Abstract: A method of making CF3CH2SH, comprising a step of reacting CF3CH2X, wherein X is halide or tosylate, with MSH, where M is an alkali metal such as Na or K, to yield CF3CH2SH.

Abstract: A golf ball 2 includes a spherical core 4, a mid layer 6, and a cover 8. The core 4 is obtained by crosslinking a rubber composition. The difference between: a hardness H(5.0) at a point which is located at a distance of 5 mm from the central point of the core 4; and a hardness Ho at the central point is 6.0 or greater. The difference between: a hardness H(12.5) at a point which is located at a distance of 12.5 mm from the central point; and the hardness H(5.0) is 4.0 or less. The difference between a hardness Hs at the surface of the core 4 and the hardness H(12.5) is 10.0 or greater. The difference between the hardness Hs and the hardness Ho is 22.0 or greater. There is no zone in which a hardness decreases from the central point to the surface. A Shore D hardness H3 of the cover is greater than a Shore D hardness H2 of the mid layer.

Abstract: The present invention provides N-alkylthio ?-lactams and disulfide compounds (e.g., alkyl-coenzyme A asymmetric disulfides or aryl-alkyl disulfides), compositions containing such compounds, and methods of their use as anti-bacterial agents.

Abstract: A golf ball 2 includes a spherical core 4 and a cover 6 positioned outside the core 4. The core 4 is obtained by crosslinking a rubber composition including 2-naphthalenethiol. The difference between: a hardness H(5.0) at a point which is located at a distance of 5 mm from the central point of the core 4; and a hardness Ho at the central point is 6.0 or greater. The difference between: a hardness H(12.5) at a point which is located at a distance of 12.5 mm from the central point; and the hardness H(5.0) is 4.0 or less. The difference between a hardness Hs at the surface of the core 4 and the hardness H(12.5) is 10.0 or greater. The difference between the hardness Hs and the hardness Ho is 22.0 or greater. There is no zone in which a hardness decreases from the central point to the surface.

Abstract: A salt represented by the formula (I) and a resist composition containing the salt are provided, wherein Q1, Q2, L1, ring W1, Re1, Re2, Re3, Re4, Re5, Re6, Re7, Re8, Re9, Re10, Re11, Re12, Re13 and Z are defined in the specification.

Abstract: The present invention provides a salt represented by the formula (I): wherein R1 and R2 each independently represent a fluorine atom or a C1-C6 perfluoroalkyl group, X1 represents a C1-C17 divalent saturated hydrocarbon group in which one or more —CH2— can be replaced by —O— or —CO— and which can have one or more fluorine atoms, R3 represents a hydrogen atom or a methyl group, and Z1+ represents an organic counter cation, and a photoresist composition containing the same.

Abstract: The present invention provides N-alkylthio ?-lactams and disulfide compounds (e.g., alkyl-coenzyme A asymmetric disulfides or aryl-alkyl disulfides), compositions containing such compounds, and methods of their use as anti-bacterial agents.

Abstract: A positive resist composition including a base component (A) which exhibits changed solubility in an alkali developing solution under the action of acid and an acid-generator component (B) which generates acid upon exposure, wherein the acid-generator component (B) includes an acid generator (B1) containing a compound represented by general formula (b1-1) shown below (wherein Z+ represents an organic cation).

Abstract: A salt represented by the formula (I): wherein Q1, Q2, L1, L2, ring W, s, t, R1, R2 and Z+ are defined in the specification.

Abstract: A crosslinked polysulfide-containing cycloaliphatic compound, useful as a crosslinker for filled sulfur-vulcanizable elastomer compositions, is represented by the general formula: [(CaH2a-)mG1(-CbH2bSx—)n?m]o[CcH2c-G2-CdH2dSy—]p[R]q wherein G1 is a saturated, monocyclic aliphatic group of valence n containing from 5 to 12 carbon atoms and optionally containing at least one halogen or a saturated monocyclic silicone [RSiO—]n[R2SiO—]r group of valence n; G2 is a saturated, divalent cyclic aliphatic group of valence 2 containing from 5 to 12 carbon atoms and optionally containing at least one halogen or a saturated monocyclic silicone [RSiO—]n[R2SiO—]r group of valence n; each R independently is a selected from the group consisting of a hydrogen atom, monovalent hydrocarbon of up to 20 carbon atoms and a halogen atom; each occurrence of subscripts a, b, c, d, m, n, o, p, q, x and y independently is an integer wherein a is 2 to 6; b is 2 to 6; c is 1 to 6; d is 1 to 6; m is 1 or 2; n is 3 to 5; o is a positive

Abstract: It is an object of the present invention to provide an aprotic polar solvent mainly useful as a solvent for an electrochemical device, and having a comparatively low melting point and excellent thermal stability. The present invention is a sulfone compound represented by formula (1), wherein, in formula (1), R1 represents a C6-C8 branched-chain alkyl group.

Abstract: The disclosure relates to catalytically active carbocatalysts, e.g., a graphene oxide or graphite oxide catalyst suitable for use in a variety of chemical transformations. In one embodiment, it relates to a method of catalyzing a chemical reaction of an organic molecule by reacting the organic molecule in the presence of a sufficient amount of graphene oxide or graphite oxide for a time and at a temperature sufficient to allow catalysis of a chemical reaction. According to other embodiments, the reaction may be an oxidation reaction, a hydration reaction, a dehydrogenation reaction, a condensation reaction, or a polymerization reaction. Some reactions may include auto-tandem reactions. The disclosure further provides reaction mixtures containing an organic molecule and graphene oxide or graphite oxide in an amount sufficient to catalyze a reaction of the organic molecule.

Abstract: The subject of the present invention is a method for the sulphonylation of a hydroxylated organic compound. The invention relates more particularly to a method for the trifluoromethanesulphonylation of a hydroxylated organic compound. The invention is especially intended for perfluorinated aliphatic hydroxylated compounds. The method of the invention for the sulphonylation of a hydroxylated organic compound is characterized in that it comprises reacting said compound with a sulphonylation agent in an organic medium and in the presence of a heterogeneous inorganic base.

Abstract: Diallylic polysulfides (polysulfanes) are provided with sulfur chain lengths of 9 to 22. Also provided are bis(2-methyl-2-propenyl) polysulfides with sulfur chain lengths of 3 to 22. Also provided are 2-substituted bis(2-propenyl) polysulfides with sulfur chain lengths of 3 to 20. Also provided are the 2-cycloalken-1-yl polysulfides, 2-cyclohexen-1-yl polysulfides and 2-cyclopenten-1-yl polysulfides, with sulfur chain lengths of 3 to 20. Also provided are processes for extending the sulfur chain length of diallylic polysulfides and 2-substituted analogues thereof and allyl methyl polysulfides by bringing such compounds into contact with elemental sulfur and heating, or by mixing with molten sulfur.

Abstract: The invention provides a synthetic and manufacturing process for the preparation of the anticancer drug, fluorapacin, bis(4-fluorobenzyl)trisulfide, and related trisulfide derivatives on large scale. Also provided are processes for the purification and isolation of fluorapacin having high purity and improved stability.

Abstract: Diallylic polysulfides (polysulfanes) are provided with sulfur chain lengths of 9 to 22. Also provided are bis(2-methyl-2-propenyl) polysulfides with sulfur chain lengths of 3 to 22. Also provided are 2-substituted bis(2-propenyl) polysulfides with sulfur chain lengths of 3 to 20. Also provided are the 2-cycloalken-1-yl polysulfides, 2-cyclohexen-1-yl polysulfides and 2-cyclopenten-1-yl polysulfides, with sulfur chain lengths of 3 to 20. Also provided are processes for extending the sulfur chain length of diallylic polysulfides and 2-substituted analogues thereof and allyl methyl polysulfides by bringing such compounds into contact with elemental sulfur and heating, or by mixing with molten sulfur.

Abstract: The invention provides a synthetic and manufacturing process for the preparation of the anticancer drug, fluorapacin, bis(4-fluorobenzyl)trisulfide, and related trisulfide derivatives on large scale. Also provided are processes for the purification and isolation of fluorapacin having high purity and improved stability.

Abstract: A method for treating or preventing injury of a biological material exposed to hypoxic or ischemic conditions comprising contacting the biological material with an effective amount of a compound is disclosed. The compound has the following structure (I): R1—(S)n—R2 ??(I) or a stereoisomer, pharmaceutically acceptable salt or prodrug thereof, wherein R1, R2, and n are as defined herein. Compounds, methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: Novel substituted phenylsulfur trifluorides that act as fluorinating agents are disclosed. Also disclosed are methods for their preparation and methods for their use in introducing one or more fluorine atoms into target substrate compounds. Finally, various intermediate compounds for use in preparing substituted phenylsulfur trifluorides are provided.

Abstract: (Benzenesulfonyl)difluoromethyl anion, in situ generated from difluoromethyl phenyl sulfone and a base, was found to easily undergo nucleophilic substitution reactions (SN2) with primary alkyl halides, elemental halogens, and perfluoroalkyl halides with good selectivity. The formed (benzenesufonyl)difluoromethylalkanes are useful intermediates for the facile preparation of 1,1-difluoro-1-alkenes and difluoromethylalkanes.

Abstract: Disclosed are compositions prepared by free-radical-driven grafting onto hydrocarbons or hydrocarbon ethers of olefinically unsaturated fluorocarbons containing sulfonyl fluoride, fluorosulfonate, fluorosulfonimide, or fluorosulfonyl methide groups, wherein the grafting step is followed by a hydrolysis step in the case of sulfonyl fluoride.

Abstract: The invention is directed to aromatic vinyl sulfide compounds of general formula A(—S—CH?CH2)z, wherein z is in the range of 1-4 and A represents highly halogenated and highly halogenated-deuterated phenyl, biphenyl and naphthalene compounds; highly halogenated and highly halogenated-deuterated biphenyl ethers and thioethers; and highly halogenated and highly halogenated-deuterated unsaturated 5- and 6-member heterocyclic ring systems containing carbon and at least one heteroatom selected from the group consisting of nitrogen, oxygen and sulfur. The aromatic vinyl sulfide compounds of the invention can be used to prepare elements and devices suitable for use in optical communications.

Abstract: Disclosed are compositions prepared by free-radical-driven grafting onto hydrocarbons or hydrocarbon ethers of olefinically unsaturated fluorocarbons containing sulfonyl fluoride, fluorosulfonate, fluorosulfonimide, or fluorosulfonyl methide groups, wherein the grafting step is followed by a hydrolysis step in the case of sulfonyl fluoride.

Abstract: Adhesion promoters for polymer coatings on metals are articulated into at least two head groups connected by a hydrocarbon spacer group. One head group reacts particularly well with polymer molecules. Other head groups form a durable bond with a metal surface. The length of the spacer group is such that a substance deposited in a substance layer on a metallic surface of a body or particle has hydrophobic properties. Suitable adhesion promoters can be sulfur compounds, amino compounds, hydroxyl or carbonyl compounds. A plastic composite body, a compound and a process of preparing a compound are also provided.

Abstract: Benzoic acid derivatives useful as intermediates for the preparation of drugs and agricultural chemicals, particularly compounds having herbicidal activity; and easy and economical processes for the preparation of the same. The processes are specifically those represented by reaction formula for the preparation of compounds represented by general formulae (1) and (6).

Abstract: In the process according to the invention for the manufacture of an alkanesulphonyl chloride RCH2—SO2Cl by oxidative chlorolysis of the corresponding mercaptan RCH2—SH, the mercaptan and water are introduced into the reaction mixture in the form of a dispersion of water in the mercaptan.

Abstract: Compounds of the formula are provided wherein R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen, halogen, hydroxyl, C1-C8 alkyl, C1-C6 alkoxy, nitro, cyano, acetoxy, amino, carboxy, sulfamyl, lower acylsulfamyl and trifluoromethyl. The compounds are inhibitors of cyclooxygenase-2 activity, useful for treating inflammation and cyclooxygenase-mediated disorders.

Abstract: This invention is directed to a process for producing a bishalophenyl disulfide, chracterized by reacting a halothiophenol with an alkali metal hydroxide to obtain an alkali metal halothiophenolate and subsequently converting the halothiophenolate into a disulfide with an oxidizing agent in the presence of a mineral acid. By the process, a bishalophenyl disulfide having a high purity can be industrially produced in high yield.

Abstract: A liquid crystalline sulfur compound exhibiting high anisotropic factor of dipolemoment is provided. A terphenyl skeleton sulfur compound expressed by the general formula (I) is provided. A compound is preferred wherein, in the general formula (I), m is 1, n is 5 to 18, and R3 is an alkyl group wherein the number of carbon atoms is n or fewer than n. A method of synthesisng the terphenyl skeleton sulfur compound wherein, after implementing the synthesizing processes for a methoxy terphenyl derivative, a hydroxy terphenyl derivative, and terphenyl alkyloxy bromide derivative, that bromide derivative and thiourea are caused to react, etc. A self-assembled monolayer made using the terphenyl skeleton sulfur compound noted above is also provided.

Abstract: This invention relates to a process for the preparation of aromatic disulfides represented by the formula (II): Yn—Ar—S—S—Ar—Yn  (II) wherein Ar represents a hydrocarbon aromatic ring group; Y represents a monovalent electrophilic group, and when n is 2 or more, a plural number of Y's may be the same or different from each other; and n is an integer of 1 to 12, which comprises allowing (A) an aromatic thioether represented by the formula (I): Yn—Ar—S—R  (I) wherein Y, Ar and n have the same meanings as defined above; and R represents a monovalent hydrocarbyl group selected from the group consisting of a monovalent tertiary hydrocarbyl group, and benzyl group and a monovalent secondary hydrocarbyl group derived from benzyl group; to react with (B) at least one of the following (1) to (4): (1) bromine; (2)(a) hydrogen bromide and (b) hydrogen peroxide; (3)(c) chlorine, in the presence of a catalytic amount of iodine and/or hydr

Abstract: This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, their use in treating human or animal disorders. The compounds of the invention are useful as modulators of the interaction between the receptor for advanced glycated end products (RAGE) and its ligands, such as advanced glycated end products (AGEs), S100/calgranulin/EN-RAGE, &bgr;-amyloid and amphoterin, and for the management, treatment, control, or as an adjunct treatment for diseases in humans caused by RAGE. Such diseases or disease states include acute and chronic inflammation, the development of diabetic late complications such as increased vascular permeability, nephropathy, atherosclerosis, and retinopathy, the development of Alzheimer's disease, erectile dysfunction, and tumor invasion and metastasis.

Abstract: A liquid crystalline sulfur compound exhibiting high anisotropic factor of dipolemoment is provided. A terphenyl skeleton sulfur compound expressed by the general formula (I) is provided. A compound is preferred wherein, in the general formula (I), m is 1, n is 5 to 18, and R3 is an alkyl group wherein the number of carbon atoms is n or fewer than n. A method of synthesisng the terphenyl skeleton sulfur compound wherein, after implementing the synthesizing processes for a methoxy terphenyl derivative, a hydroxy terphenyl derivative, and terphenyl alkyloxy bromide derivative, that bromide derivative and thiourea are caused to react, etc. A self-assembled monolayer made using the terphenyl skeleton sulfur compound noted above is also provided.

Abstract: The invention relates to a process for preparing a 2-(thiosubstituted)-4-haloacetophenone such as those of formula (I), which comprises reacting a 2,4-dihaloacetophenone with a thiolating agent under substantially anhydrous conditions. In formula (I), R.sup.1 and R.sup.2 have the meanings given in the description and R.sup.3 is halogen. The compounds prepared are useful as intermediates in the preparation of herbicidally active compounds.

Abstract: Disclosed is a method of making a substituted diphenyldisulfide from a substituted thiophenol. A two phase reaction mixture is prepared which comprises a substituted thiophenol having the general formula ##STR1## hydrogen peroxide, water, an organic solvent, a basic salt that will give a pH between about 7 and about 10, and an optional flocculating agent. In the formula, R is selected from the group consisting of halogen, alkyl from C.sub.1 to C.sub.6, alkoxy from C.sub.1 to C.sub.6, or nitro. After the exothermic reaction is complete, the reaction mixture is cooled to crystallize the substituted diphenyldisulfide product. The symmetrical product precipitates preferentially over the unsymmetrical product, thereby enhancing the purity of the product over the purity of the starting material. Optionally, the organic solvent and the aqueous phase are recycled.

Abstract: A process for preparing a stabilized and deodorized organic polysulfide compound is provided which comprises contacting a crude polysulfide, in the presence of a solvent, optionally further in the presence of a basic compound, with a metal salt of an inorganic acid or a metal salt of an organic acid under conditions sufficient to produce the stabilized and deodorized polysulfide.

Abstract: A process for the purification of a perfluorochemical composition comprises continuously mixing the perfluorochemical composition, comprising a liquid mixture of inert perfluorochemicals (e.g., perfluoroalkanes, perfluoroethers, perfluoroaminoethers, or perfluoroalkyl tertiary amines) and isomeric fluorohydrochemicals, with a stabilization composition comprising water-miscible alkanol and an aqueous solution of base (such as potassium hydroxide) made by dissolving the base in an amount of water sufficient to dissolve or disperse the fluoride salt by-products of the subsequent reaction of the base with the fluorohydrochemicals to form fluoroolefins, the amount of the alkanol in the stabilization composition being in stoichiometric excess of the amount needed to completely convert the fluoroolefins to alkoxyvinyl ethers. The process can be utilized to purify the product mixtures resulting from fluorination methods such as direct fluorination or ECF.

Abstract: This invention provides 1) novel reactive fluorinated compounds derived from a specified class of telomers or cotelomers of fluoroolefins; and 2) stable products and stable polymers thereof obtained by reaction or polycondensation of the novel reactive fluorinated compounds with specified classes of hydrogenated aliphatic, alicyclic, aromatic reactive compounds, telechelic oligomers and block polymers wherein said stable products and polymers contain hetero atoms such as oxygen, sulfur or nitrogen and are characterized by high thermal and chemical resistance.

Abstract: Disulfides of the general formulaX.sup.1 --(CH.sub.2).sub.n --S--S--(CH.sub.2).sub.n --X.sup.2where X.sup.1 and X.sup.2 are identical to one another and are each --Br, --N-phthalimide, --NH.sub.2, --OOC--(CH.sub.2).sub.3 --COOH, --OSO.sub.2 --CH.sub.3, --NH--(CH.sub.2).sub.2 --NH.sub.2, --SO.sub.3 H or --SO.sub.3.sup.- M.sup.+ in which M.sup.+ is an alkali metal ion and n is from 11 to 25, or X.sup.1 is --OH and X.sup.2 is --Br or X.sup.1 and X.sup.2 are each --COO--CH.sub.2 --CH.sub.3 and n is from 10 to 25, are suitable for the production of monomolecular layers on noble metal substrates and for the production of multimolecular layers.

Abstract: The invention relates to benzocyclobutene capped benzotrifluoride based fluoroaryl ether compounds which are useful in preparing semi-permeable membranes, and films and coatings useful in electronic applications.

Abstract: The chiral smetic liquid-crystalline compounds of the general formula (I)M.sub.1.sup.* --B--M.sub.2.sup.* (I)solidify on cooling from the liquid-crystalline phase in glassy form, as a result of which they are suitable for materials for displaying and storing information. Such materials may be used in electro-optic data stores or display components which are based on the ferroelectric or electroclinic switching effect in a chiral or chirally doped, smetic liquid-crystalline phase.In the general formula, M.sub.1.sup.*, M.sub.2.sup.* stand for chiral smetogenic groups and --B-- is, as bridging link, a typical bivalent group.

Abstract: Polychlorinated polyphenyl materials are reacted with sulfur in the presence of an effective amount of a sulfur chloride compound to result in a product having a lowered residue of chlorinated polyphenyl as compared to a reaction practiced without the use of the compound.

Abstract: Organic sulfoxides having a latent allyl group bound to the sulfur are enzyme inhibitors of the suicide or K.sub.cat type.

Abstract: Organic sulfoxides having a latent allyl group bound to the sulfur are enzyme inhibitors of the suicide or K.sub.cat type.

Abstract: Organic sulfoxides having a latent allyl group bound to the sulfur are enzyme inhibitors of the suicide or K.sub.cat type.

Abstract: The new compounds, O,O dialkyl S-(2,3,4 trihalo) butyl phosphorothioates, are prepared by reacting 2,3,4 trihalo-butyl sulfenyl chloride with O,O dialkyl hydrogen phosphites, or other salts. The compounds of this invention have pesticidal activity, especially insecticidal and nematocidal activity.

Abstract: A method of preparing bis(trifluoromethyl) disulfide, which comprises contacting, in the gaseous state, 2,2,4,4-tetrakis(trifluoromethyl)-1,3-dithietane with activated carbon catalyst at elevated temperature is disclosed.