Nitrile Oxides Or Nitrile Imines (i.e., Compounds Having Cyano Bonded Directly To Carbon, Which Carbon May Be Single Bonded To Any Atom But May Be Multiple Bonded Only To Carbon, And Wherein The Nitrogen Of The Cyano Group Is Bonded Directly To Oxygen Or To Nitrogen) Patents (Class 558/299)
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Patent number: 9637618Abstract: A rubber composition for a bead filler contains a diene rubber, a carbon black and a nitrone compound having a carboxy group; the diene rubber contains a natural rubber and a styrene-butadiene rubber, wherein the content of the natural rubber in a total of the diene rubber and the nitrone compound is not less than 60 mass %, and the content of the styrene-butadiene rubber in a total of the diene rubber and the nitrone compound is not greater than 40 mass %; the content of the carbon black is 40 to 80 parts by mass per 100 parts by mass of a total of the diene rubber and the nitrone compound; and the content of the nitrone compound is 0.1 to 10 parts by mass per 100 parts by mass of a total of the diene rubber and the nitrone compound. Such rubber composition exhibits low heat build-up after vulcanization.Type: GrantFiled: December 19, 2014Date of Patent: May 2, 2017Assignee: The Yokohama Rubber Co., Ltd.Inventors: Manabu Kato, Ryota Takahashi, Takahiro Okamatsu, Yoshiaki Kirino
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Publication number: 20140371418Abstract: The invention generally relates to biological engineering of microorganisms and production of chemical compounds therefrom. More particularly, the invention relates to novel genetically engineered microorganisms for the fermentative production of p-aminobenzoic acid and related compounds from fermentable carbon substrates. The biologically derived PABA and related compounds from fermentable carbon substrates can be used in a number of applications including as a food supplement or raw materials for the syntheses of other industrial chemicals or polymers.Type: ApplicationFiled: January 4, 2013Publication date: December 18, 2014Applicant: pAromatics, LLCInventors: Wing On Ng, Shingo Watanabe, Robert W.R. Humphreys, Steven C. Slater
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Patent number: 8853437Abstract: An object of the present invention is to provide a compound having a novel structure for overcoming the defects of conventional steroid agents and NSAIDs. It is found that the particular dihydroxy bodies of eicosapentaenoic acid and docosahexaenoic acid, which have not conventionally been known (11,18-dihydroxy eicosapentaenoic acid (11,18-diHEPE), 17,18-dihydroxy eicosapentaenoic acid (17,18-diHEPE) etc.), have activity of inhibiting neutrophil, thereby solving the object. The present invention unexpectedly remarkably inhibits infiltration into a tissue of, and activation of neutrophil found out at acute inflammation. The compound of the present invention is a compound which has not conventionally been known. Therefore, utility as a new therapeutic is provided.Type: GrantFiled: February 19, 2010Date of Patent: October 7, 2014Assignee: The University of TokyoInventors: Makoto Arita, Hiroyuki Arai, Yousuke Isobe, Ryo Taguchi
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Patent number: 8796175Abstract: The invention relates to the use of at least one compound selected from the class of the sulphoximines for enhancing plants' intrinsic defenses and/or for improving plant growth and/or for enhancing the resistance of plants to plant diseases which are caused by fungi, bacteria, viruses, MLOs (mycoplasma-like organisms) and/or RLOs (rickettsia-like organisms), and/or for enhancing the resistance of plants to abiotic stress factors.Type: GrantFiled: August 17, 2009Date of Patent: August 5, 2014Assignee: Bayer CropScience AGInventors: Peter Jeschke, Wolfgang Thielert, Heike Hungenberg
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Crosslinker, crosslinked polymer material, and production method of the crosslinked polymer material
Patent number: 8530585Abstract: The present invention provides a crosslinker used for crosslinking a polymer material having, in the molecule thereof, a multiple bond reactable with a nitrile oxide, the crosslinker including a bifunctional nitrile oxide having an aromatic nitrile oxide derivative structure in which one hydrogen atom of an aromatic ring is substituted with a nitrile oxide group and all hydrogen atoms at an ortho-position of the nitrile oxide group are substituted with a substituent other than a nitrile oxide group, wherein two such aromatic nitrile oxide derivative structures are bonded to either two oxy groups of a di-oxy structure having the two oxy groups or two carbonyl groups of a di-carbonyl structure having the two carbonyl groups.Type: GrantFiled: February 18, 2011Date of Patent: September 10, 2013Assignees: Toyoda Gosei Co., Ltd., Tokyo Institute of TechnologyInventors: Akishige Seo, Hideyuki Imai, Naoki Iwase, Toshikazu Takata, Yasuhito Koyama, Morio Yonekawa -
CROSSLINKER, CROSSLINKED POLYMER MATERIAL, AND PRODUCTION METHOD OF THE CROSSLINKED POLYMER MATERIAL
Publication number: 20110224380Abstract: The present invention provides a crosslinker used for crosslinking a polymer material having, in the molecule thereof, a multiple bond reactable with a nitrile oxide, the crosslinker including a bifunctional nitrile oxide having an aromatic nitrile oxide derivative structure in which one hydrogen atom of an aromatic ring is substituted with a nitrile oxide group and all hydrogen atoms at an ortho-position of the nitrile oxide group are substituted with a substituent other than a nitrile oxide group, wherein two such aromatic nitrile oxide derivative structures are bonded to either two oxy groups of a di-oxy structure having the two oxy groups or two carbonyl groups of a di-carbonyl structure having the two carbonyl groups.Type: ApplicationFiled: February 18, 2011Publication date: September 15, 2011Applicants: TOYODA GOSEI CO., LTD., TOKYO INSTITUTE OF TECHNOLOGYInventors: Akishige SEO, Hideyuki IMAI, Naoki IWASE, Toshikazu TAKATA, Yasuhito KOYAMA, Morio YONEKAWA -
Publication number: 20100035985Abstract: An ester compound represented by the formula (1): wherein R represents a C1-C4 alkyl group or a C3-C4 alkenyl group, and A represents a single bond or an oxygen atom, has an excellent pest controlling efficacy, and it is useful as an active ingredient of a pest controlling agent.Type: ApplicationFiled: February 27, 2009Publication date: February 11, 2010Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventor: Tatsuya Mori
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Publication number: 20080214387Abstract: Process for modifying catalysts via the deposition of carbon containing residues in the presence of one or more solvents, where the gas phase over the catalyst treatment solution during the treatment is air or an inert gas, and/or the liquid phase contains a templating agent and/or base. The modified catalyst can be used for stereo-, chemo- and regioselective transformations of organic compounds.Type: ApplicationFiled: November 12, 2004Publication date: September 4, 2008Inventors: Daniel Ostgard, Virginie Duprez, Roberta Olindo, Stefan Roder, Monika Berweiler
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Publication number: 20080085458Abstract: The invention pertain to novel photoacid generator compounds of the formula I, II or III wherein R1 is for example C1-C18alkylsulfonyl or phenylsulfonyl, phenyl-C1-C3alkylsulfonyl, naphthylsulfonyl, anthracylsulfonyl or phenanthrylsulfonyl, all optionally substituted, or R1 is a group X1, X2 and X3 independently of each other are O or S; R?1, is e.g. phenylenedisulfonyl, naphthylenedisulfonyl, diphenylenedisulfonyl, or oxydiphenylenedisulfonyl, all optionally substituted; R2 is halogen or C1-C10haloalkyl; X is halogen; Ar1 is for example biphenylyl or fluorenyl, or is substituted naphthyl; Ar?1 is heteroarylene, optionally substituted; R8, R9, R10 and R11 for example are C1-C6alkyl which is unsubstituted or substituted by halogen; or R8, R9 and R10 are phenyl which is unsubstituted or substituted by C1-C4alkyl or halogen; or R10 and R11 together are 1,2-phenylene or C2-C6alkylene which is unsubstituted or substituted by C1-C4alkyl or halogen.Type: ApplicationFiled: July 11, 2005Publication date: April 10, 2008Inventors: Hitoshi Yamato, Toshikage Asakura, Tobias Hintermann
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Patent number: 7285600Abstract: The present invention is directed to nitrile-oxide precursor compounds, and their preparation and use as an irreversible cross-linking agent in polymers having appropriate functionality, i.e., alkenes, alkynes nitriles, and isocyanates. The present invention is also directed to the use of nitrile oxide compound in filled or unfilled applications such as pressure sensitive adhesives, reactive hot melts, polyurethane dispersions, thermosetting adhesives, thermoplastic adhesives or coatings.Type: GrantFiled: December 21, 2001Date of Patent: October 23, 2007Assignee: National Starch and Chemical Investment Holding CorporationInventors: Brian S. Huffman, Rose Ann Schultz, Peter J. Schlom, James W. Nowicki, Ju-Ming Hung
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Patent number: 6355826Abstract: This invention discloses a process for the synthesis of stable aryl nitrile oxides which comprises the sequential steps of (1) halomethylating a halomethyl group onto a substituted aromatic compounds wherein said halomethyl group is halomethylated onto a position that is ortho to at least one of the substituent groups on the substituted aromatic compound; (2) converting the ortho halomethylated-substituted aromatic compound into an ortho-substituted aromatic aldehyde by reacting the ortho halomethylated-substituted aromatic compound with a salt selected from the group consisting of sodium 2-nitropropane and potassium 2-nitropropane in a lower alcohol solvent; (3) converting the ortho-substituted aromatic aldehyde into an ortho-substituted aromatic; and (4) converting the ortho-substituted aromatic oxime into the ortho-substituted aryl nitrile oxide by reacting the ortho-substituted aromatic oxime with an aqueous sodium hypochlorite solution.Type: GrantFiled: June 26, 2000Date of Patent: March 12, 2002Assignee: The Goodyear Tire & Rubber CompanyInventor: Dane Kenton Parker
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Patent number: 6007583Abstract: Use of compounds of the formula ##STR1## where the radicals R.sup.1, R.sup.2 and A are as defined in the description, as bleach activators in bleaching detergents and cleaners.Type: GrantFiled: October 19, 1998Date of Patent: December 28, 1999Assignee: Clariant GmbHInventor: Bernd Nestler
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Patent number: 5710290Abstract: A suitably functionalized cycloaliphatic nitrile oxide can be used to convert unsaturated sites to alcohol or epoxy sites. The cycloaliphatic nitrile oxide may be useful in applications such as the preparation of polycarbonates, polyurethanes, or crosslinked polybutadiene, or poly(styrene-butadiene). The cycloaliphatic nitrile oxide is represented by the formula: ##STR1## wherein R' and each R are independently hydrogen, C.sub.1 -C.sub.12 alkyl, or halo; X and X' are independently hydrogen, halo, hydroxyl, or together with the carbon atoms to which they are attached form an epoxy group, with the proviso that at least one of X and X' is not hydrogen; and n is 1 or 2.Type: GrantFiled: October 21, 1996Date of Patent: January 20, 1998Assignee: The Dow Chemical CompanyInventors: Zenon Lysenko, Clark H. Cummins, Ramki Subramanian, Richard F. Fibiger
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Patent number: 5527944Abstract: A compound of the formula ##STR1## where R.sup.1 and R.sup.2, independently of one another, are each C.sub.1 -C.sub.10 -alkyl, C.sub.1 -C.sub.10 -alkoxy, C.sub.5 -C.sub.10 --cycloalkyl or C.sub.5 -C.sub.10 -aryl, each of which may furthermore contain from 1 to 3 non-adjacent nitrogen, oxygen or sulfur atoms as hetero atoms in the carbon chain or carbon ring and may be substituted by 1 to 3 C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy groups, R.sup.1 or R.sup.2 may be hydrogen or R.sup.1 and R.sup.2 together form a bridge of 2 to 14 carbon atoms, where some of the carbon atoms may furthermore be part of an aromatic ring system, A is an n-valent organic radical and n is an integer equal to or greater than 2.Type: GrantFiled: September 19, 1995Date of Patent: June 18, 1996Assignee: BASF AktiengesellschaftInventors: Gerhard Bauer, Oral Aydin, Beate Strecker, Alfred Oftring
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Patent number: 5358955Abstract: The present invention relates to a compound of the formula ##STR1## or a pharmaceutically acceptable salt thereof wherein W is selected from optionally substituted pyridyl, naphthyl, and quinolyl; which inhibits lipoxygenase enzyme activity and leukotriene biosynthesis and is useful in the treatment of inflammatory disease states; also disclosed are leukotriene biosynthesis inhibiting compositions and a method for inhibiting lipoxygenase enzyme activity and leukotriene biosynthesis.Type: GrantFiled: June 2, 1993Date of Patent: October 25, 1994Assignee: Abbott LaboratoriesInventors: Dee W. Brooks, Teodozy J. Kolasa
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Patent number: 5284853Abstract: The invention provides novel 2, 3, 6 substituted quinazolinones of the formula ##STR1## wherein, R, R.sup.6 and X are defined in the specification which have activity as angiotensin II (AII) antagonists.Type: GrantFiled: April 23, 1993Date of Patent: February 8, 1994Assignee: American Cyanamid CompanyInventors: Jeremy I. Levin, Aranapakam M. Venkatesan
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Patent number: 5179223Abstract: A process for producing a carbamate is disclosed. In one embodiment, the process comprises contacting a mixture comprising a primary amine component, an urea component and a hydroxy nitrogen component, in particular at least one oxime, at conditions effective to form a carbamate. Certain novel carbamates are also disclosed.Type: GrantFiled: December 13, 1990Date of Patent: January 12, 1993Assignee: Union Carbide Chemicals & Plastics Technology CorporationInventors: Tak W. Leung, Donald C. Best, Bernard D. Dombek
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Patent number: 5153358Abstract: A novel process for the preparation of .alpha.-alkylated .alpha.-amino acids and .alpha.-halogenated .alpha.-amino acids is disclosed. These .alpha.-alkylated .alpha.-amino acids and .alpha.-halogenated .alpha.-amino acids are useful as intermediates for the preparation of enzyme inhibitors (for example, renin inhibitors) and other peptides or amino acid derivatives or analogs.Type: GrantFiled: January 30, 1991Date of Patent: October 6, 1992Assignee: Abbott LaboratoriesInventor: Thomas M. Zydowsky