Nitrogen Or Additional Chalcogen Attached Indirectly To The Nitrogen By Acyclic Nonionic Bonding Patents (Class 558/239)
-
Publication number: 20130177961Abstract: Multi-armed, monofunctional, and hydrolytically stable polymers are described having the structure wherein Z is a moiety that can be activated for attachment to biologically active molecules such as proteins and wherein P and Q represent linkage fragments that join polymer arms polya and polyb, respectively, to central carbon atom, C, by hydrolytically stable linkages in the absence of aromatic rings in the linkage fragments. R typically is hydrogen or methyl, but can be a linkage fragment that includes another polymer arm. A specific example is an mPEG disubstituted lysine having the structure where mPEGa and mPEGb have the structure CH3O—(CH2CH2O)nCH2CH2— where n may be the same or different for polya- and polyb- and can be from 1 to about 1,150 to provide molecular weights of from about 100 to 100,000.Type: ApplicationFiled: December 14, 2012Publication date: July 11, 2013Applicant: NEKTAR THERAPEUTICSInventor: NEKTAR THERAPEUTICS
-
Publication number: 20130090443Abstract: Carbamate and thiocarbamate compounds are described that comprise a polymerizable moiety and one or more free hydroxyl and/or thiol groups. Polymers may be obtained by polymerizing these carbamate and/or thiocarbamate compounds. The carbamate and thiocarbamate compounds, as well as the polymers they produce may be formulated into adhesive, agricultural, biocide, cleaning, coating, encapsulation, membrane, oilfield, performance chemical, and personal care compositions.Type: ApplicationFiled: June 22, 2011Publication date: April 11, 2013Applicant: ISP Investments Inc.Inventor: Osama M. Musa
-
Patent number: 8106141Abstract: Reaction products prepared from reactants including: (a) at least one compound of structural Formula (I): wherein R1 is selected from aryl and heteroaryl; X is selected from a direct bond, —O—, —S—, —NH—, alkylene, cycloalkylene, heterocyclylene, arylene, alkarylene, and heteroarylene; Y is a substituted alkylene group having at least two contiguous carbon atoms and which can be interrupted by one or more —O—, —S—, or —NH— moieties as defined herein, wherein the alkylene group of Y has substituents independently selected from —OH, —NH2, —SH, cycloalkyl, heterocyclyl, aryl, and heteroaryl, or two hydrogen atoms on the same carbon atom of Y are replaced by carbonyl, and wherein at least two substituents of Y are each independently selected from —OH, —NH2, and —SH, as defined herein; and (b) at least one isocyanate functional material.Type: GrantFiled: May 7, 2008Date of Patent: January 31, 2012Assignee: Henkel CorporationInventors: Anthony F. Jacobine, Andrew Messana, David M. Glaser, Steven Thomas Nakos
-
Patent number: 7192965Abstract: Compounds of formula wherein A1, A2 and A3 are each independently of the others a bond or a C1–C6alkylene bridge; A4 is a C1–C6alkylene bridge; D is CH or N; W is, for example, O, NR7 or S; T is, for example, a bond, O, NH or NR7; Q is O, NR7, S, SO or SO2; Y is O, NR7, S, SO or SO2; X1 and X2 are each independently of the other fluorine, chlorine or bromine; R1, R2 and R3 are, for example, H, halogen, CN, nitro, C1–C6alkyl, C1–C6haloalkyl, C1–C6alkylcarbonyl or C2–C6alkenyl; R4 is, for example, H, halogen, CN, nitro or C1–C6alkyl; R5 and R6 are, for example, H, CN, OH, C1–C6alkyl, C3–C8cycloalkyl, C3–C8cycloalkyl-C1–C6alkyl, C1–C6haloalkyl, C1–C6alkoxy or C1–C6haloalkoxy; R7 is H, C1–C6alkyl, C1–C6alkoxyalkyl or C1–C6alkylcarbonyl; k, when D is nitrogen, is 1, 2 or 3; or, when D is CH, is 1, 2, 3 or 4; and m is 1 or 2; and, where applicable, their possible E/Z isomers, E/Z isomeric mixtures and/or tautomers, in each case in free form or in salt form, a process for the preparation of those compounds andType: GrantFiled: June 27, 2003Date of Patent: March 20, 2007Assignee: Syngenta Crop Protection, Inc.Inventors: Werner Zambach, Peter Renold, Arthur Steiger, Stephan Trah, Roger Graham Hall
-
Patent number: 7112558Abstract: The invention relates to a lubricating composition comprising a base oil of lubricating viscosity, a hydroxy-substituted dithiocarbamate, an organo-molybdenum compound, and optionally a phosphorous source.Type: GrantFiled: February 8, 2002Date of Patent: September 26, 2006Assignee: Afton Chemical Intangibles LLCInventor: Vincent J. Gatto
-
Patent number: 6852680Abstract: This invention relates to a low cost, wear inhibitor containing novel dithiocarbamates with alkylthio and hydroxy substituents that can be used to formulate low phosphorus lubricants. In addition to wear inhibition, the dithiocarbamate compositions of the invention provide substantial oxidation protection to lubricating oils and are not detrimental to fuel economy.Type: GrantFiled: October 26, 2001Date of Patent: February 8, 2005Assignee: Ethyl CorporationInventor: Vincent James Gatto
-
Publication number: 20030139301Abstract: This invention relates to a low cost, wear inhibitor containing novel dithiocarbamates with alkylthio and hydroxy substituents that can be used to formulate low phosphorus lubricants. In addition to wear inhibition, the dithiocarbamate compositions of the invention provide substantial oxidation protection to lubricating oils and are not detrimental to fuel economy.Type: ApplicationFiled: October 26, 2001Publication date: July 24, 2003Inventor: Vincent James Gatto
-
Patent number: 5952386Abstract: The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.10 alkyl or the like; L is C(.dbd.O)NH or the like; R.sub.2, R.sub.3 and R.sub.4 are independently halogen or the like; R.sub.5, R.sub.6 and R.sub.7 are independently hydrogen or the like; m is an integer of 0 to 4; n is an integer of 0 to 2; X is chlorine or the like; Y is oxygen or the like; and Z is oxygen or the like, which have excellent insecticidal activity so that they are satisfactorily effective for the control of noxious insects.Type: GrantFiled: September 24, 1997Date of Patent: September 14, 1999Assignee: Sumitomo Chemical Company, LimitedInventors: Sanshiro Matsuo, Taro Hirose, Keiichi Izumi, Masaya Suzuki, Noriyasu Sakamoto, Kazunori Tsushima, Shigeru Saito, Hirotaka Takano
-
Patent number: 5811579Abstract: The present invention relates to a method of synthesizing a 2-substituted nitrogen containing compound having a formula (I): ##STR1## by reacting a hydroxylamine of formula (II); ##STR2## or a nitrone of formula (III): ##STR3## with a compound of formula (IV); ##STR4## thereby to form an intermediate compound, and thereafter causing or allowing said intermediate compound to undergo a pericyclic sigmatropic rearrangement reaction to form the compound (I); wherein X is a nucleofugal group, Y is selected from O,S,NH,NR.sub.5 and CR.sub.6 R.sub.7, R.sub.1 is a group which directs the reactivity of compound (II) on to the oxygen atom and R.sub.2 to R.sub.9 are each a substituted or unsubstituted aliphatic, aromatic, heteroaryl or cyclic group or hydrogen which is substantially inert or is protected during the reaction.Type: GrantFiled: May 7, 1997Date of Patent: September 22, 1998Assignee: Eastman Kodak CompanyInventor: John DeMita Goddard
-
Patent number: 5565602Abstract: A process which can be used for producing thiolcarbamates is provided wherein the process comprises contacting a reaction mixture with a hydrocarbyl chloride such as, for example, benzyl chloride under a condition which is sufficient to produce a product mixture wherein the reaction mixture comprises carbonyl sulfide, an amine such as, for example, a secondary amine, a solvent; the solvent comprises a tertiary amine; and the reaction mixture, hydrocarbyl halide, and solvent are each present in an amount sufficient to effect the production of a thiolcarbamate. Optionally, the reaction mixture can also comprise a metal hydroxide. Further optionally, the product mixture can be contacted with a metal hydroxide if the reaction mixture does not comprise a metal hydroxide.Type: GrantFiled: March 13, 1995Date of Patent: October 15, 1996Assignee: Phillips Petroleum CompanyInventors: Michael S. Matson, Dean E. Stinn, Michael D. Mitchell
-
Patent number: 5560853Abstract: A borate ester having the formula ##STR1## wherein Y is N, S or O, X is O or S, R.sup.1 and R.sup.2 are, independent of one another, selected from the group consisting of H, (C.sub.1 -C.sub.40)hydrocarbon residues and (C.sub.3 -C.sub.50)cycloalkyl, aryl and aralkyl, each of which may further contain N, O or S, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are independent of one another, selected from the group consisting of H and (C.sub.1 -C.sub.8)hydrocarbon residues, n is 0 to 4. An anti-wear/anti-oxidant/anti-friction/anti-rust additive comprises the borate ester of the invention when added to a lubricating oil.Type: GrantFiled: March 13, 1992Date of Patent: October 1, 1996Assignee: Pennzoil Products CompanyInventor: I-Ching Chiu
-
Patent number: 5476944Abstract: The present invention relates to derivatives of cyclic phenolic thioethers of the formula: ##STR1## and the pharmaceutically acceptable salts thereof, which are inhibitors or stimulators of superoxide generation, and which may also inhibit cyclooxygenase and/or 5-lipoxygenase, to pharmaceutical compositions containing one or more of these compounds in combination with a pharmaceutically-acceptable carrier, and to medical methods of treatment employing these compounds.Type: GrantFiled: May 19, 1994Date of Patent: December 19, 1995Assignee: G. D. Searle & Co.Inventors: Richard A. Partis, Richard A. Mueller, Francis J. Koszyk, Richard M. Weier
-
Patent number: 5430172Abstract: A process for preparing 4-alkanoylaryl benzyl ethers of the general formula I ##STR1## where R is hydrogen, halogen, cyano; alkyl, alkoxy;X is CH.sub.2, CH--CH.sub.3, CH--CH.sub.2 --CH.sub.3, CH--OCH.sub.3 or N--OCH.sub.3 ;Y is oxygen, sulfur, direct linkage or nitrogen;m is 0, 1, 2 or 3;R.sup.1 is hydrogen; alkyl, alkenyl, alkynyl or alkoxy;R.sup.2 is cyano, halogen, alkyl, alkoxy or haloalkyl;R.sup.3 is alkyl; haloalkyl; cycloalkyl; or an unsubstituted or substituted mono- to trinuclear aromatic system,comprises reacting an aryl benzyl ether of the general formula II ##STR2## where X, Y, R, R.sup.1, R.sup.2 and m have the abovementioned meanings, with a carbonyl halide or with a carboxylic anhydride or with a carboxylic sulfonic anhydride in the presence of an acid and in the presence or absence of a diluent.Type: GrantFiled: April 15, 1994Date of Patent: July 4, 1995Assignee: BASF AktiengesellschaftInventors: Wassilios Grammenos, Wolfgang Siegel, Klaus Oberdorf, Bernd Mueller, Hubert Sauter, Reinhard Doetzer
-
Patent number: 5260439Abstract: The present invention relates to a high surface hardness transparent resin having excellent scratch resistance, heat resistance and chemical resistance, a glazing material, a protective cover for display devices, an optical lens and a hard coat material comprising the aforesaid resin, and a novel polymerizable monomer which is useful as a raw material of the above-mentioned resin.The monomer is represented by the formula (I) ##STR1## (wherein R is an aliphatic residue having or not having an halogen atom, an oxygen atom, an alicyclic ring, a heterocyclic ring or an aromatic ring, an alicyclic residue, or a heterocyclic residue, n is an integer of 1 to 4, when n=1, X is oxygen or sulfur, when n.gtoreq.2, X's are all oxygen or all sulfur, one X is oxygen while the other X or X's are sulfur, one X is sulfur while the other X or X's are oxygen, or two X's are oxygen while the other X's are sulfur).Type: GrantFiled: December 16, 1991Date of Patent: November 9, 1993Assignee: Mitsui Toatsu Chemicals, IncorporatedInventors: Toshiyuki Suzuki, Katsuyoshi Sasagawa, Masao Imai, Yoshinobu Kanemura
-
Patent number: 5152927Abstract: A Mannich reaction of a polyfunctional amine followed by dithiocarbamate formation produces a composition useful as a water clarifier.Type: GrantFiled: January 31, 1990Date of Patent: October 6, 1992Assignee: Chemlink, Inc.Inventor: Gordon T. Rivers
-
Patent number: 5037991Abstract: Substituted phenoxy, phenylthio and anilino compounds, intermediates therefor, synthesis thereof, and their use for the control of pests.Type: GrantFiled: October 3, 1990Date of Patent: August 6, 1991Assignee: Sandoz Ltd.Inventor: Clive A. Henrick
-
Patent number: 5010104Abstract: Novel tricyclic compounds having a TXA.sub.2 -antagonizing activity represented by formul (I): ##STR1## which strongly antagonize an action of thromboxane A.sub.2 and are expected to have preventive and therapeutic effects on ischemica diseases, cerebro-vascular diseases, etc.Type: GrantFiled: June 29, 1989Date of Patent: April 23, 1991Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Etsuo Oshima, Hiroyuki Obase, Akira Karasawa, Kazuhiro Kubo, Ichiro Miki, Akio Ishii
-
Patent number: 4968829Abstract: Substituted phenoxy, phenylthio and anilino compounds, intermediates therefor, synthesis thereof, and their use for the control of pests.Type: GrantFiled: June 19, 1989Date of Patent: November 6, 1990Assignee: Sandoz Ltd.Inventor: Clive A. Henrick
-
Patent number: 4836942Abstract: Compounds or mixtures of compounds having the formulae: ##STR1## wherein R is an alkyl group containing from 1 to 20 carbon atoms, n represents a number selected from the class consisting of zero and the integers from 1 through 6, R' represents a member selected from the group consisting of the hydrogen atom and those groups represented by R and R" is an aliphatic hydrocarbon group are effective antiwear and antioxidant additives in lubricating oils.Type: GrantFiled: June 6, 1988Date of Patent: June 6, 1989Assignee: Ethyl Petroleum Additives, Inc.Inventor: William Y. Lam
-
Patent number: 4788287Abstract: A high performance water and oil repellant composed of a compound comprising at least two terminal segments and an intermediate segment connecting the terminal segments and having a molecular weight of from 800 to 20,000, each terminal segment containing at least one polyfluoroalkyl group connected by a --CONH-- linking group, said intermediate segment being a urethane oligomer containing at least two --CONH-- linking groups in one molecule, and said terminal segments and intermediate segment being connected by a --CONH-- linking group.Type: GrantFiled: September 3, 1986Date of Patent: November 29, 1988Assignee: Asahi Glass Company Ltd.Inventors: Masashi Matsuo, Masayuki Tamura, Katsuji Ito
-
Patent number: 4752615Abstract: A compound of the formula: ##STR1## useful as a fungicidal agent against phytopathogenic fungi, particularly their strains resistant to benzimidazole, thiophanate and/or cyclic imide fungicides.Type: GrantFiled: November 13, 1986Date of Patent: June 21, 1988Assignee: Sumitomo Chemical Company, LimitedInventors: Junya Takahashi, Toshiro Kato, Hiroshi Noguchi, Yukio Oguri, Shigeo Yamamoto, Katsuzo Kamoshita
-
Patent number: 4737518Abstract: Novel lipid derivatives of the formula ##STR1## [wherein R.sup.1 is alkyl or alkylcarbamoyl; R.sup.2 is hydrogen, hydroxy which may be substituted, amino which may be substituted or cyclic amino; R.sup.3 is a chemical binding or alkylene which may be substituted; R.sup.4 is hydrogen, alkyl or aralkyl; X and Y are independently O, S or an imino group which may be substituted, and when Y is an imino group, Y, together with the imino group represented by X or R.sup.4, may form a ring; and Z is imino or a nitrogen-containing heterocyclic ring which may be substituted] and salts thereof have inhibiting activity on platelet activating factor and are useful as a preventive or therapeutic agent for a variety of circulatory diseases and allergic disorders and also as an antineoplastic agent.Type: GrantFiled: September 12, 1986Date of Patent: April 12, 1988Assignee: Takeda Chemical Industries, Ltd.Inventors: Hiroaki Nomura, Kohei Nishikawa, Susumu Tsushima, Yoshio Kozai
-
Patent number: 4710514Abstract: A compound of the formula: ##STR1## useful as a fungicidal agent against phytopathogenic fungi, particularly their strains resistant to benzimidazole, thiophanate and/or dicarboximide fungicides.Type: GrantFiled: April 26, 1983Date of Patent: December 1, 1987Assignee: Sumitomo Chemical Company, LimitedInventors: Junya Takahashi, Toshiro Kato, Katsuzo Kamoshita
-
Patent number: 4692455Abstract: Compounds of the formula ##STR1## wherein Y is oxygen or sulfur are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definition of R.sub.1 may also be useful as analgesics due to their enkepahlinase inhibition activity.Type: GrantFiled: January 25, 1985Date of Patent: September 8, 1987Assignee: E. R. Squibb & Sons, Inc.Inventor: Eric M. Gordon
-
Patent number: 4618461Abstract: The invention relates to novel O,O'-, O,S'- or S,S'-dithiodialkylene-bis(mono- or dihydrocarbyl carbamothioates) and S,S'-dithiodialkylene-bis(mono- or dihydrocarbyl carbamodithioate). The novel compounds of this invention are useful as collectors in the froth flotation of sulfide mineral ores.Type: GrantFiled: July 25, 1983Date of Patent: October 21, 1986Assignee: The Dow Chemical CompanyInventors: Roger W. Bergman, Harry A. Smith
-
Patent number: 4613461Abstract: The invention relates to a new process for preparing known thiolcarbamate esters of the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2 stand independently for hydrogen or a straight or branched chain alkyl group containing 1 to 6 carbon atoms or an alkenyl group containing 2 to 6 atoms, or an alkyl group containing 1 to 6 or an alkenyl group containing 2 to 6 carbon atoms and mono- or polysubstituted by halogen, oxygen, sulphur and/or nitrogen; orR.sup.1 and R.sup.2 together may represent an optionally substituted .alpha.,.omega.-alkylene group containing 4 to 6 carbon atoms;R.sup.3 and R.sup.4 stand independently for hydrogen or an alkyl group containing 1 to 4 carbon atoms and optionally substituted by halogen or by a group containing oxygen, sulphur and/or nitrogen; andR.sup.5 and R.sup.6 both stand for hydrogen; orR.sup.5 and R.sup.6 together may represent a chemical bond.Type: GrantFiled: December 31, 1984Date of Patent: September 23, 1986Assignees: MTA Kozponti Kemiai Kutato Intezet, Borsodi Vegyi KombinatInventors: Peter Viski, Laszlo Simandi, Ferenc Nagy, Gabor Besenyei, Gyorgy Paszthy, Gyula Pazmandi, Istvan Szita, Gyula Szilagyi, Istvan Toth, Ilona Szigeti nee Kiss
-
Patent number: 4608389Abstract: A compound of the formula: ##STR1## wherein R.sub.1 is a hydrogen atom or a methyl group, R.sub.2 is a lower alkyl group and X is an oxygen atom or a sulfur atom, which is useful as an insecticide.Type: GrantFiled: August 10, 1984Date of Patent: August 26, 1986Assignee: Sumitomo Chemical Company, LimitedInventors: Hirosi Kisida, Makoto Hatakoshi, Sumio Nishida
-
Patent number: 4605519Abstract: The invention relates to novel O- or S-(2-mercaptoalkyl)mono- or dihydrocarbyl carbamothioates and S-(2-mercaptoalkyl)mono- or dihydrocarbyl carbamodithioate. The novel compounds of this invention are useful as collectors in the froth flotation of sulfide mineral ores.Type: GrantFiled: December 9, 1983Date of Patent: August 12, 1986Assignee: The Dow Chemical CompanyInventor: Roger W. Bergman