Two Benzene Rings Bonded Directly To The Same Carbonyl (i.e., Benzophenones) Patents (Class 568/332)
  • Patent number: 4801616
    Abstract: This invention provides certain diphenylmethane derivatives, their pharmaceutical formulations, and their use in treating inflammation and arthritis in mammals.
    Type: Grant
    Filed: March 25, 1986
    Date of Patent: January 31, 1989
    Assignee: Eli Lilly and Company
    Inventor: D. Mark Gapinski
  • Patent number: 4792635
    Abstract: Symmetric benzophenones substituted by groups containing fluorine are prepared by reacting aromatic compounds substituted by groups containing fluorine with formaldehyde and/or a formaldehyde derivative, with the addition of hydrogen fluoride, fluorosulphonic acid and/or sulphuric acid, to give the corresponding diphenylmethanes and oxidizing these. The symmetric benzophenones substituted by groups containing fluorine are used for the preparation of polyether ketones by reacting them with diols. New symmetric benzophenones substituted by groups containing fluorine are also disclosed.
    Type: Grant
    Filed: March 19, 1985
    Date of Patent: December 20, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Albrecht Marhold, Erich Klauke, Ernst Kysela
  • Patent number: 4772714
    Abstract: Disclosed is a process for the preparation of alpha-aryl and alpha-heteroaryl ketones useful as intermediates in the synthesis of various pharmaceutical and agricultural chemicals, which process operates according to the following reaction scheme: ##STR1##
    Type: Grant
    Filed: July 7, 1986
    Date of Patent: September 20, 1988
    Assignee: Agency of Industrial Science & Technology
    Inventors: Masato Tanaka, Toshiyasu Sakakura
  • Patent number: 4724267
    Abstract: Bis(haloacylaromatic) compounds have been made by a new process in which monohaloacylated aromatic compounds have been reacted by a coupling reaction. These bis(haloacylaromatic) compounds can be employed as monomers in the preparation of polyesters and polyamides which have easy processability. The monohaloacylated compound is coupled by reacting two moles of the monomer with a carbon or sulfur compound containing at least two halogen atoms in the presence of a Friedel-Crafts catalyst.
    Type: Grant
    Filed: May 23, 1986
    Date of Patent: February 9, 1988
    Assignee: The Dow Chemical Company
    Inventors: George M. St. George, Marlin E. Walters
  • Patent number: 4670581
    Abstract: New biphenyl compounds and a process for producing them are provided. These new compounds have an acyloxy group in the 2- or 4-position of the biphenyl and an acyl hydroxyalkyl, hydroxyalkenyl or vinyl group in the 4'-position of the biphenyl or, alternatively a hydroxyl group in the 2- or 4-position of the biphenyl and an acyl, hydroxyalkyl, hydroxyalkenyl or vinyl group in the 4'-position of the biphenyl. These compounds can be produced easily from 2- or 4-acyloxybiphenyl compounds.
    Type: Grant
    Filed: January 10, 1984
    Date of Patent: June 2, 1987
    Assignee: Sugai Chemical Industry Co., Ltd.
    Inventor: Teiichi Tanigaki
  • Patent number: 4622066
    Abstract: A fluorine-containing benzophenone derivative of the formula: ##STR1## wherein R.sup.1 is a group of the formula: --OM (in which M is hydrogen or alkali metal), lower alkoxy, lower acyloxy, a group of the formula: ##STR2## (in which R.sup.3 and R.sup.4 are same or different and hydrogen or lower alkyl) or a group of the formula: --OCH.sub.2 COOR.sup.5 (in which R.sup.5 is hydrogen, lower alkyl or alkali metal); R.sup.2 is halogen, nitro, chlorosulfonyl, sulfo, trifluoromethyl or a group of the formula: --SCF.sub.2 H; and m and n are each an integer of 1 to 4 provided that the sum of m and n is not more than 5 having selective herbicidal activities on grasses and crops.
    Type: Grant
    Filed: January 10, 1984
    Date of Patent: November 11, 1986
    Assignee: Daikin Kogyo Co., Ltd.
    Inventors: Katsuhiko Kitahara, Tetsuya Masutani, Takashi Yamaoka, Tetsuo Kitahaba, Takasi Nisioka, Yasuo Itami
  • Patent number: 4612322
    Abstract: A compound of the formula: ##STR1## (wherein Az is imidazolyl or triazolyl;R is C.sub.1 -C.sub.5 alkyl or phenyl optionally substituted by 1 to 3 members selected from halogen, C.sub.1 -C.sub.5 alkyl, and C.sub.1 -C.sub.5 alkoxy;X.sup.1 and X.sup.2 each is hydrogen, halogen, C.sub.1 -C.sub.5 alkyl, or C.sub.1 -C.sub.5 alkoxy;Y is C.dbd.O, C.dbd.S, S.dbd.O, or R.sup.1 --C--R.sup.2 ; andR.sup.1 and R.sup.2 each is hydrogen, C.sub.1 -C.sub.3 alkyl or, taken together may form C.sub.4 -C.sub.6 alkylene)or its acid addition salt being useful as an antimycotic agent is prepared by reacting a corresponding diol with a cyclizing agent.
    Type: Grant
    Filed: July 20, 1984
    Date of Patent: September 16, 1986
    Assignee: Shionogi & Co., Ltd.
    Inventors: Masaru Ogata, Hiroshi Matsumoto, Shiro Kida, Katsuya Tawara
  • Patent number: 4609668
    Abstract: The invention provides novel .alpha.-(ethynyl substituted phenyl)-.alpha.-hydrocarbyl-1H-azole-ethanols wherein the azole group is 1,2,4-triazol-1-yl or imidazol-1-yl, the ethynyl group is unsubstituted or substituted and the phenyl group may bear an additional substituent and ethers thereof, which are useful as fungicides.
    Type: Grant
    Filed: August 24, 1984
    Date of Patent: September 2, 1986
    Assignee: Sandoz Ltd.
    Inventors: Fritz Schaub, Rupert Schneider
  • Patent number: 4602097
    Abstract: Photoinitiators of the formulaG--O--(CH.sub.2 CH.sub.2 O).sub.n --CH.sub.2 --CH.sub.2 --O--Qwherein G is a photoinitiator moiety, R is hydrogen or lower alkyl, n has a value of at least 10, and Q is G or a lower alkyl are soluble in water and common organic solvents and are useful in polymerization systems employed in coatings used in screen printing.
    Type: Grant
    Filed: June 11, 1984
    Date of Patent: July 22, 1986
    Assignee: Ulano Corporation
    Inventor: John R. Curtis
  • Patent number: 4554360
    Abstract: Provided is a process for converting an aromatic compound to prepare an iodoarene, Ar--I, and an aryl compound which is a compound wherein an unsaturated compound is bonded directly to an aryl group, Ar, which process comprises reacting a diaryliodonium salt represented by general formula (I)[Ar--I.sup..sym. --Ar]X.sup..crclbar. (I)wherein Ar is an aryl group which may be substituted and two Ar's are identical and X.sup..crclbar. is a counter ion inert to the reaction with the unsaturated compound in a solvent in the presence of a transition metal catalyst and a base or a reducing metal, said reaction being carried out at a temperature not higher than 80.degree. C. and/or by using at least one of the base, the reducing metal and the unsaturated compound in an amount not more than 1.
    Type: Grant
    Filed: March 29, 1984
    Date of Patent: November 19, 1985
    Assignee: Nippon Petrochemicals Company, Limited
    Inventors: Yasuo Yamazaki, Takehiko Suzuki, Isoo Shimizu, Yasuo Matsumura
  • Patent number: 4529490
    Abstract: Aryliodonium salts resulting from the condensation of aryliodosotosylates and aryl ketones are provided which are used as photoinitiators to effect deep section UV cures. Deep section photopolymerizable organic materials are also provided which can be used as encapsulating agents to encapsulate a wide variety of electronic components.
    Type: Grant
    Filed: May 23, 1983
    Date of Patent: July 16, 1985
    Assignee: General Electric Company
    Inventors: James V. Crivello, Julia L. Lee
  • Patent number: 4499013
    Abstract: Certain fatty acids, esters and alcohol derivatives useful as electrical tree and water tree resistant compounds in polymer compositions are disclosed.
    Type: Grant
    Filed: August 17, 1983
    Date of Patent: February 12, 1985
    Assignee: National Distillers and Chemical Corporation
    Inventors: Anthony Barlow, Irwin S. Schlossman, Robert E. Borgerding
  • Patent number: 4439590
    Abstract: Novel poly-aromatic ethynyl-terminated enyne compounds of the formula: ##STR1## are provided together with a method of production thereof, wherein R.sub.1 is a strong electron withdrawing moiety and n is equal to or greater than 1.
    Type: Grant
    Filed: April 19, 1982
    Date of Patent: March 27, 1984
    Assignee: Celanese Corporation
    Inventor: Harry T. Hanson
  • Patent number: 4426536
    Abstract: Esters of phenylacetic acids are prepared in a single step by hydrolysis of 2,2,2-trichloro-1-phenylethanes in inorganic basic media.
    Type: Grant
    Filed: June 14, 1982
    Date of Patent: January 17, 1984
    Assignee: Eli Lilly and Company
    Inventor: Roger L. Robey
  • Patent number: 4393079
    Abstract: Anti-inflammatory compositions are prepared which comprise a therapeutically effective amount of a compound of the formula ##STR1## wherein X is CO or CHOH; Y is CO; the dotted line represents a double bond which is present or absent; R.sub.1 is hydrogen or methyl; R.sub.2 is hydrogen, fluorine, chlorine, bromine, methyl, trifluoromethyl, methoxyl, hydroxyl, acetoxyl, nitro or amino; R.sub.3 is alkyl of 3 to 8 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, alkenyl of 3 to 8 carbon atoms, cycloalkenyl of 5 to 8 carbon atoms or phenyl unsubstituted or substituted by 1 or 2 substituents selected from the group consisting of fluorine, chlorine, bromine, methyl, ethyl, methoxyl, ethoxyl, benzyloyl, hydroxyl, acetoxyl, trifluoromethyl, nitro, amino, acetyl, methylthiol, methylsulphonyl, methylamino and dimethylamino. Compounds of formula I above are also novel.
    Type: Grant
    Filed: December 15, 1976
    Date of Patent: July 12, 1983
    Assignee: Beecham Group Limited
    Inventors: William G. Cole, Alexander C. Goudie, Carl J. Rose
  • Patent number: 4374984
    Abstract: Compounds of the formula ##STR1## wherein the substituents A, Z, R.sup.1, R.sup.2, R.sup.3, R.sup.4, X, n and m are defined hereinbeloware effective photoinitiators, especially for the photopolymerization of ethylenically unsaturated compounds and for the curing of printing inks.
    Type: Grant
    Filed: March 4, 1981
    Date of Patent: February 22, 1983
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Jurgen Eichler, Claus Herz, Karl-Heinz Neisius, Gregor Wehner
  • Patent number: 4374291
    Abstract: Bis(ethynylphenyl) compounds are prepared by an improved synthesis process which increases yield and is suitable for large scale synthesis operations. Aromatic dianilines are diazotized to form aromatic halides that are subsequently coupled with an end-protecting group having acetylenic moieties. The end-protecting groups are subsequently removed leaving the desired diethynyl derivative in quantitative yields.
    Type: Grant
    Filed: November 6, 1981
    Date of Patent: February 15, 1983
    Assignee: Hughes Aircraft Company
    Inventor: Kreisler S. Y. Lau
  • Patent number: 4329507
    Abstract: New substituted aryl ethylenes are disclosed which are produced by dehydration of the corresponding .alpha.- or .beta.-(substituted aryl)ethyl alcohols or by dehydrohalogenation of the corresponding .alpha.- or .beta.-(substituted aryl)ethyl halides.
    Type: Grant
    Filed: January 14, 1980
    Date of Patent: May 11, 1982
    Assignee: Mitsubishi Petrochemical Co., Ltd.
    Inventors: Makoto Takeda, Masayuki Uchide, Hiroshi Iwane
  • Patent number: 4322346
    Abstract: New 5H-2,3-benzodiazepine derivatives of the formula ##STR1## wherein R is phenyl having a trifluoromethyl or halogen substituent,R.sup.1 is methyl,R.sup.2 is hydrogen,R.sup.3 is methoxy and R.sup.4 is methoxy, and the pharmaceutically acceptable acid addition salts thereof, are potent tranquilizers.
    Type: Grant
    Filed: September 26, 1980
    Date of Patent: March 30, 1982
    Inventors: Jeno Korosi, Tibor Lang, Jozsef Szekely, Ferenc Andrasi, Gabor Zolyomi, Jozsef Borsi, Katalin Goldschmidt nee Horvath, Tamas Hamori, Gabriella Szabo nee Czibula, Zsuzsanna Meszaros nee Dunai-Kovacs, Erzsebet Miglecz
  • Patent number: 4318854
    Abstract: Compounds of the formula ##STR1## wherein X and Y are selected from the group consisting of hydrogen, halogen and trifluoromethyl, are disclosed.The compounds are useful as intermediates in the production of 2-benzazepines, compounds of pharmacological activity.Also disclosed are other intermediates and processes for their production.
    Type: Grant
    Filed: May 16, 1980
    Date of Patent: March 9, 1982
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Eugene J. Trybulski
  • Patent number: 4243589
    Abstract: There is presented triazolobenzazepines of the formula ##STR1## wherein R.sub.1 is hydrogen or lower alkyl and X and Y are hydrogen or halogenand the pharmaceutically acceptable salts thereof.Also disclosed are novel processes and intermediates leading to the triazolobenzazepines.The triazolobenzazepines are useful compounds having anxiolytic, sedative, muscle relaxant and anticonvulsant activity.
    Type: Grant
    Filed: November 30, 1979
    Date of Patent: January 6, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Rodney I. Fryer, Eugene J. Trybulski, Armin Walser
  • Patent number: 4205184
    Abstract: A method for processing a tar which is formed during the oxidation of an alkyl-benzene compound and which contains substituted or unsubstituted benzyl benzoate, which method comprises the steps of subjecting the tar to either hydrolysis or ammonolysis and then extracting the reaction mixture which is formed from the hydrolysis or ammonolysis. The extracting agent is organic and causes the reaction mixture to separate into liquid phases. The liquid phases are then separated for further processing.
    Type: Grant
    Filed: December 27, 1977
    Date of Patent: May 27, 1980
    Assignee: Stamicarbon, B.V.
    Inventor: Cornelis Jongsma