Light Conducting Fiber Inserted Into A Body Patents (Class 600/478)
  • Publication number: 20140180031
    Abstract: The present invention generally relates to devices that include multiple sensors for measuring different characteristics inside a vessel. For example, devices of the invention may have sensors for imaging the interior of a vessel while also detecting both pressure and/or detecting flow inside the vessel.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 26, 2014
    Applicant: VOLCANO CORPORATION
    Inventor: David Anderson
  • Publication number: 20140180134
    Abstract: The invention generally relates to balloon catheters for vascular intervention and particularly to devices for imaging from within a balloon. The invention provides a balloon catheter with an imaging device inside the balloon and capable of viewing a treatment site through a wall of the balloon. The device allows a physician to both view the affected site within the vessel and to inflate the balloon at the location that is in view, thus allowing the balloon to be deployed with good positioning and efficiency while minimizing a stiff length of the catheter to give it good maneuverability.
    Type: Application
    Filed: December 17, 2013
    Publication date: June 26, 2014
    Applicant: VOLCANO CORPORATION
    Inventor: Paul Hoseit
  • Patent number: 8761865
    Abstract: The invention provides a device 10 for analysis of tissue cells 12 in a living body, the device comprising a stylet 14, the stylet comprising a clad optical fiber senior 18 enveloped in a tubular jacket 20, wherein an unclad area 24 of the fiber and a jacket window 26 corresponding to the unclad area are proximate to the distal end 28 thereof, the optical fiber 18 being linked at a proximate end 30 to receive light from a light source 32, the device further including a light analyzer 34 for measuring qualities of output light at the depth at which the unclad area 24 is positioned in the body during use, an electronic data processor 36 being linked between the light analyzer 34 and a display 38 provided to show real-time data regarding any area 40 evidencing a change in optical properties of body tissues being successively examined.
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: June 24, 2014
    Inventor: Anatoly Babchenko
  • Publication number: 20140142436
    Abstract: In one aspect, the invention relates to one or more rotatable elements and one or more stationary element such that the elements are arranged along a common axis of rotation co-linear with or substantially parallel to an optical path. The optical path is a portion of a sample arm of an interferometer. Further, the rotatable and stationary elements are configured to couple electrical signals and optical signals between a data collection probe and an interface unit or other component of an imaging system. In one embodiment, the data collection probe is a combination ultrasound and OCT probe. In one aspect, the invention relates to a rotary joint in which the optical fiber and a fiber optic rotary joint lie in the center of one or more conductive elements of an electrical rotary joint which are annularly disposed around one or both of the optical fiber and optical rotary joint.
    Type: Application
    Filed: February 4, 2013
    Publication date: May 22, 2014
    Inventors: Christopher Hutchins, Michael Atlas, Alexander Ship
  • Publication number: 20140135630
    Abstract: An optical spectroscopic injection needle assembly. According to one embodiment, the assembly may include an injection needle, a light source, a spectrometer, a computer and an indicator. The injection needle, in turn, may include a hollow outer needle, a hollow inner needle, a pair of optical fibers, an inner catheter, an outer catheter, an inner hub and an outer hub. The proximal end of the outer needle may be fixedly mounted within the distal end of the inner catheter. The distal end of the inner hub may be fixedly mounted on the proximal end of the inner catheter, the proximal end of the inner hub being suited for connection to a syringe. The inner needle, as well as the distal ends of the optical fibers, may be positioned within the outer needle and may be held in place by an optical bonding material. The proximal ends of the optical fibers may extend from a side arm of the inner hub, one fiber may be coupled to the light source, the other fiber may be coupled to the spectrometer.
    Type: Application
    Filed: January 15, 2014
    Publication date: May 15, 2014
    Applicant: Boston Scientific Scimed, Inc.
    Inventor: Malka S. BERNDT
  • Patent number: 8725525
    Abstract: The present invention relates to an endoscope system including: a real time clock; an interface for receiving medical information output from a peripheral device; and a control unit that adjusts clock information added to the received medical information into clock information of the real time clock when the peripheral device adds the clock information to the medical information, and adds clock information of the real time clock at a time of receiving to the received medical information when the peripheral device does not add the clock information to the medical information. According to the invention, even the medical information obtained from the different devices can be reproduced with data from the respective devices synchronized by associating the clock information based on the identical real time clock therewith. Consequently, even after the surgical operation, the contents of treatment performed during the surgical operation can be accurately reproduced.
    Type: Grant
    Filed: April 13, 2005
    Date of Patent: May 13, 2014
    Assignee: Olympus Corporation
    Inventor: Masahide Yamaki
  • Patent number: 8725234
    Abstract: The present invention provides systems, devices, and methods employing fiber optic shape and position tracking. The systems, devices, and methods permit measurement of and continuous tracking of the shape and position of objects whose shape dynamically changes with time. Applications include tracking and monitoring of endoscopes for diagnostic and surgical procedures.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: May 13, 2014
    Assignees: Tufts University, The Governing Council of The University of Toronto, University Health Network
    Inventors: Caroline G. L. Cao, Peter Y. Wong, Lothar Lilge, Paul Milgram
  • Publication number: 20140121538
    Abstract: A needle is proposed including a cannula or hollow shaft with a multilumen insert inside. The insert comprises at least two lumen. Both the insert as well as the cannula have bevelled ends. In the insert substantially straight cleaved fibers are present that may be connected at the proximal end to a console. At least one of the distal fiber ends in the insert may protrude more than half the fiber diameter out of the insert. Furthermore, the bevel angle of the insert is different from the bevel angle of the cannula such that combination cannula and insert is such that the fiber ends do not protrude the bevel surface of the cannula.
    Type: Application
    Filed: June 13, 2012
    Publication date: May 1, 2014
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventors: Bernardus Hendrikus Wilhelmus Hendriks, Waltherus Cornelis Jozef Bierhoff, Gerhardus Wilhelmus Lucassen, Jeroen Jan Lambertus Horiks, Susanne Dorien Van Den Bergdams, Christian Reich, Stephan Voss, Axel Winkel, Rami Nachabe, Manfred Muller, Marjolein Van Der Voort
  • Publication number: 20140121537
    Abstract: A fiber optic force sensing assembly for detecting forces imparted at a distal end of a catheter assembly. The structural member may include segments adjacent each other in a serial arrangement, with gaps located between adjacent segments that are bridged by flexures. Fiber optics are coupled to the structural member. In one embodiment, each fiber optic has a distal end disposed adjacent one of the gaps and oriented for emission of light onto and for collection of light reflected from a segment adjacent the gap. The optical fibers cooperate with the deformable structure to provide a change in the intensity of the reflected light, or alternatively to provide a variable gap interferometer for sensing deformation of the structural member. In another embodiment, the gaps are bridged by fiber Bragg gratings that reflect light back through the fiber optic at central wavelengths that vary with the strain imposed on the grating.
    Type: Application
    Filed: October 28, 2013
    Publication date: May 1, 2014
    Inventors: Nicolas Aeby, Giovanni Leo
  • Publication number: 20140121536
    Abstract: Systems and methods are provided herein that generally involve measuring a prostate or other object. In some embodiments, a membrane can be sealed over a digit extension to form a closed volume. The closed volume can be inflated via an inflation tube, and a reference pattern can be disposed within the closed volume along with a measurement assembly. In use, a user can put on the glove, position the membrane in proximity to a rectal wall overlying a prostate, and inflate the membrane. As the user slides their finger across the rectal wall, optical fibers in the measurement assembly can move relative to a reference pattern, and a controller can sense light reflected through the fibers from the reference pattern. The controller can calculate or estimate various attributes of the prostate based on the reflected light, such as the palpable surface width or volume.
    Type: Application
    Filed: October 30, 2012
    Publication date: May 1, 2014
    Applicant: MedicalMetrix, Inc.
    Inventor: Christopher LaFarge
  • Publication number: 20140121535
    Abstract: Systems and methods are provided herein that generally involve measuring a prostate or other object. In some embodiments, a membrane can be sealed over a digit extension to form a closed volume. The closed volume can be inflated via an inflation tube, and a reference pattern can be disposed within the closed volume along with a measurement assembly. In use, a user can put on the glove, position the membrane in proximity to a rectal wall overlying a prostate, and inflate the membrane. As the user slides their finger across the rectal wall, optical fibers in the measurement assembly can move relative to a reference pattern, and a controller can sense light reflected through the fibers from the reference pattern. The controller can calculate or estimate various attributes of the prostate based on the reflected light, such as the palpable surface width or volume.
    Type: Application
    Filed: October 30, 2012
    Publication date: May 1, 2014
    Applicant: MedicalMetrix, Inc.
    Inventor: Christopher LaFarge
  • Patent number: 8712506
    Abstract: The present invention provides minimally invasive imaging probe having an optical encoder integrated therewith for accurately measuring or estimating the rotational velocity near the distal end of the medical device, such as an imaging probe which undergoes rotational movement during scanning of surrounding tissue in bodily lumens and cavities.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: April 29, 2014
    Assignee: Sunnybrook Health Sciences Centre
    Inventors: Brian Courtney, Nigel Robert Munce, Amandeep Singh Thind, Victor Xiao Dong Yang, Francis Stuart Foster
  • Publication number: 20140114197
    Abstract: A probe is shown. According to one implementation, the following is included at a tip of the probe, as the optical system. A first optical fiber system forms an irradiating light guiding path to guide irradiating light. A second optical fiber system forms a receiving light guiding path to guide measuring light. A condenser lens system is positioned opposed to the first optical fiber system and the second optical fiber system, and the irradiating light is irradiated thereon and the measuring light is condensed. An optical axis of the condenser lens system, a central axis of a light emitting end of the first optical fiber system, and a central axis of a light receiving end of the second optical fiber system are positioned so a straight line which passes through two axes does not pass through a remaining axis.
    Type: Application
    Filed: May 11, 2012
    Publication date: April 24, 2014
    Applicant: Konica Minolta, Inc.
    Inventor: Shoichi Tao
  • Publication number: 20140114198
    Abstract: Provided is an optical connector plug of which housing is provided with: a first member that has at least a lower surface section that covers the lower side of a providing space in which an optical fiber and a ferrule are provided, a half of a back surface section from which the optical fiber is led out, and a half of a front surface section from which the ferrule is led out, and is composite-molded out of a thermoplastic resin; and a second member that has at least an upper surface section that covers the upper side of the providing space, the remaining half of the back surface section and the remaining half of the front surface section, and is composite-molded out of a thermoplastic resin into the same shape as the first member.
    Type: Application
    Filed: May 17, 2012
    Publication date: April 24, 2014
    Applicant: Konica Minolta, Inc.
    Inventors: Atsushi Sawada, Kikuo Iwasaka, Yasuyuki Natsuno
  • Publication number: 20140114196
    Abstract: A measurement probe has a fiber bundle formed by irregularly bundling a plurality of optical fibers, is detachably connected to a bio-optical measurement apparatus performing optical measurement to a biological tissue that is an object to be measured, and includes a recording unit 35 that records positional information related to positions of an illumination fiber that emits light from a light source of the bio-optical measurement apparatus as illumination light and of a light-receiving fiber that receives returned light of the illumination light reflected and/or scattered at the biological tissue, the positions being at an end face of the fiber bundle, the end face being at an end that is attached to the bio-optical measurement apparatus.
    Type: Application
    Filed: November 15, 2013
    Publication date: April 24, 2014
    Inventors: Kenji KAMIMURA, Kazuhiro GONO, Yoshimine KOBAYASHI, Takeshi SUGA, Masahiro KATAKURA, Ryosuke ITO
  • Publication number: 20140107496
    Abstract: A sensing catheter having an outer flexible sheath and a proximal section containing a sensing system having a sensing means, a radiant energy providing means and radiation transmitting means, preferably all housed within a fluid channel.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 17, 2014
    Applicant: PERCUVISION, LLC
    Inventors: Ake A. HELLSTROM, Errol O. SINGH
  • Patent number: 8700134
    Abstract: The present invention relates to an optical scanning apparatus and an optical scanning system The optical system includes an optical engine connected to an optical scanning probe The optical scanning probe images a sample at different lateral positions of the sample The optical scanning probe includes a housing having a longitudinal axis extending in a direction towards a sample to be scanned, a first base having a first moveable mirror supported thereon by a first cantilever connecting the first moveable mirror to the first base, a second base having a second moveable mirror supported thereon by a second cantilever connecting the second moveable mirror to the second base, and a support attaching the first and second bases so that the first moveable mirror and the second moveable mirror are disposed along the longitudinal axis apart from each other.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: April 15, 2014
    Assignee: Research Triangle Institute
    Inventors: Sonia Grego, Kristin Hedgepath Gilchrist, David Edward Dausch, Michael Kasper Lamvik
  • Patent number: 8700135
    Abstract: Provided is an imaging system which includes an optical fiber array probe unit integrated with an endoscope unit, thereby simultaneously measuring structural information and functional information of a sample. The optical fiber array probe unit includes an optical fiber array probe integrated with lenses including an optical fiber lens with a lens surface of a predetermined radius of curvature in which one ends of optical fibers are integrally connected with each other by heating a predetermined region including the one ends of two of the optical fibers using a heating means, as an optical fiber array probe integrated lens on which the light transmitted from the light source is incident and which guides light reflected from the sample, and a detector for selectively detecting the light transmitted from the optical fiber array probe integrated with lenses in a predetermined range of wavelength.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: April 15, 2014
    Assignee: Korea Basic Science Institute
    Inventors: Ki Soo Chang, Seon Young Ryu, Sun Cheol Yang, Geon Hee Kim, Hae Young Choi
  • Patent number: 8694079
    Abstract: Systems and methods are provided herein that generally involve measuring a prostate or other object. In some embodiments, a membrane can be sealed over a digit extension to form a closed volume. The closed volume can be inflated via an inflation tube, and a reference pattern can be disposed within the closed volume along with a measurement assembly. In use, a user can put on the glove, position the membrane in proximity to a rectal wall overlying a prostate, and inflate the membrane. As the user slides their finger across the rectal wall, optical fibers in the measurement assembly can move relative to a reference pattern, and a controller can sense light reflected through the fibers from the reference pattern. The controller can calculate or estimate various attributes of the prostate based on the reflected light, such as the palpable surface width or volume.
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: April 8, 2014
    Assignee: MedicaMetrix, Inc.
    Inventor: Christopher LaFarge
  • Publication number: 20140094688
    Abstract: The invention relates to an optic-based sensing assembly and a system incorporating the assembly and related use of the assembly. In particular, the invention relates to an optic-based catheter assembly and related system used to determine contact between a catheter and surrounding proximate environment, such as tissue. An embodiment of such a system may, for example, be used for visualization, mapping, ablation, or other methods of diagnosis and treatment of tissue and/or surrounding areas.
    Type: Application
    Filed: November 4, 2013
    Publication date: April 3, 2014
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Troy T. Tegg, Saurav Paul, Richard E. Stehr, Reed R. Heimbecher
  • Publication number: 20140081151
    Abstract: The present invention is directed to an apparatus and method for assisted removal of the cortex, capsule polishing and destruction and/or removal of other intraocular structures. More particularly, the present invention is directed to a surgical apparatus configurable for removal of the cortex and the polishing of the capsule during cataract extraction surgery.
    Type: Application
    Filed: September 17, 2013
    Publication date: March 20, 2014
    Inventor: Liviu B. Saimovici
  • Publication number: 20140081150
    Abstract: Methods for fabricating metal nano-particle embedded enhancement substrates used for surface enhanced Raman spectroscopy (SERS) including ion implanting metal nano-particles into the substrate and etching the substrate to partially expose the metal nano-particles. The resulting material is useful as a SERS substrate for detection of molecules adsorbed on it by surface enhanced Raman spectroscopy.
    Type: Application
    Filed: August 5, 2013
    Publication date: March 20, 2014
    Applicant: THE UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Wei-Kan Chu, Dharshana N. Wijesundera, Indrajith Rajapaksa
  • Publication number: 20140073950
    Abstract: A scanning endoscopic device includes an optical fiber allowing irradiation light guided from a proximal side fiber portion to a distal side fiber portion to exit from a distal end thereof, and an actuator section placed to a distal direction side of the proximal fiber portion. The scanning endoscopic device includes a light absorbing section absorbing beam light having directivity in one direction, and the light absorbing section includes a black filling member filling a space between the proximal side fiber portion and an outer envelope tube in radial directions.
    Type: Application
    Filed: September 11, 2013
    Publication date: March 13, 2014
    Applicant: OLYMPUS MEDICAL SYSTEMS CORP.
    Inventors: Nobuaki Akui, Yuji Sakai
  • Publication number: 20140073926
    Abstract: The invention generally relates to a continuous anesthesia nerve conduction apparatus and method thereof, and more particularly to a method and system for use in administering a continuous flow or intermittent bolus of anesthetic agent to facilitate a continuous or prolonged nerve block. In one embodiment, the apparatus includes a sheath having a proximal end, a distal end and at least one lumen extending from the proximal end to the distal end. The sheath also includes an embedded conductive element for transmitting an electrical signal from a proximal portion of the sheath to a distal portion of the sheath. A cannula is arranged in the at least one lumen of the sheath and has a distal end protruding from a distal portion of the sheath. The cannula is electrically coupled to at least a portion of the embedded conductive element and is configured to provide nerve stimulation.
    Type: Application
    Filed: May 18, 2012
    Publication date: March 13, 2014
    Inventors: Sundar Rajendran, Dan Joel Kopacz
  • Patent number: 8670813
    Abstract: Systems and methods are provided for probing an occluded body lumen, including a flexible conduit insertable into the body lumen, at least one delivery waveguide and at least one collection waveguide integrated with the flexible conduit and arranged to deliver and collect radiation about a distal end of said flexible conduit, at least one radiation source connected to a transmission input of the at least one delivery waveguide, at least one optical detector connected to a transmission output of at least one collection waveguide, a spectrometer connected with the at least one optical detector, and constructed and arranged to scan radiation and perform spectroscopy, and a controller programmed to process data from said spectrometer and provide information for directing said flexible conduit through obstacles within the occluded body lumen.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: March 11, 2014
    Assignee: Angiolight, Inc.
    Inventor: Jing Tang
  • Patent number: 8660637
    Abstract: A miniaturized spectrometer is adapted for placement within a body near tissue to be characterized. The spectrometer includes a light source and a plurality of light detectors. The light source generates light to illuminate the tissue. The detectors detect optical signals from the illuminated tissue and convert these optical signals to electrical signals. The miniaturized spectrometer can be disposed at the distal end of an interventional device. Optical conduits, such as fiber optic cables or strands, extending the length of the interventional device are not required when the miniature spectrometer is employed.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: February 25, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Robert J Crowley
  • Publication number: 20140039325
    Abstract: The present document describes a pressure guidewire comprising: a shaft tube with a proximal section; a middle section extending from the proximal section of the shaft tube, the middle section having greater flexibility than the proximal section; an inner hypotube installed substantially within the middle section for optimal mechanical properties; a pressure sensor with a communication means routed through the middle section and the proximal section; and a sensor housing for receiving the pressure sensor. There are also described methods for joining the inner hypotube to the shaft tube.
    Type: Application
    Filed: September 18, 2013
    Publication date: February 6, 2014
    Applicant: Opsens Inc.
    Inventor: Claude Belleville
  • Publication number: 20140039324
    Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough. The suture is thus fastened to the valve leaflet and the instrument is withdrawn from the heart chamber transporting the suture outside the heart chamber. The suture is anchored to the heart wall with proper tension as determined by observing valve operation with an ultrasonic imaging system.
    Type: Application
    Filed: May 21, 2013
    Publication date: February 6, 2014
    Inventor: Giovanni Speziali
  • Patent number: 8644913
    Abstract: The present invention relates to: (1) guidewire support/placement catheters; (2) support/placement catheters with imaging; (3) atherectomy catheters, (4) atherectomy catheters with imaging, (5) occlusion crossing catheters, and (6) occlusion crossing catheters with imaging as well as methods for using them to treat disorders (and particularly peripheral artery disease) and systems including them.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: February 4, 2014
    Assignee: Avinger, Inc.
    Inventors: John B. Simpson, Himanshu N. Patel, Michael Zung, Charles W. McNall, Priyanshu Gupta, Maegan K. Spencer, Christopher B. White, Dennis W. Jackson, John F. Black
  • Patent number: 8644912
    Abstract: An apparatus to interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The apparatus includes a base unit having illumination, detection and control sub-units, the illumination sub-unit providing illumination optical energy for illuminating a target tissue and the detection sub-unit detecting tissue characteristics of a target tissue, a separate tissue interface unit, and a pathway coupling the base unit and the tissue interface unit. The system and apparatus may also include a tube for maintaining the distance between the tissue and units and for surrounding the tissue to prevent patient movement from being transmitted to the tissue.
    Type: Grant
    Filed: August 22, 2011
    Date of Patent: February 4, 2014
    Assignee: SpectRx, Inc.
    Inventors: Shabbir Bambot, Mark L. Faupel, Anant Agrawal, Keith D. Ignotz, Andrew Fordham
  • Publication number: 20140031702
    Abstract: A stereo colposcope having variable linearity filter systems for both the excitation step and the suppression step, and can be used universally with any fluorescent compound or drug, as is the case of photodynamic diagnosis (PDD). The colposcope is a two-way colposcope because the treatment can be administered by an optical system or by a light-producing radio-frequency electrical current with a diathermic effect which facilitates photodynamic treatment. The colposcope produces ozone, which has an antiseptic effect when applied to the genital tract. A monitor provides for three-dimensional viewing through the use of two video cameras with the DLP (Digital Light Processing) and HDTV (High Definition Television) systems with the use of active lenses.
    Type: Application
    Filed: April 15, 2011
    Publication date: January 30, 2014
    Inventors: Joel Gerardo Diaz Sanchez, Jose Gerardo Zertuche Zuani
  • Publication number: 20140024950
    Abstract: Methods and sensor delivery devices for monitoring a fluid pressure within a vascular structure, the devices including an elongated sheath sized for sliding along a guidewire, a sensor assembly including a fiber optic sensor, a housing surrounding the sensor, a first cavity between the distal end of the sensor and a distal aperture of the housing, a filler extending from at least the distal end of the housing distally and tapering inward toward the outer surface of the sheath, a second cavity in the filler with an opening at the outer surface of the filler and adjoining the distal aperture of the housing, and an optical fiber. The sensor delivery device may also include an outer layer that partially covers the second cavity with an aperture over the opening of the second cavity.
    Type: Application
    Filed: March 14, 2013
    Publication date: January 23, 2014
    Inventors: Jason F. HILTNER, Simon FURNISH, James Lamar GRAY, II, William K. DIERKING, Alan EVANS
  • Publication number: 20140024931
    Abstract: In part, the invention relates to systems, methods, and devices that store and retrieve information associated with an imaging probe such as an ultrasound probe, an optical coherence tomography probe, a multimodal probe and other probes. The information that is stored relates to one or more measurable properties for a specific imaging probe. Thus, when each probe is manufactured there can be variations in its length, brightness, angular alignment of its constituent elements, and various other probe specific measurements. In turn, these measurements can be used to calibrate or otherwise use a given probe with a system that collects, stores, or otherwise processes information collected using each probe.
    Type: Application
    Filed: July 20, 2012
    Publication date: January 23, 2014
    Applicant: LIGHTLAB IMAGING, INC.
    Inventors: David Winston, Paul Murray, Victor Grinberg, Marc Davidson
  • Publication number: 20140024951
    Abstract: A vision system that may be used in a catheter or similar guiding instrument includes receptors distributed in an annular area. Each of the receptors has a field of view covering only a portion of an object environment, and the field of view of each of the receptors overlaps with at least one of the fields of view of the other receptors. A processing system can receive image data from the receptors and combine image data from the receptors to construct a visual representation of the entirety of the object environment.
    Type: Application
    Filed: July 18, 2013
    Publication date: January 23, 2014
    Inventors: Peter M. HERZLINGER, Giuseppe Maria Prisco, Vincent Duindam, David Q. Larkin
  • Patent number: 8630697
    Abstract: The present invention provides for the detection and display of polarization scrambling tissue without resolving the polarization state of the backscattered imaging beam. In one embodiment, we illuminate the tissue using two different polarizations. A first polarization determines a first image of high intensity while the second polarization determines a second image of low intensity. Comparison and combination of the first and second images determines tissue which scrambles the polarization in neighboring detection cells.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: January 14, 2014
    Assignee: Carl Zeiss Meditec, Inc.
    Inventors: Scott A. Meyer, Xing Wei
  • Patent number: 8630698
    Abstract: A fluorescence endoscopy video system includes a multi-mode light source that produces light for white light and fluorescence imaging modes. A filter is positioned at the distal end of an imaging endoscope so that the endoscope can produce fluorescence and white light images of a tissue sample.
    Type: Grant
    Filed: April 26, 2006
    Date of Patent: January 14, 2014
    Assignee: Novadaq Technologies, Inc.
    Inventors: John J. P. Fengler, Francis Regamey
  • Patent number: 8626273
    Abstract: White light and excitation light are applied to an internal body part. An electronic endoscope captures a normal image of the internal body part irradiated with the white light, and a special image of autofluorescence emitted from living body tissue of the internal body part irradiated with the excitation light. An object distance detector detects an object distance between a CCD and an inspection area of the internal body part based on the normal image. A binning processing section applies a binning process to the special image. There are two types of binning processes, i.e. an intensity adjustment process and a resolution adjustment process. In the intensity adjustment process, the binning number is increased with increase in the object distance. In the resolution adjustment process, the binning number is decreased with increase in the object distance. Which process to perform is determined by operation on a processing type selector.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: January 7, 2014
    Assignee: Fujifilm Corporation
    Inventors: Hiroshi Yamaguchi, Takayuki Iida, Hiroaki Yasuda, Takashi Murooka
  • Patent number: 8620409
    Abstract: A system and method for confocal imaging of tissue in vivo and in situ, e.g., for minimally invasive diagnosis of patients. A catheter is provided that has a dye carrier coupled to the distal end of a fiber optics bundle, which allows for the introduction of at least one fluorescent dye therein the dye carrier into a portion of the tissue of interest of a subject or patient when the dye carrier is selectively brought into contact with the portion of the tissue of interest. The resulting confocal images permit the acquisition of diagnostic information on the progression of diseases at cellular/tissue level in patients. Furthermore, a system for ECG-triggered image acquisition is provided.
    Type: Grant
    Filed: August 4, 2009
    Date of Patent: December 31, 2013
    Assignee: University of Utah Research Foundation
    Inventors: Frank B. Sachse, John H. Bridge, Robert Hitchcock
  • Publication number: 20130338510
    Abstract: An apparatus for applying electro-magnetic radiations to a sample is provided. The apparatus can include an arrangement which has a specific portion with a plurality of channels. One channel(s) can facilitate a first radiation to be forwarded to the sample within an anatomical structure, and another channel(s) can facilitate a second radiation to be forwarded to the sample. The first radiation can have a first wavelength band, and the second radiation can have a second wavelength band, which can be substantially different from the first wavelength band. The first radiation can be delivered to a first area of the sample, and the second radiation can be delivered to a second area of the sample. Each of the channels can facilitate a particular radiation(s) to be forwarded to the sample that is within an anatomical structure of the sample, the radiations being delivered to different areas of the sample.
    Type: Application
    Filed: May 24, 2013
    Publication date: December 19, 2013
    Applicant: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Milen Shishkov, Brett Eugene Bouma, Benjamin J. Vakoc
  • Publication number: 20130331709
    Abstract: An imaging device includes a grin lens having a proximal end and a distal end, wherein the grin lens is made from a polymeric material, an optical fiber having a distal end coupled to the proximal end of the grin lens, and a beam director coupled to the distal end of the grin lens, wherein the beam director is configured to direct light at an angle relative to a longitudinal axis of the optical fiber.
    Type: Application
    Filed: June 7, 2012
    Publication date: December 12, 2013
    Applicant: PoinCare Systems, Inc.
    Inventors: Anthony Van LE, Nicholas John Richardi
  • Publication number: 20130324858
    Abstract: An optical scanner, scanner apparatus, or scanner assembly, which may be particularly advantageous for use in a multiphoton microscope, includes a first drivable bending component, a second drivable bending component mounted perpendicularly to the first component, and at least one optical waveguide coupled one or both of the first and second bending components, wherein the at least one optical waveguide provides both a propagation path for a multiphoton excitation radiation delivery between a light source and a target and a multiphoton-induced emission radiation delivery between the target and a detector. A GRIN relay lens. A multiphoton microscope incorporating the scanner and the GRIN relay lens.
    Type: Application
    Filed: December 8, 2011
    Publication date: December 5, 2013
    Applicant: CORNELL UNIVERSITY
    Inventors: Chunhui (Chris) Xu, Watt W. Webb, Douglas S. Scherr, Dimitre Gueorguiev Ouzounov, David R. Rivera, Christopher M. Brown, Demirhan Kobat, David Huland, Scott S. Howard
  • Publication number: 20130317372
    Abstract: In an example, this document discloses an apparatus for insertion into a body lumen, the apparatus comprising an optical fiber pressure sensor. The optical fiber pressure sensor comprises an optical fiber configured to transmit an optical sensing signal, a temperature compensated Fiber Bragg Grating (FBG) interferometer in optical communication with the optical fiber, the FBG interferometer configured to receive a pressure and modulate, in response to the received pressure, the optical sensing signal, and a sensor membrane in physical communication with the FBG interferometer, the membrane configured to transmit the received pressure to the FBG interferometer.
    Type: Application
    Filed: May 24, 2013
    Publication date: November 28, 2013
    Applicant: Vascular Imaging Corporation
    Inventors: Michael J. Eberle, Diana Margaret Tasker, Howard Neil Rourke
  • Publication number: 20130310698
    Abstract: In one aspect, the invention relates to a computer-implemented method of triggering optical coherence tomography data collection. The method includes collecting optical coherence tomography data with respect to a vessel using an optical coherence tomography probe disposed in the vessel; determining a clearing radius and a quality value for each frame of optical coherence tomography data collected for the vessel using a computer; determining if a blood clearing state has occurred using at least one clearing radius and at least one quality value; and generating a trigger signal in response to the blood clearing state.
    Type: Application
    Filed: February 28, 2013
    Publication date: November 21, 2013
    Applicant: LightLab Imaging, Inc.
    Inventors: Neil Judell, Robert Steinbrecher, Joel Friedman, Christopher Petersen
  • Publication number: 20130310680
    Abstract: A system and method for use in tissue analysis and therapy. An optical probe array has at least two or more optical probes for illuminating tissue and generates light fluorescence and/or diffuse reflectance signals corresponding to the illuminated tissue. One or more ultrasound, CT and MRI imaging guidance systems identify the position of the optical probes relative to the tissue. The imaging guidance system can also be a fusion of an MRI or CT image provided by the MRI or CT imaging guidance system and an ultrasound image provided by the ultrasound imaging guidance system. An imaging system generates a three-dimensional image of the tissue based on the generated light signals and the identified position of the optical probes.
    Type: Application
    Filed: May 20, 2013
    Publication date: November 21, 2013
    Inventors: Priya N. Werahera, Amir Tehrani, Edward Jasion
  • Patent number: 8583218
    Abstract: An elongated optical guidewire assembly, such as for optically imaging a patient from within another catheter, can have a lead portion and a probe portion. A connector between the lead and probe portions can include a bore including first and second bore ends. The first bore end can include a substantially circular cross-sectional profile. The second bore end can include a substantially non-circular cross-sectional profile. The bore can be configured to receive the optical guidewire assembly at the first bore end and configured to deform the optical guidewire assembly at the second bore end such that probe and lead ends of the optical guidewire assembly are deformed into a substantially non-circular profile and located between the first and second bore ends.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: November 12, 2013
    Assignee: Vascular Imaging Corporation
    Inventor: Michael J. Eberle
  • Patent number: 8571640
    Abstract: A method of characterizing conditions in a tissue, by (a) providing a catheter that has a light source that emits light in selected wavenumbers within the range of mid-IR spectrum; (b) directing the light from the catheter to an area of tissue at a location inside a blood vessel of a subject; (c) collecting light reflected from the location and generating a reflectance spectra; and (d) comparing the reflectance spectra to a reference spectra of normal tissue, whereby a location having an increased number of absorbance peaks at said selected wavenumbers indicates a tissue inside the blood vessel containing a physiological marker for atherosclerosis.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: October 29, 2013
    Assignee: The Regents of the University of California
    Inventor: Hoi-Ying N Holman
  • Patent number: 8565861
    Abstract: An optical inspection device 1, comprising a light generation means 2, a light irradiation means 3 irradiating an object to be inspected 4 with light generated from the light generation means 2 and a photodetection means 6 photoelectrically converting signal light obtained from the object to be inspected 4 through irradiation of light by the light irradiation means 3, and inspecting the object to be inspected 4 based on output from the photodetection means 6, wherein a light amplification means 5 amplifying signal light obtained from the object to be inspected 4 is provided. There is thus provided an optical inspection device capable of photoelectrically converting signal light from the object to be inspected with high sensitivity and promptly with its inexpensive configuration without increasing the intensity of light with which the object to be inspected is irradiated and without using an expensive low-noise and high-sensitivity photodetector.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: October 22, 2013
    Assignee: Olympus Corporation
    Inventors: Kenji Taira, Hiroyoshi Yajima, Shinichi Takimoto
  • Publication number: 20130274597
    Abstract: A scanner for an endoscope comprising: a scanning mechanism comprising a light transmitter and arranged to move the light transmitter to perform a scan; a lens system arranged to optically couple the light transmitter to a target during a scan; a first housing which houses at least a first portion of the lens system; a second housing which houses at least the fibre scanning mechanism; and a bendable joint joining the first and second housings such that in a scanning configuration the bendable joint joins the first and second housings so that optical elements in the first and second housings are aligned at a working separation, the bendable joint arranged to bend in response to insertion forces applied to the scanner during insertion of the scanner and revert to the scanning configuration in the absence of insertion forces.
    Type: Application
    Filed: October 12, 2011
    Publication date: October 17, 2013
    Applicant: OPTISCAN PTY LTD
    Inventors: Christopher Gerard Byrne, Robert Alan Pattie
  • Publication number: 20130267857
    Abstract: Probe with a light-receiving optical fiber having an entrance face on the tip orthogonal to first optical axis; a light-emitting optical fiber having an exit face on the tip that is orthogonal to a second optical axis; and a lens with a positive refractive power that projects light exiting from the exit face onto the measurement site of a living tissue and focuses light radiated from the measurement site of the living tissue onto the entrance face. Lens has convex surface facing the entrance face and exit face, a flat surface formed on the side opposite the convex surface, and a third optical axis. Distance from center of convex surface to first optical axis of optical fiber is shorter than distance from center to second optical axis of optical fiber.
    Type: Application
    Filed: December 14, 2011
    Publication date: October 10, 2013
    Inventor: Toshinori Takimura
  • Patent number: 8540627
    Abstract: The embodiments disclosed herein is related to a system for optical coherence tomographic imaging of turbid (i.e., scattering) materials utilizing multiple channels of information. The multiple channels of information may be comprised and encompass spatial, angle, spectral and polarization domains. More specifically, the embodiments disclosed herein is related to methods and apparatus for utilizing optical sources, systems or receivers capable of providing (source), processing (system) or recording (receiver) a multiplicity of channels of spectral information for optical coherence tomographic imaging of turbid materials. In these methods and apparatus the multiplicity of channels of spectral information that can be provided by the source, processed by the system, or recorded by the receiver are used to convey simultaneously spatial, spectral or polarimetric information relating to the turbid material being imaged tomographically.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: September 24, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Marc D. Feldman, Thomas E. Milner, Jung Hwan Oh, Eunha Kim, Karthik Kumar, Chris Condit, Robert Grant, Nate Kemp, Jeehyun Kim, Shaochen Chen, Li-Hsin Han