Chalcogen, Nitrogen Or Halogen Containing Patents (Class 556/144)
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Patent number: 5643895Abstract: Compounds useful in the treatment of inflammation structurally represented as Formula I ##STR1## one of X or Y is H and the other is selected from the group consisting of: ##STR2## or X and Y are taken together to form a ring selected from the group consisting of: ##STR3## as herein defined. The compounds are useful as anti-inflammatory and anti-arthritic agents.Type: GrantFiled: May 29, 1996Date of Patent: July 1, 1997Assignee: The Upjohn CompanyInventors: Richard A. Nugent, David J. Anderson, Stephen T. Schlachter
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Patent number: 5641871Abstract: Metallocenes are prepared by a process in which a metal salt is reacted with at least one alkali metal and with an unsaturated, cyclic hydrocarbon in the presence of a solvent in one reaction step.Type: GrantFiled: October 28, 1994Date of Patent: June 24, 1997Assignee: BASF AktiengesellschaftInventors: Wolfgang Rohde, Hans-Helmut Gortz, Udo Handrich
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Patent number: 5565441Abstract: Compounds useful in the treatment of inflammation structurally represented as Formula I ##STR1## one of X or Y is H and the other is selected from the group consisting of: ##STR2## or X and Y are taken together to form a ring selected from the group consisting of: ##STR3## as herein defined. The compounds are useful as anti-inflammatory and anti-arthritic agents.Type: GrantFiled: February 1, 1995Date of Patent: October 15, 1996Assignee: The Upjohn CompanyInventors: Richard A. Nugent, David J. Anderson, Stephen T. Schlachter
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Patent number: 5550267Abstract: The present invention relates to a process for the synthesis of haloalkylferrocenes, comprising a first stage of reaction, in the presence of AlCl.sub.3 as catalyst and in organic solvent medium, of a carboxylic acid halide or anhydride with ferrocene or an alkylferrocene.After this stage, without prior isolation of the intermediate compound, a metal hydride is added to the reaction mixture.The haloalkylferrocenes are particularly useful as intermediates in the synthesis of combustion catalysts for propellants.Type: GrantFiled: June 6, 1995Date of Patent: August 27, 1996Assignee: Societe Nationale Des Poudres Et ExplosifsInventors: Herve Graindorge, Jean-Claude Mondet, Charles-Henry Vincent
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Patent number: 5362421Abstract: An anisotropically conductive adhesive composition provides electrical conductivity between facing electrodes but maintains electric insulation laterally between adjacent electrodes and comprises (a) a cationically polymerizable monomer, such as a glycidyl epoxy resin; (b) a thermoplastic resin, essentially free of nucleophilic or metal complexing functional groups; (c) optionally, an alcohol containing material; (d) a thermally initiated catalyst system comprising: (1) a salt of an organometallic cation; (2) a cure rate enhancer; and (3) a stabilizing additive; (e) conductive particles; and (f) optionally, a silane coupling agent, wherein the adhesive compositions cure at a temperature of 120.degree.-125.degree. C.Type: GrantFiled: June 16, 1993Date of Patent: November 8, 1994Assignee: Minnesota Mining and Manufacturing CompanyInventors: Michael A. Kropp, Wayne S. Mahoney
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Patent number: 5336795Abstract: Disclosed is a process for the preparation of transition metal complexes having monosubstituted cyclopentadienyl ligands of the general formula: ##STR1## in which monomeric cyclopentadiene is reacted with organic halides or pseudohalides, using a mixture of an alkali metal oxide or hydroxide and an alkaline earth metal oxide or hydroxide as metallating agent in glycol diether as solvent, to form the intermediate monosubstituted cyclopentadiene, which in situ is metallated and reacted with a transition metal halide to give the final product.Type: GrantFiled: February 15, 1994Date of Patent: August 9, 1994Assignee: Witco GmbHInventor: Richard Lisowsky
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Patent number: 5281733Abstract: A process for the carbonylation of substituted metal coordination compounds in the presence of carbon monoxide at a pressure in excess of 400 psig to produce optionally substituted cyclopentadienyl metallic carbonyls, particularly methylcyclopentadienyl manganese tricarbonyl in a thin-film-producing reactor.Type: GrantFiled: June 4, 1992Date of Patent: January 25, 1994Assignee: Ethyl CorporationInventors: Carl O. Inabinet, Fred H. Gregory, David M. Marchand, Robert B. Agee
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Patent number: 5258140Abstract: Charge transfer complexes of formula I[A].sub.2.sup..crclbar. B.sup..sym. (I),whereina) A is a compound of formula II or a mixture of compounds of formula II ##STR1## wherein the R substituents are identical and are H or C.sub.1 -C.sub.4 alkyl, or the adjacent R substituents, taken together, are --(CH.sub.2).sub.3 -- or --(CH.sub.2).sub.4 --; R.sub.1 is H or C.sub.1 -C.sub.4 alkyl; and X.sub.1 is =N--CN, and X.sub.2, X.sub.3 and X.sub.4 are =O or =N--CN, andb) B is a ferrocene or an indenyl derivative whose reduction potential E.sub.1/2 is <0.41 V, based on the standard calomel electrode.The complexes are electric conductors with which polymers can be provided with an antistatic treatment or converted into electric conductors.Type: GrantFiled: January 22, 1993Date of Patent: November 2, 1993Assignee: Ciba-Geigy CorporationInventor: Peter Chetcuti
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Patent number: 5247107Abstract: There is disclosed a process for the preparation of compounds of formula I[R Fe R.sup.2 ].sub.q.sup..sym. X.sup.q.crclbar. (I),wherein R is an anion of formula C.sub.5 H.sub.4 R.sup.1 or C.sub.9 H.sub.7, R.sup.1 is hydrogen, C.sub.1 -C.sub.6 -alkyl or halogen R.sup.2 is a .pi.-arene, X is an anion of valency q and q is 1, 2 or 3, by reacting ferrocene or a ferrocene derivative (C.sub.5 H.sub.4 R.sup.3)Fe(C.sub.5 H.sub.4 R.sup.1) or (C.sub.9 H.sub.7).sub.2 Fe, in which R.sup.3 has one of the meanings of R.sup.1, with at least one mole of a .pi.-arene R.sup.2, followed by the optional replacement of the anion X.sup.q.crclbar. in a manner known per se, the reaction of the ferrocene or ferrocene derivative being carried out in the presence ofa) at least 1.2 mol of a mixture of Al trihalide and Zr(IV) or Hf(IV) tetrahalide, in the presence or absence of a metallic reducing agent, such that at least 0.2 mol of Zr(IV) or Hf(IV) tetrahalide and at least 0.1 mol of Al trihalide are present, or ofb) at least 1.Type: GrantFiled: December 16, 1991Date of Patent: September 21, 1993Assignee: Ciba-Geigy CorporationInventors: Vincent Desobry, Hans O. Doggweiler
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Patent number: 5214175Abstract: The present invention relates to a process for the synthesis of a monohaloalkylferrocene by reaction of hydrogen with a monohaloalkanoylferrocene in the presence of PtO.sub.2 and SnCl.sub.2 as catalyst in an acetic acid medium.In this manner, a crude, particularly pure synthetic product is obtained in a high yield, simply and inexpensively.The monohaloalkylferrocenes are especially useful as surfactants or as intermediates for the synthesis of combustion catalysts for propergols.The present invention also relates to a novel monohaloalkylferrocene, namely 4-chlorobutylferrocene.Type: GrantFiled: September 27, 1991Date of Patent: May 25, 1993Assignee: Societe Nationale des Poudres et ExplosifsInventors: Jean-Claude Gautier, Jean-Guy Melin, Jean-Claude Mondet
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Patent number: 5212311Abstract: A ferrocene derivatives represented by the following formula (I): ##STR1## can be a useful ligand to metals with Lewis acidity and is used as a catalyst for asymmetric synthesis with good enantioselectivity. This ferrocene derivatives is synthesized from a novel haloferrocene derivative represented by formula (II) and the haloferrocene derivative is synthesized from a novel ferrocene derivative represented by formula (III).Type: GrantFiled: October 7, 1991Date of Patent: May 18, 1993Assignee: Tosoh CorporationInventors: Makoto Watanabe, Masaru Uemura, Shuki Araki, Yasuo Butsugan
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Patent number: 5203974Abstract: A process for producing a thin film comprising electrotreating a dispersion or solution obtained by dispersing or dissolving a hydrophobic substance powder in an aqueous medium with a surfactant having a HLB value of 10.0 to 20.0, under conditions for forming a thin film of the hydrophobic substance on a cathode. The thin film of a hydrophobic substance can be formed on base metals such as aluminum, which can be applied to photosensitive materials and the like.Type: GrantFiled: January 24, 1992Date of Patent: April 20, 1993Assignee: Idemitsu Kosan Co., Ltd.Inventors: Hiroshi Kokado, Katsuyoshi Hoshino, Tetsuo Saji, Seiichiro Yokoyama
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Patent number: 5191101Abstract: An energy polymerizable composition and process therefore, comprising a cationically polymerizable material and a catalytically effective amount of an ionic salt of an organometallic complex cation as polymerization initiator, said ionic salt of an organometallic complex cation being capable of adding an intermediate strengeth nucleophile or upon photolysis capable of liberating at least one coordination site, said metal in said organometallic complex cation being selected from elements of Periodic Groups IVB, VB, VIB, VIIB, and VIIIB are disclosed. Certain of the organometallic metallic polymerization initiators are novel cationic salts.Type: GrantFiled: November 26, 1991Date of Patent: March 2, 1993Assignee: Minnesota Mining and Manufacturing CompanyInventors: Michael C. Palazzotto, William A. Hendrickson
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Patent number: 5185369Abstract: Compounds having the formula R-(CH.sub.2).sub.m -CO-R' wherein R is ferrocene, a 5 to 7 member azacyclic system or an 8 to 11 member azabicyclic system, having 1 or 2 nitrogen atoms, or any such system substituted with one or more of F, Cl, Br, OH, C1 to C4 alkyl, C1 to C4 alkoxy, CF.sub.3, phenyl, amino, C1 to C4 alkylamino and di(C1 to C4 alkyl)amino; m is 0 or 1; and R' is--[NH(CH.sub.2).sub.n ].sub.x NH.sub.2, with each n being independently 2 to 5 and x being 1 to 6; ##STR1## with each n being independently 2 to 5, x being 0 to 4, y and z being independently 1 to 5 and the sum of x and the greater of y and z being 1 to 5; or ##STR2## with each a being 2 to 5, each b being 2 to 5, each n being independently 2 to 5, x being 0 to 3, each y being 0 or 1, z being 0 to 3 and x+y+z being 0 to 4, and their pharmaceutically acceptable acid addition salts are potent excitatory amino acid neurotransmitter antagonists.Type: GrantFiled: August 23, 1991Date of Patent: February 9, 1993Assignee: Pfizer Inc.Inventors: Nicholas A. Saccomano, Robert A. Volkmann
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Patent number: 5144052Abstract: A class of ligands capable of solution recognition of anions is defined by a cobalticinium moiety and an adjacent --CO--NH-amide linkage. This class is formed of redox responsive anion receptors, wherein the cobalticinium moiety is acyclic or macrocyclic.Type: GrantFiled: August 30, 1991Date of Patent: September 1, 1992Assignee: Metre International, Inc.Inventors: Paul D. Beer, Jana Hodacova, Sally Stokes
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Patent number: 5135637Abstract: A process for producing an organic thin film, wherein a hydrophobic organic substance is admixed with a ferrocene compound in an aqueous medium to solubilize the hydrophobic organic substance and form a micelle solution. The micelle solution is electrolyzed to form thin film of the hydrophobic organic substance on an anode. The ferrocene compound has the formula: ##STR1## wherein R.sup.1 and R.sup.2 are identical or different and are a hydrogen, a methyl group, a methoxyl group, an amino group, a dimethylamino group, a hydroxyl group or halogen, X is ##STR2## M is an alkali metal or an alkaline earth metal, a is an integer of 1 to 4, b is an integer of 1 to 5, k is an integer of 1 to 18 and m is an integer of 0 to 4.Type: GrantFiled: May 9, 1991Date of Patent: August 4, 1992Assignee: Idemitsu Kosan Co., Ltd.Inventors: Mitsuru Eida, Seiichiro Yokoyama
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Patent number: 5110964Abstract: Disclosed is a process for producing a ferrocenoyl derivative comprising the reaction of ferrocene derivative with monocarboxylic acid or dicarboxylic acid in the presence of a catalyst.The ferrocenoyl derivative obtained by said process is very useful as the intermediate product for various functional materials, among all, for the micelle forming agents (surfactants) in so-called Micellar Disruption Method or the intermediate product of it.Type: GrantFiled: December 12, 1990Date of Patent: May 5, 1992Assignee: Idemitsu Kosan Co., Ltd.Inventors: Yoshio Hiroi, Seiichiro Yokoyama
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Patent number: 5082539Abstract: Novel ferrocene derivatives represented by the general formula: ##STR1## or the general formula: ##STR2## or the general formula: ##STR3## (wherein all the symbols are as described in the specification) are excellent as surfactants.By application of an electrochemical method using the novel ferrocene derivatives or other ferrocene derivatives as a micelle forming agent (surfactant), an organic thin film of a hydrophobic organic substance can be efficiently produced.Type: GrantFiled: January 24, 1990Date of Patent: January 21, 1992Assignee: Idemitsu Kosan Company LimitedInventors: Tetsuo Saji, Katsuyoshi Hoshino
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Patent number: 5079359Abstract: A ferrocene derivatives represented by the following formula (I): ##STR1## can be a useful ligand to metals with Lewis acidity and is used as a catalyst for asymmetric synthesis with good enantioselectivety. This ferrocene derivatives is synthesized from a novel haloferrocene derivative represented by formula (II) and the haloferrocene derivative is synthesized from a novel ferrocene derivative represented by formula (III).Type: GrantFiled: March 8, 1990Date of Patent: January 7, 1992Assignee: Tosoh CorporationInventors: Makoto Watanabe, Masaru Uemura, Shuki Araki, Yasuo Butsugan
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Patent number: 5075471Abstract: Insecticidal compounds of the formula ##STR1## wherein one of A or B is ferrocenyl and the other of A or B is phenyl or substituted phenyl and R is branched alkyl are effective in controlling the Southern Armyworm and Mexican Bean Beetle.Type: GrantFiled: October 9, 1990Date of Patent: December 24, 1991Assignee: Rohm and Haas CompanyInventors: Enrique L. Michelotti, Dat P. Le, Glenn R. Carlson, Anne R. Egan
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Patent number: 5041582Abstract: A ferrocene compound represented by the formula: ##STR1## wherein R.sup.1 and R.sup.2 are identical or different and are a hydrogen, a methyl group, a methoxyl group, an amino group, a dimethylamino group, a hydroxyl group or a halogen,X is ##STR2## Y is ##STR3## M is an alkali metal or an alkaline earth metal, a is an integer of 1 to 4,b is an integer of 1 to 5,k is an integer of 1 to 18 andm is an integer of 0 to 4.The ferrocene compound can be used as a surfactant to produce an organic thin film from various hydrophobic organic substances. The surfactant serves to make the hydrophobic organic substance soluble in an aqueous medium.Type: GrantFiled: March 12, 1990Date of Patent: August 20, 1991Assignee: Idemitsu Kosan Co., Ltd.Inventors: Mitsuru Eida, Seiichiro Yokoyama
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Patent number: 5015748Abstract: Ferrocene compounds represented by the formula: ##STR1## wherein A indicates ##STR2## wherein X is --CH.sub.2 --, --O--, ##STR3## G is a hydrogen atom, a methyl group, or an ethyl group, R.sup.4 is a hydrogen atom, a methyl group or an ethyl group, and m is a positive integer satisfying the expression 0.ltoreq.k+m.ltoreq.10, Z is --O-- or ##STR4## and R.sup.1 and R.sup.2 are identical or different and each is H, NH.sub.2, N(CH.sub.3).sub.2, CH.sub.3, CH.sub.3 O, OH or a halogen atom, and R.sup.3 is a hydrogen atom or a methyl group, k is a positive integer satisfying the expression 0.ltoreq.k+m.ltoreq.10, and n is a real number of 2 to 70, a is an integer of 1 to 4, and b is an integer of 1 to 5. Also provided by the invention are surfactants containing said ferrocene compounds.Type: GrantFiled: September 8, 1989Date of Patent: May 14, 1991Assignee: Idemitsu Kosan Co., Ltd.Inventors: Mitsuru Eida, Yoshio Hiroi, Seiichiro Yokoyama
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Patent number: 4952713Abstract: The present invention constitutes a class of organometallic complexes which reversibly react with hydrogen to form dihydrides and processes by which these compounds can be utilized. The class includes bimetallic complexes in which two cyclopentadienyl rings are bridged together and also separately .pi.-bonded to two transition metal atoms. The transition metals are believed to bond with the hydrogen in forming the dihydride. Transition metals such as Fe, Mn or Co may be employed in the complexes although Cr constitutes the preferred metal. A multiple number of ancilliary ligands such as CO are bonded to the metal atoms in the complexes. Alkyl groups and the like may be substituted on the cyclopentadienyl rings. These organometallic compounds may be used in absorption/desorption systems and in facilitated transport membrane systems for storing and separating out H.sub.2 from mixed gas streams such as the produce gas from coal gasification processes.Type: GrantFiled: June 2, 1988Date of Patent: August 28, 1990Assignee: Battelle Memorial InstituteInventors: Michael A. Lilga, Richard T. Hallen
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Patent number: 4767873Abstract: The invention describes a helicene compound having the structure ##SPC1##which contains seven six-membered conjugated aromatic rings capped by two five-membered rings which do not superimpose on each other.The invention also describes a helical metallocene oligomer capped by unsaturated five-membered rings, having the structure: ##SPC2##wherein M is a transition metal halide and n=1 to 100.Method for the preparation of these compounds are also presented.Type: GrantFiled: September 10, 1986Date of Patent: August 30, 1988Assignee: The Trustees of Columbia University in the City of New YorkInventors: Thomas J. Katz, Anantha Sudhakar
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Patent number: 4699987Abstract: Perfluoroalkylcyclopentadienylthallium compounds of the general formula: ##STR1## wherein n=1-5 are disclosed which are useful to modify the properties of transition metal complexes by the introduction of an electron-withdrawing perfluoroalkylcyclopentadienyl moiety thereinto.Type: GrantFiled: June 3, 1986Date of Patent: October 13, 1987Assignee: Regents of the University of MinnesotaInventors: Paul G. Gassman, Charles H. Winter