Hetero Ring Containing Patents (Class 534/662)
  • Patent number: 10457639
    Abstract: The invention provides methods for the treatment of cancer in a subject comprising administering a dansyl-carbazole compound.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: October 29, 2019
    Assignee: GEORGETOWN UNIVERSITY
    Inventors: Milton L. Brown, Kathryn D. Sheikh, Mikell A. Paige, Partha Banerjee, Shankar Jagadeesh
  • Patent number: 5717076
    Abstract: There are provided a derivative of a metal-encapsulated fullerene having application as a functional material, superconducting material, electronics material or pharmaceutical material, and a method of synthesizing this derivative. The derivative of a metal-encapsulated fullerene having the following structure is synthesized by adding a substituted diazomethane to a metal-encapsulated fullerene and denitrifying in a solvent.
    Type: Grant
    Filed: September 10, 1996
    Date of Patent: February 10, 1998
    Assignee: Doryokuro Kakunenryo Kaihatsu Jigyodan
    Inventors: Kazunori Yamamoto, Hideyuki Funasaka, Takeshi Takahashi, Toshiyasu Suzuki, Yusei Maruyama, Tatsuhisa Kato, Takeshi Akasaka
  • Patent number: 4775747
    Abstract: Transition metal complexes of the compounds of the formulae I and II ##STR1## in which A is an isocylic or heterocyclic aromatic radical, R is --H, halogen, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy, R.sub.1 is --H, C.sub.1 -C.sub.4 -alkyl or phenyl which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, --NO.sub.2, --CONH.sub.2, --CONHR.sub.2 or C.sub.2 -C.sub.5 -N-alkylcarbamoyl, X is --CH.dbd. or --N.dbd. andB is --H, C.sub.1 -C.sub.4 -alkyl, --NHCONH.sub.2, --NHCONH-C.sub.1 -C.sub.4 -alkyl, --NHCONR.sub.2, --NHCSNH.sub.2, --NHCSR.sub.3, --NHC(NH)NH.sub.2, --NHR.sub.2, --NHCOR.sub.3, --NHSO.sub.2 R.sub.3 or a heterocyclic aromatic radical, and R.sub.2 and R.sub.3 are phenyl or substituted phenyl, are suitable for pigmenting high-molecular organic material.
    Type: Grant
    Filed: February 17, 1987
    Date of Patent: October 4, 1988
    Assignee: Ciba-Geigy Corporation
    Inventors: Georg Cseh, Paul Lienhard
  • Patent number: 4649194
    Abstract: 1:2 Metal complexes of the formula ##STR1## wherein X.sub.1 is --O-- or ##STR2## and X.sub.2 is --O-- or ##STR3## the starred atom being attached A.sub.1 or A.sub.2, respectively, A.sub.1 is a diazo component radical of the benzene series,A.sub.2 is a diazo component radical of the benzene or naphthalene series,W is --CH.sub.3 or --COOH,R is hydrogen or --SO.sub.3 H,each of B.sub.1 and B.sub.2 is independently a coupling component radical or a phenolic hydroxy group-containing coupling component radical at least one phenolic hydroxy group of which is etherified or acylated,M is iron, cobalt or chromium, andn is 1 or 2,which complexes are useful as anionic dyestuffs having olive to brown colors for substrates such as natural and regenerated cellulose, natural and synthetic polyamides, polyurethane and anodized aluminum, especially leather.
    Type: Grant
    Filed: July 27, 1983
    Date of Patent: March 10, 1987
    Assignee: Sandoz Ltd.
    Inventor: Heinz Wicki
  • Patent number: 4598030
    Abstract: Photographic elements, diffusion transfer assemblages and coordination complexes are described which employ a novel nondiffusible compound capable of releasing at least one diffusible dye moiety having the formula: ##STR1## wherein: (a) D.sup.1, D.sup.2 and D.sup.3 each independently represents the atoms necessary to complete an aromatic heterocyclic nucleus having at least one ring of 5 to 7 atoms;(b) Z.sup.1 and Z.sup.2 each independently represents the atoms necessary to complete an aromatic carbocyclic or heterocyclic nucleus having at least one ring of 5 to 7 atoms or a ketomethine group;(c) G.sup.1 and G.sup.2 each independently represents a metal chelating group;(d) Me is a polyvalent, hexacoordinate metal ion,(e) CAR represents a ballasted carrier moiety capable of releasing the diffusible dye moiety as a function of development of the silver halide emulsion layer under alkaline conditions; and(f) n is 1, 2 or 3.
    Type: Grant
    Filed: August 2, 1985
    Date of Patent: July 1, 1986
    Assignee: Eastman Kodak Company
    Inventor: James A. Reczek
  • Patent number: 4565884
    Abstract: Bis-platinum complexes having the formula ##STR1## wherein A is a ligand having two pairs of platinum-coordinating acidic groups which are each independently a carboxylate, phenolate, sulfonate or phosphonate group, each said pair being capable of coordinating with a platinum ion to form a 5-10 membered chelate ring; Z is a water-solubilizing group; n is 0 or a positive integer, with the proviso that n is 0 only when at least one of said platinum-coordinating acidic groups is sulfonate or phosphonate or when at least one platinum ion is a Pt(IV) ion; and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are each independently H or a C.sub.1-20 alkyl, aryl, aralkyl, or alkaryl group, or together form one or more C.sub.1-30 alkylene, cycloalkylene, arylene, aralkylene or alkarylene groups; or a pharmaceutically acceptable salt thereof, are useful as readily water-soluble antitumor agents.
    Type: Grant
    Filed: May 10, 1984
    Date of Patent: January 21, 1986
    Assignee: Andrulis Research Corporation
    Inventors: Peter J. Andrulis, Jr., Paul Schwartz