Plural Sulfonamide Groups Containing Or Containing Plural Sulfonyls Bonded Directly To The Same Nitrogen Patents (Class 564/82)
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Publication number: 20110195945Abstract: Compositions and methods of treating or preventing disease or injury to a human patient or biological material undergoing ischemic or hypoxic conditions.Type: ApplicationFiled: February 11, 2011Publication date: August 11, 2011Applicant: Ikaria, Inc.Inventors: Fuqiang Ruan, Edward A. Wintner, Thomas L. Deckwerth
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Publication number: 20110159431Abstract: The present invention provides photoacid generators for use in chemically amplified resists and lithographic processes using the same.Type: ApplicationFiled: June 10, 2009Publication date: June 30, 2011Inventors: Kenneth E. Gonsalves, Mingxing Wang
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Publication number: 20110102528Abstract: An embodiment of the composition contains any of compounds of the formula A-LG in which A represents any of residues of general formula (A-1) below and LG represents any of groups that are cleaved to generate acids of the formula A-H when acted on by an acid. The composition further contains at least one of a compound that generates an acid when exposed to actinic rays or radiation and a compound that generates an acid when heated.Type: ApplicationFiled: October 28, 2010Publication date: May 5, 2011Applicant: FUJIFILM CorporationInventors: Tomotaka TSUCHIMURA, Takeshi Kawabata, Takayuki Ito
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Patent number: 7901871Abstract: A composition containing a photoacid generator monomer and surfactant, and a method for synthesizing a compound on a substrate using the composition are provided. The method includes bonding a layer of first molecules having an acid labile protecting group to a solid substrate; coating a layer of the photoacid generator monomer composition according to the present invention on the layer of first molecules; exposing the composition layer to light and then heat-treating to remove the acid labile protecting group from the first molecules corresponding to the exposed portion; washing and removing the composition layer from the exposed and unexposed portions; and bonding second molecules to the exposed first molecules.Type: GrantFiled: January 9, 2008Date of Patent: March 8, 2011Assignee: Samsung Electronics Co., Ltd.Inventors: Sung-ouk Jung, Seung-ju Seo, Jae-chan Park
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Publication number: 20110052492Abstract: This invention relates to new radiohalogenated benzamide derivatives and their use in tumor diagnosis and tumor therapy. The radiohalogenated benzamide derivatives according to the invention exhibit novel and especially advantageous properties, in particular with respect to tumor concentration and retardation, liver concentration and blood accumulation. The radiation-therapy doses to be achieved in the tumor, compared to healthy body tissue, are advantageous for the compounds according to the invention.Type: ApplicationFiled: November 3, 2010Publication date: March 3, 2011Inventors: Matthias FRIEBE, Peter Muschick, Andreas Huth
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Publication number: 20110054190Abstract: Disclosed is a technology for enabling an efficient asymmetric Michael addition reaction which does not require a large amount of a malonic ester, while having a short reaction time. Specifically disclosed is a catalyst which is composed of MX2 (wherein M is Be, Mg, Ca, Sr, Ba or Ra and X is an arbitrary group) and a compound represented by general formula [I]. [In the formula, R7, R8, R9 and R10 each represents a substituted cyclic group or an unsubstituted cyclic group.Type: ApplicationFiled: January 28, 2009Publication date: March 3, 2011Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCYInventors: Shu Kobayashi, Magno Agostinho, Uwe Schneider, Miyuki Yamaguchi
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Publication number: 20110034716Abstract: The present invention provides a method for producing fluorosulfonylimides more safely, rapidly and efficiently, which enables suppression of production of by-products, and fluorosulfonylimides. The method for producing a fluorosulfonylimide salt of the present invention includes a step of reacting a fluoride compound containing at least one element selected from the group consisting of elements of Group 11 to Group 15 and Period 4 to Period 6 (excluding arsenic and antimony) with a compound represented by the following general formula (I) to give a fluorosulfonylimide salt represented by the general formula (II): wherein R1 denotes at least one element selected from the group consisting of elements of Group 11 to Group 15 and Period 4 to Period 6 (excluding arsenic and antimony); R3 denotes fluorine, chlorine or a fluorinated alkyl group having 1 to 6 carbon atoms; R4 denotes fluorine or a fluorinated alkyl group having 1 to 6 carbon atoms; and m denotes an integer of 2 or 3.Type: ApplicationFiled: March 30, 2009Publication date: February 10, 2011Inventors: Yasunori Okumura, Kazuo Takei, Shimpei Sato, Yuichi Sato
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Publication number: 20110034461Abstract: The invention relates to novel compounds of formula I where R1, R2, R3, R4, R5, R9, Ar, Q1, Q2 and Q3 are each as defined below. The compounds of the formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of the formula I and to the use thereof as a medicament.Type: ApplicationFiled: August 5, 2010Publication date: February 10, 2011Applicant: sanofi-aventisInventors: Uwe HEINELT, Volkmar WEHNER, Matthias HERRMANN, Karl SCHOENAFINGER, Henning STEINHAGEN
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Publication number: 20110027716Abstract: According to one embodiment, an actinic-ray- or radiation-sensitive resin composition includes any of the compounds (A) of general formula (I) below that when exposed to actinic rays or radiation, generates an acid and a resin (B) whose rate of dissolution into an alkali developer is increased by the action of an acid. (The characters used in general formula (I) have the meanings mentioned in the description.Type: ApplicationFiled: July 9, 2010Publication date: February 3, 2011Applicant: FUJIFILM CORPORATIONInventors: Shuhei YAMAGUCHI, Akinori Shibuya
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Publication number: 20110027179Abstract: This invention relates to new radiohalogenated benzamide derivatives and their use in tumor diagnosis and tumor therapy. The radiohalogenated benzamide derivatives according to the invention exhibit novel and especially advantageous properties, in particular with respect to tumor concentration and retardation, liver concentration and blood accumulation. The radiation-therapy doses to be achieved in the tumor, compared to healthy body tissue, are advantageous for the compounds according to the invention.Type: ApplicationFiled: October 14, 2010Publication date: February 3, 2011Inventors: Matthias FRIEBE, Peter Muschick, Andreas Huth
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Patent number: 7875746Abstract: A photosensitive composition comprising: (A) a compound capable of generating a compound having a specific structure upon irradiation with actinic rays or radiation, a pattern forming method using the photosensitive composition, and a compound capable of generating a compound having a specific structure upon irradiation with actinic rays or radiation.Type: GrantFiled: May 23, 2006Date of Patent: January 25, 2011Assignee: FUJIFILM CorporationInventor: Kenji Wada
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Publication number: 20100331321Abstract: The invention provides compounds of formula (I) wherein R1,R3,L1,L2,G1,G2, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1.Type: ApplicationFiled: December 18, 2008Publication date: December 30, 2010Applicant: ASTRAZENECA ABInventors: Johan Bylund, Maria E. Ek, Ylva Gravenfors, Jorg Holenz, Alexander Minidis, Gunnar Nordvall, Daniel Sohn, Karl S.A. Vallin, Jenny Viklund, Stefan Von Berg
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Patent number: 7838684Abstract: The present invention relates to compositions of matter that are ionic liquids, the compositions comprising any of eleven cations combined with any of three fluorinated sulfonated anions. Compositions of the invention should be useful as solvents and, perhaps, as catalysts for many reactions, including aromatic electrophilic substitution, nitration, acylation, esterification, etherification, oligomerization, transesterification, isomerization and hydration.Type: GrantFiled: May 27, 2009Date of Patent: November 23, 2010Assignee: E.I. du Pont de Nemours and CompanyInventors: Mark Andrew Harmer, Christopher P. Junk, Jemma Vickery
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Publication number: 20100233629Abstract: A photosensitive composition comprising: (A) a compound capable of generating a compound having a specific structure upon irradiation with actinic rays or radiation, a pattern forming method using the photosensitive composition, and a compound capable of generating a compound having a specific structure upon irradiation with actinic rays or radiation.Type: ApplicationFiled: April 13, 2010Publication date: September 16, 2010Applicant: FUJIFILM CorporationInventor: Kenji Wada
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Patent number: 7781614Abstract: The invention relates to a method of treating an impure organic composition of ammonium imide, one of the substituents of which imide ion is a sulfonyl carried by a perhalogenated, advantageously perfluorinated carbon, characterized in that said composition is subjected to a step of liquid-liquid extraction by means of an aqueous phase and containing, as impurity, at least one of the chemical species chosen from halides, sulfonates and sulfinates, in particular those whose sulfur is carried by a perhalogenated carbon.Type: GrantFiled: February 14, 2003Date of Patent: August 24, 2010Assignee: Rhodia ChimieInventor: Bernard Besson
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Patent number: 7714167Abstract: The present invention relates to the synthesis of chiral epoxides via a catalytic asymmetric oxidation of olefins. Additionally, the methodology provides a method of asymmetrically oxidizing sulfides and phosphines. This asymmetric oxidation employs a catalyst system composed of a metal and a chiral bishydroxamic acid ligand, which, in the presence of a stoichiometric oxidation reagent, serves to asymmetrically oxidize a variety of substrates.Type: GrantFiled: January 22, 2007Date of Patent: May 11, 2010Assignees: University of Chicago, Japan Science & Technology AgencyInventors: Hisashi Yamamoto, Arindrajit Basak, Wei Zhang
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Patent number: 7695637Abstract: Disclosed are a slurry composition for chemical mechanical polishing and a precursor composition thereof. The polishing slurry composition includes deionized water, abrasive particles, a pH-adjusting agent and a surfactant, wherein the surfactant includes two or more ionic moieties and two or more lipophilic groups. The polishing slurry composition can polish convex surfaces of a semiconductor having a step height at a higher rate than the polishing rate for concave surfaces acting as polishing stop layers of the semiconductor so that the polishing can be self-stopped, reduces the occurrence of surface defects after the polishing process, and has a high degree of polishing planarization and good dispersion stability.Type: GrantFiled: December 22, 2006Date of Patent: April 13, 2010Assignee: Cheil Industries Inc.Inventors: Tae Won Park, In Kyung Lee, Byoung Ho Choi
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Patent number: 7678941Abstract: The present invention provides polyoxyalkylene ammonium imide or methide salts and their use as antistatic agents. Another embodiment provides articles comprising these salts, and processes for making and using these salts.Type: GrantFiled: July 23, 2007Date of Patent: March 16, 2010Assignee: 3M Innovative Properties CompanyInventors: Patricia M. Savu, William M. Lamanna, Thomas P. Klun
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Patent number: 7601480Abstract: The present application relates to a compound of formula where X is selected from the group CF3SO3, C4F9SO3, N(SO2C2F5)2, N(SO2CF3SO2C4F9), N(SO2C3F7)2, N(SO2C4F9)2, CF3CHFO(CF2)2SO3, and CH3CH2CH2O(CF2)4SO3. A photoresist composition comprising a polymer containing an acid labile group, the above compounds, and one or more additional photoacid generators is also provided for.Type: GrantFiled: December 20, 2006Date of Patent: October 13, 2009Assignee: AZ Electronic Materials USA Corp.Inventors: M. Dalil Rahman, Takanori Kudo
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Patent number: 7592375Abstract: Disclosed herein is an ion conductive polymer comprising a unit represented by Formula (1) below: —SO2[N?SO2(M+)]X1-??(1) wherein X1 is an integer greater than 1, and M+ is H+ or Li+. Further disclosed is an imide monomer represented by Formula (A) below: Z1-SO2[N?SO2M+]Y-Z2 ??(A) wherein Y is an integer of 2 or greater, Z1 is OH, F, Cl, Br, I or NZ3Z4 (in which Z3 and Z4 are each independently H, M or SiMe3, and M is a metal element), Z2 is OH, F, Cl, Br, I or NZ3Z4 (in which Z3 and Z4 are each independently H, M or SiMe3, and M is a metal element), and M+ is H+ or Li+.Type: GrantFiled: May 2, 2006Date of Patent: September 22, 2009Assignee: Kabushiki Kaisha Toyota Chuo KenkyushoInventors: Greg Shafer, Masaya Kawasumi, Yoichi Hosokawa, Naoki Hasegawa, Satoru Yamamoto, Kenji Imai, Yuko Murayama, Shiaki Hyodo
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Patent number: 7547716Abstract: A medicament for enhancing an effect of a cancer therapy based on a mode of action of DNA injury, which comprises as an active ingredient a compound represented by the general formula (I) or a physiologically acceptable salt thereof: wherein R represents an aryl-substituted alkyl group, an heteroaryl-substituted alkyl group, a cycloalkyl-substituted alkyl group, or a cyclic hydrocarbon group wherein said cyclic hydrocarbon group may be saturated, partly saturated, or aromatic; or Z may bind to R to form a cyclic structure, Z represents a hydrogen atom or a C1 to C6 alkyl group. The medicament enhanced the effect of the cancer therapy and decreases a dose of an anticancer agent and/or radiation, and therefore, can reduce side effects resulting from the cancer therapy.Type: GrantFiled: June 7, 2002Date of Patent: June 16, 2009Assignee: Institute of Medicinal Molecular Design, Inc.Inventors: Susumu Muto, Masayuki Komukai, Akiko Itai
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Patent number: 7531577Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein Ar, X, m, R1, R2 are as defined herein. Also provided are methods for preparing, compositions comprising, and methods for using compounds of formula I for treatment of 5-HT6-mediated diseases.Type: GrantFiled: June 20, 2007Date of Patent: May 12, 2009Assignee: Roche Palo Alto LLCInventors: Ralph New Harris, III, James M. Kress, David Bruce Repke, Russell Stephen Stabler
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Publication number: 20090105473Abstract: The invention is directed to pyrro[1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.Type: ApplicationFiled: November 6, 2008Publication date: April 23, 2009Applicant: ANADYS PHARMACEUTICALS, INC.Inventors: Stephen E. Webber, Frank Ruebsam, Martin Tran, Peter Dragovich, Liansheng Li, Douglas E. Murphy, David Kucera, Zhongxiang Sun, Chinh V. Tran
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Publication number: 20080275221Abstract: Novel conjugates of busulfan and novel busulfan immunogens derived from ?-substituted derivatives of busulfan and antibodies generated by these busulfan linked immunogens are useful in immunoassays for the quantification and monitoring of busulfan in biological fluids.Type: ApplicationFiled: July 9, 2008Publication date: November 6, 2008Inventors: Salvatore J. Salamone, Jodi Blake Courtney, Shu He
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Publication number: 20080220371Abstract: A photosensitive composition comprises: (A) a compound capable of generating an acid represented by formula (I) upon irradiation with actinic ray or radiation; and (B) a resin that decomposes by the action of an acid to its increase solubility in an alkali developer wherein Ra represents an alkyl group substituted with a fluorine atom, or an aryl group substituted with a fluorine atom or a group having a fluorine atom; Rb represents an alkyl group not substituted with a fluorine atom on ?-position of the alkyl group, or an aryl group not substituted with a fluorine atom or a group having a fluorine atom.Type: ApplicationFiled: March 10, 2008Publication date: September 11, 2008Applicant: FUJIFILM CORPORATIONInventor: Kunihiko KODAMA
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Patent number: 7411002Abstract: Certain lipophilic polycationic sulfonamides are provided and are useful for treating various diseases or conditions and particularly sepsis.Type: GrantFiled: June 7, 2006Date of Patent: August 12, 2008Assignees: The University of Kansas, Mediquest Therapeutics, Inc.Inventors: Mark R. Burns, Sunil A. David, Scott A. Jenkins
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Patent number: 7378034Abstract: The invention relates to an ionic compound corresponding to the formula [R1X1(Z1)-Q?-X2(Z2)-R2]m Mm+ in which Mm+ is a cation of valency m, each of the groups Xi is S=Z3, S=Z4, P—R3 or P—R4; Q is N, CR5, CCN or CSO2R5, each of the groups Zi is ?O, ?NC?N, ?C(C?N)2, ?NS(=Z)2R6 or ?C[S(=Z)2R6]2, each of the groups Ri, is Y, YO—, YS—, Y2N— or F, Y represents a monovalent organic radical or alternatively Y is a repeating unit of a polymeric frame. The compounds are useful for producing ion conducting materials or electrolytes, as catalysts and for doping polymers.Type: GrantFiled: January 17, 2007Date of Patent: May 27, 2008Assignees: Universite de Montreal, Centre National de la Recherche Scientifique, Institute of Organic Chemistry National Academy of Sciences of UkraineInventors: Michel Armand, Christophe Michot, Yurii Yagupolskii, Lev Yagupolskii, Andrej Bezdudny, Natalya Kondratenko
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Patent number: 7265130Abstract: The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof.Type: GrantFiled: December 30, 2003Date of Patent: September 4, 2007Assignee: Shionogi & Co., Ltd.Inventors: Yasuyuki Kawanishi, Hideyuki Takenaka, Kohji Hanasaki, Tetsuo Okada
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Patent number: 7262223Abstract: The present invention relates to the use of amidine compounds in the treatment of amyloid-related diseases. In particular, the invention relates to a method of treating or preventing an amyloid-related disease in a subject comprising administering to the subject a therapeutic amount of an amidine compound.Type: GrantFiled: January 23, 2004Date of Patent: August 28, 2007Assignee: Neurochem (International) LimitedInventors: Xianqi Kong, Xinfu Wu, David Migneault
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Patent number: 7164041Abstract: A gemini surfactant represented by the formula: wherein: each Rf independently represents perfluorobutyl or perfluoropropyl; each R1 independently represents alkyl having from 1 to 6 carbon atoms; L1 and L2 represent alkylene having from 2 to 18 carbon atoms; each R represents alkyl having from 1 to 6 carbon atoms; Z represents an organic divalent linking group; and nXm? represents an anion or anions having a charge m, wherein m and n are independently 1 or 2, and wherein the product of n and m is 2. Aqueous compositions containing the gemini surfactant are also disclosed.Type: GrantFiled: November 17, 2005Date of Patent: January 16, 2007Assignee: 3M Innovative Properties CompanyInventors: George G. I. Moore, Michael S. Terrazas
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Patent number: 7091219Abstract: Bis-sulfonamido hydroxyethylamino compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to retroviral protease inhibiting compounds of the formula: or a pharmaceutically acceptable salt, prodrug or ester thereof, wherein the variables are as defined herein.Type: GrantFiled: April 17, 2003Date of Patent: August 15, 2006Assignee: G. D. Searle & Co.Inventors: John N. Freskos, Daniel P. Getman, John J. Talley, James A. Sikorski
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Patent number: 7071358Abstract: Arylsulfonamidobenzyl alcohols, amines and sulfonamides are provided which are useful in treating lipid disorders, metabolic diseases and cell-proliferative diseases.Type: GrantFiled: January 29, 2003Date of Patent: July 4, 2006Assignee: Amgen Inc.Inventors: Xian Yun Jiao, Frank Kayser, Sharon McKendry, Derek E. Piper, Andrew K. Shiau
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Patent number: 6984756Abstract: The present invention relates to a process for the preparation of a biphenyl compound comprising combining a phenyl boronic acid derivative with an halobenzene derivative in the presence of a suitable additive in a suitable organic solvent with a suitable catalyst and a suitable base.Type: GrantFiled: May 4, 2001Date of Patent: January 10, 2006Assignee: Eli Lilly and CompanyInventors: John Paul Gardner, William David Miller
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Patent number: 6908947Abstract: The present invention relates to compounds of formula I, in which X1, X2, X3, X4, Y1, Y2, Y3, Y4, R(3), R(4) and R(5) have the meanings mentioned in the specification, their preparation and their use, in particular in pharmaceuticals. The compounds effect the potassium channel or the IKs channel opened by cyclic adenosine monophosphate (cAMP) and are outstandingly suitable as pharmaceutical active compounds, for example for the prophylaxis and therapy of cardiovascular disorders, in particular arrhythmias, for the treatment of ulcers of the gastrointestinal region or for the treatment of diarrheal disorders.Type: GrantFiled: October 25, 2001Date of Patent: June 21, 2005Assignee: Aventis Pharma Deutschland GmbHInventors: Joachim Brendel, Hans Jochen Lang, Uwe Gerlach
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Patent number: 6900353Abstract: The present invention provides compounds of formula (I): useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.Type: GrantFiled: September 28, 2001Date of Patent: May 31, 2005Assignee: Eli Lilly and CompanyInventors: Buddy Eugene Cantrell, Winton Dennis Jones, Jr., Timothy Alan Shepherd, Hamideh Zarrinmayeh, Dennis Michael Zimmerman
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Patent number: 6863838Abstract: Zwitterionic imide compounds are provided according to the formula: R1—SO2—N?—SO2—R2+, where R1 and R2+ are any suitable groups. Typically R1 is a highly fluorinated alkane and R2+ contains a quaternary ammonium group or a heteroatomic aromatic group having an cationic nitrogen, such as: pyridiniumyl, pyridaziniumyl, pyrimidiniumyl, pyraziniumyl, imidazoliumyl, pyrazoliumyl, thiazoliumyl, oxazoliumyl, or triazoliumyl. Zwitterionic liquids are provided, typically having melting points of less than 100° C. and typically having a solubility in water of less than 5% by weight.Type: GrantFiled: October 25, 2001Date of Patent: March 8, 2005Assignee: 3M Innovative Properties CompanyInventor: Steven Joseph Hamrock
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Patent number: 6836383Abstract: The object of the invention is to provide a diphenylsquarylium compound which has a sharp minimum value within the wavelength range of from 550 to 610 nm in the light transmittance curve and from which a filter causing no reduction of brightness of the visual field can be obtained when used by containing in a filter for display, and a filter for display which contains this diphenylsquarylium compound. Constructions of the invention are a diphenylsquarylium compound represented by the following general formula (I) and a filter for display which contains this diphenylsquarylium compound.Type: GrantFiled: March 4, 2003Date of Patent: December 28, 2004Assignee: Mitsubishi Chemical CorporationInventors: Tetsuo Ozawa, Yukinari Haraguchi, Tomomi Nakano
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Patent number: 6790990Abstract: Disclosed is a method for the preparation of a fluorosulfonyl imide monomer of the structure represented by formula (IV), wherein X is F or perfluoroalkyl having 1-4 carbons optionally substituted by ether oxygen, M is an alkali or alkaline earth metal when y is respectively 1 or 2, R is aryl, fluoro-aryl, or XCF2-where X is H, halogen, fluorinated or non-fluorinated linear or cyclic alkyl having 1-10 carbons, optionally substituted by one or more ether oxygens. Such monomers are useful for forming ionomers useful in electrochemical applications such as batteries, fuel cells, electrolysis cells, ion exchange membranes, sensors, electrochemical capacitors, strong acid catalysts, and modified electrodes.Type: GrantFiled: June 14, 2002Date of Patent: September 14, 2004Assignee: E. I. du Pont de Nemours and CompanyInventor: Hanne Anna Katherina Blau
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Electrochemically stable onium salts and electrolytes containing such for electrochemical capacitors
Patent number: 6743947Abstract: Based on the discovery that the melting point and solubility of onium salts are affected by the asymmetry of the substitution on cation, and that the branched substituents effectively shield onium cations from electrochemical reduction, new onium salts are synthesized and high performance electrolytes based on these salts for electrochemical capacitor are provided. The composition of the new electrolyte comprises an onium salt or mixture of such onium salts dissolved in aprotic, non-aqueous solvents or mixture of such solvents. The electrolyte is able to perform at high rate of charge/discharge, at low ambient temperatures, and within wide operating voltage, due to the high solubility, low melting temperature, and the improved reduction stability of the new onium cations, respectively.Type: GrantFiled: May 10, 1999Date of Patent: June 1, 2004Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Kang Xu, Shengping Ding, T. Richard Jow -
Patent number: 6727386Abstract: A method is provided for making aromatic-imide and aromatic-methylidynetrissulfonyl species by reaction of aromatic species with a reactant according to formula (I): (X—SO2—)m—QH—(—SO2—R1)n (I) wherein Q is C or N; wherein each X is independently selected from the group consisting of halogens, typically F or Cl; wherein each R1 is independently selected from the group consisting of aliphatic and aromatic groups, which may or may not be saturated, unsaturated, straight-chain, branched, cyclic, heteroatomic, polymeric, halogenated, fluorinated or substituted; wherein m is greater than 0; wherein m+n=2 when Q is N; and wherein m+n=3 when Q is C. Ar may be derived from an aromatic polymeric compound.Type: GrantFiled: October 25, 2001Date of Patent: April 27, 2004Assignee: 3M Innovative Properties CompanyInventor: Steven Joseph Hamrock
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Publication number: 20040063771Abstract: Bis-sulfonamido hydroxyethylamino compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.Type: ApplicationFiled: April 17, 2003Publication date: April 1, 2004Applicant: G.D. Searle & Co.Inventors: John N. Freskos, Daniel P. Getman, John J. Talley, James A. Sikorski
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Patent number: 6706920Abstract: An antistatic composition comprises (a) at least one ionic salt consisting of a nonpolymeric nitrogen onium cation and a weakly coordinating fluoroorganic anion, the conjugate acid of the anion being a superacid; and (b) at least one thermoplastic polymer. The composition exhibits good antistatic performance over a wide range of humidity levels.Type: GrantFiled: December 28, 2001Date of Patent: March 16, 2004Assignee: 3M Innovative Properties CompanyInventors: William M. Lamanna, Thomas P. Klun, Kathleen A. Hachey, Alan D. Fanta
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Patent number: 6693136Abstract: Compounds of formula (I) are novel P2X3 and P2X2/P2X3 containing receptor antagonists and are useful in treating pain, urinary incontinence, and bladder overactivity.Type: GrantFiled: July 26, 2002Date of Patent: February 17, 2004Assignee: Abbott LaboratoriesInventors: Chih-Hung Lee, Meiqun Jiang, Richard A. Perner, Arthur Gomtsyan, Erol K. Bayburt, Guo Zhu Zheng
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Patent number: 6660884Abstract: The present invention relates to compounds useful as catalysts in asymmetric synthesis of chiral compounds, methods for the synthesis of said catalysts, and methods for synthesizing chiral compounds with high enantioselectivity.Type: GrantFiled: March 14, 2003Date of Patent: December 9, 2003Assignee: The Trustees of the University of PennsylvaniaInventor: Patrick J. Walsh
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Patent number: 6646009Abstract: N-(Aryl)-2-arylethenesulfonamides and pharmaceutically acceptable salts and compositions thereof are useful as antiproliferative agents, including, for example, anticancer agents. They are also useful as radioprotective agents.Type: GrantFiled: February 28, 2002Date of Patent: November 11, 2003Assignees: Temple University — Of Commonwealth System of Higher Education, Onconova Therapeutics, Inc.Inventors: E. Premkumar Reddy, M.V. Ramana Reddy, Stanley C. Bell
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Publication number: 20030204034Abstract: Control agents that have an oxygen-nitrogen bond covalently bonded to a thiocarbonyl moiety are provided for living-type free radical polymerization of a wide variety of monomers, particularly vinyl monomers.Type: ApplicationFiled: March 22, 2002Publication date: October 30, 2003Applicant: Symyx Technologies, Inc.Inventors: Dominique Charmot, Han-Ting Chang, Manikandan Jayaraman, Victor Nava-Salgado
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Patent number: 6620858Abstract: Disclosed are thermally-stable, colored, photopolymerizable compounds containing a vinyl group which are capable of being copolymerized with reactive vinyl monomers to produce colored compositions such as polyacrylates, polymethacrylates, polystyrene, etc. The compounds exhibit good thermal stability, fastness (stability) to UV-light, good solubility in the reactive monomers and good color strength.Type: GrantFiled: August 1, 2001Date of Patent: September 16, 2003Assignee: Eastman Chemical CompanyInventors: Michael John Cyr, Max Allen Weaver, Gerry Foust Rhodes, Jason Clay Pearson, Phillip Michael Cook, Jos Simon De Wit, Larry Keith Johnson
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Patent number: 6620933Abstract: A azomethine yellow dye compound of general formula (I): General formula (I) wherein R1 and R2 each independently represent a hydrogen atom or a substituent; R3 represents a substituent; m indicates an integer from 0 to 3; when m is 2 or greater, R3's may be the same or different and may be mutually bonded to form a condensed ring; R3 may be bonded to R1 or R2 to form a condensed ring; R4 represents an aryl group or a heterocyclic group; R5 and R6 each independently represent a hydrogen atom or a substituent; R7 represents a substituent; n indicates an integer from 0 to 4; when n is 2 or greater, R7's may be the same or different and the may be mutually bonded to form a condensed ring; R7 may be bonded to R5 or R6 to form a condensed ring; and R5 and R6 may be bonded to each other to form a ring.Type: GrantFiled: September 26, 2002Date of Patent: September 16, 2003Assignee: Fuji Photo Film Co., Ltd.Inventors: Kiyoshi Takeuchi, Shigeki Uehira
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Patent number: 6608120Abstract: Compounds of the formula: having two double bonds which are activated so that they will take part in a polymerization reaction, the double bonds being sufficiently close together to ensure that cyclopolymerization will preferentially occur. These compounds are used as monomers which preferentially are cyclopolymerized under the influence of ultraviolet or thermal radiation in the production of network polymers, for example coatings or binders.Type: GrantFiled: January 17, 2001Date of Patent: August 19, 2003Assignee: Qinetiq LimitedInventors: Paul E Milne, Keith M Blackwood, Steven M Kelly, Alan W Hall, John W Goodby
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Patent number: 6569882Abstract: Bis-sulfonamido hydroxyethylamino compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to retroviral protease inhibiting compounds of the formula: or a pharmaceutically acceptable salt, prodrug or ester thereof, wherein the variables are as defined herein.Type: GrantFiled: February 19, 2002Date of Patent: May 27, 2003Assignee: G. D. Searle & Co.Inventors: John N. Freskos, Daniel P. Getman, John J. Talley, James A. Sikorski