Patent number: 9663545
Abstract: The invention relates to compounds characterized by a general formula (1), wherein X is a group described by a general formula —Kp—Fl—Kq—, wherein Fl is —C(?O)—, —C(?S)—, with l being 0 or 1, Kp is a Cp-alkyl with p being 0, 1, 2, 3 or 4, Kq is a Cq-alkyl with q being 0, 1, 2, 3 or 4, and wherein n of R1n is 0, 1, 2, 3, 4 or 5, and each R1 independently from any other R1 is —C(?O)OR2, —C(?O)NR22, —C(?O)SR2, —C(?S)OR2, —C(NH)NR22, CN4H2, —NR22, —C(?O)R2, —C(?S)R2, —OR2, —SR2, —CF3, —OCF3, —SCF3, —SOCF3, —SO2CF3, —CN, —NO2, —F, —Cl, —Br or —I, with each R2 independently from any other R2 being a hydrogen or C1-C4 alkyl, and wherein OM is an organometallic compound independently selected from the group of an unsubstituted or substituted metal sandwich compound, an unsubstituted or substituted half metal sandwich compound or a metal carbonyl compound and their use in a method for treatment of infections by helminths.
Type:
Grant
Filed:
July 1, 2014
Date of Patent:
May 30, 2017
Assignees:
UNIVERSITAT ZURICH, THE UNIVERSITY OF MELBOURNE
Inventors:
Jeannine Hess, Malay Patra, Gilles Gasser, Abdul Jabbar, Robin B. Gasser
Publication number: 20040127690
Abstract: The present invention provides an improved, economical and environmentally benign process for metal complexes of acetylacetone having the general formula, M(acac)n wherein M is a metal cation selected from the group consisting of Fe, Co, Ni, Cu, Zn, Al, Ca, Mg, Mo, Ru, Re, U, Th, Ce, Na, K, Rb, Cs, V, Cr, and Mn etc., n is an integer which corresponds to the electrovalence of M, are obtained by reacting the corresponding metal hydroxide, metal hydrated oxide or metal oxide with a stoichiometric amount of acetylacetone and separating the product.
Type:
Application
Filed:
December 31, 2002
Publication date:
July 1, 2004
Applicant:
Council of Scientific and Industrial Research
Inventors:
Mihir Kanti Chaudhari, Sanjay Kumar Dehury, Siddhartha Sankar Dhar, Upasana Bora, Boyapati Manoranjan Choudary, Lakshmi Kantam Mannepalli