Abstract: An abdominal wound dressing and methods of use are described that enable the application of negative pressure to the wound site in a healing manner while also limiting the formation of adhesions that would prevent the removal of the dressing. The method comprises providing a flexible film having a plurality of holes therein and placing the flexible film in the wound. The flexible film has a first, patient-facing side and a second side. The method includes placing a porous pad on top of the second side of the flexible film. The flexible film and porous pad are sealed within the wound with a drape that is positioned in contact with an area of skin surrounding the wound. A negative pressure is provided to the porous pad for drawing a flow of exuded fluids from the wound.

Abstract: A method of manufacturing a wound dressing or the like comprises the steps of a) providing a layer of substrate material; b) extruding a curable hydrophobic gel precursor composition onto that substrate material via one or more mobile applicators; and c) causing or allowing the hydrophobic gel precursor composition to cure to form a hydrophobic gel. Wound dressings or the like that can be manufactured by such a method comprise a layer of substrate material, the wound facing surface of which carries bands of hydrophobic gel that are intermingled in a lattice-like arrangement.

Abstract: A wound dressing with a wound pad and a layer of vapour-permeable material arranged on top of the wound pad and extending peripherally outside the wound pad is described, wherein at least that part of the vapour-permeable layer extending peripherally outside the wound pad is coated with adhesive, and wherein the wound pad includes a liquid-retaining and liquid-transporting layer, and an upper distributing layer and lower distributing layer which bear against the top and underside, respectively, of the liquid-retaining and liquid-transporting layer.

Abstract: A resilient foam material having an active antimicrobial bound to, incorporated within, and projecting from its surface is provided for incapacitating or destroying microbes. The antimicrobial has an atomic structure that is capable of mechanically piercing or lysing a microbe thereby incapacitating or destroying the microbe. The resilient antimicrobial foam material may be manufactured into a resilient antimicrobial foam product for drawing across a surface and mechanically incapacitating or destroying microbes on the surface. The resilient antimicrobial foam material may be manufactured into a membrane for providing a sterile barrier for a surface. The resilient antimicrobial foam material is manufactured by combining the antimicrobial with a foam polymer material, heating the foam polymer material under pressure to a temperate that does not deactivate the antimicrobial, incorporating a blowing agent, cooling the material, and extruding the material.

Abstract: An offloading and reduced-pressure treatment system includes an offloading and reduced-pressure treatment device, which has a plantar member formed from an offloading manifold material. The offloading and reduced-pressure treatment system further includes a reduced-pressure interface fluidly coupled to the pressure-transmitting layer of the plantar member, a reduced-pressure source, and a reduced-pressure delivery conduit fluidly coupled to the reduced-pressure source and to the offloading and reduced-pressure treatment device. The offloading manifold material includes a first barrier layer, a support layer, a pressure-transmitting layer and a second barrier layer. The offloading and reduced-pressure treatment device may also have a dorsal member and a bridge member. Methods are also presented.

Abstract: A reduced pressure tissue treatment system includes an applicator having an aperture, a first pad section, and a second pad section substantially covering the aperture and positioned substantially adjacent the first pad section. A fabric layer is located at least partially between the second pad section and the drape, and the fabric layer includes a woven or non-woven fabric made from a fiber material. A drape substantially covers the first pad section, the second pad section, the fabric layer, and the applicator. A reduced pressure source is in fluid communication with at least one of the first pad section and the fabric layer for providing reduced pressure to the aperture.

Abstract: A wound dressing material comprising a solid substrate having interstitial spaces therein, wherein said substrate is a hydrophilic open-cell foam material, and wherein said interstitial spaces are at least partially filled by a hydrophilic polyurethane foam different from said substrate foam material. Also provided is a method of making a porous wound dressing material comprising the steps of: providing a substrate of a solid hydrophilic first foam material; applying a fluid or gel polyurethane foam prepolymer mixture to at least one surface of said solid substrate; and curing said prepolymer in contact with said solid substrate.

Abstract: The present invention provides a method for using a stabilized foam that is a crosslinked, closed cell polyolefin having a stabilizing layer and an adhesive layer. The method can be used for treating a wound, scrape, abrasion or skin puncture, for maintaining cleanliness of an operation incision site, suture site, catheter insertion site, or an intentional skin breach site, for monitoring electrical impulses during an EKG or for delivering electrical impulses in TENS or biofeedback therapy, and for reducing scar formation by softening collagen deposits.

Abstract: The invention relates to a device for negative pressure wound therapy comprising (a) a cover material for air-tight sealing of the wound space; (b) as applicable, a means for the connection of a negative pressure source; and (c) a wound dressing comprising (c1) an open-cell foam soaked with (c2) an ointment base, as well as a procedure for the manufacture of said wound dressing. The invention further relates to the use of an open-cell foam soaked with an ointment base for use as a wound dressing in negative pressure wound therapy.

Abstract: The invention relates to a device for negative pressure wound therapy comprising (a) a cover material for air-tight sealing of the wound space; (b) as applicable, a means for the connection of a negative pressure source; and (c) a wound dressing comprising an open-cell polyurethane foam whereby the open-cell polyurethane foam has special properties, in particular a tensile strength after three days of storage in bovine serum, measured in accordance with DIN 53571, between 80 kPa and 300 kPa. The invention further relates to the use of said open-cell polyurethane foam for use as a wound dressing in negative pressure wound therapy.

Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: A wound closure system and method having a porous pad for providing a reduced pressure to a tissue site is disclosed. The porous pad comprises a porous material formed by spraying a chemical substance that cures to form the porous material which has a body and an outer surface. Both the body and the outer surface have pores wherein the average size of the pores in the outer surface is smaller than the average size of the pores in the body. The porous pad further comprises a pathway formed within the porous material that is adapted to fluidly communicate with a source of reduced pressure.

Abstract: The invention provides a wound dressing comprising a layered material comprising a hydrophilic foam layer formed from a first polyurethane and a hydrogel layer formed from a second polyurethane, wherein the hydrogel layer is laminated to the hydrophilic foam layer. The invention also provides methods for preparing the same.

Abstract: The present invention relates to a wound packing material, suitable for use in negative pressure wound therapy, comprising a body of a porous material, the body comprising frangible regions defining a plurality of portions, the frangible regions allowing the portions to be selectively removed from the body. The invention further relates to methods of manufacturing the wound packing material, and to methods of its use.

Abstract: A biocompatible wound dressing comprised of a pad for insertion substantially into a wound site and wound drape for sealing enclosure of the foam pad at the wound site. The pad, comprised of a foam or other like material having relatively few open cells in contact with the areas upon which cell growth is to be encouraged so as to avoid unwanted adhesions, but having sufficiently numerous open cells so that drainage and negative pressure therapy may continue unimpaired, is placed in fluid communication with a vacuum source for promotion of fluid drainage, as known in the art. The pad is further comprised of an ultra-low density fused-fibrous ceramic, or a bioabsorbable branched polymer, or cell growth enhancing matrix or scaffolding.

Abstract: The present invention relates to a polyurethane foam dressing having excellent adhesive properties and a manufacturing method thereof, in which the polyurethane foam dressing has high capacities for absorption and retention of exudates so that it can be applied even to high-exudate wounds, and in which a hydrophilic adhesive is applied to the wound contact layer of the polyurethane foam dressing so that the foam dressing is advantageous for wound healing and is easily removed without causing pain. Specifically, the polyurethane foam dressing comprises a laminate of a sponge-like wound contact layer and a film-like protective layer, in which an adhesive layer is formed on the wound contact surface of the wound contact layer, wherein the adhesive layer consists of a hydrophilic adhesive composition comprising 100 parts by weight of a hydrophilic adhesive and 0.07-5 parts by weight of a binder.

Abstract: A method for manufacturing a diffusion dressing includes automated steps for pre-forming and precutting a first occlusive layer and precutting a permeable layer of material to a finished size, coating one side of the permeable layer with a permeable adhesive, placing precut sections of a cellular material layer onto the adhesive side of the permeable layer, sealing the first occlusive layer to the permeable layer, precutting a section of absorbent material to a finished size, coating the remaining side of the permeable layer with a permeable adhesive, placing the section of absorbent material on the coated side of the permeable layer, applying a seal about the periphery of the remaining side of the absorbent material, pre-forming and precutting an adhesion layer to a finished size, precutting a removable second occlusive layer of material to a finished size, and sealing the second occlusive layer against the adhesion layer.

Abstract: The invention relates to a wound dressing and methods of preparation and use thereof for promoting healing of a wound bed. In particular, the wound dressing is advantageous for application to a debrided wound bed. The wound dressing comprises an open conduit polymeric foam matrix, and a hydrophilic polymer which is disposed in dry form on the inner surfaces of the conduits within the matrix.

Abstract: Wound dressings and wound inserts comprising substantially dry reactive agents, methods of forming wound inserts comprising dry reactive agents, and wound-treatment methods.

Abstract: Dressings, systems, and methods for treating a tissue site on a patient involve allowing liquids from the tissue site or a priming fluid to evaporate and exit the dressing through a liquid-impermeable, vapor-permeable membrane. The dressing is able to process more liquids than would otherwise be possible without evaporation and potentially to create reduced pressure. Other dressings, systems, and methods are disclosed.

Abstract: A bandage system is provided that is capable of being held by an upstanding snap member attached to a wound site. The bandage system has a snap engaging member for coupling to the snap member. A cushion member is provided that has a wound engaging surface for overlaying the wound site. A pressure exerting base member is coupled to the base member for urging the cushion member into engagement with the wound site.

Abstract: Disclosed is a polyurethane foam dressing material with an excellent adhesive property, and a method for preparing the same, an object of the present invention is to provide an adhesive polyurethane foam dressing material and a method for preparing the same, in which the adhesive polyurethane foam dressing material has an excellent exudates adsorption degree and moisturizing rate available for applying the wounds with a lot of exudates, and a silicone/acryl adhesive applies on the wound contact side in order to have favorable for treating a wound, and easily remove without a pain.

Abstract: A wound dressing includes a wound-filling member attached to a hemostasis inducer that can be impregnated with an active compound, such as coagulants. The wound dressing can be placed in wounds to provide pressure, as well as chemical action, to promote blood coagulation and thereby arrest bleeding. A wrap can be attached to the wound dressing to provide an easy and quick method of securing the wound dressing. The wound dressing can be compressed in a small package for easy transport.

Abstract: A negative pressure (i.e., vacuum or suction) wound healing device and system incorporating the device. The device of the present disclosure is smaller, lighter, portable, and overall more manageable by both the user and the medical personnel than the conventional systems. The device could be readily worn by the user.

Abstract: An absorbent structure comprising a silicone foam having pore walls and a plurality of hydrophilic particles anchored to the pore walls of the foam. Some of the hydrophilic particles have an anchored portion firmly anchored to the pore walls and an exposed portion extending outwardly away from the pore walls upon which the anchored portion is secured.

Abstract: Embodiments disclosed herein are directed to the treatment of wounds using negative pressure. Some embodiments disclosed herein provide for a foam pad, which may be suitable for use in abdominal wound sites, and which may be sized in a dimensionally-independent manner. Additional embodiments provide for a wound contact layer, as well as a system for the treatment of abdominal wounds.

Abstract: This disclosure relates to a compression dressing designed to provide moisture transport properties to a contact surface and compression therapy for patients with swelling due to various medical conditions. The compression dressing is minimally comprised of at least one layer of moisture transport fabric comprised of elastic fiber that exhibits a sufficient amount of elasticity to apply a compressive force to a body part when applied thereto. The compression dressing further provides one-way, active fluid management which can move fluid away from the skin. The compression dressing may also include at least one absorptive reservoir layer that is applied to the outer surface of the moisture transport fabric. This absorptive reservoir layer may be removed as needed without substantially disrupting the compressive force applied to a body part. The method for using the compression dressing to manage fluid movement and edema is also provided.

Abstract: Foam wound inserts with high-density and low-density regions, methods for making wound inserts, wound-treatment methods, and wound-treatment systems.

Abstract: The present invention relates to a process for producing shaped articles comprising, acting on a foam layer in a first region with a pressure of from 0 to 150 bar at a temperature of from 0° C. to less than or equal to 200° C., whereby the foam layer is compressed in the first region to greater than 12.5% to 100% of its original volume; acting on the foam layer in a second region with a pressure of from 50 to 150 bar at a temperature of from 100° C. to 200° C., whereby the foam layer is compressed in the second region from greater than 0% to 12.5% of its original volume; and wherein the foam layer comprises in the first region and the second region a polyurethane foam which is obtained by foaming and drying a composition comprising an aqueous, anionically hydrophilicized polyurethane dispersion.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: An abdominal wound dressing and methods of use are described that enable the application of negative pressure to the wound site in a healing manner while also limiting the formation of adhesions that would prevent the removal of the dressing. The dressing comprises a layer of porous foam material enclosed by sheets of elastomeric material punctuated by a number of appropriately placed holes. Multiple layers of porous foam may also be used. A suction tube connector is provided on an upper surface of a layer of foam for connection to a negative pressure source. At least one layer of foam is enclosed in elastomeric material and is placed in direct contact with the tissue within the open wound. Fluids are drawn by negative pressure through the holes positioned in the elastomeric envelope and through the foam.

Abstract: For application of active substances to a wound surface a porous padding (12) is provided upon the wound (10), which is sealingly covered over with a foil (14). A fluid active substance is introduced into the padding (12) via a supply line (22) and is then suctioned out of the padding (12) via a removal line (26). Closure mechanisms (32, 34) control the introduction of the active substance and the suctioning off of the active substance in the manner, that the active substance after being introduced remains for a predetermined dwell time in the padding (12), before it is suctioned off. After the suctioning off the vacuum in the padding (12) is maintained for a certain time period, before renewed introduction of the active substance. The opening of the closure mechanisms (32, 34) are temporally controlled to occur slowly.

Abstract: A cushioning device for use on skin, such as on a finger or foot, comprising a cushioning layer having a skin side and an outer side and an ultra-hydrophilic pressure-sensitive adhesive layer coupled to the skin side of the cushioning layer.

Abstract: The present invention relates to a wound dressing including an outer layer of air-impermeable material and means for attaching the dressing to the skin surrounding a wound, a pre-compressed body of resilient material, said body creating a sub-pressure after attaching the dressing to a wound. According to the invention the pre-compressed body is enclosed in a casing of air-tight material, whereby at least a portion of said casing is made of a soluble material, which dissolves after contact with liquid exudate.

Abstract: A non-contact wound covering for covering a wound includes a peripheral sealing ring. The peripheral sealing ring is covered by a barrier layer and this assembly is attached to the skin with an adhesive. The barrier layer and peripheral sealing ring together define a treatment volume over the wound. Treatment fluid is introduced into the treatment volume through an inlet, and is exhausted therefrom through an outlet or an exhaust filter.

Abstract: The present invention relates to a wound dressing including a first wound pad and a first cover layer covering the first wound pad and extending beyond the first wound pad around the circumference thereof. According to the invention a second wound pad is disposed outside the first cover layer and enclosed in a second cover layer. Furthermore, the first and second wound pads are connected to each other by liquid transferring means.

Abstract: A wound dressing including an absorbent core defining opposed proximal and distal surfaces, the distal surface of the absorbent core defining a central portion, a border portion and an intermediate portion interposed between the central and border portions. The backing layer defines at least one compliant element disassociated from the distal surface of the absorbent core and including at least one ridge extending outwardly relative to the distal surface of the absorbent core.

Abstract: A preformed wound shield includes a frame formed of one or more layers of suitable material and any suitable covering. Exudate absorbing or transporting material may also be one of two or more layers of material forming the frame.

Abstract: A therapeutic device for promoting the healing of a wound in a mammal is disclosed. An exemplary device comprises a permeable structure having a plurality of depressions formed in a surface thereof. In use, the surface having the depressions is disposed adjacent a surface of the wound. A method of treating a wound comprises the steps of providing a permeable structure comprising a plurality of randomly disposed fibers and having i) a plurality of wound surface contact elements disposed between end portions of the structure, and ii) a plurality of voids defined by the contact elements; and applying the permeable structure to at least one surface of the wound.

Abstract: A breathable interface system including an applicator having an aperture therethrough; a drape substantially covering the applicator; a first pad section located between the drape and the applicator; a second pad section substantially covering the aperture and located between the drape and the applicator, the second pad section substantially adjacent to the first pad section; and a fabric layer located at least partially between the second pad section and the drape; and a reduced pressure conduit in communication with one of the first pad section and the fabric layer for providing reduced pressure to the aperture; wherein the drape is secured to the applicator, covering the first pad section, the second pad section, and the fabric layer in a substantially sealed environment.

Abstract: A stiffening layer (4) for facilitating application of a plastic film (2) to skin, the plastic film being a component in a wound dressing (1) or other medical device and having the stiffening layer (4) removably attached to one side thereof, at least a part of the other side of the film being provided with a layer of self-adhering adhesive (3). The stiffening layer (4) is made of a stretchable material having a thickness of between 0.5-10 mm. The stiffening layer covers the whole area of the film and is divided into two or more portions by cutting line or lines.

Abstract: Under one aspect, an apparatus includes a primary dressing configured for application over a region of compromised skin and including fluid-absorbing material; and a secondary dressing configured for application over the primary dressing. The secondary dressing applies pressure to the primary dressing so as to maintain the primary dressing in place over the region of compromised skin and promote the flow of fluid from the region of compromised skin into the fluid-absorbing material, and allows moisture in the fluid to evaporate from the fluid-absorbing material. Under another aspect, a dressing includes a fabric layer sized to cover a region of compromised skin; a foam layer secured to the fabric layer and having an aperture defined therein sized to cover the region of compromised skin; and a biocompatible adhesive layer disposed on the foam layer. Methods of applying the dressing also are provided.

Abstract: An absorbent structure comprising a silicone foam having pore walls and a plurality of hydrophilic particles anchored to the pore walls of the foam. Some of the hydrophilic particles have an anchored portion firmly anchored to the pore walls and an exposed portion extending outwardly away from the pore walls upon which the anchored portion is secured.

Abstract: The present invention provides devices and methods for treating wounds. The devices may include polymer particles capable of absorbing fluid such as blood. When devices of the invention are exposed to fluid, the fluid may enter the device and cause the polymer particles to swell. Devices of the invention may also apply pressure on wound cavities to stop or restrict the flow of fluid. In some embodiments, the devices may comprise components to facilitate absorption of fluid throughout the device, such as wicking elements and/or multiple compartments. One or more of the devices can be placed directly in the wound cavity, or in a containment structure and then into the wound cavity.

Abstract: A method of producing a hydrophilic polyurethane foam structure containing inert activated carbon particles, includes the steps of: (a) providing a water phase containing a surfactant and dispersed inert particles; (b) providing a isocyanate-terminated polyether having functionality of more than 2; (c) mixing the water phase and the isocyanate-terminated polyether, immediately transferring the resulting mixture to a mould or a continuous web, whereby a foam structure is obtained; and (d) drying the foam structure until it has a moisture content of at most 10% (wt). A foam structure produced by the method and a wound dressing containing the foam structure are also disclosed.

Abstract: A medical dressing comprising absorbent polyurethane foam wherein the foam comprises an antimicrobial agent, which can be released from the foam by the action of water. The antimicrobial agent is also used as a control of the resilience of the foam. The antimicrobial agent can be poly(hexamethylene biguanide)hydrochloride, also named PHMB or polyhexanide.

Abstract: To provide a patch containing fentanyl for mucous membrane of the oral cavity (oral transmucosal fentanyl), which rapidly increases the serum concentration of the drug, is easy in handling and is superior in safety. The patch can be prepared by laminating on one side of a drug layer which contains fentanyl or its salt as an active ingredient, methyl vinyl ether-maleic anhydride copolymer as an adhesive, and at least one substance selected from the group consisting of hydroxypropylcellulose, hydroxypropylmethylcellulose and hydroxyethylcellulose as a thickener, a support layer hardly soluble or insoluble in water, and a backing in this order.

Abstract: An apparatus for cleansing and promoting tissue growth in wounds, in which irrigant fluid optionally containing cell nutrients and/or other physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing, a biodegradable scaffold in contact with the wound bed and a means for fluid cleansing and back to the dressing. The apparatus has means for supplying thermal energy to the fluid in the wound. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing and a method of treatment using the apparatus.

Abstract: The invention relates to a production method for a foam wound dressing with an outer germ barrier, in particular a film layer, and to a wound dressing obtained by such a method. In the method according to the invention, the germ barrier is generated by means of extrusion directly on the foam support. This results in a more reliable union between foam layer and germ barrier, without thereby compromising the absorbency of the foam in respect of wound exudate. The proposed method is simple and inexpensive and is able to satisfy all the requirements of the medical sector (e.g. freedom from solvents).

Abstract: An adhesive skin protector that filters sunlight harmful to skin lesions. The protector includes at least one adhesive layer adapted to adhere to an area of skin having a skin lesion; and at least one filter layer attached to said adhesive layer, the at least one filter layer being adapted to filter sunlight harmful to the skin lesion.