Abstract: A pharmaceutical composition contains an acid addition salt of a basic drug and a fatty acid or bile acid. The acid addition salts thus formed exhibit enhanced transmucosal and transdermal penetration of the basic drug. The acid addition salts, an inclusion complex containing said salts and a use of said salts are also disclosed.
Type:
Grant
Filed:
April 19, 1999
Date of Patent:
July 3, 2001
Assignee:
Farmarc Nederland B.V.
Inventors:
Lawrence John Penkler, Luéta-Ann De Kock, Darryl Vanstone Whittaker
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