The Metal Is Bonded Directly To Chalcogen, Which Chalcogen Is Attached Directly Or Indirectly To The Hetero Ring By Nonionic Bonding Patents (Class 549/210)
  • Patent number: 4762935
    Abstract: This disclosure describes novel compounds which are useful as precursors in the synthesis of 9-oxo-11.alpha.,16-dihydroxy-16-vinyl-5-cis-13-trans-prostadienoate esters which possess activity as hypotensive agents and/or as vasodilators.
    Type: Grant
    Filed: October 6, 1986
    Date of Patent: August 9, 1988
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Kenneth E. Green, Philip R. Hamann, Jeremy Levin
  • Patent number: 4661516
    Abstract: Diaminocyclohexane platinum complexes having the structural formula ##STR1## wherein: X is a monovalent anion selected from the group consisting of isoascorbate, monosaccharate, saccharate-4-lactone, shikimate, isethionate, 2-aminoethylsulfate, azetidinecarboxylate, proline, hydroxyproline, pipecolinate, cyclopropanecarboxylate, cyclobutanecarboxylate, cyclopentanecarboxylate, cyclopentenecarboxylate, cyclohexanecarboxylate, cyclohexenecarboxylate, bicine, glycine, 2-aminoethanesulfonate, 2-chloroethanesulfonate andY is a divalent anion selected from the group consisting of iminodiacetate, isocitratelactone, furanedicarboxylate, cyclopropane-1,1-dicarboxylate, isocitratomonoethylester, N-methyliminodiacetate, N-(2-hydroxyethyl)-iminodiacetate, N-benzyliminodiacetate, N-phenyliminodiacetate, N-(2-acetamido)iminodiacetate, cyclohexane-1,1-diacetate, trans-1,2-cyclopropanedicarboxylate, trans-1,2-cyclobutanedicarboxylate, trans-1,2-cyclopentanedicarboxylate and trans-1,2-cyclohexanedicarboxylateand their use in
    Type: Grant
    Filed: April 15, 1985
    Date of Patent: April 28, 1987
    Assignee: Research Corporation
    Inventors: David B. Brown, deceased, Abdul R. Khokhar, Miles P. Hacker, John J. McCormack
  • Patent number: 4654334
    Abstract: Manganese complexes of various monovalent and divalent polyether antibiotics are provided which act as coccidiostats and growth promoting agents when administered to food-producing animals such as cattle, sheep, swine and poultry. Soluble manganese salt is added to a fermentation beer containing the polyether antibiotics to form an insoluble, recoverable biomass containing the desired manganese antibiotic complex. This biomass, in a dried form, can be given orally to animals such as cattle, sheep, swine and poultry.The subject manganese complexes include: linear monovalent and divalent polyethers (monensin, nigericin, lasalocid, lysocellin, etc.); non-glycolic monovalent monoglycoside polyethers (septamycin, dianemycin, lenoremycin, carriomycin and antibiotic A-204); mononitrogen-containing divalent pyrrole ethers (calcimycin, X-14547, etc.); polynitrogen-containing divalent pyrrole ethers (A-23187, etc.); glycolic monovalent monoglycoside polyethers (etheromycin, etc.
    Type: Grant
    Filed: February 21, 1984
    Date of Patent: March 31, 1987
    Assignee: International Minerals & Chemical Corp.
    Inventors: Robert D. Williams, David R. Bright, Vernon V. Young, Jerome L. Martin
  • Patent number: 4613670
    Abstract: Water soluble dyestuffs having at least two reactive Lewis base sites are polymerized in a condensation reaction with group IVB metallocenes or group IVA organohalides to yield linear or crosslinked, and colored and/or fluorescent polymeric products. The polydyes are useful in providing permanent coloration of paper, plastics, textiles, paints and the like.
    Type: Grant
    Filed: May 3, 1984
    Date of Patent: September 23, 1986
    Assignee: Wright State University
    Inventors: Jack A. Schroeder, Charles E. Carraher, Jr., Richard A. Schwarz
  • Patent number: 4604471
    Abstract: Furan-3-carbohydroxamates of the formula ##STR1## where R.sup.1 is alkyl, unsubstituted or substituted cycloalkyl or unsubstituted or substituted phenyl, R.sup.2 is methyl or ethyl, R.sup.3 and R.sup.4 independently of one another are each hydrogen, bromine, chlorine, unsubstituted or substituted alkyl, or --CH.sub.2 --COOR.sup.5, where R.sup.5 is unsubstituted or substituted alkyl, and Me is divalent nickel or cobalt, stabilize plastics against the action of light, oxygen and heat. The compounds (I) have only slight intrinsic color.
    Type: Grant
    Filed: November 21, 1984
    Date of Patent: August 5, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter Neumann, Michael Thomas, Stefan Weiss, Hubert Trauth
  • Patent number: 4565812
    Abstract: Compounds of the formula: ##STR1## wherein Z is sulfur or oxygen; R is alkyl of 1 to 7 carbon atoms; R.sup.1 is aryl of 6 to 10 carbon atoms, lower alkyl of 1 to 6 carbon atoms or cycloalkyl of 3 to 8 carbons, all optionally substituted with 1 to 3 halogen atoms; a is 0 or 1; b is 0, 1, or 2; X is independently halo, nitro, trihalomethyl, lower alkyl of 1 to 3 carbon atoms, or lower alkoxy of 1 to 3 carbon atoms are useful as fungicides and insecticides.
    Type: Grant
    Filed: November 30, 1984
    Date of Patent: January 21, 1986
    Assignee: Chevron Research Company
    Inventor: William F. King
  • Patent number: 4462998
    Abstract: A pharmaceutical composition in which the active ingredient is an ascorbate complex of platinum (II) coordinated to ammonia, a monodentate amine ligand or a bidentate amine ligand as, for example, an alkylamine, an alkylenediamine or a cycloalkylamine. Said compositions are useful in the treatment of malignant tumors in animals. They may be administered orally or parenterally and they exhibit high solubility in water and low toxicity.
    Type: Grant
    Filed: November 4, 1983
    Date of Patent: July 31, 1984
    Assignee: Engelhard Corporation
    Inventors: Alan R. Amundsen, Eric W. Stern
  • Patent number: 4457926
    Abstract: There are described ascorbate complexes of platinum(II) coordinated to ammonia, a monodentate amine ligand or a bidentate amine ligand as, for example, an alkylamine, an alkylenediamine or a cycloalkylamine. Said complexes are useful in the treatment of malignant tumors in animals and they are characterized by high solubility in water and low toxicity.
    Type: Grant
    Filed: December 18, 1981
    Date of Patent: July 3, 1984
    Assignee: Engelhard Corporation
    Inventors: Alan R. Amundsen, Eric W. Stern