Two Carboxamido Carbonyls Having No Carboxamido Nitrogen Between The Carbonyls Patents (Class 564/160)
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Patent number: 10844305Abstract: The invention provides for a process for preparing a lubricating grease. The process can be carried out in the presence of a base oil and avoids the use of diisocyanate reagents.Type: GrantFiled: July 22, 2016Date of Patent: November 24, 2020Assignee: Shell Oil CompanyInventors: Thomas Jakob Visser, Adam Petrus Van Zwieten, Matthias Eggenstein
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Patent number: 8987524Abstract: A process for the manufacture of Sevoflurane CF3—CH(OCH2F)—CF3 which comprises (a) manufacturing a substituted malonic acid derivative of formula (I): R1OOC—CH(OCH2X)—COOR2 or of formula (II): R3HNOC—CH(OCH2X)—CONHR4, wherein X is OH or a leaving group which can be substituted by nucleophilic substitution and wherein R1, R2 R3, R4, equal to or different from each other, are independently selected from the group consisting of H, an alkyl group having from 1 to 10 carbon atoms which is optionally substituted by at least one halogen atom, an aralkyl group, and an aryl group; and (b) further reacting said malonic acid derivative as intermediate for the manufacture of Sevoflurane CF3—CH(OCH2F)—CF3.Type: GrantFiled: August 10, 2010Date of Patent: March 24, 2015Assignee: Solvay Fluor GmbHInventor: Max Josef Braun
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Patent number: 8975441Abstract: The present invention generally relates to a process for preparing 2,2-dibromomalonamide from 2,2-dibromo-3-cyanoacetamide.Type: GrantFiled: November 18, 2010Date of Patent: March 10, 2015Assignee: Dow Global Technologies LLCInventors: Charles D. Gartner, Dawn Carsten
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Publication number: 20140346089Abstract: The invention relates to a class of novel surfactants that have utility in the recovery and/or extraction of oil.Type: ApplicationFiled: April 22, 2014Publication date: November 27, 2014Inventors: David S. Soane, Rosa Casado Portilla, John H. Dise, Robert P. Mahoney
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Publication number: 20140309174Abstract: The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R7, X1, X2, R, Q, and n are as defined herein.Type: ApplicationFiled: November 12, 2013Publication date: October 16, 2014Applicant: Eisai Co., LtdInventors: James J. Kowalczyk, Galina Kuznetsov, Shawn Schiller, Boris M. Seletsky, Mark Spyvee, Hu Yang
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Patent number: 8841484Abstract: Disclosed are certain partially fluorinated amide compounds and composite materials containing the compounds. Also disclosed are methods for making the composite materials.Type: GrantFiled: September 20, 2011Date of Patent: September 23, 2014Assignee: E I du Pont de Nemours and CompanyInventors: Keith W. Hutchenson, Anilkumar Raghavanpillai, Stefan Reinartz
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Patent number: 8835502Abstract: The invention provides methods of treating Friedreich's ataxia using histone deacetylase inhibitors.Type: GrantFiled: April 15, 2013Date of Patent: September 16, 2014Assignee: The Scripps Research InstituteInventors: Joel M. Gottesfeld, Kai Jenssen, David M. Herman, Ryan Burnett, C. James Chou
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Patent number: 8785691Abstract: The novel lipophilic metal extractants of the class dialkyldiaza-tetraalkyloctanediamide (DADA) useful to selectively separate trivalent americium (sup. 241 Am) from trivalent lanthanides are represented by the formula 1: Wherein R is a C1 to C5 normal alkyl and R? is a C4 to C8 normal and branched alkyl group. The compounds are synthesized at high yield and purity by the reaction of corresponding N,N?-dialkylethylenediamine and N,N-dialkyl-2-chloroacetamide. The separation is achieved by utilizing the soft-soft interaction between the trivalent actinides and ‘N’ atoms of the extractant. Both soft donor “n” and hard donor ‘O’ sites are incorporated in the molecule for better extraction of trivalent actinides over trivalent lanthanides. Thus, this molecule can be used as selective extractant to separate trivalent actinides from trivalent lanthanides.Type: GrantFiled: September 11, 2009Date of Patent: July 22, 2014Assignee: Secretary, Department of Atomic EnergyInventors: Joti Nath Sharma, Ritesh Ruhela, Smitha Manohar, Piaray Kishen Wattal, Ashok Kumar Suri
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Publication number: 20140127429Abstract: A method of forming a coloured substrate, comprising applying to or incorporating within the substrate a diacetylene compound, and exposing the substrate to (i) a first, activating stimulus that converts the diacetylene compound from an unreactive to a reactive form, and (ii) a second stimulus that causes the reactive form of the diacetylene compound to polymerize and form the coloured substrate, wherein the diacetylene compound reverts to its unreactive form on removal of the activating stimulus and is of formula I: Y—C?C—C?C—(CH2)n-T-Q-Z (I) wherein: n=an odd integer; T=CO, CS or a bond; Q=NH, S, O, OCONH, NHCONH, NH—CHE-CONH, NHCOO or NHCSNH wherein E is H or a C1-20 alkyl group; Z=H or a hydrocarbon group containing 1 to 20 carbon atoms; Y=H or any group comprising at least one carbon atom.Type: ApplicationFiled: February 24, 2012Publication date: May 8, 2014Applicant: DATALASE LTD.Inventors: Anthony N. Jarvis, Christopher A. Wyres, Benjamin Mulchin, Adam O'Rourke
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Publication number: 20140081045Abstract: Disclosed are metal plating compositions and methods. The metal plating compositions provide good leveling performance and throwing power.Type: ApplicationFiled: September 16, 2012Publication date: March 20, 2014Applicant: Rohm and Haas Electronic Materials LLCInventors: Erik Reddington, Gonzalo Urrutia Desmaison, Zukra I. Niazimbetova, Donald E. Cleary, Mark Lefebvre
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Patent number: 8664405Abstract: The object is to provide a stable SM-108 derivative, which is effective as a carcinostatic agent, particularly an SM-108 derivative having good storage stability. An SM-108 compound having good storage stability can be produced by producing an organic sulfonic acid salt compound of SM-108. Further, a crystalline SM-108 compound containing a trace amount of an organic carboxylic acid can be produced by using an aqueous solution of the organic sulfonic acid salt of SM-108, and by adding an alkali metal salt of an organic carboxylic acid to the aqueous solution to neutralize the aqueous solution and then causing the crystal precipitation in the solution.Type: GrantFiled: September 16, 2008Date of Patent: March 4, 2014Assignee: Fujifilm CorporationInventors: Nobuo Kato, Yusuke Higuchi, Chihiro Kondo, Makoto Sunagawa
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Publication number: 20140057816Abstract: The invention relates to a class of novel surfactants that have utility in the recovery and/or extraction of oil.Type: ApplicationFiled: November 5, 2012Publication date: February 27, 2014Applicant: Soane Energy, LLCInventors: David S. Soane, Rosa Casado Portilla, John H. Dise, Robert P. Mahoney
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Publication number: 20130333840Abstract: This invention relates to a polyether-amido-amine corn-pound, obtainable by a two-step reaction of a poly-etheramine with an alkyl acrylate and a polyalkyle-neimine, whereas the polyetheramine and the polyalkyleneimine have at least one primary or secondary amine group, in which the first step comprises the reaction of the polyetheramine with the alkyl acrylate and the second step comprises the reaction of the polyalkyleneimine with the product of the first step. The invention also relates to a method for synthesising a polyether-amido-amine compound by a two-step-reaction. Another object of this invention is a curable composition containing at least one polyether-amido-amine-compound of this invention and a method for coating the surface of a substrate or for binding at least two substrates together using such a curable composition.Type: ApplicationFiled: February 3, 2012Publication date: December 19, 2013Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Frans A. Audenaert, Martin A. Hutchinson, Ian Robinson
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Publication number: 20130306098Abstract: The present invention relates to bleaching composition for keratin fibres, especially human hair, comprising at least one compound with bleaching and/or highlighting effect and a lipidic compound.Type: ApplicationFiled: December 23, 2011Publication date: November 21, 2013Applicant: KAO GERMANY GMBHInventors: Jonathan Wood, Mustafa Grit
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Patent number: 8580712Abstract: Novel bis(dialkylamide) compounds having the formula: R2R3NOC—R1a—CONR4R5 are particularly useful solvents, for example in plant-protection formulations.Type: GrantFiled: December 19, 2007Date of Patent: November 12, 2013Assignee: Rhodia OperationsInventors: Jean-Manuel Mas, Valerio Bramati, Massimo Guglieri, Wagner Celio Ferraz Lourenco
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Publication number: 20130225409Abstract: Quaternary ammonium, betaine, or sulfobetaine compositions derived from fatty amines, wherein the fatty amine is made by reducing the amide reaction product of a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives and a secondary amine, are disclosed. Quaternary ammonium, betaine, or sulfobetaine compositions derived from fatty amidoamines, wherein the amidoamine is made by reacting of a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives and an aminoalkyl-substituted tertiary amine, are also disclosed. The quaternized compositions are advantageously sulfonated or sulfated. In one aspect, the ester derivative of the C10-C17 monoun-saturated acid or octadecene-1,18-dioic acid is a lower alkyl ester. In other aspects, the ester derivative is a modified triglyceride made by self-metathesis of a natural oil or an unsaturated triglyceride made by cross-metathesis of a natural oil with an olefin.Type: ApplicationFiled: October 25, 2011Publication date: August 29, 2013Applicant: Stepan CompanyInventors: Dave R. Allen, Marcos Alonso, Randal J. Bernhardt, Aaron Brown, Sangeeta Ganguly-Mink, Andrew D. Malec, Teresa Manuel, Ronald A. Masters, Lawrence A. Munie, Dennis S. Murphy, Patti Skelton, Brian Sook, Michael R. Terry, Jeremy Aaron Weitgenant, Laura Lee Whitlock, Michael Wiester, Patrick Shane Wolfe
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Patent number: 8273398Abstract: The present invention concerns geranylamine derivates of oxalic acid, use of the same as flavorings and certain mixtures, compositions, preparations and semi-finished goods containing one or more such compounds.Type: GrantFiled: September 23, 2009Date of Patent: September 25, 2012Assignee: Symrise AGInventors: Michael Backes, Jan Looft
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Publication number: 20120172626Abstract: The novel lipophilic metal extractants of the class dialkyldiaza-tetraalkyloctanediamide (DADA) useful to selectively separate trivalent americium (sup. 241 Am) from trivalent lanthanides are represented by the formula 1: Wherein R is a C1 to C5 normal alkyl and R? is a C4 to C8 normal and branched alkyl group. The compounds are synthesized at high yield and purity by the reaction of corresponding N,N?-dialkylethylenediamine and N,N-dialkyl-2-chloroacetamide. The separation is achieved by utilizing the soft-soft interaction between the trivalent actinides and ‘N’ atoms of the extractant. Both soft donor “n” and hard donor ‘O’ sites are incorporated in the molecule for better extraction of trivalent actinides over trivalent lanthanides. Thus, this molecule can be used as selective extractant to separate trivalent actinides from trivalent lanthanides.Type: ApplicationFiled: September 11, 2009Publication date: July 5, 2012Applicant: Secretary ,Department of Atomic EnergyInventors: Joti Nath Sharma, Ritesh Ruhela, Smitha Manohar, Piaray Kishen Wattal, Ashok Kumar Suri
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Publication number: 20120157708Abstract: A process for the manufacture of Sevoflurane CF3—CH(OCH2F)—CF3 which comprises (a) manufacturing a substituted malonic acid derivative of formula (I): R1OOC—CH(OCH2X)—COOR2 or of formula (II): R3HNOC—CH(OCH2X)—CONHR4, wherein X is OH or a leaving group which can be substituted by nucleophilic substitution and wherein R1, R2 R3, R4, equal to or different from each other, are independently selected from the group consisting of H, an alkyl group having from 1 to 10 carbon atoms which is optionally substituted by at least one halogen atom, an aralkyl group, and an aryl group; and (b) further reacting said malonic acid derivative as intermediate for the manufacture of Sevoflurane CF3—CH(OCH2F)—CF3.Type: ApplicationFiled: August 10, 2010Publication date: June 21, 2012Applicant: SOLVAY FLUOR GMBHInventor: Max Josef Braun
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Publication number: 20120136073Abstract: There are provided for herein novel amine-containing transfection compounds and methods for making and using same. The compounds are generally obtained by reacting a primary amine with an unsaturated compound. Transfection complexes made using the amine-containing transfection compounds in combination with additional compounds to encapsulate biologically active agents such as nucleic acids are also provided for herein. Methods of using the transfection complexes for the in vivo or in vitro delivery of biologically active agents are also described. The transfection complexes of the present invention are highly potent, thereby allowing effective modulation of a biological activity at relatively low doses compared to analogous transfection compounds known in the art.Type: ApplicationFiled: November 15, 2011Publication date: May 31, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Zhiwei Yang, Parul Angrish, Xavier de Mollerat du Jeu, Kristin Wiederholt
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Publication number: 20120083533Abstract: A therapy for renal diseases, in particular renal diseases which develop in diabetic patients or patients who have been subjected to a treatment with an antitumor chemotherapy such as a platinum derivative and more generally cytotoxic drugs at renal level for treating of neoplastic diseases. More particularly, the present invention relates to palmitoylethanolamide and diethanolamide of fumaric acid for use in the treatment of renal diseases, in particular those caused by dysmetabolic diseases or by toxic or chemotherapy agents, such as platinum derivatives. Palmitoylethanolamide is used preferably in micronized or ultra-micronized form. Diethanolamide of fumaric acid is used preferably in aqueous solution.Type: ApplicationFiled: October 3, 2011Publication date: April 5, 2012Inventors: Francesco Della Valle, Raffacle Migliaccio, Maria Federica Della Valle
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Publication number: 20120021044Abstract: The present invention provides a novel cationic lipid, a preparation method of the same and a delivery system comprising the same. The cationic lipid of the present invention is used for the preparation of delivery systems of nucleic acids or physiologically active anionic proteins. The cationic lipid of the present invention can be conveniently prepared and purified by a simple process and is therefore economically highly advantageous for industrial-scale production thereof. Further, a nucleic acid or protein delivery system comprising the cationic lipid of the present invention not only significantly improves the intracellular delivery efficiency of desired nucleic acid drugs (such as DNAs, RNAs, siRNAs, antisense oligonucleotides, and nucleic acid aptamers) or anionic proteins having physiological activity, but also is usefully used to augment therapeutic efficacy of nucleic acid or protein drugs due to attenuated cytotoxicity of the delivery system.Type: ApplicationFiled: August 20, 2008Publication date: January 26, 2012Applicants: SNU R&DB FOUNDATION, KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATIONInventors: Yu-Kyoung Oh, Min-Sung Suh, Hye-Jeong Shin, Ga Yong Shim
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Publication number: 20110319516Abstract: Release agents with increased affinity toward nano-imprint lithography template surfaces interact strongly with the template during separation of the template from the solidified resist in a nano-imprint lithography process. The strong interaction between the surfactant and the template surface reduces the amount of surfactant pulled off the template surface during separation of a patterned layer from the template in an imprint lithography cycle. Maintaining more surfactant associated with the surface of the template after the separation of the patterned layer from the template may reduce the amount of surfactant needed in a liquid resist to achieve suitable release of the solidified resist from the template during an imprint lithography process. Strong association of the release agent with the surface of the template facilitates the formation of ultra-thin residual layers and dense fine features in nano-imprint lithography.Type: ApplicationFiled: September 7, 2011Publication date: December 29, 2011Applicant: MOLECULAR IMPRINTS, INC.Inventors: Frank Y. Xu, Weijun Liu
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Publication number: 20110318479Abstract: Disclosed are metal plating compositions and methods. The metal plating compositions provide good leveling performance and throwing power.Type: ApplicationFiled: September 6, 2011Publication date: December 29, 2011Applicant: Rohm and Haas Electronic Materials LLCInventors: Erik REDDINGTON, Gonzalo Urrutia DESMAISON, Zukhra I. NIAZIMBETOVA, Donald E. CLEARY, Mark LEFEBVRE
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Publication number: 20110269652Abstract: The invention relates to gemini surfactants of formula IA wherein A is a core derived from an organic polyhydroxy compound; R1 and R2 are each independently a hydrophobic group; and R3 and R4 are each independently a surfactant head group. Such surfactants can be used as components of fluids used in the petroleum industry or used in formulating cleansing compositions or detergent compositions.Type: ApplicationFiled: October 29, 2009Publication date: November 3, 2011Applicant: ST. FRANCIS XAVIER UNIVERSITYInventors: D. Gerrard Marangoni, T. Bruce Grindley, Nusrat Jahan, Christian Petropolis, Thomas Tran, Nawal Paul
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Patent number: 8017804Abstract: The present invention is related to a compound according to formula (I), wherein R1 and R2 are each and independently selected from the group comprising alkyl; n is any integer between 1 and 4; R3 is an acyl selected from the group comprising lysyl, ornithyl, 2,4-diaminobutyryl, histidyl and an acyl moiety according to formula (II), wherein m is any integer from 1 to 3 and YÉ is a pharmaceutically acceptable anion.Type: GrantFiled: May 6, 2005Date of Patent: September 13, 2011Assignee: Silence Therapeutics AGInventors: Oliver Keil, Jörg Kaufmann
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Patent number: 7919528Abstract: Novel PDF inhibitors and novel methods for their use are provided.Type: GrantFiled: May 30, 2003Date of Patent: April 5, 2011Assignee: GlaxoSmithKline LLCInventors: Kelly M. Aubart, Andrew B. Benowitz, Siegfried B. Christensen, IV, Joseph M. Karpinski, Jinhwa Lee, Domingos J. Silva
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Publication number: 20110070657Abstract: The present inventions include methods and compositions for detecting the presence of ions and measuring the level or concentration of ions in a sample by nuclear magnetic resonance (NMR) using magnetic particles. In particular, the inventions include the preparation and use of magnetic particles having synthetic ion chelators covalently bound to their surfaces. In the presence of target ions, the surface-modified magnetic particles form clusters, which can be monitored by NMR relaxation measurements. The relaxation times can then be used to detect specific ions and determine their concentration. The described methods, compositions, and devices are useful for a variety of applications including biomedical applications in diagnostics and imaging.Type: ApplicationFiled: August 18, 2008Publication date: March 24, 2011Applicant: THE GENERAL HOSPITAL CORPORATIONInventors: Lee Josephson, Sonia Taktak
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Publication number: 20110039937Abstract: The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient, vorinostat. In particular it relates to an efficient process for the preparation of vorinostat of high purity without the requirement to isolate any synthetic intermediate compounds.Type: ApplicationFiled: February 6, 2009Publication date: February 17, 2011Inventors: Abhay Gaitonde, Bharati Choudhari
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Publication number: 20110009641Abstract: Nitrogen-containing lipids prepared from the conjugate addition of amines to acrylates, acrylamides, or other carbon-carbon double bonds conjugated to electron-withdrawing groups are described. Methods of preparing these lipids from commercially available starting materials are also provided. These amine-containing lipids or salts forms of these lipids are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these lipids, they are particularly suited for the delivery of polynucleotides. Complexes or nanoparticles containing the inventive lipid and polynucleotide have been prepared. The inventive lipids may also be used to in preparing microparticle for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.Type: ApplicationFiled: June 14, 2006Publication date: January 13, 2011Inventors: Daniel G. Anderson, Andreas Zumbuehl, Elizaveta Sergeyevna Leshchiner (Turkhanova), Robert S. Langer, Michael Goldberg
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Publication number: 20100280186Abstract: Aromatic polyamines are derivatized with polycarboxylic acids or their derivatives to form polyamine amides) containing pendant amine groups; the derivatives have enhanced curative properties when used as curatives for polyureas, hybrid epoxy-urethanes, hybrid urea-urethanes, chain extenders for polyurethane and polyurea elastomers, and also for reaction injection molding (RIM) products.Type: ApplicationFiled: August 28, 2009Publication date: November 4, 2010Inventors: Herman P. Benecke, Alex W. Kawczak, Daniel B. Garbark
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Publication number: 20100234640Abstract: This invention provides a comprehensive solution which comprises the production of a bed of ash-containing hot char via the pyrolysis of coal which generates a hydrogen rich gas that, subsequent to its cleanup, can be synthesized into chemicals and/or transportation fuels, while the hot char is used to: (i) reduce SO2 and NOX to elemental sulfur and to elemental nitrogen, respectively; (ii) react hot char with CO2 to reduce it to CO, a valuable chemical that can be converted into fertilizer or into a fuel gas that can be used for electric or thermal power generation; (iii) trap particulate matter in the bed of char to join the ash in the char to form a combined ash which is eventually converted to inert slag; and (iv) filter the mercury through a portion of the char to prevent it from being emitted into the atmosphere.Type: ApplicationFiled: March 13, 2009Publication date: September 16, 2010Inventors: Albert Calderon, Terry James Laubis
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Patent number: 7790926Abstract: Alpha, omega-difunctional aldaramides, in particular diaminoaldaramides, dihydroxyaldaramides, bis(alkoxycarbonylalkyl)aldaramides, and bis(carboxyalkyl)aldaramides, and processes for preparing the aldaramides are provided.Type: GrantFiled: January 31, 2008Date of Patent: September 7, 2010Assignee: E. I. du Pont de Nemours and CompanyInventors: Mark Allen Andrews, Henry Keith Chenault, Garret D. Figuly
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Publication number: 20100218414Abstract: The compounds of general formula (I) wherein: R1 is hydrogen, phenyl, C1-6 alkyl which can be further substituted with R3, R3 is 5- or 6-membered aromatic or heteroaromatic ring system which can be further substituted with benzyl or hydroxyl groups; R2 is OR4, NHR4, R4 is hydrogen, C1-6 alkyl or benzyl n is an integer from 1 to 12 or the salts of compounds mentioned which can form gels with commercial fuels, organic solvents and water.Type: ApplicationFiled: September 4, 2008Publication date: September 2, 2010Inventors: Mladen Zinic, Janja Makarevic
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Publication number: 20100159593Abstract: Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the group consisting of N, O and S; L is any bivalent organic radical capable of linking each Q, such as C, CH, (CH2)l, or {(CH2)i-Y—(CH2)j}k, wherein Y is selected from the group consisting of CH2, an ether, a polyether, an amide, a polyamide, an ester, a sulfide, a urea, a thiourea, a guanidyl, a carbamoyl, a carbonate, a phosphate, a sulfate, a sulfoxide, an imine, a carbonyl, and a secondary amino group and wherein Y is optionally substituted by —X1-L?-X2—Z or —Z; R1-R6, independently of one another, are selected from the group consisting of H, —(CH2)p-D-Z, an alkyl, an alkenyl, an aryl, and an alkyl or alkyl ether optionally substituted by one or more of an alcohol, an aminoalcohol, an amine, an amide, an ether, a polyether, a polyamide, an ester, a mercaptan, an alkylthio, a urea, a thiourea, a guanidyl, or a carbamoyl group, andType: ApplicationFiled: December 15, 2009Publication date: June 24, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Yongliang CHU, Malek Masoud, Gulilat Gebeyehu
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Publication number: 20100152452Abstract: This invention relates to dialdehyde or dinitrile compounds, which are useful for stereoselective synthesis of piperidine, pyrrolidine, and azepane derivatives.Type: ApplicationFiled: December 14, 2009Publication date: June 17, 2010Applicant: TaiGen Biotechnology Co., Ltd.Inventors: Shan-Yen Chou, Chi-Hsin Richard King
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Publication number: 20100113279Abstract: Novel bis(dialkylamide) compounds having the formula: R2R3NOC—R1a—CONR4R5 are particularly useful solvents, for example in plant-protection formulations.Type: ApplicationFiled: December 19, 2007Publication date: May 6, 2010Inventors: Jean-Manuel Mas, Valerio Bramati, Massimo Guglieri, Wagner Celio Ferraz Lourenco
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Publication number: 20100109195Abstract: Release agents with increased affinity toward nano-imprint lithography template surfaces interact strongly with the template during separation of the template from the solidified resist in a nano-imprint lithography process. The strong interaction between the surfactant and the template surface reduces the amount of surfactant pulled off the template surface during separation of a patterned layer from the template in an imprint lithography cycle. Maintaining more surfactant associated with the surface of the template after the separation of the patterned layer from the template may reduce the amount of surfactant needed in a liquid resist to achieve suitable release of the solidified resist from the template during an imprint lithography process. Strong association of the release agent with the surface of the template facilitates the formation of ultra-thin residual layers and dense fine features in nano-imprint lithography.Type: ApplicationFiled: November 4, 2009Publication date: May 6, 2010Applicant: MOLECULAR IMPRINTS, INC.Inventors: Frank Y. Xu, Weijun Liu
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Publication number: 20100080880Abstract: The present invention concerns geranylamine derivates of oxalic acid, use of the same as flavorings and certain mixtures, compositions, preparations and semi-finished goods containing one or more such compounds.Type: ApplicationFiled: September 23, 2009Publication date: April 1, 2010Applicant: SYMRISE GmbH & Co. KGInventors: Michael Backes, Jan Looft
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Patent number: 7638650Abstract: A compound of formula (I): wherein k is 1 or 2; Y is —CH2CH(CF3)2 or —(CH2)nCF; X is hydrogen, —(CH2)nRf, or —C(O)[CF(A)]p-B—Rf, wherein B is a covalent bond, —O— or —(CH2)m—; A is —F or —CF3; and each Rf is independently C1 to C6 perfluorinated alkyl, optionally interrupted by one or more oxygens; Ro is Ro1 or is an alkyl having from about 10 to about 100 carbon atoms, interrupted or substituted by one or more hydrophilic groups; R is hydrogen or a C1 to C4 alkyl; and Ro1 is an aliphatic group of from about 10 to about 100 carbon atoms, interrupted by about from about 5 to about 50 ether oxygens; provided that 1) when Y is —(CH2)nRf, Ro is Ro1; 2) when X is hydrogen, Y is —CH2CH(CF3)2; and 3) when X is —(CH2)nRf and Y is —(CH2)nRf, Ro is Ro1.Type: GrantFiled: August 6, 2007Date of Patent: December 29, 2009Assignee: E.I. du Pont de Nemours and CompanyInventor: Weiming Qiu
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Publication number: 20090314639Abstract: The present invention relates to means and devices for electro-filtration of molecules. The membranes comprise N-acryloyl-tris(hydroxymethyl)aminomethane (NAT) covalently linked to a support. The invention further encompasses compositions comprising an isoelectric buffer covalently bound to N-acryloyl-tris(hydroxymethyl)aminomethane (NAT). In particular, the present invention relates to membranes and devices allowing an isoelectric filtration of molecules in solution.Type: ApplicationFiled: September 17, 2007Publication date: December 24, 2009Inventors: Michel Daniel Faupel, Jan Van Oostrum
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Publication number: 20090305196Abstract: A hardenable dental composition that includes a polymerizable component and an organogelator.Type: ApplicationFiled: September 12, 2007Publication date: December 10, 2009Inventors: Naimul Karim, Todd D. Jones, Kevin M. Lewandowski, Bradley D. Craig, Sumita B. Mitra, Jie Yang
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Patent number: 7612236Abstract: It is provided that a method for producing an optically active bisamidoalcohol compound represented by the formula (3): wherein R1 represents a C1-6 alkyl group, an optionally substituted phenyl group, an optionally substituted aralkyl group or a hydrogen atom, or two R1s, which are bonded to the same carbon atom, are bonded to form a ring together with the carbon atom to which they are bonded, R2 represents a C1-6 alkyl group, an optionally substituted phenyl group, a 1-naphthyl group, a 2-naphthyl group or an optionally substituted aralkyl group, R3 and R4 are the same or different, and each represents a hydrogen atom or C1-3 alkyl group, m represents an integer of 0 to 2, and * represents an asymmetric center, which comprises reacting an optically active aminoalcohol compound represented by the formula (1): wherein R1, R2 and * are as defined above, with a diester compound represented by the formula (2): wherein R3, R4 and m are as defined above and R5 represents a C1-3 alkyl group,Type: GrantFiled: December 21, 2004Date of Patent: November 3, 2009Assignee: Sumitomo Chemical Company, LimitedInventor: Makoto Itagaki
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Publication number: 20090143583Abstract: Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the group consisting of N, O and S; L is any bivalent organic radical capable of linking each Q, such as C, CH, (CH2)l, or {(CH2)i-Y—(CH2)j}k, wherein Y is selected from the group consisting of CH2, an ether, a polyether, an amide, a polyamide, an ester, a sulfide, a urea, a thiourea, a guanidyl, a carbamoyl, a carbonate, a phosphate, a sulfate, a sulfoxide, an imine, a carbonyl, and a secondary amino group and wherein Y is optionally substituted by —X1-L?-X2-Z or -Z; R1-R6, independently of one another, are selected from the group consisting of H, —(CH2)p-D-Z, an alkyl, an alkenyl, an aryl, and an alkyl or alkyl ether optionally substituted by one or more of an alcohol, an aminoalcohol, an amine, an amide, an ether, a polyether, a polyamide, an ester, a mercaptan, an alkylthio, a urea, a thiourea, a guanidyl, or a carbamoyl group, andType: ApplicationFiled: January 14, 2009Publication date: June 4, 2009Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Yongliang CHU, Malek MASOUD, Gulilat GEBEYEHU
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Publication number: 20090047435Abstract: One aspect of the invention is a compound of formula (I) Ro-[L-(CqH2qS)pCrH2rRf]2??(I) wherein Ro is a divalent organic group having 2 to 40 carbon atoms; L is a linking group selected from —NHC(O)NH— or —C(O)NH— wherein the left side of the linking group is bonded to Ro; p is an integer of 0 or 1; q is an integer of 2 to 10; r is an integer of 1 to 10; and Rf is a linear or branched C1-C6 perfluoroalkyl group. Another aspect of the invention is a composite material comprising a porous support and a porous nanoweb, wherein said porous nanoweb comprises fibrous structures of between about 10 nm and about 1000 nm effective average fiber diameter as determined with electron microscopy; said fibrous structures being comprised of one or more compositions of formula (I). Another aspect of the invention is a method for making a composite material comprising a porous support and a porous nanoweb.Type: ApplicationFiled: August 13, 2007Publication date: February 19, 2009Inventors: Keith Ward Hutchenson, Anilkumar Raghavanpillai, Stefan Reinartz
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Publication number: 20080221218Abstract: The present invention relates to synthetic receptors, products and methods which are useful in relation to the binding of phosphates for example in water purification and renal dialysis systems.Type: ApplicationFiled: August 15, 2006Publication date: September 11, 2008Applicant: The University of YorkInventors: Hubertus Franciscus Martinus Nelissen, David Kelham Smith
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Patent number: 7399879Abstract: A process for the preparation of a monoalkylidene substituted 1,4-dions derivatives of formula (Ia) or (Ib) or a mixture of (Ia) and (Ib): wherein: R1, R2 and R3, equal to or different from each other, are hydrogen atoms or C1–C20 hydrocarbon groups: T1 and T2, equal to or different from each other, are OR4, R4, NR42, SR4 or PR42; or T1 and T2 can be fused in an oxygen atom or a NR4 group; said process comprises the step of reacting a compound of formula (II) with a compound of formula (IIIa) or (IIIb) in the presence of at least one equivalent with respect to the compound of formula (IIIa) or (IIIb) of a carbonate of metal M or of a compound of formula MTj such as K2CO3 or KHCO3Type: GrantFiled: July 25, 2003Date of Patent: July 15, 2008Assignee: Basell Poliolefine Italia S.p.A.Inventors: Yuri V. Gulevich, Giampiero Morini
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Publication number: 20080113172Abstract: Partially fluorinated amino acid derivatives are provided that are useful as organogelators and surface treatment materials to provide oil- and water-repellency properties to substrates. Also provided are composite materials comprising a porous support and a porous nanoweb. The porous nanoweb contains fibrous structures of about 10 nm to about 1000 nm effective average fiber diameter.Type: ApplicationFiled: November 13, 2006Publication date: May 15, 2008Inventors: Erick Jose Acosta, Anilkumar Raghavanpillai, Sheng Peng, Stefan Reinartz
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Patent number: 7351862Abstract: Alpha, omega-difunctional aldaramides, in particular diaminoaldaramides, dihydroxyaldaramides, bis(alkoxycarbonylalkyl)aldaramides, and bis(carboxyalkyl)aldaramides, and processes for preparing the aldaramides are provided.Type: GrantFiled: February 23, 2006Date of Patent: April 1, 2008Assignee: E.I. du Pont de Nemours and CompanyInventors: Mark Allen Andrews, Henry Keith Chenault, Garret D. Figuly
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Patent number: RE41151Abstract: In accordance with the present invention, there are provided normal modified forms of nonsteroidal anti-inflammatory drugs. Modified NSAIDs according to the invention provide a new class of anti-inflammatory agent which provide the therapeutic benefits of NSAIDs while causing a much lower incidence of side-effects then typically observed with such agents.Type: GrantFiled: August 20, 2008Date of Patent: February 23, 2010Assignee: Medinox, Inc.Inventors: Ching-San Lai, Tingmin Wang