Abstract: Resins resulting from the crosslinking of cyclodextrin with dicarboxylic acid dihalides often show marginal binding capacity for guest molecules and poor kinetics of guest molecule removal because of the limited porosity of the resins. Resins whose apparent bulk density has been reduced by at least 20% show an enhancement in both of the aforementioned properties resulting from an increase in porosity of the resins. Such resins in general can be formed by conducting the crosslinking reaction in the presence of a blowing agent. The resulting materials retained their desirable physical properties for use in a fixed or packed bed.

Abstract: Composites on a porous support of an insolubilized, crosslinked cyclodextrin show improved mass transfer characteristics relative to discrete particles of the same insolubilized cyclodextrin. Dicarboxylic acid dihalides are particularly effective crosslinking agents. The composites can be prepared quite simply and cost effectively by impregnating a support, such as alumina, with a cyclodextrin, then reacting the cyclodextrin within the impregnated support with a suitable dicarboxylic acid dihalide, such as one from the alkane dicarboxylic acid series containing from 4 through 12 carbon atoms.

Abstract: The invention is concerned with a method of preventing adhesions or accretions of body tissues inter se by means of employing a degradable gel of a crosslinked carboxyl-containing polysaccharide. The invention also covers a gel product to be used for this purpose, and a process for preparing said product by means of crosslinking with a di- or polyfunctional expoxide at a pH of from 2 to 5.

Abstract: A method of improving the utility of corn bran (i.e., hulls derived from milling) is provided. The corn bran is crosslinked with a polyvalent compound capable of forming a plurality of covalent bonds to one or more constituents of the corn bran. The crosslinked corn bran finds particular utility in papermaking. Paper furnishes and paper products derived therefrom are also provided.

Abstract: A complex of cyclodextrin and cetylpyridinium chloride is disclosed as a controlled release agent of cetylpyridinium chloride. The cyclodextrin can be either cyclodextrin molecule, a polymer of cyclodextrin or modified cyclodextrin. The method of forming the complex is also disclosed.

Abstract: 6-Iodoethylated starch and process for preparing the same are disclosed. The 6-idodethylated starch contains one iodine attached per 5 glucose units. Said compound is useful as a contrast agent for X-ray examination, especially for opacifying the vascular os lymphatic vessel. Said compound is produced by reacting 6-hydroxyethylated starch with N-iodosuccinimide in the presence of triphenylphosphine.

Abstract: What is disclosed is a cross-linked starch which provides better fluid loss control in well drilling fluids than conventional starches at elevated temperatures. The starch may be derived from any source.

Abstract: The present invention relates to second grade starches and wheat "B" starches in particular which, following conventional modification treatments to produce a correspondingly viscosity-reduced starch, are especially useful in the production of Stein-Hall corrugating adhesives. Corrugated paper board products manufactured using such adhesives have improved properties. In one aspect of the present invention there is provided a modified wheat "B" starch wherein aqueous dispersions of the modified "B" starch have reduced viscosities relative to comparable dispersions of a corresponding unmodified wheat "B" starch, the reduced viscosity not being less than about 12 centipoise grams per cubic centimeter for a specified dispersion.

Abstract: A modified non-waxy starch, the processes for making such starch and the salad dressing produced from the modified starch. The modified starch is etherified with an alkylene oxide to a degree of substitution between about 2 to about 3.5% and in a second step is cross-linked with not more than 0.1% cross-linking agent. The modified starch has a shear resistance of about 40 to about 80%, shear resilience of about 70 to about 100% and a gel strength of about 5.0 to about 32.0 ml.

Abstract: It has been found that certain insoluble hydrophilic cross-linked polysaccharides are useful pharmaceutical agents in diverting water elimination from the renal route to the gastrointestinal route, and removing excess water from the body by the gastrointestinal route. These properties are of specific therapeutic value in the treatment of edema, water intoxication in chronic renal failure, in reducing the frequency of hemodialysis, and in the treatment of other forms of fluid retention such as congestive heart failure, cirrhosis of the liver, and other disorders associated with refractory swelling. Sephadex-brand insoluble hydrophilic, cross-linked dextrans are preferred in the practice of the invention.

Abstract: Instant gelling tapioca or potato starches characterized by forming at least a weak gel having Bloom strengths of about 70 grams are prepared by forming an aqueous slurry of native tapioca or potato starch at a pH of about 5-12, drum drying the slurry to render the starches cold-water-dispersible, and heat treating the drum-dried starch to reduce its viscosity to within defined Brabender viscosity limits. The heat treatment is carried out in a conventional heating device, such as an electric or gas oven or a dextrinizer, for about 1.5-24 hours at about 125.degree.-180.degree. C. Lightly converted (fluidity) starches can also be used to prepare instant gelling starches provided the pH is above 6.5 and the proper time and temperature are selected for the heat-treatment. The instant gelling starch are particularly useful in food systems of the type which gel upon standing, such as pie fillings, jellies and puddings.

Abstract: A process whereby a gelatinized starch having a cationic reagent chemically bound to the starch backbone and a reduced viscosity is prepared by (1) gelatinizing starch and substantially simultaneous with gelatinization reacting said treated starch with an alkyl or alkenyl amine and a water soluble oxidant or (2) simultaneously reacting an alkyl or alkenyl amine and a water soluble oxidant with a gelatinized starch. The process is conducive to the on-site preparation of a thinned cationic starch derivative which can be utilized without additional treatment as a papermaking additive, textile size, waste water treatment, tailing flocculent, etc.

Abstract: Starches useful as tablet disintegrants consist essentially of a free-flowing, crosslinked and pregelatinized starch powder having a moisture content of about 12% by weight or less. The starch is characterized by its uniformly swollen, virtually non-birefringent granules, by a swelling value in cold water of above 3 ml. and below 25 ml., and by an acid viscosity breakdown of 400 B.U. or less, all of which are correlated to this disintegration performance. The better starch disintegrants (i.e. the more highly crosslinked) have swelling values of 18 ml. or less and show little or no breakdown (0-150 B.U.). The modified starches may be used in any tabletting method (e.g. direct compression or granulation), typically in amounts of about 10% by weight or less.

Abstract: The invention pertains to polymeric polydentate complexons (i.e. chelating agents) of general formulae I and II ##STR1## where P is a linear or three-dimensional polymeric skeleton and X is --0-- or ##STR2## while R is H, C.sub.1 -C.sub.6 alkyl, or phenyl or phenyl substituted with 1-2 C.sub.1 -C.sub.6 alkyl or alkoxy groups. Another objective of the invention is a method for producing the polymeric polydentate complexons described above, wherein a compound P -XH, where P and X have the above given meaning, reacts with 4,4'-ethylenebis(2,6-morpholinedione) the presence of an inert solvent and, if it is desired, also in the presence of acidic or basic catalysts, e.g. protic acids, Lewis acids, tertiary amines, and alkaline or alkaline earth salts of carboxylic acids.

Abstract: Method for determining .alpha.-amylase by incubating with a starch substrate, wherein the substrate is based upon particulate starch derivatized with detectable groups for the determination of .alpha.-amylase, the substrate consisting of superficially cross-linked starch or amylose grains having a regulated, reduced swellability, said grains having a diameter of from 0.01 to 0.20 mm; these grains are prepared by suspending non-swollen grains in a solution with only enough cross-linking agent to achieve superficial cross-linking and then derivatizing the grains with the detectable groups for the determination of .alpha.-amylase.

Abstract: A highly absorbent material, especially suitable for use in absorbent disposable products such as sanitary towels and tampons, consisting of a substantially water-insoluble cross-linked gelatinized starch, in which the degree of substitution of the cross-linking groups is from 0.001 to 0.04, which is substituted by ionic groups which are associated with mono- or di-valent counterions, and which has a urine retention value of at least 6 g/g.

Abstract: This invention relates to a process for preparing cold water hydrating starch which, when hydrated in water, produces a short creamy textured paste, especially useful in instant pudding formulations. These properties are attained without the use of the classical types of polyfunctional crosslinking reagents such as epichlorohydrin, phosphorus oxychloride, acrolein, etc. This process comprises treating starch with from 0.1% to 1% chlorine (preferably 0.4-0.6%) as sodium hypochlorite to inhibit the starch, but not to degrade or depolymerize it, and then reacting the inhibited starch with an alkylene oxide to produce a hydroxypropyl starch having a degree of substitution of about 15.5% to about 18.5%.

Abstract: Starch ether derivatives are prepared by reacting a starch base with N-(2-haloethyl)iminobis(methylene)diphosphonic acid or with a N-(alkyl)-N-(2-haloethyl)aminomethylphosphonic acid. The derivatives contain aminophosphonic acid groups (or their salts) as zwitterion substituents which consist of either one or two anionic methylene phosphonic acid groups bound to a cationic nitrogen. Their cationic or anionic characteristics may be increased by introducing suitable cationic or anionic groups either by simultaneous reaction with the aminophosphonic acid reagent or by consecutive reaction either prior to or subsequent to the aminophosphonic acid reaction. They are especially useful as pigment retention aids in paper making processes.

Abstract: A process for making an acetylated cross-linked starch substantially free of acetyl odor and flavor which comprises cross-linking a starch in a slurry, acetylating the cross-linked starch to an acetyl substitution of not more than 2.5%, thereafter washing the starch sufficiently to reduce the ash content to less than 0.20%, preferably forming a slurry of the acetylated cross-linked starch and adjusting the pH to 7 to 9.0, and thereafter drying the starch. The process provides a starch product which is substantially free from off odors or flavors and particularly useful in pudding formulations. Tapioca starch is utilized in preferred embodiments.

Abstract: Crosslinked starch is reacted with an epihalohydrin in the presence of a strong acid catalyst to produce the 3-halo-2-hydroxypropyl ether. Substitution of the halogen with nitrogen-containing compounds enables the preparation of novel water-insoluble cationic, anionic, and chelating starch ethers, as well as starch ethers having degrees of substitution heretofore unattainable in the prior art.

Abstract: A cold-water dispersible, modified starch characterized by forming a gel having a Bloom strength of at least 50 grams is prepared by reacting a tapioca starch with a crosslinking agent to within defined Brabender viscosity limits; converting the crosslinked starch in a sufficient amount to provide the modified starch with gelling properties; and drum-drying the crosslinked and converted starch to obtain the modified starch product. The gelling instant starch thus prepared is particularly useful in food systems of the type which gel upon standing, such as pie filling, jellies, and puddings.

Abstract: A cold-water dispersible, modified starch characterized by forming a gel having a Bloom strength of at least 60 grams is prepared by reacting a potato starch with a crosslinking agent to within defined Brabender viscosity limits sufficient to provide the modified starch with gelling properties and drum-drying the crosslinked starch to obtain the modified starch product. The starch may be optionally converted to a fluidity starch either before or after the crosslinking step and prior to drum drying. The gelling instant starch thus prepared is particularly useful in food systems of the type which gel upon standing, such as pie fillings, jellies, and puddings.

Abstract: A cold-water dispersible, modified starch characterized by forming a gel having a Bloom strength of at least 45 grams is prepared by converting a tapioca starch to a water fluidity of about 10 to 63, preferably 20 to 40; reacting the starch with a crosslinking agent to within defined Brabender viscosity limits sufficient to provide the modified starch with gelling properties; and drum-drying the converted, crosslinked starch to obtain the modified starch product. The gelling instant starch thus prepared is particularly useful in food systems of the type which gel upon standing, such as pie fillings, jellies, and puddings.

Abstract: Dry granular silicon acid, an organic polyol and a silicon tetrahalide are mixed simultaneously to produce an organic halosilicon acid resinous product.

Abstract: The invention relates to a novel sulphated cationic ion exchanger and to a method for preparation thereof. In addition it relates to a method of improving the capacity of an exchange matrix to receive sulphated groups. Although the general attraction of sulphate groups to proteins is known we have found that sulphated ion exchangers selectively bind lipoproteins in blood serum or plasma under suitable conditions. We have also discovered that when hydroxyalkyl groups are introduced into the ion exchanger matrix its capacity for taking up sulphate groups is unexpectedly increased. A method of use of the ion exchanger is also described.

Abstract: A novel class of reactive derivatives of polymers containing HS-groups is disclosed in which derivatives a number of the HS-groups are converted to a disulphide group of the formula -S-S-A-Z, where A is a hydrocarbon residue having 1-10 carbon atoms and Z is a group ##STR1## or acid addition salts of the last mentioned group, where n is 2 or 3, R.sup.1 is 2-pyridyl, 5-nitro-2-pyridyl or 4-pyridyl and R.sup.2 is methyl or ethyl. The novel derivatives may be used, for example, as thiolating agents or as carriers for e.g. enzymes or other proteins etc.

Abstract: A process and apparatus are described for producing modified starch products. In the method of the invention, a slurry of starch is continuously moved at elevated temperature and pressure through a tubular heating zone and the hot fluid mass emerging from the heating zone is forced through a flow restricting zone within which the fluid mass is highly compressed. This highly compressed fluid material emerges from the confining zone into a tubular reaction zone with a sudden release of energy in the form of a fine spray or mist. The compressive forces followed by the sudden energy release act on the starch molecules to temporarily greatly increase the reactivity of the starch within the reaction zone, whereby modified starch products are quickly formed.

Abstract: Water soluble and water swellable highly substituted polysaccharide derivatives are prepared in highly concentrated aqueous solutions under controlled reaction conditions. The resultant derivatives are produced efficiently and readily isolated in solid form.

Abstract: Superoxy-anion-forming metals, such as chromium, manganese, and the like, are removed from materials containing the same by contacting the material with an anionically-modified, nitrogen-containing polymer, such as sulfite-modified, sulfate-modified, or chloride-modified chitosan.

Abstract: Thin-thick, hydroxypropylated, epichlorohydrin cross-linked starch derivatives for continuous process pressure cooking of neutral or acid food systems. The degree of cross-linking for these starch derivatives is carefully controlled so that they are initially low in viscosity and develop full viscosity only under high pressure and temperatures. These characteristics make these starches ideally suited for use in recently developed food canning processes in which initial rapid heat penetration without degrading the starch derivative is necessary for the heat sterilization of the canned foods. For the new continuous retort processing, the usual time allowed for the complete retorting cycle is less than twenty minutes, and this must include heat sterilization. As the retort media using the starch derivative of the invention reaches the heat sterilization temperature it then increases in viscosity to a range which retains the canned food product in a desirable suspension.

Abstract: A thin-thick, hydroxypropylated, epichlorohydrin crosslinked tapioca-based starch derivative for continuous process pressure cooking of acid food systems. The degree of crosslinking of this starch derivative is carefully controlled so that it is initially low in viscosity and develops full viscosity only under high pressure and temperatures. These characteristics make this starch derivative ideally suited for use in recently developed acid medium, food canning processes in which initial rapid heat penetration without degrading the starch derivative is necessary for the heat sterilization of the canned foods. For the new continuous retort processing, the usual time allowed for the complete retorting cycle is less than twenty minutes, and this must include heat sterilization. As the retort medium using the starch derivative of the invention reaches the heat sterilization temperature, it then increases in viscosity to a range which retains the canned food product in a desirable suspension.

Abstract: This invention relates to an improvement in the process for the manufacture of modified starch ethers in which, prior to, during, or after etherification, a reaction with a modifying agent is conducted in a wet alkaline medium, the improvement comprising that, if etherification were the only reaction conducted, an at least preponderantly water-soluble starch ether would be formed, and the modification results in an absorbent modified starch ether more than 40 per cent by weight of which is insoluble in water.

Abstract: Disclosed herein is a method of manufacturing a bonded particulate article by admixing particulate material with a binder system, the binder system being formed by admixing a polyol selected from the group comprising a saccharide, a saccharide polymer, and a glyco protein with glyoxal, with a solvent, and with an alkali halide; forming the admixture in a heated mold; removing the bonded article from the mold; and allowing it to cool.

Abstract: Disclosed herein is a method of manufacturing a resin-like material suitable for formed articles by cross-linking a saccharide-containing substance with glyoxal in water by controlling, by accelerating or retarding, the rate of the crosslinking reaction by the use of an alkali halide by dissolving or dispersing the alkali halide, saccharide-containing substance and glyoxal in water, causing the mixture to react by the application of heat, and removing moisture from the reacted mixture.

Abstract: A granular starch base is reacted with a selected propiolate ester in aqueous medium to produce a granular, acetal cross-linked starch, the cross-linkages of which are substantially removable in acidic medium. The cross-linked starch product thus prepared is useful in producing highly-substituted granular starch derivatives from which the cross-linkages may be readily and substantially removed as desired.

Abstract: An insoluble alkali metal-magnesium starch-xanthate composition is prepared which is capable of removing most heavy metal ions from aqueous solutions. Concentrations of heavy metal ions contained in several industrial effluents were reduced to below the most stringent aqueous discharge limits.

Abstract: Highly substituted granular starches are prepared by reacting the starch in an aqueous system with a reagent capable of producing an acetal cross-linkage; reacting the resultant acetal cross-linked starch with a mono-functional esterifying or etherifying reagent under aqueous alkaline conditions and removing the acetal cross-linkages by treating under acid conditions. The highly substituted starches are particularly useful in operations, such as papermaking, wherein the cross-linkages can be removed and the starch readily dispersed during a relatively low pH starch cooking process.

Abstract: An inorganic alkali halide is employed in a binder system to catalyze the reaction between glyoxal and polyhydroxyl compounds while permitting a controlled reaction rate and control of properties. The binder system has shown good utility as a foundry core binder.

Abstract: Thin-thick, hydroxypropylated, epichlorohydrin cross-linked starch derivatives for continuous process pressure cooking of neutral or acid food systems. The degree of cross-linking for these starch derivatives is carefully controlled so that they are initially low in viscosity and develop full viscosity only under high pressure and temperatures. These characteristics make these starches ideally suited for use in recently developed food canning processes in which initial rapid heat penetration without degrading the starch derivatives is necessary for the heat sterilization of the canned foods. For the new continuous retort processing, the usual time allowed for the complete retorting cycle is less than 20 minutes, and this must include heat sterilization. As the retort media using the starch derivative of the invention reaches the heat sterilization temperature it then increases in viscosity to a range which retains the canned food product in a desirable suspension.

Abstract: Large diameter legume starch granules including starches derived from yellow field pea, Pisum sativum (var) and faba bean, Vicia faba L. (Leguminosae) which have been treated to remove protein and fiber, and to improve color are used to replace scarce arrowroot starch granules as a protective stilt material in microencapsulated coatings, including carbonless copy paper. The "stilt" material is used to prevent premature rupture of the microcapsules and early release of the microencapsulated materials. It has been discovered that the natural granule size, and other granule properties of the yellow field pea and faba bean starches are ideally suited to replace arrowroot starch granules as a protective material when the naturally occurring protein and fiber have been removed, and the color improved.

Abstract: Large diameter starch granules derived from yellow field pea, Pisum sativum (var) and faba bean, Vicia faba L. (Leguminosae) are used to replace scarce arrowroot starch granules as a protective stilt material in microencapsulated coatings, including carbonless copy paper. The "stilt" material is used to prevent premature rupture of the microcapsules and early release of the microencapsulated materials. It has been discovered that the natural granule size, and other granule properties of the yellow field pea and faba bean starches are ideally suited to replace arrowroot starch granules as a protective material. In certain coating processes in which the temperature at the coated surface exceeds the normal pasting temperature of these starch granules, the pasting temperature of the granules can be raised by a crosslinking reaction under temperature and pH conditions to preserve the granular structure of the starch particles.