Abstract: A photon cold gel includes a cold gel body, wherein a non-woven fabric is arranged at the top of the cold gel body. A plurality of medicine storing cavities is formed under the cold gel body. Medicine bags are separately and fixedly arranged in each of the medicine storing cavities. Each of the medicine bags includes a ventilated cotton cloth, wherein medicines are loaded in the ventilated cotton cloth, a drainage tube which penetrates upwards through the cold gel body and is flush with the top of the non-woven fabric, is fixedly connected to the upper part of each of the medicine bags. Finally, a sealing plug is arranged at the top of each drainage tube. The present photon cold gel is able to form a micro magnetic field via the randomly distributed magnetic powder to treat human body by magnetic therapy while maintaining its primary function.

Abstract: Apparatus for heating plastic preforms with a transport device which transports the plastic preforms during their heating along a predetermined transport path, with a first feed transport device which directly transfers the plastic preforms to the transport device in a transfer region, wherein this first feed transport device having a carrier which can be rotated with respect to an axis of rotation and has a plurality of holding devices which hold the plastic preforms, wherein each of these holding devices is in each case assigned an application device, wherein these application devices being arranged on a carrier which can be rotated about an axis of rotation.

Abstract: Provided is a method for controlling at least one of a container treatment machine and a beverage treatment machine, wherein the treatment machine treats at least one of containers and beverages using predeterminable parameters, wherein at least one control device controls the treatment machine at least temporarily taking into account the parameters, and wherein these parameters are input at least temporarily by an input device, and wherein, by an information output device, information is output at least temporarily to a user, the information being characteristic of a status of at least one of the machine and of data input by the user. According to embodiments of the invention, the information is at least partially output in image form.

Abstract: A device for capping a container with a container cap, for example in a beverage filling plant, includes an isolator for providing a defined atmosphere in the interior thereof; a capper for capping a container with a container cap, which capper is arranged in the isolator; and a cap production device for producing container caps from a hot melt, for example a plastics melt. The cap production device is arranged outside the isolator, and is interconnected with the isolator or is connected to the isolator via a cap transport tunnel in order to feed produced container caps to the capper.

Abstract: Apparatus for producing containers, and in particular beverage containers, having a heating device configured to heat plastic parisons, having at least one first transport device, which transports the plastic parisons along a predetermined transport path, a sterilization device configured to sterilize the plastic parisons, and a forming device arranged downstream of the sterilization device, as seen in a transporting direction of the plastic parisons, and configured to form the plastic parisons into plastic containers by the application of a free-flowing medium, wherein said forming device has a transport chamber within which the plastic parisons are transported. The apparatus has an application device configured to apply a free-flowing sterilization medium, at least temporarily, to the transport chamber.

Abstract: The present invention aims at sterilizing a film without using liquid hydrogen peroxide. Aseptic filling and packaging apparatus 11 has supplying device 24 for gaseous hydrogen peroxide; sterilization chamber 15 through which film sheet F passes, and to which gaseous hydrogen peroxide is supplied from supplying device 24; ventilation chamber 16 through which film sheet F passes, ventilation chamber 16 being located downstream of sterilization chamber 15; ventilators F1 and F3 that ventilate ventilation chamber 16; and filling and packaging chamber 17 that is located downstream of ventilation chamber 16, wherein filling and packaging chamber 17 has film forming device 17d that forms film sheet F into a plastic film packaging bag in a shape of a bag, and filling device 35 that fills the plastic film packaging bag with a material.

Abstract: Methods and apparatus for the sanitization, detoxification, disinfection, high level disinfection, or sterilization of both the interior and exterior surfaces of at least one object.

Abstract: A method of manufacturing a spouted pouch aseptically filled with contents includes a supplying process, a sterilizing process, a stopper opening process, a filling process, a tightly re-stopping process, and a capping process. The sterilizing process, the stopper opening process, the filling process, and the tightly re-stopping process are performed in an aseptic chamber.

Abstract: A method and a device for producing blow-molded containers which are sterile at least in some areas. A preform made of a thermoplastic material is first heated in a heating device on a transport path through a blow-molding machine and then supplied with a pressurized fluid in a blow-molding station of the device. The preform is guided along a channel, which conducts a sterile gas, at least over one sub-section of the transport path of the preform. The transport path of the preform out of the channel is supplied with the sterile gas in order to produce a sterile gas corridor in which at least the opening region of the preform is guided. Multiple radiation sources are arranged along the channel and one behind the other in the transport direction. The radiation sources emit a sterilizing radiation onto the preform and/or onto the channel, and/or onto the sterile gas corridor.

Abstract: To reduce an amount of use of a replacement gas used for replacing air in a container. A gas replacement system includes: a washing machine that washes the container with water; a filling machine that fills the container with a content fluid; a sealing machine that seals the container transferred from the filling machine; a chamber that covers the filling machine and the sealing machine, and contains a replacement gas; and a water discharge mechanism (washing machine) that discharges the water in the container having been carried into the chamber while containing the water out of the container in the chamber. The water in the container is replaced with an ambient gas in the chamber along with the discharge of the water.

Abstract: Disclosed is an inventive method for an aseptic assembly of a multi-component medical device. In this method a first component of the medical device is provided in a first container and a second component of the medical device is provided in a second container. Each of the first and second separated containers have a rupturable portion. The first component in the first container is sterilized using a first sterilization technique and the second component in the second container is sterilized using a second sterilization technique. The first and second containers are joined while arranging the rupturable portions in an overlapping configuration which is aseptically sealed against the surroundings. Finally, one of the components is transferred through the rupturable portions and the components are aseptically assembled to form the medical device as a sterile package.

Abstract: A cap sterilizer (50) includes an infeed chamber (52), a sterilant atomizing chamber (53), and an air rinse chamber (54). At least the infeed chamber (52) and the air rinse chamber (54) are exhausted. Both an exhaust pressure (E2) in the infeed chamber (52) and an exhaust pressure (E4) in the air rinse chamber are higher than an exhaust pressure (E3) in the sterilant atomizing chamber (53), or the sterilant atomizing chamber (53) is not exhausted.

Abstract: A bubble manufacturing container 20 of the present invention includes: a container body 21 having an opening portion; and a rubber stopper 221 provided on the opening portion of the container body 21. The rubber stopper 221 is constituted so that the bubbles 1 of an inside of the container body 21 are able to be taken by piercing an injection needle. It is preferred that the bubble manufacturing container 20 has a fastening portion 222 provided on the rubber stopper 221, having an opening and sealing the container body 21 with the rubber stopper 221. Furthermore, it is preferred that the container body 21 mounts a weight portion.

Abstract: A dishwashing system includes: a conveyor-type dishwasher that washes tableware in a washing machine main body while conveying the tableware by means of a conveyor; a robot device having a robot arm mechanism that is installed in the vicinity of a picking area outside of the washing machine main body in order to pick up tableware that is conveyed to the picking area by conveyors, and to transfer the tableware to a stock area; and a control device that generates an enabling signal relating to operations of the conveyors with respect to the dishwasher.

Abstract: Exemplary hot-fillable plastic containers are disclosed. In some embodiments, the containers may include a threaded neck portion, a body portion, and a base portion including a standing surface and a movable element. In some embodiments, the moveable element may be arranged to be recessed either substantially above, or substantially below, the standing surface in an initial pre-filling position.

Abstract: A wire based additive manufacturing system includes a base movable in a feed direction. Multiple welding lasers are each spatially fixed as the base moves in the feed direction. Multiple cutting lasers are each spatially fixed as the base moves in the feed direction. Multiple wire feed members each feed an individual wire of a plurality of wires onto the base as the base moves in the feed direction. Each one the multiple welding lasers is energized to fuse parallel adjoining ones of the plurality of wires, and each one of the cutting lasers is energized to cut one of the fused wires to complete one of a plurality of wire layers.

Abstract: The present invention is directed to a composition that can be used to deliver an antipsychotic drug such as risperidone, paliperidone or a combination thereof, as an injectable in-situ forming biodegradable implant for extended release providing therapeutic plasma levels from the first day. The composition is in the form of drug suspension on a biodegradable and biocompatible copolymer or copolymers solution using water miscible solvents that is administered in liquid form. Once the composition contacts the body fluids, the polymer matrix hardens retaining the drug, forming a solid or semisolid implant that releases the drug in a continuous manner. Therapeutic plasma levels of the drug can be achieved from the first day up to at least 14 days or more even up to at least four weeks.

Abstract: A method of sterilizing a bottle includes steps of: sterilizing bacteria adhering to a preform (1) made of resin by gasifying a sterilizer, discharging a sterilized gas (G) from a nozzle (6) toward a preform, now traveling, so as to adhere to the preform (1); activating the sterilizer adhering to the preform by blasting hot air (P) to the preform; sterilizing the bacteria adhering to the preform, and removing the sterilizer adhering to the preform (1); heating the preform to a temperature suitable for blow-molding treatment; and blow-molding the preform within a mold (4) to mold the preform into a bottle (2), wherein the above steps are performed sequentially in order. According to the above-mentioned steps, the sterilizer does not enter a blow-molding machine.

Abstract: A method of sterilizing a bottle includes steps of: sterilizing bacteria adhering to a preform made of resin by gasifying a sterilizer, discharging a sterilized gas from a nozzle toward a preform, now traveling, so as to adhere to the preform; activating the sterilizer adhering to the preform by blasting hot air to the preform; sterilizing the bacteria adhering to the preform, and removing the sterilizer adhering to the preform; heating the preform to a temperature suitable for blow-molding treatment; and blow-molding the preform within a mold to mold the preform into a bottle, wherein the above steps are performed sequentially in order. According to the above-mentioned steps, the sterilizer does not enter a blow-molding machine.

Abstract: The present invention is directed to a composition that can be used to deliver an antipsychotic drug such as risperidone as an injectable in-situ forming biodegradable implant for extended release providing therapeutic plasma levels from the first day. The composition is in the form of drug suspension on a biodegradable and biocompatible copolymer or copolymers solution using water miscible solvents that is administered in liquid form. Once the composition contacts the body fluids, the polymer matrix hardens retaining the drug, forming a solid or semisolid implant that releases the drug in a continuous manner. Therapeutic plasma levels of the drug can be achieved since the first day up to at least 14 days or more even up to at least four weeks.

Abstract: Injectable depot compositions, comprising a biocompatible polymer which is a polymer or copolymer based on lactic acid and/or lactic acid plus glycolic acid having a monomer ratio of lactic to glycolic acid in the range from 48:52 to 100:0, a water-miscible solvent having a dipole moment of about 3.7-4.5 D and a dielectric constant of between 30 and 50, and a drug, were found suitable for forming in-situ biodegradable implants which can evoke therapeutic drug plasma levels from the first day and for at least 14 days.

Abstract: A sterilization device has a rod-like body which is capable of being introduced through an aperture into an interior space of containers and which acts upon an inner wall of the containers with radiation. A lifting cam produces a movement in a longitudinal direction, of the containers between the containers and the sterilization device in such a way that the containers are capable of being guided over the rod-like body. A movement device is provided which is capable of producing a relative movement in the longitudinal direction of the containers between the rod-like body and the lifting cam and of altering a relative distance between the lifting cam and the rod-like body.

Abstract: A method of making a packaged antimicrobial suture. The method includes the steps of providing a containment compartment molded from a polymeric resin comprising a polymeric material and an antimicrobial agent, positioning a suture within the containment compartment, the suture comprising one or more surfaces; covering the containment compartment having the suture in an outer package cover having an inner surface, and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the containment compartment to the suture, while retaining an effective amount of the antimicrobial agent on the containment compartment, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment. A packaged antimicrobial suture is also provided.

Abstract: An arrangement is provided to prevent emissions of hydrogen peroxide from a packaging machine forming sealed packaging containers from a packaging material web. The packaging machine has a sterilization portion comprising an inlet chamber, a peroxide bath and an aseptic chamber. The aseptic chamber is held at an overpressure while the inlet chamber is held at an underpressure during normal operation of the packaging machine. The peroxide bath functions as a seal between the inlet chamber and the aseptic chamber. A safety chamber placed in front of the inlet chamber is held at an underpressure to avoid peroxide emissions to the environment. The packaging material web will pass the safety chamber before going into the inlet chamber.

Abstract: A plastic container includes a neck with an opening to an interior of the container, where the neck opening having a first diameter and a second diameter of different lengths. A shoulder portion surrounds the neck of the plastic container. A transfer bead is located on the neck above the shoulder portion where the first diameter of the neck opening is above the transfer bead and the second diameter is below the transfer bead. The transfer bead is advantageously shaped and sized so as to facilitate application and removal of a sterilization solution during the aseptic packaging process.

Abstract: A closure sterilization arrangement for container closures comprises a conveying device that conveys the container closures separately along a conveying path so that they avoid touching one another. An irradiation device generates a radiation sterilizing the container closures and acts upon the container closures with the radiation during the conveying thereof by the conveying device. A rotating device rotates the container closures about a pre-set axis of rotation at least for a time period during their conveying by the conveying device. The irradiation device is arranged with respect to the conveying path of the container closures so that the radiation issuing from the irradiation device strikes both an external peripheral wall of the container closures and an internal region of the container closures, and the irradiation device irradiates the container closures from at least two different radiation directions.

Abstract: Machine (10) and method for treating containers (12) of liquids comprising a loading station (15) into which baskets (23) are loaded containing, according to a desired pattern of disposition, the containers (12) to be subjected to washing, a filling station (18) in which the washed containers (12) are filled with new liquid, and a re-closing station (19) in which the containers (12) are closed by the relative lids (11). The re-closing station (19) comprises a closing device (63) provided with gripper members (70) by means of which the lids (11) are picked up and positioned so as to close the containers (12), and loading members (66) that automatically direct the lids (11) toward the closing device (63) in a manner consistent with the desired pattern of disposition of the containers (12) in the baskets (23).

Abstract: A container and method are provided for storing fat containing liquid products. The container includes a body defining a storage chamber for receiving the product, and a container closure. A first material portion forms at least most of the surface area overlying the storage chamber that can contact any product therein. Neither the body nor the first material portion leach more than a predetermined amount of leachables into the product or undesirably alter a taste profile thereof. A needle penetrable and thermally resealable second material portion either (i) overlies the first material portion and cannot contact any product within the storage chamber, or (ii) forms a substantially lesser surface area overlying the storage chamber that can contact any product therein in comparison to the first material portion. A sealing portion is engageable with the body to form a substantially dry hermetic seal between the container closure and body.

Abstract: A system and method are provided for washing, sanitizing, drying, and refilling beverage bottles, such as beer growlers. The sanitizing system is either built into a counter or may be built into a portable cart. The sanitizing system organizes a wash, rinse, sanitizing, and carbon dioxide nozzles in order of use within a drain basin, so that the operator can quickly and reliably move from one nozzle at an organized cleaning station. Further, the container can be dried, filled, and chilled by the carbon dioxide nozzle, so that the refilled beer can be protected by a head of carbon dioxide, preventing oxidation. Using the present sanitizing system and method thoroughly cleans and sanitizes the beverage container, preventing adulteration of the refilled beverage.

Abstract: A gable top packaging container has a plurality of upstanding side walls including a first side wall, a front wall, a rear wall and a second side wall, wherein the front wall connects to a front gable panel and the back wall connects to a back gable panel, both extending up to a sealed top fin, the first side wall connects to a first side gable panel, and the second side wall connects to a second side gable panel, wherein the walls are separated by crease lines extending in a longitudinal direction of the packaging container, characterized in that the front wall is continuous with the front gable panel, and the back wall is continuous with the back gable panel.

Abstract: The present invention is directed to wetting agent compositions and methods for making and using the wetting agent compositions. The compositions of the invention include a sheeting agent, a defoaming agent, and an association disruption agent. The wetting agent compositions of the present invention result in a faster draining/drying time on most substrates compared to conventional wetting agents. The wetting agent compositions of the present invention are especially suitable for use on plastic substrates.

Abstract: A pre-assembled container closure assembly (1) has a plastic spout body (2) with a tubular neck (4) delimiting a product passage (6) that extends to a mouth opening (8) of the neck. A rotational cap (30) is secured in closed position on the neck. The cap has a cap body including a top wall (31)and a skirt (32). The cap body further includes an annular inner sealing ring (40) depending from the top wall. The inside of the neck is provided with an inward tapering annular guide surface (15) that is contacted by the inner sealing ring when the cap is secured onto the spout body and then causes an elastic deformation of the inner sealing ring and/or the neck.

Abstract: A flexible container, system and method of manufacture can include an in-line system that allows flexible containers of varying sizes to be manufactured in a single relatively high speed and efficient production line and in a single clean room through the use of transport and exchange equipment configured to adeptly handle flexible containers throughout the process.

Abstract: An apparatus and method for sterile filling comprises de-contaminating a needle penetrable surface of a device including a needle penetrable septum and a sealed chamber in fluid communication with the needle penetrable septum. A filling needle penetrates the needle penetrable septum, introduces substance through the filling needle and into the chamber and is, in turn, withdrawn from the septum. A liquid sealant is applied to the penetrated region of the septum. Radiation or energy is applied to the liquid sealant to cure the liquid sealant from a liquid phase to a solid phase.

Abstract: The invention relates to an apparatus for disinfecting container closures, comprising a housing and comprising a transport path which is arranged inside the housing and along which the closures are transported, wherein the transport path has at least partially a spiral configuration. According to the invention, the apparatus comprises a supply device for supplying to the housing a gaseous medium for disinfecting the container closures, and at least one displacement device is provided which can move with respect to the housing and which transports the container closures along the spiral transport path.

Abstract: A method for sterile packaging of a surface modified implantable device includes irradiating a surface of the device such that the hydrophobicity of the surface is decreased and, optionally, the device is simultaneously sterilized. The surface of the sterile, surface-modified implantable device is then covered in a polar solution to prevent hydrophobic recovery of the surface.

Abstract: A method and a device for can manufacture and canning, having cans manufactured in a manufacturing process and filled in a filling process, the manufacturing process being integral with the filling process in one plant, and the cans being transported from the manufacturing process to the filling process in a hygienic conveyor.

Abstract: An apparatus (1) for sterilizing container closures comprises a conduit (2) defining a passage for the closure and having a wall (3) surrounding the passage, spraying means (4) for injecting inside the conduit (2) a sterilization fluid heated and vaporized, drying means for introducing hot air in the conduit (2) and means for heating the wall (3) of the conduit (2) operatively coupled thereto. A method for sterilizing container closures transported inside a conduit (2) having a wall (3) defining internally a passage for the closures comprises the steps of injecting inside the conduit (2) a sterilization fluid heated and vaporized, introducing hot air in the conduit (2) for drying the closures and heating the wall (3) of the conduit (2) by transferring heat directly to the conduit wall (3).

Abstract: The invention relates to a device and a method for filling or packing contents, particularly beverages, food, medications, or the like, into containers. As the containers pass through the device from an inlet to an outlet side, the containers passing through the working chamber have a sterile fluid, particularly sterile air, applied thereto for preventing germ growth. In order to reduce the cleaning effort for lines for the sterile fluid, the invention proposes that a cleaning medium having an internal line is inserted into the line for applying the sterile fluid. The line no longer needs to be disassembled in order to load the sterile fluid. In order to distribute the sterile fluid uniformly throughout the containers in a working chamber, the sterile fluid is distributed in two stages, first by means of the pipe extending into the working chamber, as described above and then through a profile extending over the containers and below the pipe, having openings for passing the sterile fluid.

Abstract: A preform is easily and promptly sterilized. Superheated steam (S) generated from water, and having a temperature of 200° C. to 500° C. and a pressure higher than atmospheric pressure is blasted to entire inner and outer surfaces of a preform (1) including a mouth portion (1a) thereof.

Abstract: An aseptic filler apparatus (30) includes an actuatable fitment plug assembly (500) that may be placed against the bottom of a fitment collar, which is in communication with a flexible bag to be filled with flowable food products, thereby to prevent steam or other gasses or liquids from entering the fill bag when undesirable to do so. The plug assembly (500) includes a plug (502) mounted on a distal end portion of a pivot arm (504). The opposite end of the pivot arm is rotatably axled on a cross pin. A linear actuator (518) is connected to the distal end of a lug (512) projecting transversely from the pivot arm. The opposite end of the linear actuator (518) is pinned to a stationary location, enabling the actuator to pivot the plug (502) from an engaged position against the fitment collar and a retracted position away from the fitment collar.

Abstract: A method for folding a liner for packaging and/or insertion into an overpack. The method may include providing a liner comprising a substantially tubular body portion and a closed top and bottom, and a fitment formed in or affixed to the top of the liner, forming a gusset in the bottom panel of the liner, forming a gusset in the body portion of the liner, and fan-folding the liner. In some embodiments, the top of the liner may be a substantially circular top panel and the bottom of the liner may be a substantially circular bottom panel, with the top panel being attached to one end of the tubular body portion and the bottom panel being attached to an opposite end of the tubular body portion. In other embodiments, the liner may be a flexible, blow molded liner, thereby having no weld seams.

Abstract: The method for producing containers filled with liquids, and in particular with beverages, wherein plastic preforms are heated by a heating device, are then transported to a shaping device and are shaped by this shaping device to form the plastic containers, and the plastic containers are then transported to a filling device and filled with the liquid, and wherein the containers are transported inside a clean room at least during the filling and, before being filled with the liquid inside the clean room, they are at least in part sterilized by a first sterilizing device. According to the invention, before being sterilized by means of the first sterilizing device, the plastic containers are pre-sterilized by means of a second sterilizing device, wherein this pre-sterilization is performed outside the clean room.

Abstract: A drink package is manufactured by a method including the steps of: blasting hydrogen peroxide mist (M) or gas (G) into a container (2) in an erected attitude through a mouth portion (2a); activating the hydrogen peroxide in the container (2) in an inverted attitude by blasting heated aseptic air (N) through the mouth portion (2a) thereof directed downward, and simultaneously, removing foreign substance (P) from the inside of the container (2) by replacing air in the container (2) with the aseptic air (N); filling the container (2) in the erected attitude with drink (a) through the mouth portion (2a) directed upward; and closing the mouth portion (2a) of the container (2) by applying a lid (3) to the mouth portion (2a) of the container (2).

Abstract: There is described a packaging machine for producing sealed packages of pourable food products from a web of packaging material, comprising: an aseptic chamber through which web is fed and within which a sterilizing agent is applied onto web; a station which is arranged downstream from said aseptic chamber and in which a tube formed by web is, in use, fed; and a sealing device which separate chamber and station; packaging machine also comprise a conveyor fluidically connected with station and adapted to convey away residues of sterilizing agent from station.

Abstract: The invention relates to a medical sterile packaging, which defines a receiving space for at least one implant, which is formed for temporary or permanent insertion in a human or animal body, which receiving space is closed in a sterile and germ-proof manner in a storage disposition of the sterile packaging for the sterile packaging of the at least one implant, wherein the sterile packaging is produced from one or more cleanable and sterilisable materials.

Abstract: A unit (10) for filling containers (14), includes an insulator (16) having a body (18) provided with an inlet (E) and an outlet (S), the structure (20) of the body (18) defining a space (V) forming an aseptic working region (22) and including insufflation elements (28) which are arranged in the upper part of the insulator (16) and are able to insufflate a sterile air flow for creating an overpressure inside the space (V). The insufflation elements (28) are arranged in the insulator (16) in such a way as to project a laminar-type flow (F) to lick the outer surface (44) of the containers (14), and the insulator (16) includes evacuation elements (48) which are separate from the inlet (E) and the outlet (S) and used to enable a controlled evacuation of the insufflated sterile air flow (F).

Abstract: A container treatment plant, with a discontinuously working container treatment machine and having a feed conveyor and/or a discharge conveyor each for individual containers, and in the feed conveyor and/or the discharge conveyor, at least two continuously driven, circulating conveyor means supplying each other with individual containers, and where the conveyor means being closer to the discontinuously working container treatment machine in the conveying direction exhibits a closer conveying pitch than the conveying pitch of the conveyor means which is further away. In this manner, a container acceptance and/or transfer interruption caused by the respective cycle standstill of the discontinuously working container treatment machine is compensated by the conveying pitch difference to be able to continuously supply individual containers for the discontinuously working machine or continuously discharge them from the discontinuously working container treatment machine.

Abstract: A system for sterilizing bottles with a gaseous sterilant. The system includes moving means for continuously moving bottles one after another along a path. An assembly is provided for distributing a predetermined amount of the gaseous sterilant from a source of gaseous sterilant to each of the bottles. The assembly includes a plurality of injectors that are movable with the bottles. One of the plurality of injectors is associated with each of the bottles. The injector is fluidly connected to the source of gaseous sterilant when the bottle associated with the injector is disposed along a first portion of the path. The injector is disposed above the bottle when the injector is in a first position. The injector is disposed within an interior of the bottle when the injector is in a second position such that the predetermined amount of the gaseous sterilant is conveyed into the interior of the bottle.

Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.