Thiooxamides (i.e., Hnh-c(=s)-c(=x)-hnh, Wherein X Is S Or O And Substitution May Be Made For Hydrogen Only) Patents (Class 564/77)
  • Publication number: 20110245262
    Abstract: Disclosed are compounds and methods of using compounds of the invention for treating a subject with a proliferative disorder, such as cancer, and methods for treating disorders responsive to Hsp70 induction and/or natural killer induction. Also, disclosed are pharmaceutical compositions comprising compounds of the invention and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: August 20, 2007
    Publication date: October 6, 2011
    Inventors: Lijun Sun, Keizo Koya, Shoujun Chen, Zachary Demko, Zhi-Qiang Xia
  • Patent number: 7981954
    Abstract: Methods for controlling atmospheric corrosion of a metallic surface including coating the metallic surface with a coating material containing at least one compound having at least one thioamide group.
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: July 19, 2011
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Fischer, Monica Fernandez Gonzalez, Marc Schroeder, Konrad Roschmann, Alexander Goethlich, Hermann Bergmann, Guido Vandermeulen
  • Publication number: 20040171079
    Abstract: The invention relates to a resin-bound synthesis process for the preparation of chemical compounds of the formula (I)
    Type: Application
    Filed: March 12, 2004
    Publication date: September 2, 2004
    Inventors: Klaus Haaf, Lothar Willms
  • Patent number: 5393913
    Abstract: The present invention relates to N-carbonyl anilines which are intermediates for the preparation of pesticidal 1-aryl imidazoles and to processes for making them.
    Type: Grant
    Filed: March 3, 1993
    Date of Patent: February 28, 1995
    Assignee: Rhone-Poulenc Inc.
    Inventor: Thierry Aubert
  • Patent number: 5220022
    Abstract: Disclosed are novel compounds of the formula ##STR1## wherein: R is ##STR2## where Ph is phenyl, or ##STR3## X is --NR.sub.5 R.sub.6 or --OR.sub.7 ; R.sub.1 and R.sub.2 are independently hydrogen, methyl, ethyl, cyclohexyl, ##STR4## butyl, or heptyl; R.sub.4 is o-phenylene or p-phenylene and R.sub.4 can be alkyl- halo- or alkoxy- substituted;R.sub.3 is hydrogen;R.sub.5, R.sub.6, and R.sub.7 are independently hydrogen, methyl, ethyl, tert-butyl, isobutyl, butyl, alkoxy, acyl, acylamino, aryl, amino, cyclohexyl, aminoalkyl and substituted or unsubstituted phenylamino;Y is sulfur and oxygen atom; and n is zero or 1; provided n=1 when Y is sulfur.
    Type: Grant
    Filed: January 28, 1991
    Date of Patent: June 15, 1993
    Assignee: International Paper Co.
    Inventors: Bruce M. Resnick, Allan J. Wexler
  • Patent number: 5041654
    Abstract: This invention relates to the synthesis of N-(monosubstituted)dithiooxamides by the transamination of dithiooxamide. Preferred methods, according to the present invention, take advantage of the discovery that yields of N-(monosubstituted)dithiooxamides can be improved in the Wallach Reaction by: controlling the temperature of the reaction mixture; optimizing the initial concentration of the reactants; adding an effective amount of acid in the quenching or processing procedure; and/or, optionally, adding an effective amount of certain nitrogen bases to the reaction mixture.
    Type: Grant
    Filed: November 17, 1989
    Date of Patent: August 20, 1991
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: David B. Olson, Robert J. Lokken, Roger A. Mader, Jacqueline M. Furlong
  • Patent number: 4997980
    Abstract: Disclosed are novel compounds of the formula: ##STR1## wherein: X=--NR.sub.5 R.sub.6, or --OR.sub.7 ;R.sub.1 and R.sub.2 are independently hydrogen, substituted or unsubstituted alkyl, haloalkyl, hydroxyalkyl alkoxyalkyl, alkylaminoalkyl or arylalkyl having up to 18 carbons, cycloalkyl; phenyl or naphthyl; alkylphenyl, cyanophenyl, halophenyl or alkoxyphenyl substituents;R.sub.3 is hydrogen, benzyl, alkoxybenzyl, halobenzyl or alkylbenzyl, provided that if neither R.sub.1 nor R.sub.2 is hydrogen, then R.sub.3 is hydrogen;R.sub.4 is a divalent aromatic group which is substituted or unsubstituted;R.sub.5, R.sub.6 and R.sub.7 are independently hydrogen, alkyl, hydroxyalkyl, haloalkyl, alkoxyalkyl, alkylaminoalkyl, acylaminoalkyl, aminoalkyl or phenylalkyl having up to 12 carbons; a cycloalkyl substitutent; phenyl or naphthyl; an alkylphenyl, cyanophenyl, halophenyl or alkoxyphenyl substituent;Furthermore, either R.sub.1 and R.sub.3 or R.sub.1 and R.sub.
    Type: Grant
    Filed: April 17, 1989
    Date of Patent: March 5, 1991
    Assignee: Anitec Image Corporation
    Inventors: Bruce M. Resnick, Allan J. Wexler
  • Patent number: 4301159
    Abstract: A compound of the formula: ##STR1## wherein R is alkyl;R.sup.1 is hydrogen, halogen, alkyl or alkoxy;R.sup.2 is amino, alkanoyl, ##STR2## R.sup.3 is alkyl or dialkylamino; andR.sup.4 is hydrogen or alkylwith the proviso that when R.sup.2 is amino or alkanoyl, R.sup.1 is alkyland or a pharmaceutically acceptable acid addition salt thereof, being useful as gastric disorder remedies or antiemetics are provided via several routes.
    Type: Grant
    Filed: June 20, 1980
    Date of Patent: November 17, 1981
    Assignee: Shionogi & Co., Ltd.
    Inventors: Masaru Ogata, Hiroshi Matsumoto, Katsumi Hirose, Masami Eigyo
  • Patent number: 4244604
    Abstract: A composition capable of reducing image-offset when used in combination with color-forming compounds which are capable of forming colored images with color-developing coreactants. The composition comprises an aliphatic tertiary amine image-offset control agent. Color-forming compounds such as dithiooxamide, dithiooxamide derivatives and certain aromatic substituted hydrazones, may also be included in the composition. The invention when employed in the art of carbonless paper enables the production of dark, black images in areas of a paper substrate containing color-forming compositions and transition metal color-developing compositions, without image-offsetting in areas not containing both the color-forming compound and the color-developing compound, even upon stacking color-forming compound containing sheets on top of color-developing compound containing sheets.
    Type: Grant
    Filed: May 23, 1979
    Date of Patent: January 13, 1981
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: William J. Fraser