N-containing Patents (Class 585/933)
  • Solution phase biopolymer synthesis
    Patent number: 7094943
    Abstract: Multifunctional liquid phase carriers (LPCs) and methods of using LPCs for the preparation of biopolymers are provided. The LPCs are highly symmetrical compounds that possess more than two points of attachment for biopolymer synthesis. The LPCs have the formula Sp(X1)n, where Sp is a highly symmetrical moiety such that all X1 groups are equivalent. X1 is a functional group that is suitable for biopolymer synthesis, including OH, SH, NH2, COOH and the like. Biopolymers that may be produced using the methods provided include oligonucleotides, peptides, protein nucleic acids (PNAs) and oligosaccharides. Analogs of the biopolymers may also be prepared using the methods.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: August 22, 2006
    Inventors: Hubert Köster, Ralf Wörl
  • Solution phase biopolymer synthesis
    Patent number: 7038103
    Abstract: Multifunctional liquid phase carriers (LPCs) and methods of using LPCs for the preparation of biopolymers are provided. The LPCs are highly symmetrical compounds that possess more than two points of attachment for biopolymer synthesis. The LPCs have the formula Sp(X1)n, where Sp is a highly symmetrical moiety such that all X1 groups are equivalent. X1 is a functional group that is suitable for biopolymer synthesis, including OH, SH, NH2, COOH and the like. Biopolymers that may be produced using the methods provided include oligonucleotides, peptides, protein nucleic acids (PNAs) and oligosaccharides. Analogs of the biopolymers may also be prepared using the methods.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: May 2, 2006
    Assignee: Hubert Koster
    Inventors: Hubert Köster, Ralf Wörl