Recovery From Photographic Film Patents (Class 536/78)
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Patent number: 11560593Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.Type: GrantFiled: March 29, 2022Date of Patent: January 24, 2023Assignee: 10x Genomics, Inc.Inventors: James Michael Chell, Marlon Stoeckius, Jonathan Alles, Caroline Julie Gallant, Christina Galonska, Felice Alessio Bava, Layla Katiraee
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Patent number: 11434538Abstract: Barcoded ligation assay products from individual samples.Type: GrantFiled: May 1, 2020Date of Patent: September 6, 2022Assignee: BioSpyder Technologies, Inc.Inventors: Milos Babic, Christy Lee Trejo, Peter J. Shepard, Joanne M. Yeakley, Bruce Seligmann
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Patent number: 7189464Abstract: In a multi-layer structure of a cellulose acylate film, the averaged degree of acylation of surface layers is controlled in the range of 0.5 to 2.8 by mixing several sorts of cellulose acylates having different averaged degrees of acyation. One of the surface layers is formed on a substrate by casting a solution containing cellulose acylate made of cotton linter. Lubricant particles are added to a solution for the surface layers, and emission compounds to a solution for the inner layers. The obtained cellulose acylate film is excellent in adhesive property to the hydrophobic material without saponification, and adequately used for the polarizing filter, an optical compensation sheet, and liquid crystal display.Type: GrantFiled: March 4, 2004Date of Patent: March 13, 2007Assignee: Fuji Photo Film Co., Ltd.Inventor: Masaru Sugiura
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Patent number: 6258539Abstract: The present invention relate to methods and compositions for simultaneously analyzing multiple different polynucleotides of a polynucleotide composition comprising multiple diverse polynucleotide sequences. The subject methods and compositions may also be applied to analyze or identify single polynucleotides; however, the subject methods and compositions are particularly useful for analyzing large diverse populations of polynucleotides, e.g., cDNA libraries. Most embodiments of the invention involve hybridizing terminus probes (of known base sequence) to adapter-modified restriction fragment generated from polynucleotide for analysis, and subsequently joining the terminus probes and internal fragment probes to each other. The terminus probe hybridizes to bases of restriction endonuclease recognition site present at the terminus of a restriction fragment generated from the polynucleotide for analysis.Type: GrantFiled: April 30, 1999Date of Patent: July 10, 2001Assignee: The Perkin-Elmer CorporationInventors: Michael W. Hunkapiller, John H. Richards
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Patent number: 6232067Abstract: The present invention relate to methods and compositions for simultaneously analyzing multiple different polynucleotides of a polynucleotide composition comprising multiple diverse polynucleotide sequences. The subject methods and compositions may also be applied to analyze or identify single polynucleotides; however, the subject methods and compositions are particularly useful for analyzing large diverse populations of polynucleotides, e.g., cDNA libraries. Most embodiments of the invention involve hybridizing terminus probes (of known base sequence) and internal fragment probes (of known base sequence) at adjacent positions on an adapter-modified restriction fragment generated from polynucleotide for analysis, and subsequently joining the terminus probes and internal fragment probes to each other. The terminus probe hybridizes to bases of restriction endonuclease recognition site present at the terminus of a restriction fragment generated from the polynucleotide for analysis.Type: GrantFiled: August 17, 1998Date of Patent: May 15, 2001Assignee: The Perkin-Elmer CorporationInventors: Michael W. Hunkapiller, John H. Richards
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Patent number: 5543390Abstract: This invention provides novel methods and reagents for specifically delivering biologically active compounds to phagocytic mammalian cells. The invention also relates to specific uptake of such biologically active compounds by phagocytic cells and delivery of such compounds to specific sites intracellularly. The invention specifically relates to methods of facilitating the entry of antimicrobial drugs and other agents into phagocytic cells and for targeting such compounds to specific organelles within the cell. The invention specifically provides compositions of matter and pharmaceutical embodiments of such compositions comprising conjugates of such antimicrobial drugs and agents covalently linked to particulate carriers generally termed microparticles. In particular embodiments, the antimicrobial drug is covalently linked to a microparticle via an organic linker molecule which is the target of a microorganism-specific protein having enzymatic activity.Type: GrantFiled: May 19, 1994Date of Patent: August 6, 1996Assignee: State of Oregon, Acting by and Through the Oregon State Board of Higher Education, Acting for and on Behalf of the Oregon Health Sciences UniversityInventors: Milton B. Yatvin, Michael H. B. Stowell, Vincent S. Gallicchio, Michael J. Meredith
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Patent number: 5500328Abstract: A process is described for recovering cellulose triacetate from scrap photographic film, using aqueous solutions free of organic solvents, by the steps of:a) reducing the film to segments of handlable size;b) oxidizing the film with an oxidizing agent comprising an alkali metal permanganate and a strong acid;c) oxidizing the product of step b) with an alkali metal hypochlorite to remove stain from iron compound and yellow dye;d) bleaching the product of step c) with an alkali metal metabisulfite in an acidic environment; ande) recovering cellulose triacetate.The recovered cellulose triacetate prepared in accordance with this invention has essentially the same spectral absorption at 400 nm as virgin cellulose triacetate and can be used to prepare photographic film base of acceptable color purity.Type: GrantFiled: January 12, 1995Date of Patent: March 19, 1996Assignee: Eastman Kodak CompanyInventors: Robert G. Surash, Craig C. Lewis
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Patent number: 5214137Abstract: A one step process for preparing cellulose diacetates from processed film having cellulose triacetate as a base. The process involves use of an organic acid such as acetic acid and a solvolysis agent such as an alkanol or water. Hydrogen and a hydrogenation catalyst are optionally employed. The process allows for a simple way of recycling a material that presently is not recycled to any appreciable extent.Type: GrantFiled: February 8, 1991Date of Patent: May 25, 1993Assignee: Eastman Kodak CompanyInventors: Alan K. Wilson, Fred D. Barlow, Jr.
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Patent number: 4988617Abstract: Assay for determing the nucleic acid sequence in a region of a nucleic acid test substance having a known normal sequence and a known possible mutation at at least one target nucleotide position. Oligonucleotide probes are selected to anneal to immediately adjacent segments of a substantially complementary test DNA or RNA molecule. The target probe has an end region wherein one of the end region nucleotides is complementary to the normal or abnormal nucleotide at the corresponding target nucleotide position. A linking agent is added under conditions such that when the target nucleotide is correctly base paired, the probes are covalently joined and if not correctly base paired, the probes are incapable of being covalently joined under such conditions. The presence or absence of linking is detected as an indication of the sequence of the target nucleotide.Type: GrantFiled: March 25, 1988Date of Patent: January 29, 1991Assignee: California Institute of TechnologyInventors: Ulf Landegren, Leroy Hood