Halogen Attached Indirectly To The Sulfonate Group By Acyclic Nonionic Bonding Patents (Class 562/113)
  • Compositions useful for fluorine magnetic resonance imaging
    Patent number: 4913853
    Abstract: Water soluble, substantially nontoxic salts of compounds of the formula:CF.sub.3 Rwherein R is --SO.sub.3 H, --SO.sub.2 NH.sub.2 or --PO.sub.3 H.sub.2, are useful for obtaining fluorine magnetic resonance images of body organs and tissues. Illustrative salts of such compounds include sodium trifluoromethane sulfonate, N-methylglucaminium trifluoromethanesulfonate and N-methylglucaminium trifluoromethanesulfonamide.
    Type: Grant
    Filed: December 10, 1986
    Date of Patent: April 3, 1990
    Assignee: Mallinckrodt, Inc.
    Inventor: George B. Hoey
  • Process for the preparation of perhaloalkanesulfinic and -sulfonic acids, perhaloalkanesulfinic and -sulfonic acid salts and other derivatives of these acids
    Patent number: 4866190
    Abstract: A process for the preparation of perhaloalkanesulfinic and -sulfonic acids and derivatives of these acids. A perhaloalkanesulfinic acid salt is prepared by contacting a metal hydroxymethanesulfinate (preferably, a sodium, zinc or copper hydroxymethanesulfinate) with a perhaloalkyl halide group, in a polar solvent. Optionally, the perhaloalkanesulfinic acid salt is then converted to a perhaloalkanesulfinic or -sulfonic acid or a derivative of either of these acids.
    Type: Grant
    Filed: February 3, 1988
    Date of Patent: September 12, 1989
    Assignee: Rhone-Poulenc Chimie
    Inventors: Marc Tordeux, Bernard Langlois, Claude Wakselman