Abstract: Intestinal devices and methods for facilitating weight loss. In at least one embodiment of a method of patient treatment of the present disclosure, the method comprises the step of positioning a device, that is configured to reduce or limit localized intestinal distension, around a portion of an intestine of a patient.

Abstract: A device for performing surgery on a patient includes: a mesh patch comprising a top surface and a bottom surface; and a removable cover positioned adjacent to and in facing engagement with the bottom surface of the mesh patch. The bottom surface has a plurality of hooks positioned thereon. The cover is removed from the mesh patch as the mesh patch is positioned at a surgical site such that the hooks on the bottom of the mesh patch grip surrounding tissue of a patient and secure the mesh patch to surrounding tissue of the surgical site. A method for performing a surgery using such a device is also provided.

Abstract: A tool includes a brace and a hook. The brace includes two posts extending from a base portion. The two posts include a first post that is spaced a distance apart from a second post, with the first post disposed in a first plane and the second post disposed in a second plane that is not the same as the first plane. A side of the base portion opposite from the first post and opposite from the second post includes a recess formed in the base portion. The hook is connected to a handle. The hook has a first section attached to the handle, a second section that is curved to have a J-hook curvature configured for accessing an obturator foramen of the patient, and a third section including a tip. The tip of the hook is removably insertable into the recess formed in the base portion.

Abstract: An artificial urinary sphincter (AUS) system includes a cuff, a pump, and a single tube that provides the system with an inflatable storage compartment. The single tube is connected between the cuff and the pump and includes a first lumen communicating between the cuff and the pump and a separate second lumen communicating between the cuff and the pump. The cuff is inflatable with a cuff volume of liquid that is sized to selectively close the urethra for treatment of urinary incontinence. The pump is operable to move the cuff volume of liquid out of the cuff to provide the cuff with a deflated state that allows the urethra to open and pass urine. The second lumen has a storage compartment sized to retain the cuff volume of liquid.

Abstract: An implantable penile prosthesis having an inflatable cylinder with at least one piezoelectric pump for transferring fluid between an integrated reservoir and pressure chamber within the inflatable cylinder. The piezoelectric pump includes an actuator powered by an inductor coil integrated into the inflatable cylinder allowing for wireless control of the inflation and deflation of the inflatable cylinder. An external control system having a corresponding inductive coil can be used to supply a magnetic field for creating a current in the inductor coil integrated into the inflatable cylinder.

Abstract: A fastening system for fastening tissue that comprises a cartridge and an implant is disclosed. The cartridge comprises a cartridge body comprising removable fasteners. The implant comprises a first portion comprising a first absorbable polymer comprising a first compactness of first fibers and a first medicament releasably stored in the first compactness of the first fibers of the first portion. The implant further comprises a second portion comprising a second absorbable polymer comprising a second compactness of second fibers, wherein the second compactness is different than the first compactness. The second absorbable polymer is different than the first absorbable polymer. The implant further comprises a second medicament releasably stored in the second compactness of the second fibers of the second portion. The second medicament is different than the first medicament. The release of the second medicament and the release of the first medicament co-operatively produce a healing result.

Abstract: A manually-actuated, constant reduced-pressure apparatus for use with a reduced-pressure system for treating tissue at a tissue site includes a flexible, collapsible member that is operable to move between a compressed position and an extended position. The collapsible member may be disposed between a carrier member and a slider member that move between a compressed position and an extended position. The carrier member and slider member are urged away from each other by a constant-force biasing member, e.g., a constant force coil spring. As the apparatus moves from the compressed position to the extended position, a constant reduced-pressure is generated and delivered to a reduced-pressure port. Methods of manufacturing a manually-actuated, constant reduced-pressure apparatus and methods of treating a tissue site are also provided.

Abstract: A wire stent assembly that has a first ring defining one end of the stent assembly, a second ring defining the second end of the stent assembly. Each ring is formed of wire. The wire of each ring also has a second section that extends parallel to the longitudinal axis of the wire stent assembly and perpendicular to the rings. Each of the rings has a loop that is parallel to the longitudinal axis and parallel to the rings. The stent assembly may form the support structure for a stent graft.

Abstract: Described are various embodiments of surgical procedures, systems, implants, devices, tools, and methods, useful for treating pelvic conditions in a male or female, the pelvic conditions including incontinence (various forms such as fecal incontinence, stress urinary incontinence, urge incontinence, mixed incontinence, etc.), vaginal prolapse (including various forms such as enterocele, cystocele, rectocele, apical or vault prolapse, uterine descent, etc.), and other conditions caused by muscle and ligament weakness, the devices and tools including devices and tools for anchoring an implant to supportive tissue and adjusting the implant.

Abstract: An incontinence treatment system includes a urethral support extending between a first end and a second end, a first connector attached to the first end of the urethral support and a second connector attached to the second end of the urethral support, and an energy source. At least one of the first connector and the second connector is a cross-linked polymer connector having a glass transition temperature between 40-70 degrees Celsius. In this regard, the cross-linked polymer connector is stretched to provide a stretched cross-linked polymer connector having a product length. The energy source is adapted to provide energy from an extracorporeal location through intact skin to shorten the stretched cross-linked polymer connector to an implant length that is less than the product length.

Abstract: An implantable medical device and surgical instrument for use during a procedure for treatment of vaginal vault prolapse. The invention also includes an instrument which allows the pieces of the suspension material to be attached to each other and enables the appropriate suspension of the vaginal apex from the anterior part of the sacrum. The device and method permit the performance of a sacrocolpopexy by accessing the sacrum and vaginal tissues via the vaginal orifice, thus avoiding the abdominal cavity completely.

Abstract: A method of treating prolapse of a vagina is provided by placing a reinforcing implant inside of the vagina. The method includes inserting a porous sheet of material inside of the vagina through a natural vaginal opening of the patient. The porous sheet of material is an implantable support that is adapted to integrate with tissue inside of the vagina to reinforce and support at least an apical portion of the vagina. The method includes maintaining the apical portion of the vagina in an anatomically natural position by supporting the porous sheet of material inside of the vagina relative to one of a sacrum and a ligament of the patient.

Abstract: An apparatus for placing a cardiac support device (CSD) on a heart. The apparatus includes a body, a deployment mechanism on the body for supporting the CSD in an open position for placement on the heart, and a release mechanism coupled to the deployment mechanism for releasably mounting the CSD to the deployment mechanism. The release mechanism includes a release element for releasably engaging the CSD, and a release actuator coupled to the release element for actuating the release element to release the CSD.

Abstract: A snare for retrieving foreign objects within the body of a patient including a hollow elongate tubular member comprising an inner surface and an outer surface and a lumen defined by the inner surface, a proximal end and a distal end, the hollow elongate tubular member forms a loop at the distal end, the loop having an open position and a closed position, the loop comprising at least one opening and a wire slidably disposed in the lumen of the elongate tubular member, the wire comprising at least one engaging member for engaging tissue, the at least one engaging member extends through the at least one opening in the hollow elongate tubular member when the wire is in a first position and the at least one engaging member retracts into the lumen of the elongate tubular member when the wire is moved to a second position.

Abstract: A hernia repair prosthesis comprises a segmented frame forming a closed loop where a first segment comprises a helical hollow tube and a second segment comprises a solid strand. Both segments are preferably a metal exhibiting shape memory properties and the two segments are assembled with end portions of the second segment inserted into the lumen at opposed end portions of the first segment with a clearance fit. At manufacture, a covering layer of a bio-absorbable polymer on the end portions of the second strand is sufficiently sized to create a temporary interference fit between the two segments to inhibit relative movement between them. The ability of the intercoupled segment to move relative to one another is restored upon degradation of the polymer due to exposure to body fluids following implantation of the prostheses. A prosthetic fabric is attached to the segmented frame.

Abstract: A tissue anchor system includes a support material, a suture engaged with the support material, an anchor, and an introducer. The anchor has a body, a fin extending from the body in a first direction with an eyelet formed in the fin, a pair of radial barrels extending from the body in a radial direction perpendicular to the first direction, and a gripping tab removably attached to the fin. The suture is engaged with the eyelet of the fin. The introducer has a cannula with a bore sized to receive the body of the anchor and a slot formed in a wall of the cannula. The slot is sized to receive the fin of the anchor, and an ejection mechanism provided to eject the anchor out of the cannula.

Abstract: Methods and devices are disclosed for breast reconstruction surgery. An implantable fixation device is attached to pectoralis muscle tissue and a tissue graft that forms a sling for supporting a tissue expander or permanent breast implant. The implantable fixation device provides flap stabilization of overlying skin and reduces breast reconstruction complications such as seroma formation.

Abstract: Feedback systems and methods enhance obstructive and other obesity treatments by presenting feedback regarding patients' actual eating. An ingestion restricting implant body can be deployed along the gastrointestinal tract. In some embodiments, ingestion alters the implant body, which, in turn, generates signals. The generated signals can be used to inhibit unhealthy ingestion by the patient. In other embodiments, the implant body can be altered by signals so as to selectable change the restriction imposed on the gastrointestinal tract, optionally in response to ingestion events, an eating schedule, or the like. The implant body may comprise a gastric band. Sensor signals may be processed to identify ingestion and/or characterize ingestion material, and the results may be displayed on a screen for a patient or coach to view.

Abstract: A system and method for regenerating damaged or necrosed tissue. Negative or vacuum pressure is applied to a surface of the damaged tissue to stimulate the revascularization of the area and/or increased blood flow to the area, which encourages the regeneration of the damaged tissue. A negative pressure device is provided that is capable of providing a sequenced vacuum treatment regimen to damaged tissue.

Abstract: A colpotransilluminator is provided for arrangement on a uterus manipulator, wherein the colpotransilluminator is designed in a sleeve-shaped manner of an elastic material. The colpotransilluminator at a distal first axial end forms a portio receiver and at a proximal second end forms a vaginal seal. In a central region between the first and the second axial ends, the colpotransilluminator is designed in a waist-shaped manner and includes axially extending stretch folds in the region of the waist. A uterus manipulator is also provided with such a colpotransilluminator.

Abstract: In one embodiment, a medical device includes a first elongate portion and a second elongate portion. The first elongate portion defines a loop and has a first end portion and a second end portion. The first end portion is configured to be removably coupled to an implant. The second elongate portion has a first end portion and a second end portion. The first end portion of the second elongate portion is coupled to the first elongate portion. The second end portion of the second elongate portion is configured to be removably coupled to an insertion tool.

Abstract: Absorbable implants for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and/or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the ingrowth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy/breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof.

Abstract: An intravascularly-deliverable electrode assembly can be used to provide electrostimulation. The electrode assembly can include an electrostimulation circuit located in a housing, two or more elongate members coupled to the housing and configured to anchor the housing to a heart, the two or more elongate members including two or more electrodes electrically coupled to the electrostimulation circuit and controllably addressable by the electrostimulation circuit for delivery of an electrostimulation to the heart. The two or more elongate members can be sized and shaped for intravascular delivery to the heart in a first configuration, and in response to a user actuation, the two or more elongate members can move to a second configuration that is expanded relative to the first configuration to securely anchor the intravascularly-deliverable electrode assembly to the heart. Circuitry within the electrode assembly can coordinate electrostimulation, such as for delivery to sites near each electrode.

Abstract: Methods and apparatus for treating disc herniation provide a conformable device which assumes a first shape associated with insertion and a second shape or expanded shape to occlude the defect which typically follows partial discectomy. The device may take different forms according to the invention, including patches size to cover the defect or plugs adapted to fill the defect. In a preferred embodiment, however, the device is a gel or other liquid or semi-liquid which solidifies to occlude the defect from within the body of the disc itself. In another preferred embodiment, a mesh screen is collapsed into an elongated form for the purposes of insertion, thereby minimizing the size of the requisite incision while avoiding delicate surrounding nerves.

Abstract: A specimen retrieval device is provided. The specimen retrieval device includes a housing that includes an outer shaft extending distally therefrom. An inner shaft is disposed within the outer shaft and includes a spring including two or more members. One or both of the members includes a support member interface member. A pouch is releasably couplable to the members and includes a cinch having a proximal end that is passable through the outer shaft for grasping by a user. The pouch includes a pair of openings that lead to a sleeve that is provided on the pouch. Each of the openings is configured to receive a respective one of the members so as to allow the support member interface member on the member(s) to engage a corresponding pocket on the pouch.

Abstract: A system for magnetically suspending tissue includes a grasper placement tool, a tissue grasper, a magnetic coupling element, and a tether which secures the magnetic coupling element to the tissue grasper. The grasper placement tool is used to simultaneously introduce both the tissue grasper and the magnetic coupling element to a body cavity. The grasper then releases the magnetic coupling element and engages a target tissue structure. The tissue grasper is then detached from the placement tool and a conventional laparoscopic or other grasper is used to engage the magnetic coupling element to an external magnet.

Abstract: The present invention discloses a medical assembly including an implant, a first sleeve, a second sleeve and an elongate member. The implant has a first portion, a second portion and a mid portion. The first portion of the implant is configured to be enclosed by the first sleeve and the second portion of the implant is configured to be enclosed by the second sleeve. The elongate member is configured to couple the implant with the first sleeve and the second sleeve and is configured to respectively extend from the first portion to the mid portion of the implant and past the mid portion such that the elongate member exits the implant through the mid portion and forms a loop near the mid portion.

Abstract: An implantable device includes a body member having a bottom side that is parallel to a top side; a pair of legs extending from the bottom side of the body member; and a pair of arms extending from the body member perpendicular to the pair of legs and a second arm extending from the body member perpendicular to the pair of legs.

Abstract: Disclosed are methods and devices for minimally invasive mastopexy, or other soft tissue suspension, which may be accomplished with our without augmentation.

Abstract: A surgical retrieval apparatus includes a tube assembly, a cartridge assembly, and a plunger assembly. The cartridge assembly is releasably engagable with the tube assembly and includes an end effector assembly disposed therein. The end effector assembly includes a specimen retrieval bag releasably coupled thereto at a distal end thereof and a first engagement member disposed at a proximal end thereof. The plunger assembly is configured for insertion through the tube assembly and into the cartridge assembly. The plunger assembly includes a second engagement member configured for releasably engaging the first engagement member. When the first and second engagement members are engaged with one another, the plunger assembly is movable between a more proximal position, wherein the end effector assembly and specimen retrieval bag are retracted within the cartridge assembly, and a more distal position, wherein the end effector assembly and specimen retrieval bag are deployed from the cartridge assembly.

Abstract: Disclosed are implants for pelvic floor repair and related uses, and devices, kits, and methods which can be used to deliver the implants. In certain embodiments, the devices are used to deliver extensions of a surgical implant to respective target tissue regions of the levator ani muscle and the sacrospinous ligament.

Abstract: An image processing apparatus includes an image acquisition unit that acquires image information representing a fluorescence observation image of a specimen stained with hematoxylin-eosin, a spectrum generation unit that generates a plurality of spectra each representing a wavelength distribution of fluorescence intensity in a plurality of pixels in the fluorescence observation image, a pixel extraction unit that extracts at least two pixel groups with a feature of a particular spectrum from the plurality of pixels, and an image generation unit that generates an image based on the extracted pixel groups.

Abstract: A medical device and method of delivery of the medical device within a patient's body are disclosed by the present invention. The medical device includes a first elongate member and a second elongate member. A first portion and a second portion of the second elongate member are configured to form a defined non-planar shape such that the first portion is a first arm of the defined non-planar shape and the second portion is a second arm of the defined non-planar shape.

Abstract: In one embodiment, an umbilicus support apparatus includes a base and an armature that extends from the base, the armature including a flexible arm having a proximal end and a distal end, the armature further including a support head attached to the distal end of the arm, the support head including umbilicus securing means for securing an umbilicus.

Abstract: Apparatus (10) is provided that includes an extra-vascular ring (12) and an endo vascular stent-graft (14). The ring (12) comprises a structural member (30), which is configured to assume an elongate hollow shape (32), which has first and second longitudinal ends (40, 42), and is suitable for placement at least partially around an aorta (20) so as to provide a generally cylindrical landing zone. The endovascular stent-graft (14) is suitable for endovascular placement inside the aorta (20) such that a portion of the stent-graft (14) is positioned against an internal wall of the aorta (20) at the landing zone provided by the structural member (30).

Abstract: An implant assembly for treating incontinence in a patient may include an implant and an elongated member. The implant may include a first arm, a second arm, and a central portion, the first and second arms extending from the central portion. The elongated member may extend along the first arm. The elongated member may include a tail portion at a first end portion of the elongated member, the tail portion having a planar portion, at least part of the tail portion extending beyond the central portion of the implant in a direction opposite from a direction that the first arm extends from the central portion of the implant, an envelope portion, the envelope portion defining a lumen through which the first arm extends, and a window portion comprising a single planar portion extending from the envelope portion.

Abstract: A pelvic organ prolapse treatment device includes an implantable support sized to support and treat a prolapsed organ of a patient, a suture, a knot separate from the suture, and a dilator. The implantable support includes an arm having a first portion connected to a body of the implantable support and an end portion extending away from the body of the implantable support. The end portion of the arm is folded to include a first fold and a second fold that combine to reduce a lateral dimension of a portion of the end portion of the arm. The suture extends away from the end portion of the arm. The knot is provided separately from the suture and is secured around the first fold and the second fold to capture both the end portion of the arm and the suture. The dilator is disposed over and connected to the knot.

Abstract: Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.

Abstract: In one embodiment, an implant is configured to be placed within a body of a patient. The implant includes a support member. The support member is configured to be placed adjacent a vaginal apex of a patient. The support member has a length sufficient to extend the length of the vaginal apex but not of a length sufficient to extend from the vaginal apex to a location between a vagina of the patient and a rectum of the patient. The implant also includes first and second arm members coupled to the support member. The arm members are configured to be coupled to bodily tissue of the patient to help secure the implant within the body of the patient.

Abstract: Apparatus, systems, and methods are described for closing the base of a left atrial appendage or other tissue structure. A tissue closure device comprises a pair of legs having compliant surfaces for engaging against opposite sides of the tissue structure. A plurality of axially spaced-apart tissue-penetrating fasteners are delivered from one leg to the other to pierce the intervening tissue and hold the closure device in place on the tissue structure.

Abstract: Systems for providing support to body tissue to alleviate incontinence are disclosed that comprise an elongated incontinence sling having a central support portion adapted to be positioned to support any one of the urethra or anus and first and second sling end portions extending from the central support portion through body tissue and a tension adjustment mechanism acting on or within one or both of the sling end portions. The sling tension adjustment mechanism comprises one or more of a sling tensioning suture or band, a tensioning device coupled to a suture or band free end, a tissue anchor coupled to one or more of a suture free end and a sling end, a mesh fold, a suture tube, and a sling sheath in various combinations.

Abstract: A method of retrieving a tissue specimen comprising inserting a surgical retrieval apparatus through an opening in a patient's skin, the surgical retrieval apparatus including a support member and a retrieval bag extending from the support member and having an opening to receive the tissue specimen. A net is introduced into the retrieval bag and placed over the tissue specimen. The net and retrieval bag are removed from the patient's body to remove the tissue specimen.

Abstract: Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.

Abstract: In a general aspect, a medical device includes a receiving arm configured to be coupled to at least a portion of an implant, and a clamping arm having a proximal end coupled to the receiving arm and having a track at a distal end of the clamping arm. The medical device also includes a sliding component including a needle and configured to slidably move along the track of the clamping arm.

Abstract: The invention relates to a reprogrammable shape change sheet, a method of shaping a surface and a reprogrammable injection molding machine. The sheet comprises a plurality of muscle elements capable of changing shape upon electric stimulation, the elements being arranged in an array to define a surface. According to the invention, the muscle elements comprise two muscle material layers capable of changing shape upon electric stimulation and a flexible wiring layer sandwiched between the muscle material layers, the wiring layer being electrically connected to said muscle material layers for delivering electric stimulation signals to the muscle material layers for changing the shape of the muscle elements and further the topology of the surface. The invention provides a new shape change sheet structure, which can be made thin, accurate and durable for various uses.

Abstract: An implantable medical device and a surgical instrument for using the device in a procedure for the treatment of vaginal vault prolapse are disclosed. In one form of the device, one attachment part attaches to the anterior and posterior parts of the vaginal apex, and the other attachment part attaches to anterior part of the sacrum. The two attachment parts are capable of being attached together during the procedure in a manner which permits appropriate adjustment of tension. The invention also includes an instrument which allows the pieces of the suspension material to be attached to each other and enables the appropriate suspension of the vaginal apex from the anterior part of the sacrum. In another form of the device, one attachment part attaches to the anterior part of the vaginal apex, another separate attachment part attaches to the posterior part of the vaginal apex, and another separate attachment part attaches to anterior part of the sacrum.

Abstract: Embodiments described include devices, systems, and methods for reducing the distance between two locations in tissue. An anchor may reside within the right ventricle in engagement with the septum. A tension member may extend from that anchor through the septum and an exterior wall of the left ventricle to a second anchor disposed along a surface of the heart. Perforating the exterior wall and the septum from an epicardial approach can provide control over the reshaping of the ventricular chamber. Guiding deployment of the implant from along the epicardial access path and another access path into and through the right ventricle provides control over movement of the anchor within the ventricle. The joined epicardial pathway and right atrial pathway allows the tension member to be advanced into the heart through the right atrium and pulled into engagement along the epicardial access path.

Abstract: A medical treatment device (200), for treating reflux from a stomach (201) to an esophagus (202) and for delivering a therapeutic agent to an inner surface of the esophagus (202), comprises a valve member (203), a lining member (204), and a support member (205). The valve member (203) is movable between a closed configuration and an open configuration, in which the valve member (203) facilitates passage of material between the esophagus (202) and the stomach (201). The valve member (203) is biased towards the closed configuration and gradually moves over a period of 4 to 10 secs from the open configuration to the closed configuration. The support member (205) supports the device (200) relative to the esophagus (202) and the stomach (201). The lining member (204) lines part of the inner surface of the esophagus (202) for delivery of a therapeutic agent to the esophagus (202).

Abstract: An apparatus including an elongated apparatus structure configured to fit around a body part of a user and an actuator configured to change shape of the elongated apparatus structure. The actuator is configured to change tightness of the elongated apparatus structure around the body part of the user based on an action the apparatus is performing.

Abstract: In one embodiment, an implant includes a body member and an extension member. The body member is formed of a first material and has a first side portion and a second side portion. The extension member is formed of a second material different than the first material. The extension member has a first arm portion, a second arm portion, and a mid-portion disposed between the first arm portion and the second arm portion. The mid-portion extends from the first side portion of the body member to the second side portion of the body member. The first arm portion extends from the first side portion of the body member along a first axis. The second arm portion extends from the second side portion of the body member along a second axis different than the first axis.