Abstract: N, N'-dibenzylethylenediamine-diacetylsalicylate for effecting an analgesic, antipyretic, spasmolytic or anti-inflammatory response in a mammalian host.

Abstract: 2-OR-4-trifluoromethylbenzoic acid wherein R is H or acyl.The compounds are useful in the treatment of pathological cardiovascular conditions, particularly in the prophylaxis of the thromboembolic diseases.The compounds are made by reacting m-trifluoromethyl phenol with potassium carbonate and carbon dioxide at an elevated temperature and pressure and, if desired, acetylating the 2-OH compound thus obtained or reacting it with a phosphonating agent.The invention also embraces pharmaceutical compositions in which the compounds constitute the effective agent and a method of treatment.

Abstract: Process for the manufacture of a heterocyclic compound of the formula I ##STR1## in which Y denotes a --CN, --COOR' or ##STR2## group, in which R' can be an optionally substituted alkyl or aryl radical and R" and R"' independently of one another can have the same meaning as R' or can be hydrogen or, conjointly with the nitrogen atom, can form a heterocyclic 5-membered or 6-membered ring and X denotes a --S-- or --O-- atom or a --NR"-- group and the ring A can carry non-ionic substituents or optionally substituted fused rings, wherein a nitrile of the formula IInc -- ch.sub.2 -- y (ii)is reacted, in organic solvents, with a lower alcohol of the formula IIIr -- oh (iii)using a molar ratio of nitrile to alcohol of 1:0.9 to 1:1.2, in the presence of an anhydrous strong acid at temperatures of -10.degree. to +40.degree.