Additional Oxygen Containing (e.g., Hydroxy, Ether, Etc.) Patents (Class 554/108)
  • Patent number: 5681915
    Abstract: The use of polyol derivatives with at least two alcoholic hydroxy groups and at least one fatty acid residue per molecule obtainable by reacting a starting polyol with a fatty acid or a fatty acid derivative, which can be obtained by using as a starting polyol diethanolamine, triethanolamine, diisopropanolamine, triisopropanolamine, dibutanolamine, and reaction products of ethylene oxide and/or propylene oxide with ethanolamine, isopropanolamine, butanolamine, or primary or secondary, aliphatic or aromatic amines, as internal lubricants and/or polyol with internal lubricant properties in the production of molded polyurethane parts is described. In this manner a much more uniform distribution of the internal mold lubricant and thus an increase in the ductility of the reaction mixture can be achieved, and even crosslinked polyurethane profiles can be produced by extrusion.
    Type: Grant
    Filed: September 27, 1995
    Date of Patent: October 28, 1997
    Inventors: Josef Lechner, Karl Lechner
  • Patent number: 5670677
    Abstract: A process for the production of color- and odor-stable quaternized fatty acid triethanolamine ester salts comprising the steps ofA) partially or fully esterifying triethanolamine with at least one fatty acid in the presence of hypophosphorous acid;B) adding a peroxide compound and an alkali metal boranate to the esterification product from step A); andC) quaternizing the esterification product with an alkyl halide, a (di)alkyl sulfate or an alkylene oxide in the presence of a phenol derivative and a hydroxycarboxylic acid.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: September 23, 1997
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Oriol Ponsati Obiols, Joaquim Bigorra Llosas
  • Patent number: 5659055
    Abstract: Water or lipid soluble, pharmacologically active, antioxidant, anti-phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA.sub.2 and preventing oxidation. In particular, each compound has at least two fatty moieties and no active hydroxy group. The compound may also have at least one ionizable group, which may be a carboxyl group, and each of the fatty moieties has from sixteen to twenty carbon atoms and at least one cis-unsaturated double bond.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 19, 1997
    Assignee: Virginia Commonwealth University
    Inventors: Richard C. Franson, Raphael M. Ottenbrite
  • Patent number: 5610187
    Abstract: Disclosed are conditioning compositions for the hair and skin containing compounds of the formula (R.sup.1)(R.sup.2)N(CHCH.sub.2 OC(O)R).sub.2 X.sup.- wherein R.sup.1 is alkyl containing 1 to 6 carbon atoms, or hydroxyalkyl containing 1 to 6 carbon atoms; R.sup.2 is alkyl containing 1 to 6 carbon atoms, or benzyl; X.sup.- is an anion; and R is alkyl and alkylene of 12 to 22 carbon atoms having 0 to 3 carbon--carbon double bonds, provided that at least 2 different chain lengths R are present and 0, 1 and 2 such double bonds are present.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 11, 1997
    Assignee: Witco Corporation
    Inventors: Monna M. Manning, Andrea S. Allardice, Floyd Friedli
  • Patent number: 5574179
    Abstract: The present invention relates to softening compounds; stable, homogeneous, preferably concentrated, aqueous liquid and solid textile treatment compositions; and intermediate compositions and/or processes for making said compositions.The compositions of the present invention contain diester quaternary ammonium compounds wherein the fatty acyl groups have an Iodine Value of from greater than about 5 to less than about 100, a cis/trans isomer weight ratio of greater than about 30/70 when the Iodine Value is less than about 25, the level of unsaturation being less than about 65% by weight, wherein said compounds are capable of forming concentrated aqueous compositions with concentrations greater than about 13% by weight at an Iodine Value of greater than about 10 without viscosity modifiers other than normal polar organic solvents present in the raw material of the compound or added electrolyte.
    Type: Grant
    Filed: February 28, 1995
    Date of Patent: November 12, 1996
    Assignee: The Procter & Gamble Company
    Inventors: Errol H. Wahl, Dennis R. Bacon, Ellen S. Baker, Jean-Francois Bodet, Michael E. Burns, Hugo J. M. Demeyere, Charles A. Hensley, Robert Mermelstein, John C. Severns, John H. Shaw, Jr., Michael P. Siklosi, Alice M. Vogel, Jeffrey W. Watson
  • Patent number: 5525709
    Abstract: The invention relates to the preparation of ceramides by a two step process involving conversion of a 2-hydroximino-3-oxo-alkanoate into a 2-alkanoylamido-3-oxo-alkanoate intermediate by acylation of the oxime and reduction of the oxime ester group to an amido group, followed by reduction of the keto and ester group of the intermediate to the 1,3 diol of the ceramide. The oxime acylation and the first reduction may be carried out consecutively or simultaneously. The first reduction is preferably a catalytic hydrogenation and the second reduction is preferably a borohydride reduction.The invention further relates to novel 2-alkanoylamido-3-oxo-alkanoates and 2-alkanoyloximino-3-oxo-alkanoates which are useful as intermediates for conversion into ceramides.
    Type: Grant
    Filed: October 4, 1994
    Date of Patent: June 11, 1996
    Assignee: Unilever Patent Holdings B.V.
    Inventors: Paul N. Davey, Brian J. Hardinge, Christopher P. Newman, Clive D. Richardson
  • Patent number: 5470878
    Abstract: Therapeutic compounds have the formula:(X)j-(non-cyclic core moiety),j being an integer from one to three, the core moiety is non-cyclic and X is a racemic mixture, R or S enantiomer, solvate, hydrate, or salt of: ##STR1## *C is a chiral carbon atom, n is an integer from one to four (preferably from one to three), one or more carbon atoms of (CH.sub.2).sub.n may be substituted by a keto or hydroxy group, and m is an integer from one to fourteen. Independently, R.sub.1 and R.sub.2 may be a hydrogen, a straight or branched chain alkane or alkene of up to twelve carbon atoms in length, or --(CH.sub.2).sub.w R.sub.5, w being an integer from two to fourteen and R.sub.5 being a mono-, di- or tri-substituted or unsubstituted aryl group, substituents on R.sub.5 being hydroxy, chloro, fluoro, bromo, or C.sub.1-6 alkoxy. Or jointly, R.sub.1 and R.sub.2 form a substituted or unsubstituted, saturated or unsaturated heterocyclic group having from four to eight carbon atoms, N being a hetero atom. R.sub.
    Type: Grant
    Filed: December 8, 1993
    Date of Patent: November 28, 1995
    Assignee: Cell Therapeutics, Inc.
    Inventors: John Michnick, Gail E. Underiner, J. Peter Klein, Glenn C. Rice
  • Patent number: 5296622
    Abstract: Quaternized esters having fabric-softening and hydrophilicizing properties are obtained by reaction of unsaturated fatty acids containing at least 40 mol-% transconfigured double bonds or esters thereof with alkanolamines and subsequent quaternization of the reaction products with alkylating agents.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: March 22, 1994
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Guenter Uphues, Uwe Ploog, Rainer Jeschke, Peter Waltenberger
  • Patent number: 5292915
    Abstract: The invention relates to compounds containing carbonate groups and carbonyl groups and having the general formula ##STR1## in which R stands for a C.sub.1 -C.sub.4 -alkyl radical, an aryl radical, or a radical R.sup.1, whereR.sup.1 has the following formula ##STR2## in which R.sup.2 to R.sup.6 stand for H, alkyl, OH, O-alkyl, SH, S-alkyl, halogen, N(alkyl).sub.2, or N(alkyl)(aryl) and at least one but not more than three of the radicals R.sup.2 to R.sup.6 stand for a radical of the formula ##STR3## in which A, B and C stand for alkylene, cycloalkylene, oxaalkylene, polyoxaalkylene or arylene, k and l both stand for an integer from 1 to 80, and the end group Z stands for alkyl, aryl, alkoxycarbonyl, alkoxycarbonyloxy, or aryl.These compounds are suitable for use as emulsifiers for dispersions.
    Type: Grant
    Filed: February 4, 1992
    Date of Patent: March 8, 1994
    Assignee: BASF Aktiengesellschaft
    Inventors: Andreas Boettcher, Manfred Schwartz
  • Patent number: 5266724
    Abstract: A fluorine-containing compound of the formula ##STR1## wherein R.sub.f is a fluoroalkyl ether end group having 5 to 50 carbon atoms, R.sub.1 is an alkyl end group or an aliphatic alkenyl end group, R'''.sub.2 is an aliphatic alkylene group and R.sub.4 is an aliphatic alkylene group having no or one or more carbon atoms. This fluorine-containing compound can be utilized in magnetic recording media in the form of a lubricant composition.
    Type: Grant
    Filed: June 24, 1992
    Date of Patent: November 30, 1993
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Yoshiaki Kai, Takashi Suzuki
  • Patent number: 5219884
    Abstract: The present invention relates to an immunosuppressive agent which comprises at least one compound selected from the compounds of formula ##STR1## wherein R represents a hydrogen atom or an acyl, Y represents carbonyl or hydroxymethylene and represents a single bond or a double bond and their lactones, in an effective amount and a pharmaceutically acceptable carrier; a method of prophylaxis and therapy for suppressing rejection or autoimmune diseases which comprises administering the above-mentioned compound or its lactone in an effective amount; and a novel compound of formula ##STR2## or its lactone.
    Type: Grant
    Filed: March 1, 1990
    Date of Patent: June 15, 1993
    Assignees: Taito Co., Ltd., Yoshitomi Pharmaceutical Industries, Ltd.
    Inventors: Tetsuro Fujita, Takeshi Ikumoto, Shigeo Sasaki, Takeki Okumoto, Kenji Chiba
  • Patent number: 5145611
    Abstract: Carboxylic acid derivatives of the formula ##STR1## R.sub.1 is alkoxy, alkylthio, alkylsulphinyl, alkulsulphonyl, alkylamino, cycloalkyl, or cycloalkoxy or optionally substituted aryl, aryloxy, arylthio, arylsulphinyl, arylsulphonyl or arylamino. R.sub.2 is optionally substituted aryl or, when B is alkylene also a hydrogen atom. A is a straight-chained or branched, saturated or unsaturated alkylene containing 3 to 10 carbon atoms which is optionally interrupted by a heteratom attached to a saturated carbon and has a chain length of at least 3 atoms. Y is S(O).sub.n group or oxygen, n being 0, 1 or 2. B is a valency bond or a straight-chained or branched, saturated or unsaturated alkylene containing 1 to 18 carbon atoms. Physiologically acceptable salts, esters and amides thereof are also included. The compounds are useful in the treatment of metabolic diseases.
    Type: Grant
    Filed: January 12, 1988
    Date of Patent: September 8, 1992
    Assignee: Boehringer Mannheim GmbH
    Inventors: Hans P. Wolff, Ernst-Christian Witte, Hans-Frieder Kuehnle