Abstract: An ophthalmic device including a cannula having a cannula distal end, a lumen, and one or more orifices coupled to the lumen is provided. The cannula is configured to deliver a fluid. A sleeve is disposed around the cannula and has a sleeve distal end. A handle is coupled to the sleeve and the cannula, the handle having an actuator. An internal mechanism is coupled to the actuator and is configured to pump the fluid. The internal mechanism includes an inlet port disposed on a handle proximal end, a drive member coupled to the actuator and a plunger coupled to the drive member. The ophthalmic device is configured to retain a volume of fluid and to be prevented from being re-primed after a predetermined number of actuator presses, wherein the retained volume of fluid is dispensed over an additional number of actuator pushes.

Abstract: A drug storage and dispensing system that includes a packaging unit and an injection device for pre-filled containers having a needle shield and containing a medication is disclosed. The drug storage and dispensing system of the present disclosure provides for drug administration while minimizing the space occupied by such containers in the cold chain. The packaging unit minimizes the risk of a needle-stick injury, as a healthcare worker does not have to manually remove the needle shield. The injection device provides a novel way of auto-disabling a container, such as a syringe, as a plunger rod is not engaged with the container until the container is actually used. The drug storage and dispensing system provides for a reduction in the number of steps required to perform an injection, and thus a productivity and efficiency gain in mass immunization campaigns.

Abstract: An autoinjector for dispensing a liquid product, in particular a highly viscous medication, includes: a housing, a product container, which is arranged in the housing and has a slidable piston, wherein the piston can be slid in a dispensing direction in order to dispense the product contained in the product container, a forward drive element, which acts on the piston as the product is being dispensed, a first spring, which is preloaded such that the product can be dispensed from the product container by the sliding of the forward drive element and the piston, and a rotation element, which is operatively coupled to the forward drive element, wherein the first spring acts on the rotation element in such a way that the rotation element is set into rotation in order to dispense the product, wherein the rotation element or the forward drive element has a thread having a variable pitch.

Abstract: An auto-injector operable in a single activation step. The auto-injector is automatically armed when removed from its carrying receptacle. The auto-injector may be prefilled with more than one constituent of a beneficial agent, stored in separated compartments, in such an arrangement that the compartments will automatically merge when the auto-injector is removed from its carrying receptacle.

Abstract: A medicament delivery device is presented having a drive configured to act on a medicament container for expelling a medicament; a holder configured to hold said drive in a pre-tensioned state; an activator configured to interact with said holder for releasing said drive from the pre-tensioned state; wherein the device further includes a feedback mechanism configured to interact both with said holder and with said drive for generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.

Abstract: An autoinjector and method of injection are described. A power spring causes rotation of a drive nut about the central axis of the autoinjector that, in turn, causes a middle screw to rotate in the same direction as the drive nut and also to move in the distal direction while pushing a center screw in the distal direction that pushes the syringe and needle. The center screw also pushes a plunger that pushes the fluid out of the syringe. After injection, a locked retract screw is freed and rotates in the same direction as the middle screw causing the syringe to retract the syringe into the housing.

Abstract: A medicament delivery device is presented having a drive configured to act on a medicament container for expelling a medicament; a holder configured to hold said drive in a pre-tensioned state; an activator configured to interact with said holder for releasing said drive from the pre-tensioned state; wherein the device further includes a feedback mechanism configured to interact both with said holder and with said drive for generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.

Abstract: An injection device is disclosed for the administration of several medications. The injection device includes a carrying housing, an activation sleeve surrounding the carrying housing, at least two carpules, a first drive module for the administration of the medications, a securing device, a needle arrangement, a needle protection element, and a second triggerable drive module for the needle arrangement. The first drive module includes a drive element with a number of piston rods equal to the number of carpules. At least one of the piston rods is configured in the form of a hollow cylinder the is closed on the piston side, wherein arranged inside this is a first drive means of the first drive module. The first drive means can be arranged in an accommodation part of the drive element, wherein the accommodation part forms with the piston rods a composite structural unit.

Abstract: A medicament delivery device is presented having a housing that is arranged to accommodate a medicament container, a drive unit operably arranged to act on the medicament container upon activation, an activation mechanism operably arranged to be operated by a user, an activation preventing mechanism operably arranged to prevent the activation mechanism to be activated, an usage management module arranged to be operated by a user, which usage management module is designed as an attachable unit to the medicament delivery device. First keying elements are arranged on the device and on the usage management module designed to interact with each other when attaching said usage management module, such as to cause a deactivation of the activation preventing mechanism to allow operation of the activation mechanism. The usage management module can include a monitoring circuit arranged to monitor the use of the medicament delivery device.

Abstract: Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a main housing having an interior surface defining an enclosed space, and an exterior surface releasably attachable to a patient. A container may be disposed in the enclosed space and include a reservoir containing a drug and a stopper. A drive assembly may also be disposed in the enclosed space and configured to move the stopper through the reservoir to expel the drug from the reservoir. The drive assembly may include a rotational power source and a gear module. The gear module may include a mounting plate and a plurality of gears rotatably connected to the mounting plate. Furthermore, the mounting plate may be separate from the main housing.

Abstract: A medicament delivery device system for delivery of a medicament from a cartridge (10). The system comprises a first container (11) for storage of a first substance, a second container (12) received in the first container (11) for storage of a second substance, and valve means (68) for closing a distal end of the second container (12). The system further comprises a disposable cassette (102) and a reusable firing unit (200). The cassette (102) has a body (104) for receiving the cartridge (10), and a mixing element (148) for displacing the second substance into the first chamber (16) in a mixing stroke, to mix with the first substance to form the medicament. The firing unit (200) comprises a drive element (208) for expelling the medicament from the first chamber (16) in a delivery stroke and a trigger arrangement (240) for initiating the delivery stroke.

Abstract: A sensor insertion device comprises a main body, needle slider, disposal slider, spring, puncture knob, and opening mechanism (window member and handle). The needle slider grips a needle and a sensor on a first end side, and is slidable inside the main body. The disposal slider is slidable inside the main body. The puncture knob has an insertion hole into which the rear end portion of the needle slider can be inserted. The opening mechanism puts the insertion hole into a closed state when the needle slider is being slid in the sensor insertion direction, and, puts the insertion hole in an open state in which the second end side of the needle slider has been inserted into the insertion hole by opening up the contact portion between the puncture knob and the second end side of the needle slider when the puncture operation is complete.

Abstract: The present disclosure relates to apparatus, assemblies, combinations, and methods for infusing fluids by hollow microneedles.

Abstract: In some embodiments a system and method are described for safeguarding a hazard, the hazard, for example a needle point, may be moved between a protected retracted position, an active extended position and/or an intermediate position. Optionally in the retracted position, the hazard may be protected inside a housing. Optionally in the extended position, the hazard may be exposed. Optionally, in the intermediate position the hazard may be partially protected and/or concealed, for example by a shield and/or in an indentation. In some embodiments, compromising a shield causes the hazard to be retracted to the retracted position.

Abstract: The present disclosure relates to a medicament injection device comprising a housing, a cartridge holder mounted in the housing and configured to receive a cartridge containing a medicament, an injection needle having a proximal end and a distal end, an injection needle holder to which the injection needle is fixed. The medicament injection device comprises an actuating mechanism for pivoting the injection needle holder relative to the cartridge holder between a storage position in which, when the cartridge is received in the cartridge holder, the distal end of the injection needle is spaced from the cartridge, and a use position in which, when the cartridge is received in the cartridge holder, the distal end of the injection needle can engage the cartridge.

Abstract: A dosing device includes a rod element and a shell. The rod element has a stem with a longitudinal axis and a first thread arrangement. The shell has a second thread arrangement. The first thread arrangement of the rod element or the second thread arrangement of the shell includes a thread. The first thread arrangement of the rod element and the second thread arrangement of the shell engage. The rod element is movable along the longitudinal axis of its stem by rotating the shell and the rod element relative to each other causing the first thread arrangement of the rod element and the second thread arrangement of the shell to travel along each other. A dosage chamber is formed by moving the rod element along the longitudinal axis of its stem. The volume of the dosage chamber is varied by moving the rod element along the longitudinal axis of its stem. An inclination angle (?, ?) of the thread varies along the thread.

Abstract: Kits carrying various components and devices are provided for use in obtaining access to a patient's vascular system. Various methods and procedures may be used to treat both emergency and more routine conditions using the contents of such kits. For example, such kits may contain various types of intraosseous (IO) devices including, but not limited to, drivers, penetrator assemblies, IO needles and other related components. Intravenous (IV) devices such as syringes, needles, IV bags, tubing and other related components for use in obtaining access to portions of a patient's vascular system may be included. Various types of connectors for communicating fluids with and/or monitoring a patient's vascular system may be provided. Such kits may contain medications, drugs and fluids used to treat a wide variety of both acute and chronic diseases and conditions.

Abstract: The disclosure relates to a drug delivery device for dispensing a liquid drug through a needle with a proximal and a distal needle tip, comprising a body, a needle holder holding the needle relative to the body, a cartridge holder holding a cartridge comprising the liquid drug sealed with a septum on a distal end and with a movable stopper on a proximal end, and a cap adapted to cover at least the distal needle tip of the needle, wherein the cartridge holder is movable relative to the body from a retracted position towards an advanced position, thereby piercing the proximal needle tipthrough the septum, characterized in that the cap is releasably engaged with the cartridge holder, wherein the cap is released from the cartridge holder in its advanced position.

Abstract: Described is an actuation mechanism for a medicament delivery device having a needle with a distal tip. The actuation mechanism comprises an outer sleeve telescopically relative to the delivery device and an inner sleeve telescopically arranged relative to the outer sleeve. The outer sleeve is axially translatable relative to the delivery device, and the inner sleeve is axially translatable relative to the outer sleeve. In a first state, the inner sleeve protrudes distally from the outer sleeve and the outer sleeve protrudes distally from the delivery device. In a second state, the inner sleeve is contained within the outer sleeve. Movement of the outer sleeve proximally relative to the delivery device in the second state initiates delivery of a medicament in the delivery device.

Abstract: A medicament delivery device is presented having a housing that is arranged to accommodate a medicament container, a drive unit operably arranged to act on the medicament container upon activation, an activation mechanism operably arranged to be operated by a user, an activation preventing mechanism operably arranged to prevent the activation mechanism to be activated, an usage management module arranged to be operated by a user, which usage management module is designed as an attachable unit to the medicament delivery device. First keying elements are arranged on the device and on the usage management module designed to interact with each other when attaching said usage management module, such as to cause a deactivation of the activation preventing mechanism to allow operation of the activation mechanism. The usage management module can include a monitoring circuit arranged to monitor the use of the medicament delivery device.

Abstract: A needle insertion and retraction mechanism for a drug delivery device, comprises a motion source, a user-operated control for the motion source, an interrupter for stopping motion of the motion source at a predetermined location and thereby dividing the motion into two parts which are continuous relative to each other. A motion translation mechanism connects the source of continuous motion to a needle, to extend the needle during the first motion part and to retract the needle during the second motion part. The needle is thus extended and retracted by continued operation of a single tension source rather than two tension sources operating in opposition to each other. The motion source may be a spring, and a winding mechanism may be provided to wind the spring. The second motion part may be initiated by pulling the adhered delivery device from the skin.

Abstract: An injection device for the delivery of medicament has an indicator for providing an activation indication. The device includes a housing; a plunger slidably mounted within the housing; an actuation mechanism configured, in use, to move the plunger forward relative to a syringe so as to express medicament from the syringe. The device also includes an indicator element responsive to the forward movement of the plunger and configured to provide an audible and/or tactile and/or visual indication when the plunger reaches or approaches its forward position. The plunger includes an elongate shaft formed of at least two telescopic sections. The actuation mechanism acts on the plunger, in use, to expand the telescopic sections and to sequentially move each of the telescopic sections forwardly within the housing. The indicator element is arranged to be responsive to the forward movement of the trailing telescopic section.

Abstract: A method provides for procuring platelet rich plasma (PRP) from a sample of whole blood in a vial. The method includes the steps of: separating the whole blood into layers through centrifugation with an upper layer containing platelet poor plasma (PPP) and a PRP layer below the upper layer containing PRP; adjusting an end point of a first range of motion of an extractor relative to a position of the PRP layer; moving the extractor through the first range of motion through the vial, PPP passing out from the upper layer through the extractor; and after the extractor reaches the end point of the first range of motion, extracting the PRP through the extractor and collecting the PRP.

Abstract: A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The cassette may further have a sleeve movably disposed within the housing, for holding a drug container, and a locking arrangement for interlocking the sleeve with the housing. The cassette may further have an aperture in the housing, and a cassette cap for removing a needle shield of the drug container. The cassette may have an anti-bending structure to prevent bending or flexing of the cassette cap. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detecting and communicating the cassette ID to the microprocessor to decipher the code defined therein. Also, a method of injecting a drug into a patient with an injector, wherein the sequence of actions performed by the user are controlled.

Abstract: An administration instrument includes an injection button which can be pressed at an angle that is not parallel to a needle with respect to a direction in which the needle is inserted into skin. As a result, it is possible to prevent a force of pressing the injection button from being transmitted in the direction in which the needle is inserted into the skin deeper than initial insertion of the needle, thereby achieving an administration under a stable state.

Abstract: Embodiments of a syringe-based device for delivering fluid include a housing, a port, the port being positioned at about the distal end of the housing, a plunger assembly, the plunger assembly including, a plunger seal, a valve, and a cannula, a first fluid reservoir, where the first fluid reservoir retains a first type of fluid, a syringe including a syringe body, a syringe port, a plunger, and a second fluid reservoir, the second fluid retaining a second type of fluid, and where the syringe transitions from a first configuration in which a first portion of the first fluid type is delivered through the port, to a second configuration in which the second type of fluid in the second fluid reservoir is delivered through the port, to a third configuration in which a second portion of the first fluid type is delivered through the port.

Abstract: An assembly for a drug delivery device includes an actuator configured to perform a setting movement in order to set a dose of medication and to perform a dispense movement in order to dispense a dose of medication. The assembly further includes a stop mechanism which is configured to allow a setting movement of the actuator after a maximum amount of medication has been delivered and to inhibit a dispense movement of the actuator after a setting movement when a maximum amount of a medication has been delivered.

Abstract: An injector for delivering a medicament includes an outer sleeve, an inner sleeve, and a syringe. The inner sleeve is disposed partially within the outer sleeve. A plunger rod of the syringe is engaged with the outer sleeve in a fixed spatial relationship such that the plunger rod and the outer sleeve translate as a unit. The outer sleeve is configured for axial translation relative to the inner sleeve from a first configuration wherein the inner sleeve extends from the outer sleeve a first distance to a second configuration in which the inner sleeve extends from the outer sleeve a second distance that is less than the first distance. Further, in a third configuration the inner sleeve extends from the outer sleeve a third distance that is greater than the second distance and the inner sleeve is restricted from axially translating with respect to the outer sleeve.

Abstract: The priming configuration comprises a piston rod (1), a bung (2), which is provided to be driven by the piston rod, and a movable element (5), which is engaged with the piston rod. The movable element is arranged to be movable in a predefined direction (10) with respect to the piston rod by a user of the drug delivery device. A movement of the movable element in the predefined direction advances the piston rod in a further direction (11), providing a priming of the drug delivery device before use. The predefined direction may especially be transverse to the further direction, and the further direction may especially be directed from the piston rod towards the bung (2). A gap (12) or clearance between the piston rod (1) and the bung (2) can thus be removed, and the stiction of the bung (2) to the cartridge (3) can be reduced.

Abstract: The present invention relates to a medicament delivery device comprising a drive means configured to act on a medicament container for expelling a medicament; a holding means configured to hold said drive means in a pre-tensioned state; an activation means configured to interact with said holding means for releasing said drive means from the pre-tensioned state; wherein the device further comprises feedback means configured to interact both with said holding means and with said drive means for generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.

Abstract: Systems and methods for delivering microneedles to a patient's skin are described. In one aspect, a system for delivering a microneedle array to a patient's skin surface is provided. The system includes a delivery apparatus with a housing, and an infusion device detachably received in the housing.

Abstract: Multicomponent infusion device assemblies include locking and unlocking mechanisms that allow for locking and unlocking of components via actions capable of being carried out by at least some patients suffering from movement disorders. Tools or disengagement components may be used to unlock or disengage the components.

Abstract: Kits carrying various components and devices are provided for use in obtaining access to a patient's vascular system. Various methods and procedures may be used to treat both emergency and more routine conditions using the contents of such kits. For example, such kits may contain various types of intraosseous (IO) devices including, but not limited to, drivers, penetrator assemblies, IO needles and other related components. Intravenous (IV) devices such as syringes, needles, IV bags, tubing and other related components for use in obtaining access to portions of a patient's vascular system may be included. Various types of connectors for communicating fluids with and/or monitoring a patient's vascular system may be provided. Such kits may contain medications, drugs and fluids used to treat a wide variety of both acute and chronic diseases and conditions.

Abstract: An injectable substance delivery device comprising a pen device body, a cartridge, a plunger, a drive mechanism, and at least one of a lock-out mechanism and a rate-limiting mechanism. The lock-out mechanism is provided through a ratchet engagement between the body and the plunger to restrict plunger movement and to ensure that the required needle puncture depth is realized prior to injection by locking out the injection mechanism from advancing until a specified force is applied to the skin. A rate-limiting mechanism is also provided through a user compressed plunger drive spring to ensure that a specific rate of injection is realized during the injection of a medicament.

Abstract: The invention refers to a shuttering mechanism for controlling translation of a longitudinally moveable component within an elongate housing, the shuttering mechanism comprising at least one set of castellations on the housing and at least one resilient arm associated with the longitudinally moveable component, the resilient arm having a dog resiliently biased towards the castellations so as to engage between or behind the castellations and block the translation, wherein a respective shutter arm is arranged alongside the set of castellations, the shutter arm having a number of consecutive ramped protrusions spaced from each other, wherein the castellations and the ramped protrusions have the same pitch, wherein a profiled surface is formed by the castellations and the ramped protrusions, wherein the shutter arm is moveable in longitudinal direction with respect to the set of castellations, wherein the shutter arm has at least one locking position with its ramped protrusions essentially in phase with the caste

Abstract: The present invention relates to a medicament delivery device comprising a drive means configured to act on a medicament container for expelling a medicament; a holding means configured to hold said drive means in a pre-tensioned state; an activation means configured to interact with said holding means for releasing said drive means from the pre-tensioned state; wherein the device further comprises feedback means configured to interact both with said holding means and with said drive means for generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.

Abstract: The present invention relates to a medicament delivery device. The medicament delivery device may include an operation member configured to act on a medicament container for expelling a medicament. The device may be configured to hold the operation member in a pre-tensioned state. The device may include an activation member configured to interact with the operation member to release it from the pre-tensioned state. The device may further comprise feedback. For example, the feedback may include generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.

Abstract: An injection device including a housing, a needle guard sleeve displaceable relative to the housing, and a spring coupled to the guard sleeve such that the guard sleeve can be moved by the spring distally from a proximal position to an end position, the spring also being coupled to a forward drive element displaceable relative to the housing in a drive direction wherein the spring is tensioned upon a movement of the forward drive element in the forward drive direction.

Abstract: A lancet device including a housing and a lancet structure having a puncturing element. The lancet structure disposed within the housing and adapted for movement between a retaining or pre-actuated position wherein the puncturing element is retained within the housing, and a puncturing position wherein the puncturing element extends through a forward end of the housing. The lancet device includes a drive spring disposed within the housing for biasing the lancet structure toward the puncturing position, and a retaining hub retaining the lancet structure in the retracted position against the bias of the drive spring. The retaining hub includes a pivotal lever in interference engagement with the lancet structure. An actuator within the housing pivots the lever, thereby moving the lancet structure toward the rearward end of the housing to at least partially compress the drive spring, and releasing the lever from interference engagement with the lancet structure.

Abstract: A two-dose autoinjector for a medicament wherein the locking and releasing of the drive spring of the autoinjector is controlled through stepped guides with ramps for two successive slidings of slides operated by the spring and connected with the syringe and plunger. The guides and the slides are pivotable relative to one another and the sliding direction, while the syringe can only slide axially. To enable or disable the sliding of the slides within the guides an angularly angularly mobile arming member is provided formed with a guide track substantially equal to that of the stationary member where the guides are formed.

Abstract: An auto-injector comprising a housing arranged to contain a slidably arranged syringe. The housing having a distal end and a proximal end with an orifice. Spring means is capable of, upon activation: pushing the needle into an advanced position and into an injection site, operating the syringe to inject a dose of medicament, and retracting the syringe. Activating means locks the spring means in a pressurized state prior to manual operation and capable of releasing the spring means for injection. The spring means is a compression spring grounded distally in the housing and proximally bearing against a thrust tube arranged to transmit load from the spring means via a plunger to the syringe and/or the stopper. A tubular syringe carrier is arranged for holding the syringe and supporting it at a proximal end, the syringe and the syringe carrier arranged for joint axial translation.

Abstract: An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal.

Abstract: A lancet device including a housing and a lancet structure having a puncturing element. The lancet structure disposed within the housing and adapted for movement between a retaining or pre-actuated position wherein the puncturing element is retained within the housing, and a puncturing position wherein the puncturing element extends through a forward end of the housing. The lancet device includes a drive spring disposed within the housing for biasing the lancet structure toward the puncturing position, and a retaining hub retaining the lancet structure in the retracted position against the bias of the drive spring. The retaining hub includes a pivotal lever in interference engagement with the lancet structure. An actuator within the housing pivots the lever, thereby moving the lancet structure toward the rearward end of the housing to at least partially compress the drive spring, and releasing the lever from interference engagement with the lancet structure.

Abstract: A device for the automatic injection of doses of a drug is described. The device has a slide and cam means, a syringe unit with a piston, and guide means. The axial movement of the slide initiated by a user by depressing its front end against an injection site, causes an angular displacement of the cam means that, in cooperation with the guide means, controls movement of the syringe piston and therefore administration of a drug dose.

Abstract: An insertion device for applying an infusion set to the body of a patient, wherein the device has two actuation members which have to be actuated simultaneously to trigger an insertion movement by which a cannula of the infusion set is introduced into the body and wherein, in some embodiments, one of the actuation members is a securing slide including a contact face to be placed on the body of the patient, the securing slide being actuated by the insertion device being pressed, via the contact face, against the body of the patient.

Abstract: The present invention relates to a medicament delivery device comprising a drive means configured to act on a medicament container for expelling a medicament; a holding means configured to hold said drive means in a pre-tensioned state; an activation means configured to interact with said holding means for releasing said drive means from the pre-tensioned state; wherein the device further comprises feedback means configured to interact both with said holding means and with said drive means for generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.

Abstract: A key-shaped portable injector for delivering a dose of medication, the injector preferably including a cap, a body having an internal cavity, a syringe or cartridge with an attached needle within the internal cavity, a protective sleeve, an activation mechanism and a safety mechanism wherein the injector is reconfigurable from a first, non-deployed configuration where the activation mechanism, syringe or cartridge and a safety mechanism are all in a first position with respect to the body to a second, deployed configuration where the safety mechanism, activation mechanism, and syringe or cartridge are all in a second position with respect to the body and to a third, depleted configuration where the activation mechanism is back to its first position and a protective sleeve is in its second position.

Abstract: Devices and methods for guidewire assisted placement of catheters into blood vessels are described. Some of the devices and methods relate to automated or partially automated or assisted insertion and placement of an intravenous catheter into a vein or artery of a patient. Other of the devices are blood draw devices and methods for insertion and placement of an intravenous device into a vein or artery of a patient or to withdraw a blood sample from the patient. The devices also provide for guide wire tip inspection after use.

Abstract: An injection device is provided. The device includes a housing having a first end defining a first opening. A plunger is received within the first opening of the housing to move between first and second positions. A cartridge is disposed in the housing and has an interior serving as a reservoir for a drug. A delivery needle is disposed within the housing and is in fluid communication with the reservoir via an interruptible fluid channel. A locking mechanism is disposed in the housing. In the first position of the plunger the delivery needle is enclosed by the plunger and in the second position of the plunger the delivery needle is placed in an injection position and the plunger activates the locking mechanism whereby when the plunger returns to the first position the locking mechanism prevents the needle from being placed in the injection position.

Abstract: The invention relates to an injection device comprising a housing, a container holder arranged within said housing, the container holder being configured for accommodating a medicament container having a needle attached to one end thereof and a stopper sealingly and slidable arranged inside the medicament container at the other end thereof, a drive unit comprising a plunger rod and plunger drive means, the plunger drive means being slidable arranged in relation to the plunger rod, being rotationally locked to the plunger rod and being rotatable in relation to the housing, said drive unit further comprising a first energy accumulating member arranged in the interior of the housing of the injection device and adapted to accumulate and store energy, wherein said plunger drive means is operationally associated with said first energy accumulating member, wherein the plunger drive means is releasable such that due to an output torque from said first energy accumulating member, the plunger drive means are allowed to