Ovary; Eggs; Embryos Patents (Class 530/853)
  • Follicular regulating protein
    Patent number: 4734398
    Abstract: A protein moiety having a molecular weight of from 12,000 to 15,000 inhibits aromatase levels, stimulates 3.beta.-ol dehydrogenase levels and modulates the formation of mature ova substantially independently of steroidal sex hormones. The moiety may be isolated from follicular effluent or produced by granulosa cell cultures.
    Type: Grant
    Filed: March 9, 1987
    Date of Patent: March 29, 1988
    Assignee: University of Southern California
    Inventor: Gere S. diZerega