The Chalcogen, X, Is In A -c(=x)- Group (e.g., 1-phenyl -2-pyrrolidino Hexanone-1, Etc.) Patents (Class 548/571)
  • Patent number: 4405636
    Abstract: N-(1-allyl-2-pyrrolidinyl-methyl)2-methoxy-4-amino-5-methylsulfamoyl benzde and derivatives thereof, which are useful in the treatment of anomalies in cerebral hemodynamics of patients subject to migraines.
    Type: Grant
    Filed: August 25, 1981
    Date of Patent: September 20, 1983
    Assignee: Societe d'Etudes Scientifiques et Industrielles de l'Ile-de France
    Inventors: Jacques Perrot, Michel Thominet
  • Patent number: 4390537
    Abstract: 1-(Substituted-aminoalkoxyphenyl)-2-methylene-1-alkanones, a class of compounds possessing anti-allergic properties for use in the treatment of allergic conditions, such as asthma prepared by etherifying an alkanoylphenol with an aminoalkyl halide, converting the ether formed to a salt of Mannich base by reacting it with a salt of a secondary amine in the presence of formaldehyde or paraformaldehyde and treating the Mannich salt with a weak base to deaminate the same and form the final product.
    Type: Grant
    Filed: May 19, 1982
    Date of Patent: June 28, 1983
    Assignee: Merck & Co., Inc.
    Inventor: Edward J. Cragoe, Jr.