Measuring Pressure In Heart Or Blood Vessel Patents (Class 600/485)
  • Patent number: 11944417
    Abstract: The disclosure provides a wearing detection method, a wearable device, and a computer readable storage medium. The method includes: in response to determining that the wearable device is in a static state, emitting a plurality of first photoplethysmography (PPG) signals, and detecting a plurality of second PPG signals corresponding to the first PPG signals; obtaining a zero-crossing rate corresponding to the second PPG signals; and in response to determining that the zero-crossing rate of the second PPG signals is higher than a reference threshold, determining that the wearable device is in an unworn state.
    Type: Grant
    Filed: December 27, 2021
    Date of Patent: April 2, 2024
    Assignee: BOMDIC INC.
    Inventor: Yao Shiao
  • Patent number: 11925442
    Abstract: A system for measuring blood pressure information of a subject, and includes: an electrocardiogram detection unit for detecting an electrocardiogram of the subject; a pulse wave detection unit for detecting pulse waves of the subject; a first computation unit for computing a ventricular systolic phase pulse transit time on the basis of the R wave of the electrocardiogram waveform based on the potential detected by the electrocardiogram detection unit and the P wave of the pulse waveform detected by the pulse wave detection unit, and computing a ventricular diastolic phase pulse transit time on the basis of the T wave of the electrocardiogram waveform and the D wave of the pulse waveform.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: March 12, 2024
    Assignee: Arblet Inc.
    Inventor: Kosuke Shimizu
  • Patent number: 11918325
    Abstract: A system and method is disclosed for measurement of pulse wave velocity of a vessel. An intravascular device comprises a first and a second marker provided at different locations along the length of the intravascular device of which positions are localizable by a tracking apparatus. The intravascular device provides plurality of measurements along the length of the vessel, while the intravascular device is moved from a first position to a second position, corresponding to a first and a second time. At the second time the position of the first marker in the vessel corresponds to the position of the second marker at the first time. The pulse wave velocity value of the vessel is ascertained based on measurements associated for the first time and the second time from the plurality of measurements and based on the distance between the locations of the two markers along the length of the intravascular device.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: March 5, 2024
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Manfred Mueller, Arjen Van Der Horst
  • Patent number: 11911189
    Abstract: A method and apparatus for processing a biosignal is disclosed. The apparatus may extract reference points from a waveform of a biosignal, determine a pulse direction of the biosignal based on the extracted reference points, and determine a feature point of the biosignal based on a feature point determining method corresponding to the determined pulse direction of the biosignal.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: February 27, 2024
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Changmok Choi, Seungkeun Yoon, Ui Kun Kwon, Sang-Joon Kim
  • Patent number: 11896400
    Abstract: Provided are an electronic device for selectively storing blood pressure information and updating calibration data on the basis of the stored blood pressure information, and a control method. The electronic device comprises, a memory operably connected with the processor, wherein the memory can include instructions, during the execution thereof, for allowing the processor to, display a user interface on a display, allow the user interface to provide guidelines for measuring the blood pressure, receive first data from the motion sensor, receive second data from a PPG sensor, receive third data from the PPG sensor, determine the validity of the third data at least partially on basis of the first data and the second data, and display an indication on the user interface at least partially basis of the determined validity.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: February 13, 2024
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Sunghwan Cho, Jinho Kim, Seunghwan Shin, Junseok Oh, Inho Yun, Hongji Lee, Taehan Jeon
  • Patent number: 11883141
    Abstract: A biological information measurement apparatus includes: a pressure sensor including a pressure detecting element; a pressing mechanism which presses the pressure sensor against an artery in a living body; a press controller which controls a pressing force of the pressing mechanism; a blood flow sensor; a blood flow information measurer which measures blood flow information based on output of the blood flow sensor; a pressing force decider which decides a first pressing force based on blood flow information measured during a pressing force control time period when the pressing force is changed in one direction, and information of a pressure pulse wave detected during the pressing force control time period; and a record controller which records a pressure pulse wave detected in a first state where the pressing force is controlled to the first pressing force, and blood flow information measured in the first state.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: January 30, 2024
    Assignees: OMRON HEALTHCARE Co., Ltd., OSAKA UNIVERSITY
    Inventors: Yuki Kato, Shingo Yamashita, Toshihiko Ogura, Shunsuke Yoshimoto, Masataka Imura, Osamu Oshiro
  • Patent number: 11883230
    Abstract: A transcranial scanning device and method of use is disclosed. The transcranial scanning device is for identifying a neurologic-injury-mechanism and comprises a sensing wand comprising a transducer that produces and receives sound waves. The sensing wand is passed over a head of a patent with cerebral malaria, and sound waves reflect off of blood cells in blood vessels in the head of the patient creating an output sound wave responsive to a blood flow of the patient. The output sound wave is received by the transducer. An output screen coupled to the sensing wand, displays in real time an output waveform corresponding to the output sound wave, wherein the output waveform is indicative of one or more symptoms of cerebral malaria, and wherein said symptoms identify one or more neurologic-injury-mechanism occurring within the patient.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: January 30, 2024
    Assignee: The Research Institute at Nationwide Children's Hospital
    Inventor: Nicole Fortier O'Brien
  • Patent number: 11864912
    Abstract: The invention is related to a device to sense the pulse on a wrist of a subject and to arrive at the health status of the said subject by capturing the pulse in real time; analyzing the pulse based on time-frequency properties of the pulse signal and Vata, Pitta and Kaphahumors of the subject. The device reliably detects and captures noise free pulse characteristics of a subject at the appropriate locations of the subject's wrist with minimal positional error in a user friendly way with minimal reliance on the expertise of the person measuring the pulses. The device facilitates the analysis of the pulses and provides a comprehensive diagnostic system based on the pulse characteristics, visual features, responses of a subject to structured queries to arrive at the tridosha levels in a subject.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: January 9, 2024
    Assignee: ATREYA INNOVATIONS PRIVATE LIMITED
    Inventor: Aniruddha Jyeshtharaj Joshi
  • Patent number: 11850066
    Abstract: A system and method for measuring and monitoring blood pressure is provided. The system includes a wearable device and a tonometry device coupled to the wearable device. The Tonometry device is configured to compress a superficial temporal artery (STA] of a user. A sensor pad is attached to the wearable device adjacent the tonometry device. A blood pressure sensor is integrated within the sensor pad for continuous, unobtrusive blood pressure monitoring.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: December 26, 2023
    Assignee: The General Hospital Corporation
    Inventors: Quan Zhang, Yuanting Zhang
  • Patent number: 11844618
    Abstract: A system and method for cardiovascular monitoring and reporting are disclosed. The system (CV monitoring system) includes a data analysis system and an in-ear biosensor system that preferably includes left and right earbuds. The earbuds include infrasound/vibration sensors that detect biosignals from the individual including signals associated with cardiovascular activity (CV signals). The analysis system calculates cardiovascular function measurements (CV function measurements) based upon the CV signals. The CV monitoring system uses machine learning to predict blood pressure (BP) measurements of the individual based upon the CV signals and the calculated CV function measurements. In an embodiment, the CV monitoring system includes an EKG detection system that detects EKG signals associated with heart function.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: December 19, 2023
    Inventors: Anna Barnacka, Charles R Bridges, Siddharth Patel
  • Patent number: 11844591
    Abstract: One aspect of the subject matter described in this disclosure can be implemented in a device capable of use in estimating blood pressure. The device includes one or more arterial sensors configured to obtain arterial measurements at two or more elevations. The device additionally includes one or more processors configured to determine one or more calibration parameters for a first blood pressure model based on the arterial measurements and a hydrostatic pressure difference between at least two of the elevations. The processors also are configured to determine a first blood pressure based on the first blood pressure model, the calibration parameters and the arterial measurements. The processors also are configured to determine a second blood pressure based in part on a second blood pressure model, one or more calibration parameters and the arterial measurements. The processors are further configured to provide a final blood pressure based on the first and second blood pressures.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: December 19, 2023
    Assignee: QUALCOMM Incorporated
    Inventors: David Boettcher Baek, Lars Lading
  • Patent number: 11830624
    Abstract: The system for cardiovascular parameter data quality determination can include a user device and a computing system, wherein the user device can include one or more sensors, the computing system, and/or any suitable components. The computing system can optionally include a data quality module, a cardiovascular parameter module, a storage module, and/or any suitable modules. The method for cardiovascular parameter data quality determination can include acquiring data and determining a quality of the data. The method can optionally include processing the data, and/or determining a cardiovascular parameter, training a data quality module, any suitable steps.
    Type: Grant
    Filed: September 7, 2022
    Date of Patent: November 28, 2023
    Assignee: Riva Health, Inc.
    Inventors: Tuhin Sinha, Mark Mozolewski
  • Patent number: 11825206
    Abstract: Examples of the disclosure relate to at least apparatus, methods, and computer programs, configured to control capture of two images of an area, across which a pulse propagates, using different shutter scanning directions. Either the images are converted into pulse-phase maps of the area and a pulse-phase difference map obtained which identifies differences between the pulse-phase maps of the area, or a colour difference map is obtained which identifies differences between the two images and the colour difference map is converted into a pulse-phase difference map. A shutter-time difference map is obtained which identifies differences between capture times of corresponding locations in the two images. Using the shutter-time difference map, the pulse-phase difference map is corrected to obtain a map of pulse-phase changes which have occurred over a duration of a shutter scan.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: November 21, 2023
    Assignee: Nokia Technologies Oy
    Inventors: Christopher Wright, Harry Cronin, Phil Catton, William Schnabel
  • Patent number: 11813086
    Abstract: A measurement system includes: a sensor wire comprising an insertable portion configured to be inserted in a blood vessel of a patient's body; a sensor disposed at the insertable portion at a distal end of the sensor wire, wherein the sensor is configured to provide an output indicative of a temperature in the blood vessel of the patient's body, when inserted inside the blood vessel of the patient's body; and a transceiver unit configured to transfer information related to the output of the sensor to an external communication module using a frequency hopping technique. The transceiver unit comprises a housing adapted to be connected to a proximal end of the sensor wire and configured to remain external to the patient's body.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: November 14, 2023
    Assignee: ST. JUDE MEDICAL COORDINATION CENTER BVBA
    Inventors: Magnus Samuelsson, Sauli Tulkki
  • Patent number: 11800985
    Abstract: The present invention provides an electrocardiographic monitoring device comprising a device body configured to be attached to a user's chest; a plurality of electrodes provided on the device body; and a controller provided on the device body and connected to the electrodes in order to obtain the user's electrocardiographic signal waveforms. The electrocardiographic monitoring device of the invention can be applied in a blood pressure monitoring system for monitoring a user's blood pressure.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: October 31, 2023
    Assignees: BIV MEDICAL, LTD.
    Inventors: Shiming Lin, Shih-Wei Chiang, Cheng-Yan Guo, Tai-Cun Lin, Wei-Chih Huang, Chun-Nan Chen, Ya-Ting Chang
  • Patent number: 11793465
    Abstract: A display device includes: a display panel including a first area having a first light transmissivity and a second area having a second light transmissivity higher than the first light transmissivity; a pressure sensor overlapping the first area; a light emitter overlapping the second area; a light receiver overlapping the second area and spaced from the light emitter; and a processor to control the light emitter and the pressure sensor, and to output a blood pressure signal on a basis of a pressure sensing signal from the pressure sensor and a light sensing signal from the light receiver.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: October 24, 2023
    Assignee: Samsung Display Co., LTD.
    Inventors: Won-Ki Hong, Hee Seomoon, Hyeon Jun Lee
  • Patent number: 11786179
    Abstract: A bio-signal measuring apparatus includes: a substrate; a pulse wave measurer provided at the substrate and configured to measure pulse waves of a subject; and a pressure measurer provided at the substrate and configured to measure a contact pressure between the subject and the pulse wave measurer.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: October 17, 2023
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Chang Mok Choi, Byung Hoon Ko, Young Soo Kim, Jong Wook Lee, Youn Ho Kim
  • Patent number: 11779230
    Abstract: Current oscillometric devices for monitoring central blood pressure (BP) maintain the cuff pressure at a constant level to acquire a pulse volume plethysmography (PVP) waveform and calibrate it to brachial BP levels estimated with population average methods. A physiologic method was developed to further advance central BP measurement. A patient-specific method was applied to estimate brachial BP levels from a cuff pressure waveform obtained during conventional deflation via a nonlinear arterial compliance model. A physiologically-inspired method was then employed to extract the PVP waveform from the same waveform via ensemble averaging and calibrate it to the brachial BP levels. A method based on a wave reflection model was thereafter employed to define a variable transfer function, which was applied to the calibrated waveform to derive central BP.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: October 10, 2023
    Assignee: Board of Trustees of Michigan State University
    Inventors: Ramakrishna Mukkamala, Keerthana Natarajan, Jin-Oh Hahn
  • Patent number: 11779228
    Abstract: A bio-signal measurement apparatus may include a first substrate and a second substrate, an optical sensor mounted in the first substrate, a force sensor disposed on or below the first substrate, and a separation structure interposed between the first substrate and the second substrate so as to prevent transmission of a force between the first substrate and the second substrate. An upper surface of the first substrate and an upper surface of the second substrate may be provided at the same level.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: October 10, 2023
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Byung Hoon Ko, Yong Joo Kwon, Young Soo Kim, Sang Yun Park, Jong Wook Lee, Chang Mok Choi, Jae Min Kang, Youn Ho Kim
  • Patent number: 11751814
    Abstract: An apparatus for estimating biological information of a user may include a light source configured to emit light to an object of the user; an image sensor comprising a pixel array, and configured to acquire successive image frames by detecting light scattered or reflected from the object of the user; and a processor configured to: select a predetermined number of pixel-rows from among pixel-rows of the image sensor, detect signal intensities in the predetermined number of pixel-rows for each image frame of the successive image frames, correct the signal intensities, combine the signal intensities for each image frame of the successive image frames based on correcting the signal intensities, acquire a photoplethysmogram (PPG) signal based on combining the signal intensities, and estimate the biological information of the user based on the PPG signal.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: September 12, 2023
    Assignees: SAMSUNG ELECTRONICS CO., LTD., POSTECH Research and Business Development Foundation
    Inventors: Young Soo Kim, Sung-Min Park, Youn Ho Kim, Vega Pradana Rachim, Sang Yun Park, JinHyeok Baek
  • Patent number: 11744476
    Abstract: A blood pressure measurement device may include one or more piezoelectric sensors (e.g., differential piezoelectric sensors) for detecting blood flow through a limb of a user as part of determining blood pressure measurements. The piezoelectric sensor(s) may additionally or alternatively be used to determine one or more biological parameters of users (e.g., a ballistocardiogram, a heart rate, a heart rate variability, and a pulse wave velocity). The blood pressure measurement device may additionally or alternatively include a capacitive sensor for determining a pressure applied to the limb of the user by the blood pressure measurement device and/or operational states of the blood pressure measurement devices (off-arm, on-arm, inflating, deflating, tightness, and the like).
    Type: Grant
    Filed: August 20, 2020
    Date of Patent: September 5, 2023
    Assignee: Apple Inc.
    Inventors: Wegene H. Tadele, Makiko K. Brzezinski, Riley E. Brandt, Siddharth Nangia
  • Patent number: 11737723
    Abstract: The embodiments herein provide a system for calibration-free cuff-less evaluation of blood pressure. The system includes an ultrasound-based arterial compliance probes and a controller unit connected to the said probe. The ultrasound transducers are configured to measure the change in arterial dimensions, pulse wave velocity, and other character traits of an arterial segment over continuous cardiac cycle, which is then used to evaluate blood pressure parameters without any calibration procedure using dedicated mathematical models.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: August 29, 2023
    Assignee: HEALTHCARE TECHNOLOGY INNOVATION CENTER
    Inventors: Nabeel Pilaparambil Mashood, Jayaraj Joseph, Mohanasankar Sivaprakasam, Vangapandu Raj Kiran
  • Patent number: 11712168
    Abstract: The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the blood pressure of a subject based on physiological features and personalized models. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing a pulse wave relating to heart activity of a subject may be received. A plurality of second signals representing time-varying information on a pulse wave of the subject may be received. A personalized model for the subject may be designated. Effective physiological features of the subject based on the plurality of second signals may be determined. A blood pressure of the subject based on the effective physiological features and the designated model for the subject may be calculated.
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: August 1, 2023
    Assignee: Vita-Course Technoloaies (Hainan) Co., Ltd.
    Inventors: Ying Lu, Chuanmin Wei, Heng Peng, Jiwei Zhao, Ziming Deng, Zijian Huang
  • Patent number: 11701092
    Abstract: A fully automated ultrasound apparatus includes a sensor or probe which can be initially manually attached to a side of the neck of a patient, an ultrasound interface to control the sensor and periodically acquire raw ultrasound data, a signal and image processing system to autonomously convert the raw ultrasound data into a measurement that is useful to physicians, and a display to relay the current measurements and measurement history to provide data trends. The sensor can include one or more ultrasound transducers built into a housing. A disposable component can serve to secure the sensor to the neck of the patient and to provide a coupling medium between the sensor and the skin of the patient.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: July 18, 2023
    Assignee: REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Grant Kruger, Torben K. Becker, Nikhil Theyyunni, Ross Kessler, Bradley Plummer, Matthew Tafoya, Chelsea Tafoya, Steven E. Harte
  • Patent number: 11666233
    Abstract: A system and method for monitoring the blood pressure of a patient that allows for a device sensor to be recalibrated according to atmospheric pressure without removing the device sensor from inside the patient. This permits quickly monitoring the blood pressure of a patient if a re-zero is needed. The invention has a blood pressure monitor (BPM) that obtains an atmospheric pressure observation. The atmospheric pressure observation is adjusted and stored to memory as a zero value. The zero value is retrieved to recalibrate the system and method if a device sensor has been disconnected from and reconnected to the same or a different BPM, the patient has been moved such that the surroundings have been altered to make it necessary to recalibrate according to atmospheric pressure, and/or the device sensor has been connected to a different patient care monitor.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: June 6, 2023
    Assignee: Endophys Holdings, LLC
    Inventor: Phillip D. Purdy
  • Patent number: 11627884
    Abstract: [Subject] Non-invasive method for estimating blood pressure without a cuff and a device for the blood pressure estimation [Resolution means] Systolic blood pressure (EBP) is estimated according to EBP=?1·P1+?2·P2+?0 (?1, ?2, and ?0 are coefficients) where parameter P1, which is related to pulse transit time (PTT), and parameter P2, which is related to stroke volume based on pulse waves, are variables.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: April 18, 2023
    Assignee: Health Sensing Co., Ltd.
    Inventors: Masatomo Kanegae, Kyuichi Niizeki
  • Patent number: 11622693
    Abstract: Various examples are provided for non-contact vital sign acquisition. Information can be provided regarding vibrations of a target using a radar signal such as, e.g., non-contact vital sign measurement. Examples include estimation of heart rate, change in heart rate, respiration rate, and/or change in respiration rate, for a human or other animal. Implementations can produce one or both rates of vibration and/or change in one or both rates of vibration for a target other than an animal or human experiencing two vibrations at the same time, such as a motor, a vehicle incorporating a motor, or another physical object. Some implementations can estimate the respiration movement in the radar baseband output signal. The estimated respiration signal can then be subtracted from radar signals in the time domain and, optionally, can be further enhanced using digital signal processing techniques, to produce an estimate of the heartbeat pulses.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: April 11, 2023
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Jenshan Lin, Changyu Wei
  • Patent number: 11622692
    Abstract: A signal processing apparatus includes a memory configured to store instructions; and a processor configured to execute the instructions to obtain a signal; obtain a frequency band spectrum by applying a Fast Fourier Transform (FFT) to the obtained signal; and remove noise from the obtained spectrum by applying a first filter and a second filter, which are different from each other, to the obtained frequency band spectrum.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: April 11, 2023
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Chang Mok Choi, Dae Geun Jang
  • Patent number: 11617594
    Abstract: An endoscopic instrument for use with a trocar, said endoscopic instrument comprising an elongate shaft body having a proximal end and a distal end; an end effector assembly at said distal end operable by manipulation of actuator mechanism at said proximal end; a substrate core having a first surface and a second surface; at least one sensing element on said first surface, said at least one sensing element located adjacent to said distal end; an electronics module for receiving sensed signals from said at least one sensing element, said electronics module located adjacent to said proximal end; a first conductive layer residing on said first surface, said first conductive layer having first solder mask coated thereon; a second conductive layer residing on said second surface, second conductive layer having a second solder mask coated thereon, and wherein said second conductive layer coupled to said at least one sensing element relays said sensed signals from said at least one sensing element to said electronic
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: April 4, 2023
    Assignee: Forcen Inc.
    Inventors: Robert Brooks, Justin Wee, Justin Gerstle, Thomas Looi, James Drake
  • Patent number: 11617563
    Abstract: The present invention relates to a method and system for determining a central pulse wave velocity in a pregnant woman. The method comprises receiving an indication of a measurement of a length of a human aortic path outside the body to provide an aortic length, arranging a sound transducer at the position of the anatomical projection of the uterine artery, identifying the opening of the maternal aortic valve with measurement from the sound transducer as a first time, and the pulse wave arrival time at the uterine artery with measurements from the sound transducer as a second time, determining the central transit time based on the difference between the second time and the first time, and calculating the central pulse wave velocity based on the aortic length and the central transit time.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: April 4, 2023
    Assignee: VIEWCARE TECHNOLOGIES 1 APS
    Inventors: Diana Kjær Thing Riknagel, Johannes Jan Struijk
  • Patent number: 11612357
    Abstract: A blood pressure monitor cuff is formed by stacking an outer circumferential layer arranged on a side opposite to that of a measurement site and a fluid bladder arranged on the measurement site side. The outer circumferential layer and the fluid bladder are formed of an elastomer material. Two edge portions in a lengthwise direction of the outer circumferential layer protrude in a thickness direction toward the measurement site. The fluid bladder includes a base layer that opposes the outer circumferential layer and a top layer overlapping with the base layer, and the edge portions of the base layer and the top layer are welded together forming a bladder shape. Additional sheets are welded in the thickness direction to the welded edge portions of the top layer and the base layer. The fluid bladder is arranged between the two edge portions of the outer circumferential layer in the width direction.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: March 28, 2023
    Assignee: OMRON HEALTHCARE Co., Ltd.
    Inventors: Ryosuke Doi, Chisato Tawara, Takayuki Matsuoka, Yuichiro Arima, Yoshihide Tokko, Minoru Taniguchi, Yuma Adachi, Masayuki Fukutsuka
  • Patent number: 11596360
    Abstract: A system for collecting data for assessment of cardiovascular function includes a plurality of monitoring devices coupled to different respective body parts. Each monitoring device is configured to measure a respective signal at the respective body part in response to cardiovascular activity. The respective signal includes a cardiovascular component attributable to the cardiovascular activity and an artifact component not attributable to the cardiovascular activity. When the monitoring devices measure the respective signals simultaneously over a same time period, the cardiovascular components are correlated, and the artifact components are not correlated.
    Type: Grant
    Filed: June 22, 2020
    Date of Patent: March 7, 2023
    Assignee: Verily Life Sciences LLC
    Inventors: Andrew Homyk, Jason Donald Thompson
  • Patent number: 11589758
    Abstract: Disclosed are devices and methods for estimating blood pressure, which implement a pulse-transit-time-based blood pressure model that can be calibrated. Some implementations provide reliable and user friendly means for calibrating the blood pressure model using blood pressure perturbation methods and multiple sensors.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: February 28, 2023
    Assignee: Fitbit, Inc.
    Inventors: Alexandros A. Pantelopoulos, Thomas Samuel Elliot, Logan Niehaus
  • Patent number: 11574741
    Abstract: The systems and methods described herein determine metrics of cardiac or vascular performance, such as cardiac output, and can use the metrics to determine appropriate levels of mechanical circulatory support to be provided to the patient. The systems and methods described determine cardiac performance by determining aortic pressure measurements (or other physiologic measurements) within a single heartbeat or across multiple heartbeats and using such measurements in conjunction with flow estimations or flow measurements made during the single heartbeat or multiple heartbeats to determine the cardiac performance, including determining the cardiac output. By utilizing a mechanical circulatory support system placed within the vasculature, the need to place a separate measurement device within a patient is reduced or eliminated. The system and methods described herein may characterize cardiac performance without altering the operation of the heart pump (e.g., without increasing or decreasing pump speed).
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: February 7, 2023
    Assignees: Abiomed, Inc., Massachusetts Institute of Technology, The Brigham and Women's Hospital Inc.
    Inventors: Qing Tan, Ahmad El Katerji, Noam Josephy, Elazer R. Edelman, Brian Yale Chang, Steven Keller, Sonya Sanat Bhavsar
  • Patent number: 11564587
    Abstract: A system for detecting presence of coronavirus in a subject, the system including a first pad for placing a first hand, the pad including a contact to measure conductance of the subject's body, a conductance meter connected to the contact, a second pad for placing a second hand, a source of electromagnetic radiation for irradiating the second pad. A system for detecting presence of coronavirus in a subject, the system including a chip with a plurality of wires disposed on or in the chip, a conductance meter arranged to measure conductance between the wires, and biological material associated with the coronavirus disposed on or in the chip. Related apparatus and methods are also described.
    Type: Grant
    Filed: August 18, 2021
    Date of Patent: January 31, 2023
    Inventor: Dorit Arad
  • Patent number: 11529060
    Abstract: A method for providing personalized health assessment of a subject includes: receiving a raw electrocardiography (ECG) signal of a subject from an ECG device and a raw blood pressure (BP) signal of the subject from a BP waveform detector; calculating a beat-to-beat ECG signal from the raw ECG signal; calculating a beat-to-beat BP signal from the raw BP signal; calculating a beat-to-beat pulse arrival time (PAT) signal that is measured as a time delay between the beat-to-beat ECG signal and the beat-to-beat BP signal; calculating an interpolated beat-to-beat PAT signal and an interpolated beat-to-beat BP signal by interpolating the beat-to-beat PAT signal and the beat-to-beat BP signal, respectively; assessing a subject-specific relationship between the interpolated beat-to-beat PAT signal and the interpolated beat-to-beat BP signal; and estimating a real-time blood pressure of the subject based on the subject-specific relationship.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: December 20, 2022
    Inventors: Evelien Hermeling, Eva Wentink
  • Patent number: 11517740
    Abstract: The present invention is generally related to methods and systems for preventing onset or worsening of RHF in patients with implanted ventricular assist devices. More particularly, the present invention relates to identifying patients at risk for RHF following implantation of a ventricular assist device based on pulmonary artery pressure measurement and/or trends and adjusting a pump operating parameter to prevent or reduce the onset or worsening of RHF in such patients, improve patient outcomes, or reduce mortality risks associated with VAD implantation. In particular, a pump operating parameter may be adjusted to reduce or minimize particularly high pressure loads on a patient's heart or amount of time the patient is exposed to such high pressure loads following implantation.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: December 6, 2022
    Assignee: TC1 LLC
    Inventors: Rahul Agarwal, Allison Connolly, Yelena Nabutovsky, Julie Prillinger
  • Patent number: 11504508
    Abstract: Disclosed is an angioplasty balloon catheter and method of use, said angioplasty balloon catheter includes an elongated tip end with physical characteristics nearly identical to a standard angiographic diagnostic catheter. The elongated tip end extends approximately between 2 cm to 75 cm beyond a distal end of a balloon, depending upon embodiments. The tip of the elongated tip end may be angled or straight depending upon embodiments and may or may not have a plurality of side holes in addition to an end hole depending on embodiments. The elongated tip end permits the angioplasty balloon catheter to tract more easily across tortuous or markedly angulated segments of a dialysis graft or fistula, minimizing complications that can result with currently available devices. If angulated, the elongated tip end also enables a user to selectively catheterize an artery without needing a separate diagnostic catheter to do so, and enable tracking and cornering across sharply angulated vessel segments.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: November 22, 2022
    Inventors: Jonathan Levine, Timothy Murphy
  • Patent number: 11497454
    Abstract: An apparatus for estimating bio-information is disclosed. The bio-information estimating apparatus includes: a sensor configured to measure a bio-signal; and a processor configured to obtain one or more characteristic points, related to one or more pulse waveform components constituting the bio-signal, based on a differential signal of the bio-signal, and to estimate bio-information based on the obtained one or more characteristic points.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: November 15, 2022
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Chang Soon Park, Ui Kun Kwon, Seung Keun Yoon, Dae Geun Jang
  • Patent number: 11491300
    Abstract: A robot-connected IoT-based sleep-caring system includes a sleep-caring robot and an IoT system. The sleep-caring robot includes environment monitoring, physiology monitoring, sleep monitoring, sound, lighting and electricity control, a smart storage compartment, central data processing, and machine arms. The IoT system senses and executes instructions from the sleep-caring robot, thereby catering to bedroom activities of the user.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: November 8, 2022
    Inventor: Zhongtang Wang
  • Patent number: 11484210
    Abstract: Disclosed herein are methods and systems for a medical device that can monitor at least one chronic condition for example diabetes, with improved features that enable the device to detect the case while it is still pre diabetes, this early detection may significantly postpones the disease and minimizes complications with the change of life style, additionally it can advise those considered diabetics about their treatment protocol if it is sufficient or needs adjustment as the disease progresses.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: November 1, 2022
    Inventor: Waleed Bahaa El Deen Abdul Raheem Ahmed
  • Patent number: 11471063
    Abstract: A computerized information processing method for evaluating blood vessels is provided. The method includes acquiring a series of sequences of measurements, each at different time points in at least one cardiac cycle and at a different point along a blood vessel segment of a subject, generating corresponding profiles, calculating a transfer function for a subsegment between two selected points along a blood flow direction, and based thereon determining the physiological property of the subsegment. The measurements can contain information of blood velocity or blood pressure. A processing device and system implementing the information processing method are also provided. This approach can be used to evaluate arteries or veins and can be applied in screening, diagnosis, or prognosis of a variety of vascular diseases. For example, when combined with MRI scan, this approach can be used for non-invasively diagnosing pulmonary hypertension (PH) and chronic obstructive pulmonary disease (COPD), etc.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: October 18, 2022
    Assignees: Auburn University, Areus-Med, LLC, The UAB Research Foundation
    Inventors: Thomas S. Denney, Jr., Himanshu Gupta, Ankur Gupta
  • Patent number: 11426093
    Abstract: Persons with sleep disordered breathing (SDB) may, or may not, recognize that they have symptoms of SDB, and/or that they may be at-risk of, or suffering certain health problems associated with SDB, including death. The disclosed Energy Conversion Monitor (ECM) sensor, when embodied, for example, in a wearable upper-armband format, has been demonstrated to be more sensitive and responsive than pulse oximetry monitoring of blood oxygen saturation as an indication of hypoxic stress induced by SDB, and is compatible with: (1) inclusion in sleep laboratory polysomnograph (PSG) testing instrumentation, (2) home-based diagnostic testing for SDB, (3) control of home-use airway therapy devices, (4) continuous remote surveillance and refinement of airway therapy, and (5) spot-check and continuous surveillance of sleep quality in the general population. The disclosed ECM also provides new measurements of physiologic stress during and following exercise.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: August 30, 2022
    Assignee: REVEAL BIOSENSORS, INC.
    Inventor: Guy Meredith Hatch
  • Patent number: 11426130
    Abstract: An apparatus for non-invasively estimating blood pressure is provided. According to one embodiment, the apparatus for estimating blood pressure may include a bio-signal sensor configured to measure a bio-signal from a user and a processor configured to extract a feature from the bio-signal at an extraction time, acquire an offset based on a relative change value of the feature extracted at the extraction time, relative to a reference value of the feature obtained a time of calibration, and estimate blood pressure based on the relative change value of the extracted feature and the acquired offset.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: August 30, 2022
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Dae Geun Jang, Ui Kun Kwon, Chang Soon Park
  • Patent number: 11413005
    Abstract: The disclosed devices, systems and methods measure non-invasive blood pressure in a patient. Energy emissions, such as ultrasound or light, are emitted into tissues of the patient. The emitted energy reflects from various tissues, such as flowing blood and vessels, and can be detected, or received, to generate a reflected energy signal or data. The reflected energy can be processed, such as by using a constitutive equation, to calculate the blood pressure.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: August 16, 2022
    Assignee: Stryker Corporation
    Inventor: Clinton T. Siedenburg
  • Patent number: 11412987
    Abstract: The present application provides a personal hand-held monitor for the measurement of a subject's blood pressure and, optionally, one or more other vital signs, comprising a housing located on a personal hand-held computing device or a hand-held component of a computing system; a blood flow occlusion means located in the housing; a pressure sensor adapted to provide an electrical signal indicative of the pressure applied; a means for detecting the flow of blood in the body part of the subject when pressure is applied; and means for receiving electrical signals from the pressure sensor and the blood flow detecting means and for transmitting electrical signals indicative of the pressure and blood flow to the processor of the personal hand-held computing device or the computing system, wherein the processor of the personal hand-held computing device or computing system provide at least a measurement of the blood pressure of a subject.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: August 16, 2022
    Assignee: Leman Micro Devices SA
    Inventors: Christopher Elliott, Mark-Eric Jones, Mikhail Nagoga, Shady Gawad, Mark Bennett
  • Patent number: 11412955
    Abstract: A blood pressure measuring apparatus performs blood pressure measurement of a person to be measured. The apparatus includes: setting a measurement mode including at least a nocturnal blood pressure measurement mode to perform the measurement; and determining whether a blood pressure measurement posture is good under a first determination condition based on a height difference between a position of the apparatus and a heart position of the person in a sitting posture, and under a second determination condition based on a height difference between a position of the apparatus and a heart position of the person in a supine posture. A determination condition of the determining is switched to the second determination condition when the nocturnal blood pressure measurement mode is set.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: August 16, 2022
    Assignees: OMRON CORPORATION, OMRON HEALTHCARE CO., LTD.
    Inventors: Yuki Ota, Tsuyoshi Kitagawa, Shingo Yamashita
  • Patent number: 11412944
    Abstract: A method for measuring sound from vortices in the carotid artery comprising: first and second quality control provisions, wherein the quality control compares detected sounds to pre-determined sounds, and upon confirmation of the quality control procedures, detecting sounds generated by the heart and sounds from vortices in the carotid artery for at least 30 seconds.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: August 16, 2022
    Assignee: CVR Medical Corporation
    Inventors: Bret Kline, Peter Bakema, Young Truong, Richard Finlayson, Orville Day
  • Patent number: 11412940
    Abstract: The present invention provides a dynamic measurement device with a blood pressure determination function, comprising: a heartbeat sensing module disposed on the chest area of a user wherein the heartbeat sensing module comprising a heart sound sensor for obtaining heartbeat signals; a pulse sensing module disposed on a limb area of the user, the pulse sensing module comprising a pulse wave sensor for obtaining pulse signals; and a data calculating module for calculating a mean arterial pressure and a value of systolic blood pressure and diastolic blood pressure based on the heartbeat signals and pulse signals. In addition to dynamically monitoring the blood pressure of a user for 24 hours, the present invention can dynamically monitor the heart sounds of the user for 24 hours individually in order to monitor user's physical condition. Therefore, the present invention has important medical meanings.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: August 16, 2022
    Assignees: BIV MEDICAL, LTD.
    Inventors: Shiming Lin, Shih-Wei Chiang, Cheng-Yan Guo, Tai-Cun Lin, Wei-Chih Huang, Chun-Nan Chen, Ya-Ting Chang
  • Patent number: 11399725
    Abstract: A method and apparatus for monitoring a cardiovascular pressure signal in a medical device that includes determining whether the sensed pressure signal is greater than a first pressure threshold, determining a first metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, determining whether the sensed pressure signal is greater than a second pressure threshold not equal to the first pressure threshold, determining a second metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, and determining at least one of a systolic pressure or a diastolic pressure, wherein the at least one of a systolic pressure or a diastolic pressure is determined based on the first metric in response to the pressure signal not being greater than the second threshold, and based on the second metric in response to the pressure signal being greater than the second threshold.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: August 2, 2022
    Assignee: Medtronic, Inc.
    Inventor: Saul E. Greenhut