Halogen Patents (Class 562/456)
  • Patent number: 4160842
    Abstract: New insecticidal (.beta.-phenylvinyl)cyclopropanecarboxylates having on the phenyl ring one or more substituents such as halogen, cyano, nitro, lower alkyl, aryl, aralkyl, lower alkoxy, lower alkylthio, aryloxy, arylthio, lower haloalkyl, di(lower alkyl)amino, or methylenedioxy are described, and their preparation and insecticidal utility are exemplified.
    Type: Grant
    Filed: August 27, 1976
    Date of Patent: July 10, 1979
    Assignee: FMC Corporation
    Inventor: John F. Engel
  • Patent number: 4160015
    Abstract: 5-Gluconamido-2,4,6-triiodo-N-methylisophthalamic acid, 3-acetamido-2,4,6-triiodo-5-trishydroxymethylacetamido-benzoic acid, related compounds and salts and esters thereof are useful as x-ray contrast agents. The corresponding acyl halides are useful as intermediates.
    Type: Grant
    Filed: August 28, 1978
    Date of Patent: July 3, 1979
    Assignee: Mallinckrodt, Inc.
    Inventor: Philip E. Wiegert
  • Patent number: 4159278
    Abstract: Compounds represented below ##STR1## and pharmaceutical compositions thereof, the compositions including the non-substituted phenylene dioxamates are useful in the prophylactic treatment of sensitized mammals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature.
    Type: Grant
    Filed: October 31, 1977
    Date of Patent: June 26, 1979
    Assignee: The Upjohn Company
    Inventors: Charles M. Hall, John B. Wright
  • Patent number: 4157447
    Abstract: Intermediates for insecticidal (.beta.-phenyl-.beta.-substituted-vinyl)cyclopropanecarboxylates in which the .beta.-substituent may be halogen, lower alkyl, lower haloalkyl, cyano, carbomethoxy, or carbethoxy are described and exemplified.
    Type: Grant
    Filed: February 21, 1978
    Date of Patent: June 5, 1979
    Assignee: FMC Corporation
    Inventor: John F. Engel
  • Patent number: 4156726
    Abstract: There are described compounds of formula I, ##STR1## in which R.sub.5 to R.sub.8 may be a variety of substituents, OR AN ADJACENT PAIR OF R.sub.5, R.sub.6, R.sub.7 and R.sub.8 form a chain --COCH.dbd.C(COOH)NRh--,Or one of R.sub.5, R.sub.6, R.sub.7 and R.sub.8 form a group of formula II, ##STR2## in which Ra, Rb and Rc have the same significances as R.sub.5, R.sub.6, R.sub.7 and R.sub.8,X is an optionally interrupted or substituted hydrocarbon chain,Rg and Rh, which may be the same or different are each alkyl, alkenyl, phenyl-alkyl, alkanoyl, benzoyl or phenylalkanoyl,Or Rg and R.sub.8 and/or Rh and Rc in formula II, together form a chain --(CH.sub.2).sub.n --, and n is 2, 3 or 4.There are also described processes for making the compounds and pharmaceutical, e.g. anti-allergic, compositions containing the compounds.
    Type: Grant
    Filed: November 26, 1975
    Date of Patent: May 29, 1979
    Assignee: Fisons Limited
    Inventors: Roger C. Brown, Hugh Cairns, Anthony R. Payne
  • Patent number: 4154961
    Abstract: Anti-allergic agents of aromatic oxamic acid derivation present the following formula: ##STR1## in which A is a member selected from the group consisting of .alpha.-naphthyl, .beta.-naphthyl, phenyl, 2,6-di-chlorophenyl, and substituted phenyl moieties containing from one to three substituents in any of the 2,3,4 and 5 positions of the phenyl ring, independently selected from the group consisting of lower alkyl, lower alkylthio, lower alkylsulfinyl, lower alkoxy, hydroxy (lower)alkoxy, 2-(oxalyloxy) ethoxy, benzyloxy, N-mono- and di-lower alkylamino(lower)alkoxy, halo, sulfamyl, polyhalo(lower)alkyl, carbamyl, N-lower alkylcarbamyl, nitro, mono and di lower alkylamino, carboxy, lower alkylcarbonyl, carb(lower)alkoxy, phenoxy(lower)alkoxy, and oxalamidophenoxy radicals;And pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 19, 1977
    Date of Patent: May 15, 1979
    Assignee: American Home Products Corporation
    Inventors: John H. Sellstedt, Charles J. Guinosso, Albert J. Begany
  • Patent number: 4148916
    Abstract: The invention provides oxaminic acids and esters thereof, useful for the treatment of allergic conditions, a process for the preparation of said compounds and pharmaceutical compositions containing these compounds.
    Type: Grant
    Filed: June 22, 1978
    Date of Patent: April 10, 1979
    Assignee: Sandoz Ltd.
    Inventor: Trevor G. Payne
  • Patent number: 4125625
    Abstract: Tropone derivatives characterized by having a derivative of oxamic acid at positions 2 and or 5 are disclosed. In addition, the tropone nucleus can be optionally further substituted. The foregoing compounds are useful for preventing or treating allergic conditions in a mammal. Methods for the preparation and use of said compounds are disclosed.
    Type: Grant
    Filed: May 31, 1977
    Date of Patent: November 14, 1978
    Assignee: Ayerst, McKenna & Harrison Limited
    Inventors: Jehan F. Bagli, Tibor Bogri
  • Patent number: 4119783
    Abstract: Pharmaceutical compositions having as the active agent a compound of the formula ##STR1## useful for preventing allergic manifestations in sensitized mammals and novel compounds.
    Type: Grant
    Filed: February 18, 1977
    Date of Patent: October 10, 1978
    Assignee: The Upjohn Company
    Inventors: Charles M. Hall, John B. Wright