Chalcogen, Nitrogen, Or Additional -c(=x)- Attached Directly To The Nitrogen By Nonionic Bonding (x Is Chalcogen) Patents (Class 558/233)
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Publication number: 20140116292Abstract: The present invention relates to a cellulose acetate film used for optical compensation and a retardation enhancer used therein, and relates to a cellulose acetate film which has a high retardation value in the thickness direction (Rth).Type: ApplicationFiled: June 20, 2012Publication date: May 1, 2014Applicant: SK INNOVATION CO., LTD.Inventors: Won Yeob Kim, Min Joung Im, Seung Eon Lee, Myoung Lae Kim, Yong Gyun Cho, Sang Yeup Lee, Ki Yup Kim
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Patent number: 8283095Abstract: It is an object of the present invention to provide a photopolymerization initiator composition having high sensitivity and excellent storage properties, a photosensitive composition containing the photopolymerization initiator composition, and a thiourethane compound preferable for the photopolymerization initiator composition. The thiourethane compound of the present invention has 2 to 6 units each of which contains a moiety represented by the following formula (i) and a moiety represented by the following formula (ii). wherein R1 is a hydrogen atom or a methyl group, and R2 is —CO—, —COO— or —COOR3— (wherein R3 is an alkylene group of 2 to 6 carbon atoms).Type: GrantFiled: August 14, 2007Date of Patent: October 9, 2012Assignee: Showa Denko K.K.Inventors: Haruhiko Ikeda, Hideo Miyata, Yotaro Hattori, Katsumi Murofushi
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Patent number: 8283453Abstract: The present invention provides a method for selectively placing carbon nanotubes on a substrate surface by using functionalized carbon nanotubes having an organic compound that is covalently bonded to such carbon nanotubes. The organic compound comprises at least two functional groups, the first of which is capable of forming covalent bonds with carbon nanotubes, and the second of which is capable of selectively bonding metal oxides. Such functionalized carbon nanotubes are contacted with a substrate surface that has at least one portion containing a metal oxide. The second functional group of the organic compound selectively bonds to the metal oxide, so as to selectively place the functionalized carbon nanotubes on the at least one portion of the substrate surface that comprises the metal oxide.Type: GrantFiled: August 14, 2009Date of Patent: October 9, 2012Assignee: International Business Machines CorporationInventors: Ali Afzali-Ardakani, Phaedon Avouris, James B. Hannon, Christian Klinke
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Patent number: 7935727Abstract: Compounds having a biphenyl group substituted with a phenyl or heteroaromatic group, as shown in Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis:Type: GrantFiled: October 13, 2006Date of Patent: May 3, 2011Assignee: Merck Sharp & Dohme Corp.Inventors: Yi-Heng Chen, Zhijian Lu, Peter J. Sinclair
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Publication number: 20100196826Abstract: Photopolymerisable systems for coatings or photolithography comprising radically photopolimerisable oligomers and/or monomers having ethylenically unsaturated groups and, as photoinitiator, at least one compound of formula (I).Type: ApplicationFiled: September 5, 2008Publication date: August 5, 2010Inventors: Stefano Romagnano, Gabriele Norcini, Giuseppe Li Bassi, Marco Visconti, Celine Dietlin, Xavier Allonas, Jean Pierre Fouassier
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Publication number: 20080185317Abstract: Froth flotation collectors comprising dithiocarbamates of the Formula (I) as described herein are useful for the beneficiation and recovery of metals from mineral ores.Type: ApplicationFiled: February 7, 2008Publication date: August 7, 2008Inventor: Devarayasamudram R. Nagaraj
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Patent number: 6949574Abstract: The present invention relates to novel oxime carbamyl derivatives and pharmaceutical compositions comprising said derivatives which inhibit fatty acid amide hydrolase. These pharmaceutical compositions are useful for the treatment of conditions which can be effected by inhibiting fatty acid amide hydrolase including, but not limited to, neuropathic pain, emesis, anxiety, altering feeding behaviors, movement disorders, glaucoma, brain injury, and cardiovascular disease.Type: GrantFiled: February 4, 2003Date of Patent: September 27, 2005Assignee: Bristol-Myers Squibb CompanyInventors: Sing-Yuen Sit, Kai Xie, Hongfeng Deng
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Patent number: 6844407Abstract: Control agents that have a nitrogen-nitrogen bond covalently bonded to a thiocarbonyl moiety are provided for living-type free radical polymerization of a wide variety of monomers. These control agents provide superior properties for control of the polymerization and/or the properties of the polymers obtained and/or the monomers that may be polymerized. In some embodiments, a bulky group is pendant off the activated thiocarbonyl portion of the control agents. Multifunctional control agents provide the opportunity for a variety of structurally unique polymers, including block copolymers, stars and hyper-branched polymers.Type: GrantFiled: April 3, 2003Date of Patent: January 18, 2005Assignee: Symyx Technologies, Inc.Inventors: Dominique Charmot, Han Ting Chang, Wenyue Wang
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Patent number: 6825373Abstract: A method of preparing a pyrrolotriazin-4-one and a method of preparing the isothiocyanatoformic acid ester derivative which can be used as a reactant in that method of preparing a pyrrolotriazin-4-one. The method of preparing the pyrrolotriazin-4-one includes an addition step of an aminopyrrole derivative and the isothiocyanatoformic compound and a step of ring-closing reaction of a resulting adduct.Type: GrantFiled: February 14, 2002Date of Patent: November 30, 2004Assignee: Fuji Photo Film Co., Ltd.Inventor: Tetsunori Matsushita
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Publication number: 20040132966Abstract: Thioester and selenoester generators, precursors thereof, thioester and selenoester compounds produced therefrom, and related methods for their production are provided. The subject thioester and selenoester generators include an amino acid synthon having an N-terminal group joined to a C-terminal group through an organic backbone comprising one or more carbons. The organic backbone contains a backbone nitrogen, anchored to a support through a nucleophile-stable linker that lacks reactive functional groups. The organic backbone may include a target molecule of interest, such as an amino acid, peptide, polypeptide or other organic compound of interest, and/or the N- and/or C-termini can be elaborated using a variety of synthesis approaches to provide a target molecule of interest. The compounds and methods find a wide variety of uses, including use in thioester- or selenoester-based chemical ligation techniques.Type: ApplicationFiled: July 18, 2003Publication date: July 8, 2004Inventor: Leslie Philip Miranda
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Publication number: 20030087829Abstract: Disclosed are novel compounds and novel pharmaceutical compositions for use in medical therapy, as well as intermediates and processes for preparing such compounds. Therapeutic methods for preventing or treating glutamate-related disorders in a mammal and methods to inhibit or prevent glutamate binding in mammalian tissue are also disclosed.Type: ApplicationFiled: October 28, 2002Publication date: May 8, 2003Inventors: Morris Faiman, John V. Schloss, Jang-Yen Wu
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Patent number: 6545172Abstract: A process for the production of methyl dithiocarbazinate includes the steps of providing a mixture comprising hydrazine, solvent, carbon disulfide and base; adding methyl bromide to the mixture; cooling the reaction mixture; and recovering methyl dithiocarbazinate. The methyl dithiocarbazinate may be recovered by filtering the reaction mixture to yield a solid methyl dithiocarbazinate retentate and a liquid filtrate; acidifying the filterate with a mineral acid; and adding methyl isobutylketone to the acidified filterate.Type: GrantFiled: April 18, 2002Date of Patent: April 8, 2003Assignee: Bayer CorporationInventors: Vidyanatha A. Prasad, Klaus Jelich, Dennis E. Jackman
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Patent number: 6518448Abstract: Control agents that have a nitrogen-nitrogen bond covalently bonded to a thiocarbonyl moiety are provided for living-type free radical polymerization of a wide variety of monomers. These control agents provide superior properties for control of the polymerization and/or the properties of the polymers obtained and/or the monomers that may be polymerized. In some embodiments, a bulky group is pendant off the activated thiocarbonyl portion of the control agents. Multifunctional control agents provide the opportunity for a variety of structurally unique polymers, including block copolymers, stars and hyper-branched polymers.Type: GrantFiled: September 25, 2001Date of Patent: February 11, 2003Assignee: Symyx Technologies, Inc.Inventors: Han Ting Chang, Dominique Charmot, Yunxiao Li
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Publication number: 20020183384Abstract: The present invention provides a method of treating a disease or a disorder responsive to inhibition of nuclear factor-&kgr;B transcription factors comprising administering to a patient in need thereof a sulfonylaminocarbonyl derivative, or a pharmaceutically acceptable salt thereof. The methods of the present invention are useful for treating, for example, rheumatoid arthritis, osteoarthritis, an autoimmune disease, psoriasis, asthma, a cardiovascular disease, an acute coronary syndrome, congestive heart failure, Alzheimer's disease, multiple sclerosis, cancer, type 2 diabetes, metabolic syndrome X, or inflammatory bowel disease.Type: ApplicationFiled: February 8, 2002Publication date: December 5, 2002Inventors: Joseph Anthony Cornicelli, Sotirios K. Karathanasis
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Patent number: 6465457Abstract: Fungicidal compounds of formula (I): wherein W is CH3O.Type: GrantFiled: August 18, 1994Date of Patent: October 15, 2002Assignee: Zeneca LimitedInventors: Ian Richard Matthews, Christopher Richard Ayles Godfrey, John Martin Clough
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Patent number: 6414158Abstract: The invention relates to novel carbazate intermediates of formula (II), and to a process for their preparation, and their usefulness in the preparation of (1,3,4) oxadiazine derivatives useful as pesticides, in particular as anthelminthicides, insecticides, acaricides, and nematicides.Type: GrantFiled: July 6, 2000Date of Patent: July 2, 2002Assignee: Bayer AKtiengesellschaftInventors: Hubert Dyker, Andrew Plant, Jürgen Scherkenbeck, Christoph Erdelen, Achim Harder
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Patent number: 6124382Abstract: The invention concerns the use as thermothickeners of multi-block copolymers of general formula (I) or (II): ##STR1## wherein E designates a polyoxyalkylene sequence; A designates a water-soluble polymer sequence; X is a sulphur or oxygen atom; Y is an oxygen atom or an --N--R' group, R' being a linear or branched alkyl; R is a linear or branched alkyl, aralky or alkylaryl group; and n is such that the molecular mass of the multi-block copolymers Mp is greater than 250,000 g/mol.Type: GrantFiled: September 8, 1998Date of Patent: September 26, 2000Assignee: Rhodia ChimieInventors: Pascale Corpart, Herve Adam, Dominique Charmot
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Patent number: 6066754Abstract: The present invention provides a process for making N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives by reacting a chloroformate with a thiocyanate, in the presence of an organic solvent and a catalytic amount of a N,N-dialkylarylamine, to produce a N-alkoxy(or aryloxy)carbonyl isothiocyanate intermediate product, wherein the intermediate product is converted to a N-alkoxy(or aryloxy)carbonyl isothiocyanate derivative in high yield and purity.Type: GrantFiled: June 10, 1999Date of Patent: May 23, 2000Assignee: Bayer CorporationInventor: Shekhar V. Kulkarni
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Patent number: 6034096Abstract: The present invention provides medicinal compounds that are characterized by a cyclic moiety (A) linked through a carboxamido group (more specifically, a carbamate group or a urea group) to another cyclic moiety (B) which is in turn linked to another, N-substituted carboxamido group. These compounds can be used an anti-inflammatory and immunosuppressive agents, as demonstrated by their inhibition of the production of IL-1.beta. in vitro and TNF.alpha. in vivo.Type: GrantFiled: November 12, 1998Date of Patent: March 7, 2000Assignee: Italfarmaco S.p.A.Inventors: Giorgio Bertolini, Mauro Biffi, Flavio Leoni, Jacques Mizrahi, Gianfranco Pavich, Paolo Mascagni
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Patent number: 6025514Abstract: Disclosed herein is a process for preparing high yields of methyl dithiocarbazinate by reacting carbon disulfide, hydrazine and a base in an aqueous medium, in an effective ratio to form a dithiocarbazinate salt followed by methylating the dithiocarbazinate salt with methyl bromide.Type: GrantFiled: September 21, 1998Date of Patent: February 15, 2000Assignee: Bayer CorporationInventors: Dennis E. Jackman, David T. Erdman, Peter E. Newallis, Daniel M. Wasleski, Vijay C. Desai, Jeffrey D. Macke, Vidyanatha A. Prasad
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Patent number: 5877339Abstract: Disclosed herein is an aqueous process for preparing high yields of methyl dithiocarbazinate by reacting carbon disulfide and hydrazine in an effective ratio, in an aqueous medium to form hydrazinium dithiocarbazinate salt followed by methylating the hydrazinium dithiocarbazinate with methyl bromide.Type: GrantFiled: November 7, 1996Date of Patent: March 2, 1999Assignee: Bayer CorporationInventors: Daniel M. Wasleski, Peter E. Newallis, Dennis E. Jackman, David T. Erdman, Jeffrey D. Macke, Vidyanatha A. Prasad, Vijay C. Desai
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Patent number: 5861526Abstract: Disclosed herein is an improved process for preparing methyl dithiocarbazinate by reacting carbon disulfide and hydrazine in an effective ratio to form hydrazinium dithiocarbazinate, followed by methylating the hydrazinium dithiocarbazinate with methyl bromide. The improvement resides in conducting the reaction of the carbon disulfide and hydrazine in the presence of a specified amount of a non-alcoholic solvent to reduce dithiocarbazinate buildup.Type: GrantFiled: June 5, 1997Date of Patent: January 19, 1999Assignee: Bayer CorporationInventor: David M. Mayes
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Patent number: 5763489Abstract: A compound of the formula ##STR1## wherein R.sup.1 is carboxy or protected carboxy,R.sup.2 is hydrogen, hydroxy or protected hydroxy,R.sup.3 is hydrogen, hydroxy, protected hydroxy, etc.,R.sup.4 is hydrogen or halogen,A.sup.1 is lower alkylene,A.sup.2 is bond or lower alkylene,--R.sup.5 is ##STR2## (in which R.sup.6 is mono(or di or tri)aryl(lower)alkyl and Z is N or CH), etc., and ##STR3## and a pharmaceutically acceptable salt thereof which are useful as medicaments.Type: GrantFiled: October 10, 1996Date of Patent: June 9, 1998Assignee: Fujisawa Pharmaceutical Co., Ltd.Inventors: Kiyoshi Taniguchi, Masanobu Nagano, Kouji Hattori, Kazunori Tsubaki, Osamu Okitsu, Seiichiro Tabuchi
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Patent number: 5728729Abstract: 3-Methoxy-2-phenyl-acrylic esters of the formula ##STR1## in which R represents optionally substituted alkyl, cycloalkyl or aryl andn represents a number 0 or 1,a process for their preparation and their use as pesticides.Type: GrantFiled: November 13, 1995Date of Patent: March 17, 1998Assignee: Bayer AktiengesellschaftInventors: Herbert Gayer, Peter Gerdes, Heinz-Wilhelm Dehne
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Patent number: 5710256Abstract: The present invention is directed to novel methadone derivatives which are synthesized for the covalent attachment to antigens (proteins or polypeptides) for the preparation of antibodies or receptors to methadone and methadone metabolites. The resulting novel antigens may be used for the production of antibodies or receptors using standard methods. Once generated, the antibodies or receptors and the novel derivatives which are covalently attached to proteins, polypeptides or labels may be used in the immunoassay process.Type: GrantFiled: April 3, 1995Date of Patent: January 20, 1998Assignee: Biosite Diagnostics IncorporatedInventor: Kenneth F. Buechler
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Patent number: 5565602Abstract: A process which can be used for producing thiolcarbamates is provided wherein the process comprises contacting a reaction mixture with a hydrocarbyl chloride such as, for example, benzyl chloride under a condition which is sufficient to produce a product mixture wherein the reaction mixture comprises carbonyl sulfide, an amine such as, for example, a secondary amine, a solvent; the solvent comprises a tertiary amine; and the reaction mixture, hydrocarbyl halide, and solvent are each present in an amount sufficient to effect the production of a thiolcarbamate. Optionally, the reaction mixture can also comprise a metal hydroxide. Further optionally, the product mixture can be contacted with a metal hydroxide if the reaction mixture does not comprise a metal hydroxide.Type: GrantFiled: March 13, 1995Date of Patent: October 15, 1996Assignee: Phillips Petroleum CompanyInventors: Michael S. Matson, Dean E. Stinn, Michael D. Mitchell
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Patent number: 5468896Abstract: The present invention relates to a process for preparation of 5-pyrazolemercaptan derivatives represented by the following general formula (I), which is useful for synthesis of sulfonylurea-based herbicides, and an intermediate thereof, ##STR1## wherein R.sup.1 represents hydrogen, C.sub.1 -C.sub.4 alkyl, allyl or propargyl,R.sup.2 represents hydrogen, C.sub.1 -C.sub.4 alkyl, or a phenyl group which can contain one or more substituent selected from the group consisting of halogen, nitro and methyl at an optional position, andR.sup.3 represents hydrogen, methyl, ethyl or phenyl.Type: GrantFiled: February 10, 1995Date of Patent: November 21, 1995Assignee: Lucky Ltd.Inventors: Jong K. Choi, In B. Jhung, Jae C. Lee, Jong S. Sa, Sung J. Jo, Jin H. Cho
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Patent number: 5466854Abstract: The present invention relates to a process for preparation of 5-pyrazolemercaptan derivatives represented by the following general formula (I), which is useful for synthesis of sulfonylurea-based herbicides, and an intermediate thereof, ##STR1## wherein R.sup.1 represents hydrogen, C.sub.1 -C.sub.4 alkyl, allyl or propargyl,R.sup.2 represents hydrogen, C.sub.1 -C.sub.4 alkyl, or a phenyl group which can contain one or more substituent selected from the group consisting of halogen, nitro and methyl at an optional position, andR.sup.3 represents hydrogen, methyl, ethyl or phenyl.Type: GrantFiled: February 10, 1995Date of Patent: November 14, 1995Assignee: Lucky Ltd.Inventors: Jong K. Choi, In B. Jhung, Jae C. Lee, Jong S. Sa, Sung J. Jo, Jin H. Cho
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Patent number: 5459149Abstract: The present Application discloses pesticidally active compounds of formula (I):Q(CH.sub.2).sub.a (O).sub.b Q.sup.1 CR.sup.2 =CR.sup.3 CR.sup.4 =CR.sup.5 CXNR.sup.1 R.sup.xor a salt or propesticide thereof, wherein Q is an optionally substituted aromatic monocyclic or fused bicyclic ring system in which at least one ring is aromatic, or Q is a dihalovinyl group or a group R.sup.6 --C=C--where R.sup.6 is C.sub.1-4 alkyl, tri C.sub.1-4 alkylsilyl, halo or hydrogen; Q.sup.1 is a 1,2-cyclopropyl ring optionally substituted by one or more groups selected from C.sub.1-3 alkyl, halo, C.sub.1-3 haloalkyl, C.sub.2-3 alkynyl, or cyano; or Q.sup.1 is (CH.sub.2).sub.7 ; a=0 or 1; b=0 or 1; R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are the same or different with at least one being hydrogen and the others being independently selected from hydrogen, halo, C.sub.1-4 alkyl or C.sub.1-4 haloalkyl; X is oxygen or sulphur;R.sup.1 is phenyl optionally substituted by 1-5 substituents chosen from: a) C.sub.1-4 alkyl, C.sub.Type: GrantFiled: September 20, 1994Date of Patent: October 17, 1995Assignee: Roussel UclafInventors: John E. Robinson, George S. Cockerill
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Patent number: 5416220Abstract: The present invention relates to a process for preparation of 5-pyrazolemercaptan derivatives represented by the following general formula (I), which is useful for synthesis of sulfonylurea-based herbicides, and an intermediate thereof, ##STR1## wherein R.sup.1 represents hydrogen, C.sub.1 -C.sub.4 alkyl, allyl or propargyl,R.sup.2 represents hydrogen, C.sub.1 -C.sub.4 alkyl, or a phenyl group which can contain one or more substituent selected from the group consisting of halogen, nitro and methyl at an optional position, andR.sup.3 represents hydrogen, methyl, ethyl or phenyl.Type: GrantFiled: November 15, 1994Date of Patent: May 16, 1995Assignee: Lucky, Ltd.Inventors: Jong K. Choi, In B. Jhung, Jae C. Lee, Jong S. Sa, Sung J. Jo, Jin H. Cho
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Patent number: 5354495Abstract: A physical property-improving reagent which comprises an alkenoylcarbamate compound of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group, X is an oxygen atom (--O--), a sulfur atom (--S--) or a substituted or unsubstituted imino group (--NR'--), R' being a hydrogen atom or a lower alkyl group, and Y is the residue of an active hydrogen atom-containing compound excluding --X--H therefrom dissolved in an organic solvent having a solubility parameter of not less than 8, which can impart excellent physical properties to a polymer produced with the same.Type: GrantFiled: March 1, 1990Date of Patent: October 11, 1994Assignee: Nippon Paint Co., Ltd.Inventors: Satoshi Urano, Ryuzo Mizuguchi, Noriyuki Tsuboniwa, Kei Aoki, Yuji Suzuki, Takeyasu Itoh
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Patent number: 5334748Abstract: Fungicidal compounds of the formula (I): ##STR1## and stereoisomers thereof, wherein K is oxygen or sulphur; Z is optionally substituted aryl or optionally substituted heteroaryl; X is O, S(O).sub.n, NR.sup.4, CR.sup.1 R.sup.2 CHR.sup.5, CO, CR.sup.1 (OR.sup.2), C.dbd.CR.sup.1 R.sup.2, CHR.sup.1 CHR.sup.2, CR.sup.1 .dbd.CR.sup.2, CHR.sup.1 CR.sup.2 .dbd.CH, C.tbd.C, OCHR.sup.1, CHR.sup.1 O, OCHR.sup.1 O, S(O).sub.n CHR.sup.1 S(O).sub.n CHR.sup.1 O, CHR.sup.1 S(O).sub.n, CHR.sup.1 OSO.sub.2, NR.sup.4 CHR.sup.1, CHR.sup.1 NR.sup.4, CO.sub.2, O.sub.2 C, SO.sub.2 O, OSO.sub.2, CO.CO, COCHR.sup.1, COCHR.sup.1 O, CHR.sup.1 CO, CHOH.CHR.sup.1, CHR.sup.1.CHOH ##STR2## CONR.sup.4, OCONR.sup.4, NR.sup.4 CO, CSNR.sup.4, OCS.NR.sup.4, SCO.NR.sup.4, NR.sup.4 CO.sub.2, NR.sup.4 CS, NR.sup.4 CSO, NR.sup.4 COS, NR.sup.4 CONR.sup.4, S(O).sub.n NR.sup.4, NR.sup.4 S(O).sub.n, CS.sub.2, S.sub.2 C, CO.S, SCO, N.dbd.N, N.dbd.CR.sup.1, CR.sup.1 .dbd.N, CHR.sup.1 CHR.sup.2 CH(OH), CHR.sup.1 OCO, CHR.sup.1 SCO, CHR.sup.1 NR.sup.Type: GrantFiled: September 9, 1988Date of Patent: August 2, 1994Assignee: Imperial Chemical Industries PLCInventors: Alan J. Buckley, Michael G. Huchings, Ian Ferguson, Kevin Beautement, John M. Clough, Patrick J. Crowley, Christopher R. A. Godfrey, Paul J. deFraine, Vivienne M. Anthony, Stephen P. Heaney
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Patent number: 5254715Abstract: A compound of the following general formula which is useful in treating hypocholesterolemia and atherosclerosis: ##STR1## wherein X is oxygen or sulfur; R is hydrogen, alkyl having from 1 to 8 carbon atoms, or benzyl; R.sub.1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, an aralkyl group, a heterocyclic group, or a hydrocarbon chain of from 1 to 20 carbon atoms which is saturated or contains 1 to 3 double bonds and each of R.sub.2 and R.sub.3 is selected from hydrogen, provided both are not hydrogen, an aralkyl group, a hydrocarbon chain of from 1 to 20 carbon atoms which is saturated or contains 1 to 3 double bonds, an w-substituted alkylC.sub.1-6, a heterocyclic group, phenyl, substituted phenyl or NR.sub.2 R.sub.3 taken together form a monocyclic heterocyclic group.Type: GrantFiled: August 19, 1991Date of Patent: October 19, 1993Assignee: Warner-Lambert CompanyInventors: Joseph A. Picard, Drago R. Sliskovic
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Patent number: 5247087Abstract: Dithiocarbamic salts made from the reaction products of certain polyamines and epoxides have been found to be useful to clarify water, particularly the oil-in-water emulsions which accompany crude oil production. The water clarification may be accomplished by demulsification or flocculation. The polyamine reaction products themselves are novel and may have the structure ##STR1## where R" is selected from the group consisting of the structure --R--NH.sub.2 and ##STR2## where R is selected from the group consisting of straight, branched or cyclic alkylene moieties; arylene moieties; substituted straight, branched or cyclic alkylene moieties; substituted arylene moieties or mixtures thereof; and where R' is--(CH.sub.2).sub.m --O--R--O--(CH.sub.2).sub.m --where n and m independently range from 1 to 5 and q is 0 or 1. The dithiocarbamic salts made from these polyamines also find use as corrosion inhibitors.Type: GrantFiled: May 13, 1992Date of Patent: September 21, 1993Assignee: Baker Hughes IncorporatedInventor: Gordon T. Rivers
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Patent number: 5245071Abstract: Compounds of the formula ##STR1## wherein A is a hydrogen atom, a halogen atom, a methyl group, or a methoxy group;B is a hydrogen atom, a halogen atom, a methyl group, or a methoxy group, with the proviso that A and B ar not both a hydrogen atom;X and Y each are an oxygen atom or a sulfur atom;R is a hydrogen atom, an alkyl group, a hydroxy group, an alkoxy group, an alkoxymethyl group, an acyl group, or an alkoxycarbonyl group;R.sub.1 is a hydrogen atom, an alkyl group, a halogen substituted alkyl group, an alkoxy substituted alkyl group, an alkylthio substituted alkyl group, a cyano substituted alkyl group, a 1-cycloalkenyl group, a benzyl group, a halogen substituted benzyl group, a hydroxy group, an alkoxy group, an acyl group, an alkoxycarbonyl group, an alkoxythiocarbonyl group, an alkylsulfonyl group, or a phenylsulfonyl group, while furthermore R and R.sub.1 together with the group ##STR2## indicated in the above formula may form a ring system; and R.sub.Type: GrantFiled: June 3, 1992Date of Patent: September 14, 1993Assignee: Duphar International Research B.V.Inventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 5189058Abstract: The compounds of the present invention have the formula ##STR1## wherein each of X and Y is oxygen or sulfur, R is hydrogen or lower alkyl, and each of R.sub.1 and R.sub.2 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, aralkyl, a hydrocarbon chain, a hetero group, or a heteroalkyl group, and the compounds are useful in treating atherosclerosis.Type: GrantFiled: April 9, 1991Date of Patent: February 23, 1993Assignee: Warner-Lambert CompanyInventors: Helen T. Lee, Joseph A. Picard, Drago R. Sliskovic
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Patent number: 5024691Abstract: As new compounds, substituted aryloxyphenoxy benzamides having the formula ##STR1## in which X is CH or nitrogen; Y is chlorine, bromine, fluorine, iodine, methyl, cyano or hydrogen; Z is hydrogen, chlorine, bromine, fluorine, iodine, CH.sub.n, F.sub.3-n where n is an integer from 0 to 3; R is nitrogen dioxide, hydrogen or halogen; R' is hydrogen, CH.sub.3, lower alkyl, having 1-10 carbon atoms, SCCl.sub.3, ##STR2## or --PO.sub.3 R.sup.3.sub.2 wherein R.sup.3 is hydrogen, alkyl having 1-10 carbon atoms, aryl, or an equivalent of base such as a salt; R" is cyano, --C.tbd.CH, ##STR3## wherein R.sup.4 is hydrogen, alkyl having 1-10 carbon atoms, aryl or an equivalent of base such as a salt; and m is 0, 1, 2 or 3.Type: GrantFiled: August 4, 1986Date of Patent: June 18, 1991Assignee: ICI Americas Inc.Inventor: Sreeramulu Nagubandi
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Patent number: 5017604Abstract: The present invention is novel selected hydroxamic acid derivatives of fenamic acids having 5-lipoxygenase and cyclooxygenase inhibiting properties, pharmaceutical compositions for treating conditions advantageously affected by the inhibition and methods for treating these conditions in mammals, including humans suffering therefor.Type: GrantFiled: April 11, 1990Date of Patent: May 21, 1991Assignee: Warner-Lambert CompanyInventors: Thomas R. Belliotti, Catherine R. Kostlan
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Patent number: 5010104Abstract: Novel tricyclic compounds having a TXA.sub.2 -antagonizing activity represented by formul (I): ##STR1## which strongly antagonize an action of thromboxane A.sub.2 and are expected to have preventive and therapeutic effects on ischemica diseases, cerebro-vascular diseases, etc.Type: GrantFiled: June 29, 1989Date of Patent: April 23, 1991Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Etsuo Oshima, Hiroyuki Obase, Akira Karasawa, Kazuhiro Kubo, Ichiro Miki, Akio Ishii
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Patent number: 4935413Abstract: A physical property-improving reagent which comprises an alkenoylcarbamate compound of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group, X is an oxygen atom (--O--), a sulfur atom (--S--) or a substituted or unsubstituted imino group (--NR'--), R' being a hydrogen atom or a lower alkyl group, and Y is the residue of an active hydrogen atom-containing compound excluding --X-H therefrom dissolved in an organic solvent having a solubility parameter of not less than 8, which can impact excellent physical properties to a polymer produced with the same.Type: GrantFiled: June 5, 1987Date of Patent: June 19, 1990Assignee: Nippon Paint Co., Ltd.Inventors: Satoshi Urano, Ryuzo Mizuguchi, Noriyuki Tsuboniwa, Kei Aoki, Yuji Suzuki, Takeyasu Itoh
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Patent number: 4931580Abstract: Aryl sulfonylureas as new compositions and included in a two-part herbicide system comprising at least one or more thiolcarbamate, thiolcarbamate sulfoxide or haloacetanilide herbicide, and as the second part a non-phytotoxic antidotally effective amount of aryl sulfonylurea as an antidote therefor of the formula ##STR1## in which X is oxygen or sulfur; n is an integer; R is lower alkyl, lower alkoxy, lower alkylthio, halogen, trifluoromethyl, cyano, nitro, lower alkyl sulfonyl;R.sup.4 is hydrogen, lower alkyl, lower alkoxyalkyl, phenyl and chlorophenyl;R.sup.2 is hydrogen, lower alkyl, alkoxyalkyl and phenyl;R.sup.1 is lower alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, 1-phenylpropenyl, benzyl, chlorobenzyl, haloalkenyl, phenyl and alkyl substituted phenyl; andAR is phenyl, benzyl, naphthyl, pyridyl or styryl; and the inorganic base salts sodium, potassium, ammonium and other inorganic salts; and organic base salts thereof.Type: GrantFiled: December 23, 1983Date of Patent: June 5, 1990Inventors: Ferenc M. Pallos, Kang-Chi Lin, Laddie L. Green
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Patent number: 4728670Abstract: Biphenyl hydroxamic acids are provided having the structure ##STR1## wherein m is 1 to 7, X is S, O or NH, R is H, lower alkyl, aryl, aralkyl or cycloalkyl and R.sup.1 is H, lower alkyl, aryl, aralkyl, cycloalkyl, alkanoyl or aroyl.These compounds are inhibitors of .DELTA..sup.5 -lipoxygenase and as such are useful as antiallergy agents.Type: GrantFiled: June 4, 1986Date of Patent: March 1, 1988Assignee: E. R. Squibb & Sons, Inc.Inventors: Martin F. Haslanger, Ravi K. Varma, Eric M. Gordon
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Patent number: 4697033Abstract: Certain novel derivatives of carbamates and their use for the control of pests.Type: GrantFiled: December 24, 1985Date of Patent: September 29, 1987Assignee: Sandoz Ltd.Inventor: Clive A. Henrick
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Patent number: 4668800Abstract: There is described a process for producing sulfonylureas of the formula ##STR1## wherein G is an unsubstituted or substituted furanyl, thienyl, pyrrolyl, pyridinyl or phenyl radical,X is alkyl, haloalkyl, alkoxy, alkylthio, halogen, haloalkoxy, alkylamino or dialkylamino,Y is alkyl, alkoxy or haloalkoxy,Z is a nitrogen atom or the methyne group --CH.dbd..This novel process comprises reacting a sulfonamide of the formulaG--SO.sub.2 --NH.sub.2,in the presence of a base, with a chloroformic acid ester of the formulaCl--CO--Q--T,or a sulfonyl chloride of the formulaG--SO.sub.2 Cl,in the presence of a base, with a urethane of the formulaH.sub.2 N--CO--Q--T;and converting the formed carbamate of the formulaG--SO.sub.2 --NH--CO--Q--Tby reaction with an amine of the formula ##STR2## into the sulfonylurea of the above formula. There are also described novel sulfonylcarbamates of the above formula as intermediates.Type: GrantFiled: March 4, 1985Date of Patent: May 26, 1987Assignee: Ciba-Geigy CorporationInventors: Willy Meyer, Werner F/o/ ry, Werner T/o/ pfl
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Patent number: 4659853Abstract: Derivatives of alkoxy, aryloxy and alkene isothiocyanates are produced by the reaction of a haloformate, an alkali, alkaline earth metal, lead or ammonium thiocyanate and a compound having the formula R.sup.1 YH wherein R.sup.1 is alkyl, aryl or alkoxy, Y is oxygen, sulfur or NR.sup.2 and R.sup.2 is hydrogen or R.sup.1, in the presence of a solvent or water and a catalyst.Type: GrantFiled: January 22, 1986Date of Patent: April 21, 1987Assignee: American Cyanamid CompanyInventors: Yun-Lung Fu, Peter J. Strydom
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Patent number: 4658025Type: GrantFiled: December 21, 1984Date of Patent: April 14, 1987Assignee: Bayer AktiengesellschaftInventor: Fritz Maurer
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Patent number: 4584097Abstract: New and improved collector compositions for use in froth flotation processes for the beneficiation of mineral values from base metal sulfide ores are disclosed. The collector compositions comprise at least one hydrocarboxycarbonyl thionocarbamate compound selected from compounds of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each, independently, selected from saturated and unsaturated hydrocarbyl radicals, alkyl polyether radicals and aromatic radicals, or such radicals optionally substituted by polar groups selected from halogen, nitrile and nitro groups. The use of the hydrocarboxycarbonyl thionocarbamate collectors provides excellent metallurgical recoveries of sulfide mineral values in froth flotation processes conducted over a broad range of pH conditions including acid, neutral and mildly alkaline pH.Type: GrantFiled: August 17, 1984Date of Patent: April 22, 1986Assignee: American Cyanamid CompanyInventors: Yun-Lung Fu, Samuel S. Wang
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Patent number: 4581175Abstract: N'-Acylhydrazine-N-thiocarboxylic acid O-carbamoylmethyl esters of the formula ##STR1## in which R.sup.1 is alkyl, alkoxy, alkylthio, halogenoalkyl, aralkyl, aralkoxy, aralkylthio or optionally substituted aryl, andR.sup.2 and R.sup.3 each independently is hydrogen, alkyl, alkenyl, alkinyl, optionally substituted cycloalkyl or cycloalkenyl, halogenoalkyl, alkoxyalkyl, alkoxy, aralkyl or optionally substituted aryl, orR.sup.2 and R.sup.3, together with the nitrogen atom to which they are bonded, are an optionally substituted heterocyclic radical,are new compounds useful in preparing known thiadiazole herbicides in high yield by ring closure.Type: GrantFiled: December 21, 1984Date of Patent: April 8, 1986Assignee: Bayer AktiengesellschaftInventor: Fritz Maurer