Carbocyclic Ring Containing Patents (Class 549/560)
  • Patent number: 4909957
    Abstract: Liquid crystalline compounds having an optically active .gamma.-lactone ring of the formula: ##STR1## wherein R.sup.1 is a group selected from the group consisting of ##STR2## n and e are each independently 0 or 1; R.sup.3 is an alkyl group having 1 to 15 carbon atoms; R.sup.2 is a group of the formula: --(CO).sub.m --R.sup.4 ; m is 0 or 1; R.sup.4 is hydrogen atom or an alkyl having 1 to 15 carbon atoms; and the symbol * is an asymmetric carbon atom, and an intermediate thereof, and process for the production of the same.
    Type: Grant
    Filed: September 7, 1988
    Date of Patent: March 20, 1990
    Assignee: Daiso Co., Ltd.
    Inventors: Kazuhiko Sakaguchi, Naoya Kasai, Yoshikazu Takehira, Tohru Kitamura, Yutaka Shiomi
  • Patent number: 4900801
    Abstract: A novel epoxy compound having a chemical structure in which an aromatic ring having a glycidyl raedical attached thereto has a tertiary alkyl radical at its ortho or meta-position. An epoxy resin composition comprising the epoxy compound, a curing agent, and a curing accelerator which cures into a product having a low dielectric constant.
    Type: Grant
    Filed: May 27, 1988
    Date of Patent: February 13, 1990
    Assignee: Mitsui Petrochemical Industries, Ltd.
    Inventors: Toshimasa Takata, Hideo Nakamura
  • Patent number: 4889953
    Abstract: Compounds of the formula: ##STR1## wherein R.sup.1 is a higher alkyl group which may be substituted; R.sup.2 is a hydrogen, a lower alkyl group which may be substituted, a lower alkanoyl group which may be substituted or a lower alkylthiocarbamoyl group; R.sup.3 is a primary to tertiary amino group or a quaternary ammonium group; and n is 2 or 3, and salts thereof, have antitumor activity and platelet activating factor inhibitory activity.
    Type: Grant
    Filed: July 22, 1987
    Date of Patent: December 26, 1989
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Keizo Inoue, Hiroaki Nomura, Tetsuya Okutani
  • Patent number: 4808740
    Abstract: The invention relates to compounds of the formula I or II ##STR1## in which A is a radical ##STR2## R.sup.1 is hydrogen or methyl, R.sup.2 is the radical of an aliphatic, cycloaliphatic, aromatic or araliphatic diol after both of the hydroxyl groups have been removed, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 independently of one another are hydrogen, C.sub.1 -C.sub.6 alkyl, chlorine or bromine, R.sup.7 is a radical of the formula III, IV, V or VI ##STR3## R.sup.8, R.sup.10, R.sup.12 and R.sup.14 are hydrogen, C.sub.1 -C.sub.6 alkyl or phenyl, R.sup.9, R.sup.11, R.sup.13 and R.sup.15 are hydrogen or C.sub.1 -C.sub.6 alkyl and the average value of n (number average) is a number from 1 to 20, it being possible for the radicals R.sup.1 to R.sup.15, within a given molecule, to assume different meanings within the scope of the definitions given.These compounds or also the epoxidized intermediates of the formula X ##STR4## in which R.sup.1 to R.sup.3 are defined above and R.sup.
    Type: Grant
    Filed: January 25, 1988
    Date of Patent: February 28, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Martin Roth, Charles E. Monnier
  • Patent number: 4789711
    Abstract: The invention relates to compounds of the formula I ##STR1## in which A is a group ##STR2## R.sup.1 is hydrogen or methyl R.sup.2 is C.sub.1 -C.sub.6 -alkyl, halogen or phenyl,X is a direct C--C bond, --CH.sub.2 -- or --SO.sub.2 --,m is 0, 1, 2 or 3, n is 0, 1 or 2 andp is 0 or, in the case of X=--CH.sub.2 --, can also be an integer from 1 to 6, with the proviso that the groups --A and --O--A are in the ortho-position relative to one another.The compounds can preferably be used as matrix resins for composite materials.The invention also relates to the allyl glycidyl ether intermediates, from which the compounds of the formula I are as a rule prepared by epoxidation with peracids.
    Type: Grant
    Filed: November 23, 1987
    Date of Patent: December 6, 1988
    Assignee: Ciba-Geigy Corporation
    Inventors: Charles E. Monnier, Sameer H. Eldin, Peter Flury
  • Patent number: 4789751
    Abstract: Ferroelectric (chiral) smectic liquid crystal compounds having an achiral core and chiral tail units derived from (2,3)-epoxyalkyloxiranemethanols possess a high ferroelectric polarization density. These newly made compounds exhibit high speed, multistate electro-optic switching properties which make them ideally suited to certain electro-optic display device applications.
    Type: Grant
    Filed: November 2, 1987
    Date of Patent: December 6, 1988
    Assignee: University Patents, Inc.
    Inventors: David M. Walba, Rohini Vohra
  • Patent number: 4764571
    Abstract: An epoxy resin having the formula: ##STR1## wherein R is a hydrogen atom or a methyl group, and n is an integer of from 0 to 15, and wherein said resin has an epoxy equivalent in the range of 260-345 g/eq.
    Type: Grant
    Filed: January 30, 1987
    Date of Patent: August 16, 1988
    Assignee: Sanyo-Kokusaku Pulp Company Limited
    Inventors: Hiroaki Namba, Minoru Hishinuma
  • Patent number: 4708962
    Abstract: This invention relates to antitumor compositions, and a method for inhibiting, remitting or controlling the growth of tumors or tumor cells utilizing antitumor compositions. More particularly, the antitumor compositions comprise, as active ingredient, an antitumor effective amount of halogenated chamigrenes extracted and derived from red alga and sea hares which diet upon red alga.
    Type: Grant
    Filed: September 4, 1985
    Date of Patent: November 24, 1987
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Tatsuo Higa, Kenneth M. Snader
  • Patent number: 4707534
    Abstract: Diglycidyl ethers of ortho-substituted-4-hydroxyphenylfluorenes, curable compositions comprising the diglycidyl ethers, and cured resins thereof have a high glass transition and an improved modulus of elasticity. The diglycidyl ethers of the invention for use in the curable composition of the invention can be mixtures obtained by the reaction of epihalohydrin with mixtures of fluorenebisphenols obtained by the reaction of one mole of one or more fluorenones with two or more moles or mixtures of two or more ortho-substituted phenols. The compositions are useful in molding and coating applications and in composite articles where the operating temperature of the article or material is elevated.
    Type: Grant
    Filed: December 9, 1986
    Date of Patent: November 17, 1987
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: William J. Schultz
  • Patent number: 4663400
    Abstract: New epoxy resins result from dehydrohalogenation of the reaction product of an epihalohydrin such as epichlorohydrin with the reaction product of a trisphenol such as 1,1,1-tris(hydroxyphenyl)methane with dicyclopentadiene or an oligomer thereof. These new epoxy resins are useful in the electronics industry as encapsulants, potting compounds, laminates and the like.
    Type: Grant
    Filed: April 28, 1986
    Date of Patent: May 5, 1987
    Assignee: The Dow Chemical Company
    Inventors: Chun S. Wang, Gary W. Bogan
  • Patent number: 4659509
    Abstract: There is provided an aroma composition containing a sesquiterpene alcohol having the hexahydroindane skeleton. Such sesquiterpene alcohol has a fantastic aroma reminiscent of a variety of odors based on the woody note and powdery green note and furthermore has high diffusivity and retentivity and accords well with a number of perfume and fragrance materials and flavor materials.
    Type: Grant
    Filed: April 17, 1985
    Date of Patent: April 21, 1987
    Assignee: Kuraray Co., Ltd.
    Inventor: Yoshinori Asakawa
  • Patent number: 4654426
    Abstract: Antimicrobial activity is exhibited by compounds having the formula ##STR1## wherein R.sub.1 is hydrogen or aryl;R.sub.2 is hydroxymethyl, carboxyaldehyde, propenalyl, 3-hydroxy-1-propenyl, or 3-hydroxy-1,2-epoxypropyl; andn is 2 and m is 1 or n is 3 and m is 0; with the proviso that if R.sub.1 is hydrogen, n is 2 and m is 1.
    Type: Grant
    Filed: January 22, 1986
    Date of Patent: March 31, 1987
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Gregory S. Bisacchi, William H. Koster
  • Patent number: 4654264
    Abstract: A sizing agent for use with carbon fibers is described, comprising a compound of formula (I) ##STR1## wherein R is --OH or ##STR2## n is 8 to 100, preferably 10 to 50.
    Type: Grant
    Filed: June 4, 1986
    Date of Patent: March 31, 1987
    Assignee: Mitsubishi Rayon Co., Ltd.
    Inventors: Hajime Asai, Katsumi Anai
  • Patent number: 4652584
    Abstract: Phenoxypropanol derivatives having a 2-acetylenic moiety on the phenyl group thereof of the following formula (I): ##STR1## and their use as anti-hypertensives, e.g. in man. Also part of the invention are pharmaceutical compositions and intermediates used in the synthesis.
    Type: Grant
    Filed: July 13, 1984
    Date of Patent: March 24, 1987
    Assignee: McNeilab, Inc.
    Inventor: John R. Carson
  • Patent number: 4652563
    Abstract: This invention relates to dihydropyridazinone compounds having a cyclopropylmethoxyethyl group in the 6-substituent. These compounds are vasodilators and .beta.-adrenoceptor antagonists. A particular compound of the invention is 6-[4-[3-[2-hydroxy-3-[4-(2-(cyclopropylmethoxy) ethyl)phenoxy]propylamino]propionamido]phenyl]-5-methyl-4,5-dihydro-3 (2H)-pyridazinone.
    Type: Grant
    Filed: May 16, 1985
    Date of Patent: March 24, 1987
    Assignee: Smith Kline & French Laboratories Ltd.
    Inventor: Robert A. Slater
  • Patent number: 4649160
    Abstract: Substituted phenoxy-aminopropanols of the formula ##STR1## wherein R is a branched-chain alkyl of 3 or 4 carbon atoms, R.sup.1 is hydrogen, halogen or lower alkyl and R.sup.2 and R.sup.3, independently, are hydrogen, halogen, lower alkyl, lower alkoxy or lower alkylthio, and pharmaceutically acceptable acid addition salts thereof, are described. A process for their preparation, as well as pharmaceutical preparations containing them are also described. The compounds of formula I and their salts possess cardioselective .beta.-adrenergic blocking activity and antihypertensive activity.
    Type: Grant
    Filed: September 6, 1985
    Date of Patent: March 10, 1987
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Peter J. Machin
  • Patent number: 4632967
    Abstract: Nonhygroscopic, anionic pentacoordinate silicate, for example, ##STR1## soluble in commonly used organic solvents, and useful as a source of fluoride, cyanide or azide anion and as a catalyst or cocatalyst in polymerization systems, for example, the polymerization of methyl methacrylate.
    Type: Grant
    Filed: January 16, 1984
    Date of Patent: December 30, 1986
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: William B. Farnham
  • Patent number: 4621095
    Abstract: The invention relates to bis-azolyl-substituted t-butanol derivatives defined herein under formula (I) and their use as antimycotic agents. Included in the invention are compositions containing said t-butanol derivatives and methods for using said derivatives and compositions containing them for their antimycotic activity.
    Type: Grant
    Filed: August 11, 1983
    Date of Patent: November 4, 1986
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Karl H. Buchel, Manfred Plempel
  • Patent number: 4614826
    Abstract: Disclosed are a polynuclear polyhydric phenol represented by the following general formula [I]: ##STR1## wherein R.sup.1 and R.sup.2 stand for a hydrogen atom or a lower alkyl group, R.sup.3 stands for a hydrogen atom, an alkyl group, an aryl group or a halogen atom, and n is an integer of from 0 to 10,and a polyepoxy compound consisting of a polyglycidyl ether of this polynuclear polyhydric ether. When this polyepoxy compound is combined with a curing agent, a curable epoxy resin composition excellent in the heat resistance characteristics is provided.
    Type: Grant
    Filed: February 27, 1984
    Date of Patent: September 30, 1986
    Assignee: Mitsui Petrochemical Industries, Ltd.
    Inventors: Shigeru Katayama, Takayuki Nakano, Nobuyuki Takeda
  • Patent number: 4612381
    Abstract: Fungicidal triazoles and imidazoles of the formula ##STR1## and stereoisomers thereof, wherein Z is --CH.dbd. or .dbd.N-- and X and Y are oxygen or sulphur. As illustrative values for the other substituents, there may be mentioned alkyl or cycloalkyl for R.sup.1 ; hydrogen and alkyl for R.sup.2 ; alkyl or alkenyl for R.sup.3 and R.sup.4 ; hydrogen or alkyl for R.sup.5 and R.sup.6. Acid salts and metal complexes are included. Also disclosed are various intermediates for preparing the compounds of (I).
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: September 16, 1986
    Assignee: Imperial Chemical Industries PLC
    Inventor: John M. Clough
  • Patent number: 4588828
    Abstract: Antimicrobial activity is exhibited by compounds having the formula ##STR1## wherein R.sub.1 is hydrogen or aryl;R.sub.2 is hydroxymethyl, carboxyaldehyde, propenalyl, 3-hydroxy-1-propenyl, or 3-hydroxy-1,2-epoxypropyl; andn is 2 and m is 1 or n is 3 and m is 0; with the proviso that if R.sub.1 is hydrogen, n is 2 and m is 1.
    Type: Grant
    Filed: August 23, 1984
    Date of Patent: May 13, 1986
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Gregory S. Bisacchi, William H. Koster
  • Patent number: 4579959
    Abstract: Olefinic epoxy compounds are prepared by reacting a material containing at least one terminal --C.dbd.CH group with an epihalohydrin followed by dehydrohalogenation. The materials are useful as halogen scavengers in the preparation of coatings, castings, laminates, composites, and the like.
    Type: Grant
    Filed: February 11, 1985
    Date of Patent: April 1, 1986
    Assignee: The Dow Chemical Company
    Inventor: John L. Massingill
  • Patent number: 4565859
    Abstract: A polyether compound having ether groups and vinyl double bonds represented by formula (I) ##STR1## wherein R.sub.1 represents a residue of an organic compound having l active hydrogen atoms, n.sub.1 through n.sub.l each represents 0 or an integer of from 1 to 100, the sum of the integers represented by n.sub.1 through n.sub.l is from 1 to 100, andl represents an integer of from 1 to 100, and A represents ##STR2## and a process for production thereof; an epoxy resin represented by formula (II) ##STR3## wherein R.sub.1 and n.sub.1 through n.sub.l are defined above, and B is an oxycyclohexane unit having a substituent and is represented by formula (III) ##STR4## wherein X represents a ##STR5## --CH.dbd.CH.sub.2, or ##STR6## groups, wherein R.sub.
    Type: Grant
    Filed: January 29, 1985
    Date of Patent: January 21, 1986
    Assignee: Daicel Chemical Industries, Ltd.
    Inventors: Takaaki Murai, Shoji Watanabe, Kimio Inoue, Toyokazu Yagii
  • Patent number: 4549008
    Abstract: Novel tetraglycidyl ethers of the formula ##STR1## wherein X is a group ##STR2## R is hydrogen or methyl, and n is an integer from 2 to 4. The novel tetraglycidyl ethers can be used in curable mixtures, together with a curing agent for epoxide resins, in particular for the protection of surfaces.
    Type: Grant
    Filed: August 13, 1984
    Date of Patent: October 22, 1985
    Assignee: Ciba-Geigy Corporation
    Inventors: Alfred Renner, Peter Grutter, Rolf Hugi
  • Patent number: 4535148
    Abstract: Polyglycidyl ethers of tricyclodecane are provided which are useful as monomers in the production of cured epoxy resins. Also provided are polyallyl ethers of tricyclodecane which are novel intermediates in the preparation of the polyglycidyl ethers and a method of preparing the polyglycidyl ethers of this invention which uses the novel intermediates.
    Type: Grant
    Filed: August 1, 1984
    Date of Patent: August 13, 1985
    Assignee: Henkel Corporation
    Inventors: Elizabeth J. Gladfelter, Edgar R. Rogier, Edward D. DiDomenico
  • Patent number: 4532341
    Abstract: Oxirane compounds of the formula ##STR1## in which R represents tert-butyl, iso-propyl radical, cyclopropyl, substituted cyclopropyl, cyclopentyl or substituted cyclopentyl, cyclohexyl or substituted cyclohexyl, in each case the substituent being selected from methyl, or phenyl which is optionally mono or di-substituted by identical or different substituents selected from fluorine, chlorine, methyl and trifluoromethyl,Y represents a grouping --OCH.sub.
    Type: Grant
    Filed: June 6, 1983
    Date of Patent: July 30, 1985
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Karl H. Buchel, Klaus Lurssen, Paul-Ernst Frohberger, Wilhelm Brandes
  • Patent number: 4528389
    Abstract: Pentacoordinate silyl enolate and the use thereof as an initiator, without a co-catalyst, in the polymerization of methacrylic monomers, such as methacrylate esters.
    Type: Grant
    Filed: June 12, 1984
    Date of Patent: July 9, 1985
    Assignee: E. I. Du Pont de Nemours And Company
    Inventor: William B. Farnham
  • Patent number: 4518415
    Abstract: Compounds useful as plant growth regulators and fungicides and having the formula ##STR1## and stereoisomers thereof, wherein W is --CH.dbd. or .dbd.N--; Q is optionally substituted aryl, especially optionally substituted phenyl, or optionally substituted aralkyl or alkyl; R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6, which may be the same or different, are H, optionally substituted alkyl, cycloalkyl, aralkyl or phenyl; R.sup.7 and R.sup.8 are H, alkyl or optionally substituted phenyl; and acid addition salts and metal complexes thereof, and processes and intermediates for their preparation.
    Type: Grant
    Filed: January 21, 1983
    Date of Patent: May 21, 1985
    Assignee: Imperial Chemical Industries PLC
    Inventors: Anthony F. Marchington, Timothy Lewis, John M. Clough, Paul A. Worthington, John Dalziel
  • Patent number: 4489091
    Abstract: Novel sulfonate derivatives represented by the formulaR.sub.1 SO.sub.3 CH.sub.2 CO(CH.sub.2).sub.n R.sub.2act to inhibit esterases and chymotripsin and are useful as antilipemic agents, anti-inflammatory agents, immunity controlling agents, etc.
    Type: Grant
    Filed: May 9, 1983
    Date of Patent: December 18, 1984
    Assignee: Taiho Pharmaceutical Company Limited
    Inventors: Setsuro Fujii, Toshihiro Hamakawa, Kazuo Ogawa, Yoshiyuki Muranaka, Sadao Hashimoto
  • Patent number: 4429099
    Abstract: The invention sets forth novel telechelic (terminally functional) prepolymers which may be reacted to form curable epoxides. On account of the incorporation of saturated elastomer chains into the prepolymers improved epoxides arise having increased moisture resistance and less brittleness than conventional epoxides. These prepolymers may be straight chain or three-armed star, emanating from a common phenyl ring nucleus. Molecular weights of the prepolymers range from about 700 to 50,000 (linear) and from about 1000 to about 75,000 (three-arm star). The epoxides are useful as coatings, in adhesives, as additives, and the like.
    Type: Grant
    Filed: November 22, 1982
    Date of Patent: January 31, 1984
    Assignee: The University of Akron
    Inventors: Joseph P. Kennedy, Suhas Guhaniyogi
  • Patent number: 4427686
    Abstract: A compound of the formula (I): ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-6 alkyl;R.sub.2, R.sub.3 and R.sub.4 are the same or different and are chosen from hydrogen, hydroxyl, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy and C.sub.1-4 alkanoyl;G is H or OH; andm and n are independently 1 to 3; with the proviso that when G is OH, one of m or n is 1; is useful in the prophylaxis and treatment of diseases whose symptoms are controlled by the mediators of the allergic response, for example asthma, hay fever, rhinitis and allergic eczema.
    Type: Grant
    Filed: December 8, 1981
    Date of Patent: January 24, 1984
    Assignee: Beecham Group Limited
    Inventors: Derek R. Buckle, Harry Smith
  • Patent number: 4412056
    Abstract: The invention relates to polyglycidyl ethers and provides such compounds based on diphenylol C.sub.7 to C.sub.13 alkanes, and their preparation from the appropriate diphenylol alkanes. The polyglycidyl ethers may be cured with known epoxy resin curing agents and may be used as base materials for the preparation of anionic or cationic aqueous thermosetting paint binders.The polyglycidyl ethers exhibit good compatibility with aliphatic hydrocarbon solvents.
    Type: Grant
    Filed: November 10, 1982
    Date of Patent: October 25, 1983
    Assignee: Shell Oil Company
    Inventors: Johan van Gogh, Hermanus Grol
  • Patent number: 4394496
    Abstract: The invention comprises polyglycidyl ethers of tris(hydroxyphenyl)alkanes, their blends with other epoxy compounds and their cured products. The invention also comprises a process wherein the coupling reaction is carried out in the absence of coupling catalysts and solvents and the subsequent dehydrohalogenation is done in the presence of a methylethylketone/toluene mixture or an equivalent solvent. The epoxides of the invention have superior and unexpected high-temperature properties, without sacrificing other properties such as flex strength, flex modulus and the like.
    Type: Grant
    Filed: October 30, 1981
    Date of Patent: July 19, 1983
    Assignee: The Dow Chemical Company
    Inventor: Paul G. Schrader
  • Patent number: 4384129
    Abstract: Mono- and polyvalent phenolglycidyl ethers which contain in the molecule at least one 1-propenyl group in the ortho- or para-position with respect to the glycidyl ether group, or isomeric mixtures of mono- or polyvalent phenolglycidyl ethers which are propenyl-substituted in the ortho or para-position with respect to the glycidyl ether group and mono- or polyvalent phenolglycidyl ethers which are allyl-substituted in the ortho- or para-position with respect to the glycidyl ether group, the proportion of propenyl groups in the isomeric mixture having to be at least 5 equivalent-%, relative to the sum of the equivalents of propenyl and allyl groups, are obtained by a process wherein the propenyl-substituted phenols, or isomeric mixtures of propenyl- and allyl-substituted phenols, are glycidylated with an epihalohydrin. The novel compounds can be converted, both by use of curing agents for epoxide resins and by radical polymerization, into polymers having valuable mechanical properties.
    Type: Grant
    Filed: April 27, 1981
    Date of Patent: May 17, 1983
    Assignee: Ciba-Geigy Corporation
    Inventors: Sheik A. Zahir, Sameer H. Eldin