Benzene Ring Attached Indirectly To The Nitrogen By Nonionic Bonding Patents (Class 558/242)
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Patent number: 8217390Abstract: Polymers that enable the use of high work-function metals as a cathode in optoelectronic devices and optoelectronic devices incorporating the polymers as an electron transport layer.Type: GrantFiled: June 11, 2009Date of Patent: July 10, 2012Assignee: University of WashingtonInventors: Kwan-Yue Jen, Fei Huang, Yuhua Niu, Yong Zhang
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Patent number: 8106141Abstract: Reaction products prepared from reactants including: (a) at least one compound of structural Formula (I): wherein R1 is selected from aryl and heteroaryl; X is selected from a direct bond, —O—, —S—, —NH—, alkylene, cycloalkylene, heterocyclylene, arylene, alkarylene, and heteroarylene; Y is a substituted alkylene group having at least two contiguous carbon atoms and which can be interrupted by one or more —O—, —S—, or —NH— moieties as defined herein, wherein the alkylene group of Y has substituents independently selected from —OH, —NH2, —SH, cycloalkyl, heterocyclyl, aryl, and heteroaryl, or two hydrogen atoms on the same carbon atom of Y are replaced by carbonyl, and wherein at least two substituents of Y are each independently selected from —OH, —NH2, and —SH, as defined herein; and (b) at least one isocyanate functional material.Type: GrantFiled: May 7, 2008Date of Patent: January 31, 2012Assignee: Henkel CorporationInventors: Anthony F. Jacobine, Andrew Messana, David M. Glaser, Steven Thomas Nakos
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Patent number: 8076370Abstract: Provided herein are substituted aromatic compounds, which are tRNA synthetase inhibitors, and hence can be used as antimicrobial agents. Compounds described herein can be used for the treatment or prevention of a condition caused by or contributed to by gram positive, gram negative, anaerobic bacteria or fungal organisms, more particularly against bacterium, for example, Staphylococci, Enterococci, Streptococci, Haemophilus, Moraxalla, Escherichia, Chlamydia, Mycoplasm, Legionella, Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Bacillus or Enterobactericeae, and fungal organisms, for example, Aspergillus, Blastomyces, Candida, Coccidiodes, Cryptococcus, Epidermophyton, Hendersonula, Histoplasma, Microsporum, Paecilomyces, Paracoccidiodes, Pneumocystis, Trichophyton, or Trichosporium. Processes for the preparation of these compounds, pharmaceutical compositions thereof, and methods of treating microbial infections are also provided.Type: GrantFiled: May 3, 2006Date of Patent: December 13, 2011Assignee: Ranbaxy Laboratories LimitedInventors: Biswajit Das, Jasbir Singh Arora, Shahadat Ahmed, Anish Bandyopadhyay, Rita Katoch, Santosh Haribhau Kurhade, Sujata Rathy, Soma Ghosh, Abhijit Datta Khoje, Arti Gujrati, Dilip J. Upadhyay
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Publication number: 20090299074Abstract: The invention provides benzo[b]thiophene derivatives useful as production intermediates for chymase inhibitors, and a process for their production. The invention relates to benzo[b]thiophene derivatives represented by the following formula, and a process for their production.Type: ApplicationFiled: October 27, 2006Publication date: December 3, 2009Applicant: TEIJIN PHARMA LIMITEDInventors: Naoki Yajima, Yaoshinori Sato, Hiroshi Yoshino, Tatsuya Koizumi, Yasuhiro Hiroki
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Patent number: 6140531Abstract: Describes a method of producing N-1-alkenyl carbonylamino compounds represented by the following general formula I, ##STR1## wherein R.sub.1 is the residue of an active hydrogen functional material, n is a number from 1 to a number equal to the number of active hydrogen groups of said active hydrogen functional material, X is selected from O, S and N(R.sub.5), R.sub.5 being hydrogen, hydrocarbyl, or R.sub.5 and R.sub.1 may together form a cyclic ring, R.sub.2, R.sub.3 and R.sub.4 are each independently selected from hydrogen, C.sub.1 -C.sub.4 alkyl and C.sub.2 -C.sub.4 alkenyl.Type: GrantFiled: March 29, 1999Date of Patent: October 31, 2000Assignee: PPG Industries Ohio, Inc.Inventors: Cheruthur Govindan, John M. Pascone
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Patent number: 5952386Abstract: The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.10 alkyl or the like; L is C(.dbd.O)NH or the like; R.sub.2, R.sub.3 and R.sub.4 are independently halogen or the like; R.sub.5, R.sub.6 and R.sub.7 are independently hydrogen or the like; m is an integer of 0 to 4; n is an integer of 0 to 2; X is chlorine or the like; Y is oxygen or the like; and Z is oxygen or the like, which have excellent insecticidal activity so that they are satisfactorily effective for the control of noxious insects.Type: GrantFiled: September 24, 1997Date of Patent: September 14, 1999Assignee: Sumitomo Chemical Company, LimitedInventors: Sanshiro Matsuo, Taro Hirose, Keiichi Izumi, Masaya Suzuki, Noriyasu Sakamoto, Kazunori Tsushima, Shigeru Saito, Hirotaka Takano
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Patent number: 5917015Abstract: A support material for solid phase synthesis is provided having an amine-containing organic group attached to it through a linker.Type: GrantFiled: June 18, 1996Date of Patent: June 29, 1999Assignee: Regents of the University of MinnesotaInventors: Knud J. Jensen, George Barany, Micheal F. Songster, Fernando Albericio, Jordi Alsina, Josef Vagner
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Patent number: 5866512Abstract: Compositions for controlling growth of plant species, and methods for using the compositions, are disclosed. The compositions contain a single-isomer enantiomeric S-benzyl thiocarbamate and are particularly useful in controlling annual weeds associated with rice, soybeans and corn.Type: GrantFiled: December 19, 1997Date of Patent: February 2, 1999Assignee: Celgene CorporationInventors: George W. Matcham, Norman W. Thomas
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Patent number: 5763489Abstract: A compound of the formula ##STR1## wherein R.sup.1 is carboxy or protected carboxy,R.sup.2 is hydrogen, hydroxy or protected hydroxy,R.sup.3 is hydrogen, hydroxy, protected hydroxy, etc.,R.sup.4 is hydrogen or halogen,A.sup.1 is lower alkylene,A.sup.2 is bond or lower alkylene,--R.sup.5 is ##STR2## (in which R.sup.6 is mono(or di or tri)aryl(lower)alkyl and Z is N or CH), etc., and ##STR3## and a pharmaceutically acceptable salt thereof which are useful as medicaments.Type: GrantFiled: October 10, 1996Date of Patent: June 9, 1998Assignee: Fujisawa Pharmaceutical Co., Ltd.Inventors: Kiyoshi Taniguchi, Masanobu Nagano, Kouji Hattori, Kazunori Tsubaki, Osamu Okitsu, Seiichiro Tabuchi
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Patent number: 5750757Abstract: A process for the preparation of an S-alkyl ester of an N-alkyl carbamothioic acid having the formula: ##STR1## wherein R and R.sub.2 are each an alkyl group and R.sub.1 is hydrogen or alkyl, which includes refluxing the corresponding alkyl ester of N-alkyl thiocarbamio acid having the formula I ##STR2## wherein R and R.sub.2 are each alkyl and R.sub.1 is hydrogen or alkyl, in the presence of an acid catalyst selected from the group consisting of iodine and sulfuric acid.Type: GrantFiled: October 29, 1996Date of Patent: May 12, 1998Assignee: Council of Scientific and Industrial ResearchInventors: Abdul Rakeeb Abdul Subhan Deshmukh, Rajan Hiralal Naik, Sagun Kashinath Tandel, Srinivasachari Rajappa
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Patent number: 5565602Abstract: A process which can be used for producing thiolcarbamates is provided wherein the process comprises contacting a reaction mixture with a hydrocarbyl chloride such as, for example, benzyl chloride under a condition which is sufficient to produce a product mixture wherein the reaction mixture comprises carbonyl sulfide, an amine such as, for example, a secondary amine, a solvent; the solvent comprises a tertiary amine; and the reaction mixture, hydrocarbyl halide, and solvent are each present in an amount sufficient to effect the production of a thiolcarbamate. Optionally, the reaction mixture can also comprise a metal hydroxide. Further optionally, the product mixture can be contacted with a metal hydroxide if the reaction mixture does not comprise a metal hydroxide.Type: GrantFiled: March 13, 1995Date of Patent: October 15, 1996Assignee: Phillips Petroleum CompanyInventors: Michael S. Matson, Dean E. Stinn, Michael D. Mitchell
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Patent number: 5196566Abstract: Novel acid-labile tris(alkoxy)benzyl ester handles for use in linking protected amino acid or peptides to a support during peptide synthesis are disclosed. Methods for producing the handles, for linking them to solid support resins and for using the resin-linked handles in peptide synthesis are disclosed.Type: GrantFiled: August 31, 1990Date of Patent: March 23, 1993Assignee: Regents of the University of MinnesotaInventors: George Barany, Fernando Albericio
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Patent number: 5151540Abstract: A method is provided for preparing N-acylaminothiophenols, e.g., N-acetyl-para-aminothiophenol, or aminothiophenols, e.g., para-aminothiophenol, or N,S-diacylaminothiophenols, e.g., N,S-diacetyl-para-aminothiophenol, by reacting any of certain sulfur-containing ketones, viz., an S-(acylaryl) N,N-di(organo)thiocarbamate, e.g., S-(4'-acetophenyl)-N,N-dimethylthiocarbamate, an acylthiophenol acylate ester, e.g., 4-acetothiophenol acetate, or a free acylthiophenol, e.g., 4-acetothiophenol with hydroxylamine or a hydroxylamine salt, to form the oxime of the ketone, subjecting the oxime to a Beckmann rearrangement in the presence of a catalyst to form an S-(N-acyl-aminoaryl) N,N-di(organo)thiocarbamate, e.g., S-(N-acetyl-para-aminophenyl) N,N-dimethylthiocarbamate, an N,S-diacylaminothiophenol, e.g., N,S-diacetyl-paraaminothiophenol, or an N-acyl aminothiophenol, e.g., N-acetyl-para-aminothiophenol, respectively.Type: GrantFiled: November 26, 1986Date of Patent: September 29, 1992Assignee: Hoechst Celanese CorporationInventors: Mohammad Aslam, Kenneth G. Davenport
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Patent number: 4968829Abstract: Substituted phenoxy, phenylthio and anilino compounds, intermediates therefor, synthesis thereof, and their use for the control of pests.Type: GrantFiled: June 19, 1989Date of Patent: November 6, 1990Assignee: Sandoz Ltd.Inventor: Clive A. Henrick
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Patent number: 4801721Abstract: Methods for the alkylation of substituted amines with trifluorate esters is disclosed.Type: GrantFiled: December 19, 1986Date of Patent: January 31, 1989Inventors: James W. Ryan, Alfred Chung
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Patent number: 4697033Abstract: Certain novel derivatives of carbamates and their use for the control of pests.Type: GrantFiled: December 24, 1985Date of Patent: September 29, 1987Assignee: Sandoz Ltd.Inventor: Clive A. Henrick
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Patent number: 4695314Abstract: Novel S-benzyl thiolcarbamates are disclosed, having the formula ##STR1## in which R.sup.1 is selected from the group consisting of hydrogen and methoxy,R.sup.2 is selected from the group consisting of methyl, ethyl, and allyl, andR.sup.3 is selected from the group consisting of straight-chain C.sub.3 -C.sub.6 alkyl optionally substituted with one or two methyl groups, and allyl.The compounds are particularly effective in the control of weeds associated with rice crops.Type: GrantFiled: April 28, 1986Date of Patent: September 22, 1987Assignee: Stauffer Chemical CompanyInventors: Lawrence L. Buren, Donald R. James, Barney J. Randolph, Eugene G. Teach, Harry Tilles, Francis H. Walker
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Patent number: 4617416Abstract: There is disclosed a process for the preparation of thiocarbamates having the following general formula: ##STR1## wherein: R represents alkyl C.sub.1 -C.sub.4 optionally substituted with one or more halogen atoms, alkenyl C.sub.2 -C.sub.4 optionally substituted with one or more halogen atoms, phenyl optionally substituted with one or more halogen atoms, benzyl optionally substituted with one or more halogen atoms on the phenyl ring;R.sup.1 and R.sup.2, equal or different from one another, represent alkyl C.sub.1 -C.sub.4 or cycloalkyl;consisting in reacting organic dithiocarbonates with organic carbamoyl halides, in the presence of an aqueous solution of an inorganic base and a phase transfer catalyst, at a temperature of 10.degree. to 50.degree. C. for time periods of 5 to 10 hours.The thiocarbamates obtained are used as herbicides, fungicides, etc., and in general in various fields of "fine chemicals".Type: GrantFiled: March 19, 1985Date of Patent: October 14, 1986Assignee: Montedison S.p.A.Inventors: Renato Ugo, Stefano Campolmi, Vittorio Carletti