Abstract: In part, the present invention is directed to coordination complexes comprising a therapeutic agent. In one aspect, the subject compositions comprise a platinum metal center and a covalently attached therapeutic agent.
Type:
Grant
Filed:
January 12, 2004
Date of Patent:
November 21, 2006
Assignee:
Massachusetts Institute of Technology
Inventors:
Stephen J. Lippard, Carmen M. Barnes, Ariel Haskel, Katie R. Barnes
Abstract: The present invention is directed to a process for synthesizing A-nor and A-nor-18-homo-steroids. The invention is concerned with providing a total synthesis for the compounds called Dinordin and 18-homo-Dinordin. The preparation of other compounds will also be evident.