaporates to a powder. By applying it as a lotion or cream, the cracks and pores of the skin are filled. By virtue of the volatility of the cyclic silicone fluid containing delivery vehicle and its evaporation, a powder results which leaves no greasy residue on the skin. The liquid powder according to the present invention comprises a purified starch powder mixed with a volatile cyclomethicone silicone fluid, preferably in equal amounts by weight.

Abstract: A method of producing .beta.-form thiamine hydrochloride crystals which comprises moistening .alpha.-form thiamine hydrochloride crystals in the presence of .beta.-form thiamine hydrochloride crystals as seed crystals and stirring the mixture and a method of producing pharmaceutical preparations containing .beta.-form thiamine hydrochloride crystals which comprises moistening .alpha.-form thiamine hydrochloride crystals, together with a binder, with water in the presence of .beta.-form thiamine hydrochloride crystals as seed crystals and stirring the mixture..beta.-Form thiamine hydrochloride crystals which are stable and resistant to caking and pharmaceutical preparations containing the same can be produced in a simple and easy manner.

Abstract: Sustained release pharmaceutical compound delivery compositions and methods for their production are disclosed wherein ion exchange resin particles are loaded with releasably bound pharmaceutical compounds prior to incorporation in an erodible polymeric matrix to form microparticulates. The microparticulates are suspended in a fluid medium where the encapsulating polymeric matrix shields the drug loaded ion exchange resin from solvent interaction. Administration to a target tissue site initiations erosion of the polymer matrix and release of the loaded pharmaceutical compound.

Abstract: The water dispersible granule of the present invention contains (a) a pesticidal active ingredient which is solid at room temperature, (b) an anionic surface active agent, and (c) a kaolin series clay having a volume median diameter of 2 .mu.m or more, and it exhibits a good disintegrability-in-water and a high dispersion stability.

Abstract: The systemic absorption after intranasal administration of certain drugs, in particular pharmacologically active polypeptides is enhanced in the presence of a phospholipid, such as a phosphatidylcholine (a lecithin), preferably admixed with a vegetable oil.

Abstract: A one-step process for preparing cross-linked poly-.beta.-alanine as microspheres having narrow size distribution comprises polymerizing acrylamide with a polyfunctional compound copolymerizable with acrylamide (with the polyfunctional compound also acting as the cross-linking agent) in an organic solvent or a mixtured such solvents in the presence of an ionic polymerization initiator and a suspension agent. The resulting microspheres may be impregnated with a pharmaceutically or cosmetically active substance.

Abstract: An ion exchange resin composition which is readily dispersible in water is provided. This resin composition comprises a granulated ion exchange resin, a pharmacologically active ingredient bound thereto with a sugar or sugar alcohol, and a sufficient amount of water, alcohol or aqueous alcohol to facilitate granulation. The invention further comprises a method for the preparation of such ion exchange resin composition.

Abstract: The invention relates to a method by which it is possible to prepare a formulation consisting of thickening or suspending agents and other excipients, having the property of dispersing and dissolving quickly in water or aqueous vehicles, without clot formation, with which it is possible to prepare an extermoraneous homogeneous suspension of solid particles and more particularly of micro-encapsulated drugs, which otherwise have the tendency to precipitate or float.

Abstract: Novel surface-active, storage-stable compositons well adopted for the formulation of a variety of active agents, e.g., biocides, and the conversion thereof into stable, hmogenous liquid suspensions, are comprised of at least one first polyolefinic copolymeric surface-active agent (a) and at least one second mixed sulfate and/or phosphate ester surface-active agent (b).

Abstract: The invention relates to a biocidal fine powder with increased biocidal activity and an agricultural suspension containing the biocidal fine powder and an adjuvant selected from the group consisting of polyoxyalkylene-type nonionic surface active agents and polyoxyalkylene alkyl or alkylaryl ether phosphates or their salts.

Abstract: A dry pesticidal composition of a toxicant having a melting point in a range of from 0.degree. C. to 65.degree. C. (the said range of melting point applies also to the melting point of a mixure of toxicants) containing a hydrocarbon represented by the formula, ##STR1## wherein X.sub.1, X.sub.2, Y.sub.1, Y.sub.2, Z.sub.1 and Z.sub.2, which may be the same or different represent a hydrogen atom or an alkyl group having 2 or less carbon atom, R.sub.1 and R.sub.2, which may be the same or different, represent a hydrogen atom or a methyl group, and n represents 0 or 1.

Abstract: A water insoluble crosslinked poly .beta.-alanine is prepared by crosslinking poly .beta.-alanine with a crosslinking agent selected from the group consisting of formaldehyde and a dialdehyde or by irradiation of said poly .beta.-alanine with Co.sup.60.