Abstract: A device for aseptic delivery of biological material from a vial includes a tubular barrel, a filter assembly, and a dispersion assembly. The dispersion assembly is at least partially disposed within the tubular barrel. The dispersion assembly includes a dispersion element, a piston, and a one-way valve. The dispersion element is in fluid communication with the vial to disperse the biological material from the vial. The piston is disposed at the distal end of the dispersion assembly and is in sealing contact with the tubular barrel. The one-way valve forms a fluid passageway in fluid communication with the dispersion element and the tubular barrel. The one-way valve is configured to allow a flow of the dispersed biological material from the dispersion element, through the fluid passageway, and into the tubular barrel, and to prevent a flow of the dispersed biological material from the tubular barrel into the dispersion assembly.

Abstract: The present disclosure relates to relates to medication injection devices, and in particular to systems and methods for on-demand delivery of a non-liquid medication from a wearable medication injection device. Particularly, aspects of the present invention are directed to a device that includes a housing defining a chamber, a piston disposed within the chamber, a needle disposed within the chamber on a first side of the piston, an energetic material disposed within the chamber on a second side of the piston, and a medication strip disposed within the needle. The medication strip includes an injectable substance in a non-liquid form.

Abstract: Disclosed herein is an injection device with housing that defines a channel and a first injection guide opening. The first injection guide opening enters the channel in a manner that allows a needle to penetrate a vessel in an animal with accuracy and at the same time protect the user from the needle.

Abstract: A method and system for detecting a limit of use of a medical device is disclosed. The method includes starting a timer of a medical device when the medical device is used for the first time, detecting the limit of use of the medical device and indicating the limit of use of the medical device. The limit of use is reached when at least one of a first criterion and a second criterion is met, wherein the first criterion is that the timer reaches or exceeds a time limit and wherein the second criterion is that at least one operation of a drive train of said medical device reaches or exceeds a limit.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: An automatic medication dispenser with electronic thermometer. The automatic medication dispenser provides for the delivery of medication to a user upon detection of a body temperature above a predetermined amount. A housing can receive a cartridge having medication and dispense the medication through a valve, a tubular member, and a mouthpiece. An electronic thermometer detects the body temperature and also displays the body temperature on the housing. The body temperature determines if the valve allows for a dose of the medication to be administered.

Abstract: A drug delivery device (100) for administering a low dose of a medicament includes a housing (111) and a drug reservoir (101) disposed in the housing (111). A needle (135) is connected to the drug reservoir (101). A pressure applying member (113) is movably connected to the housing (111) and is movable between first and second positions. The pressure applying member (113) does not apply pressure to the drug reservoir (101) in the first position and applies pressure to the drug reservoir (101) in the second position to dispense medicament stored in the drug reservoir (101). A method of administering a low dose of insulin to simulate a first-phase insulin response of a pancreas is also disclosed.

Abstract: A method for detecting a limit of use of a medical device is presented having the steps of starting a timer of a medical device when the medical device is used for the first time, detecting the limit of use of the medical device and indicating the limit of use of the medical device. The limit of use is reached when at least one of a first criterion and a second criterion is met, wherein the first criterion is that the timer reaches or exceeds a time limit and wherein the second criterion is that at least one operation of a drive train of said medical device reaches or exceeds a limit.

Abstract: Apparatuses for automatic medicament injection and methods for manufacturing automatic medicament injectors are described herein. In some embodiments, an apparatus includes a housing, a needle, an energy storage member, an actuator, a locking member, and a needle guard. The needle is configured to move between a first position and a second position. In its first position, the needle is contained within the housing. In its second position, at least a portion of the needle extends from the housing. The energy storage member has a first configuration and a second configuration and is configured to produce a force when moving between its first configuration and its second configuration to move the needle from its first position to its second position. The actuator is configured to move the energy storage member from its first configuration to its second configuration.

Abstract: A delivery probe for delivering a therapeutic agent to tissue is described including at least one delivery capsule for accommodating the agent, at least one delivery device in fluid communication with the capsule, an actuation mechanism for moving the capsule between an activated position and an inactivated position by providing at least one of a fluid and a vacuum, and a delivery mechanism for forcing the agent out of the capsule. A method of delivering a therapeutic agent to tissue is also described including providing a catheter with a delivery probe at a distal end, positioning the delivery probe next to the tissue, supplying fluid to an actuation chamber to position the probe into an activated position, supplying fluid to a delivery chamber to force the agent out of the probe, and establishing a vacuum in the actuation chamber to position the probe into an inactivated position.

Abstract: A syringe includes a sleeve and a pressure vessel with high pressure fluid therein. The sleeve further comprises a sleeve piston. As the high pressure vessel contacts the sleeve piston, and a bump on the sleeve piston destroys the airtight status of the high pressure vessel. While the seal of the high pressure vessel is removed, the compressed fluid flows into the sleeve through the opening of the high pressure vessel and the hole of the sleeve piston. When the closed end of the sleeve moves closer to the closed end of the sleeve piston, the fluid in the sleeve is pressed and flows out of the sleeve through the sleeve hole of the sleeve.

Abstract: An apparatus includes a housing, a medicament container, an actuator, and a biasing member. The actuator is configured to move the medicament container within the housing when the actuator is moved from a first configuration to a second configuration. The actuator includes a gas container and a puncturer. When the actuator is in the first configuration, a portion of the puncturer is disposed apart from the gas container. When the actuator is in the second configuration, the portion of the puncturer is disposed within the gas container. The gas container has a longitudinal axis offset from a longitudinal axis of the medicament container. The biasing member is configured to bias the actuator toward the second configuration.

Abstract: A device for inserting at least one hollow needle for the injection or withdrawal of a solution into/from a tissue, said device comprising a casing (1), a plunger (2) movably mounted inside the casing, and propulsion means (3 and 4) suitable for driving the plunger towards the distal end (1a) of the device by applying a force F1(t). The propulsion means and/or the plunger comprise retaining means (3a) for joining the propulsion means and the plunger while the latter is moving, said retaining means releasing the plunger from the propulsion means when a force F2(t) is exerted in the opposite direction to F1(t). Pressure means hold the needle in the tissue and allow a controlled withdrawal of the plunger at least while the solution is being injected.

Abstract: A method of treating a prostate condition, including the steps of providing a needleless injector that includes a body at a proximal end, an injection shaft extending from the body to a distal end of the injection shaft, an injection orifice at the distal end of the injection shaft and positioned for fluid ejection in a lateral direction relative to a longitudinal axis of the injection shaft, a pressure source in communication with the fluid chamber, and an extendable tissue tensioner located at the distal end of the injection shaft proximal to the injection orifice; inserting the injection shaft into a urethra so the injection orifice is located within the prostatic urethra; actuating the tissue tensioner to contact urethral tissue, and injecting fluid from the injection orifice into the prostate.

Abstract: A needleless injector including a body including a fluid chamber; an outer shaft extending from an outer shaft proximal end to an outer shaft distal end, wherein the outer shaft includes an outer shaft lumen to accommodate an injection shaft; an injection shaft located within the outer shaft lumen and moveable lengthwise and/or rotationally within the outer shaft lumen, wherein the injection shaft includes an injection shaft proximal end, an injection shaft distal end, an injection shaft terminus, and an injection lumen. The injector further includes an injection orifice at the distal end of the injection shaft and in fluid communication with the fluid chamber through the injection lumen; a pressure source in communication with the fluid chamber; and an optical device that allows viewing a location at a distal end of the device.

Abstract: An injection device comprising an outer housing adapted to receive a syringe for holding a volume of a medicament, said syringe comprising a barrel, a needle at one end of the barrel, and a plunger, axially moveable within the barrel, the needle and barrel being such that at least part of the needle is axially moveable in and out of said outer housing but is biased to be normally wholly inside said housing. The injection device further comprises an inner housing intermediate the outer housing and at least part of the barrel and/or plunger, an energy source in communication with the inner housing, and blocking means capable of preventing said inner housing moving axially under the influence of said energy source.

Abstract: A device releases a fluid active substance, the device has at least one hollow space containing the fluid active substance, whereby the device contains water and a reducing agent, which are or can be made to be in communication such that a chemical reaction of the water and the reducing agent produces a gas and the gas effectively communicates with the fluid active substance such that the gas pressure thus generated presses the fluid active substance out of at least one opening of the hollow space out of the device. A medical implant incorporates the device, and a method releases a fluid active substance from a hollow space of the medical implant, in which a gas is produced through a chemical reaction of liquid water and a reducing agent, and the resulting gas pressure is used to expel the fluid active substance out of at least one opening of the hollow space.

Abstract: A surgical device comprises a housing, a plurality of media reservoirs, an end effector, and a pumping device. Each media reservoir is configured to receive at least one component of a tissue repair composition. The end effector is configured for insertion into a lumen to deliver a tissue repair composition into that lumen. The end effector has at least one fluid conduit and at least one orifice in communication with the fluid conduit. The pumping device is operable to urge a tissue repair composition comprising at least a portion of the contents of the plurality of media reservoirs through the fluid conduit of the end effector such that the tissue repair composition is expelled from the at least one orifice. The media reservoirs may contain medical fluid components such as viable cells and scaffold material to repair a fistula or address some other condition in a patient.

Abstract: An apparatus includes a movable member and a valve coupled to the movable member. The movable member is configured to be disposed within a housing of a medical device and has a first end portion and second end portion. A portion of the first end portion is configured to define a portion of a boundary of a gas chamber. The first end portion defines an opening configured to be in fluid communication between the gas chamber and an area outside the gas chamber. The second end portion is configured to be coupled to a needle configured to deliver a medicament into a body. The valve is configured to selectively allow fluid communication between the gas chamber and the area outside the gas chamber through the opening defined by the first end portion of the movable member.

Abstract: Remote controls, including a communication device, a button or other communication device actuator and a movable structure that allows actuation of the actuator in one position and prevents actuation of the actuator in another position to prevent inadvertent signal transmission.

Abstract: This document discloses, among other things, an air-powered auto-injector device for subcutaneous delivery of a rescue drug. The device is configured for self-administered treatment of anaphylactic shock. Air is compressed by relative movement of a piston and a cylinder and released to subcutaneously drive an hypodermic needle.

Abstract: An anti-hemorrhage medication pack for administering an anti-hemorrhage drug, in particular for the treatment of hemorrhage caused by trauma in emergency situations comprises an active ingredient selected from the group comprising the 1-24 amino acid sequence of the adrenocorticotropic hormone (ACTH 1-24) and all its fragments and analogues, and analogues of fragments, with agonist activity on the MC4 melanocortin receptors, and all the synthesis agonists, including those with a nonpeptidic structure, of the MC4 melanocortin receptors. An auto-injector (1; 11) includes the drug for automatically injecting a patient with the drug.

Abstract: Described are devices and methods related to the needleless injection of fluid into tissue of the lower urinary tract, such as the urethra and prostate.

Abstract: An injection device that comprises a chamber configured for containing a substance to be injected and a needle operatively associated with the chamber and having a length sufficient to deliver the substance to an intradermal injection site. A collar surrounds the needle, defining a collar cavity. The collar also has a peripheral forward skin-contacting surface that surrounds and is radially spaced from the needle and injection site by an area that is sufficiently large to allow a patient's skin to move into the collar cavity to properly position the needle for intradermal delivery of the substance to the injection site to allow spread of the injected substance under the skin while inhibiting or preventing backpressure within the skin from forcing the substance out through the injection site.

Abstract: The invention relates to a device for injecting veterinary products to at least one bird by intramuscular injection, wherein said injection(s) can be carried out in the area of at least one muscle in the vicinity of a bone having a detectable shape in the body of said poultry, said device comprising: a retention member with means for bracing said detectable bone, at least one hole being formed in said retention member; at least one injection needle, said needle(s) being movable across said opening(s); characterized in that the retention member has: an anatomic shape that conforms to a portion of the body of said poultry and inside which is provided said means or bracing the detectable bone, said anatomic shape including a bearing surface for said body at said muscle; at least two contact sensors to be actuated by said poultry and provided on the anatomic shape with at least one on the bearing surface, said opening(s) being provided between said sensors.

Abstract: An injection device comprising an outer housing adapted to receive a syringe for holding a volume of a medicament, said syringe comprising a barrel, a needle at one end of the barrel, and a plunger, axially moveable within the barrel, the needle and barrel being such that at least part of the needle is axially moveable in and out of said outer housing but is biased to be normally wholly inside said housing. The injection device further comprises an inner housing intermediate the outer housing and at least part of the barrel and/or plunger, an energy source in communication with the inner housing, and blocking means capable of preventing said inner housing moving axially under the influence of said energy source.

Abstract: The present invention relates to medical devices and particularly to a medication delivery device for self-injection of a medication, or for healthcare professionals to administer a medication. In one embodiment, a medication delivery device utilizes a source of gas pressure to deploy a needle, deliver a desired amount of medication through the needle, and retract the needle for disposal. Fluid flow paths from the source of gas pressure communicate the gas pressure to the needle and to the medication in order to accomplish these steps. In one embodiment, a valve is positioned to open and close the flow of the pressurized gas to the needle and the flow of the medication to the needle, so that the valve can be operated to deploy the needle and deliver the medication through the needle when the user is ready for the injection. The valve can also be operated to retract the needle when the dose is complete.

Abstract: An apparatus includes a movable member and a valve coupled to the movable member. The movable member is configured to be disposed within a housing of a medical device and has a first end portion and second end portion. A portion of the first end portion is configured to define a portion of a boundary of a gas chamber. The first end portion defines an opening configured to be in fluid communication between the gas chamber and an area outside the gas chamber. The second end portion is configured to be coupled to a needle configured to deliver a medicament into a body. The valve is configured to selectively allow fluid communication between the gas chamber and the area outside the gas chamber through the opening defined by the first end portion of the movable member.

Abstract: An apparatus includes a movable member and a valve coupled to the movable member. The movable member is configured to be disposed within a housing of a medical device and has a first end portion and second end portion. A portion of the first end portion is configured to define a portion of a boundary of a gas chamber. The first end portion defines an opening configured to be in fluid communication between the gas chamber and an area outside the gas chamber. The second end portion is configured to be coupled to a needle configured to deliver a medicament into a body. The valve is configured to selectively allow fluid communication between the gas chamber and the area outside the gas chamber through the opening defined by the first end portion of the movable member.

Abstract: The apparatus for deployment of an intravascular therapeutic device, includes an elongated, flexible pusher member and a therapeutic device connected to a severable portion of a first connector member mounted to the flexible pusher member with an elongated second connector member connected to the therapeutic device. The first connector member or second connector member may be capable of being broken by heat, and a heat source is provided for heating and breaking the first connector member or the second connector member to release the therapeutic device.

Abstract: An injection device comprising an outer housing inside which is located a medicament-holding barrel with a needle at one end thereof, at least part of the needle being moveable in and out of the outer housing, a plunger moveable within the barrel, an inner housing intermediate the outer housing and the barrel and plunger and an energy source in communication with said inner housing. The inner housing is moveable by the energy source between a first position in which the plunger and barrel are movable axially so as to move at least part of said needle out of the outer housing; a second position in which the plunger is movable axially into said barrel so as to expel medicament through the needle; and a third position in which the plunger and barrel are able to retract in order to retract the needle into the outer housing.

Abstract: Medical injectors are described herein. In some embodiments, an apparatus includes a medicament container, a needle assembly, a coupler, and a retainer. The medicament container has a distal end and a proximal end and is configured to contain a medicament. The coupler is configured to couple the needle assembly, which includes a needle and a hub, to the distal end of the medicament container. The retainer is configured to be coupled to the needle assembly and the medicament container. The retainer is configured to limit the movement of the needle assembly when the coupler fails to maintain the position of the needle assembly relative to the distal end of the medicament container.

Abstract: Certain exemplary embodiments comprise an apparatus, comprising: a compressed gas container; a plurality of vials adapted to store a liquid medicament, each vial defining a longitudinal axis, the longitudinal axes of the plurality of vials parallel and non-co-axial, the plurality of vials fluidly coupleable to an actuating portion of a contents of the gas container; and a plurality of pistons, each piston adapted to move within a corresponding vial from the plurality of vials, the plurality of pistons adapted to, in response to discharge of the actuating portion of the contents of the compressed gas container, transfer at least a portion of the liquid medicament from the plurality of vials and through a needle that is extendable into a patient.

Abstract: The delivery of a fluid cutaneously is effected by generating a suction force on a surface of a housing. A surface of a cutaneous layer is received under the suction force about which the proximal end of a needle thereby to pierce the cutaneous surface and to effect an injection of fluid. There is generated a suction force to operate the movement of a needle in the housing. The needle is moved under the suction force from the housing thereby to permit piercing a cutaneous layer. The bladder for containing fluid is emptied under the suction into the distal end of the needle and thereby permit the expulsion of fluid through the proximal end of the needle for injection below the cutaneous layer.

Abstract: The present invention provides systems for the injection delivery of at least two fluid doses to a small bird by penetrating the skin of the recipient bird with at least two injection needles. It is then possible to simultaneously inject drugs, or other fluid vaccines that do not mix well or whose mixture would be detrimental to the stability or efficacy of the active ingredients therein. The present invention provides a novel injection needle support for connecting the injection needles to dose distributors and fluid supply containers while maintaining the injection ends of the injection needles in a substantially parallel arrangement. The injection needle support typically is attached to a carrier connected to an actuator, an actuator power source and a switch mechanism wherein the actuator, when activated, can reciprocally move the carrier and injection support toward and away from an injection position.

Abstract: An inoculation device and method are provided. The device includes a hypodermic syringe with a hollow needle that is positioned to inject a small animal in its abdominal area with an inoculant. A work platform supports the animal during inoculation in a back down, face up orientation. Air flow sensing activation mechanism is positioned adjacent a portion of the animal. When the animal is moved into contact with the activation mechanism, drive connected to the hypodermic syringe moves the needle forward to penetrate the animal after which the inoculant is injected.

Abstract: System for delivering an implant to tissue to be treated which includes a housing, a delivery head which carries the implant and is movable between extended and retracted positions relative to the housing, an actuator mounted in the housing and connected to the delivery head for moving the delivery head from the retracted position to the extended position and back to the retracted position, and a depth gauge mounted to the housing for determining how far the implant is inserted into the tissue when the delivery head is moved to the extended position.

Abstract: A method of ligating anatomical tissue using a suture spring device of coiled configuration includes expanding the suture spring device from a relaxed, unexpanded state to an elastically deformed, expanded state, positioning the anatomical tissue in an axial space between rings or coils of the suture spring device when the device is in the elastically deformed, expanded state, and allowing the suture spring device to contract from the expanded state toward the unexpanded state to ligate the anatomical tissue. The rings or coils of the suture spring device can be axially and/or radially expanded in the elastically deformed, expanded state. In the case of the rings being radially expanded, the anatomical tissue is preferably repositioned to be disposed concentrically within a central longitudinal passage or aperture of the suture spring device so that the rings are coiled around the anatomical tissue in the expanded state and able to apply a radially compressive force when contracted.

Abstract: Transfusion and perfusion device having two pressure bags communicating via a calibrated pressure-reducing valve, each pressure bag including an inflatable pressure balloon. Each balloon is held in an envelope and has the same shape as its envelope. An inflating device provides for the inflation of the pressure balloon, and a verticalization device ensures verticality of the drip. Both envelopes which hold the two balloons are flexible and are each provided with a sleeve intended to receive a flexible pouch of the perfusion product in such a way that the pressure balloon contained in its envelope may be inflated to a high pressure and therefore may act as a pressing balloon in order to provide the flow rate necessary for life support. The invention is applicable to the medical and veterinary fields.

Abstract: Charges of solid coolant granules are automatically inserted into a fresh animal carcass or a portion of an animal carcass by the use of an inserting tool. The granular solid coolant charge is contained within a chamber of the tool which also includes a flat spear blade. When the blade forms a slit in a selected muscle area, the granular solid coolant charge is positively, rapidly and consistently positioned within the pocket that had just been opened by the spear blade. The insertion tool and process are especially well-adapted for use in reducing the development of pale, soft and exudative meat, while accomplishing this in a manner that is rapid and minimizes variations from carcass to carcass.

Abstract: A method for the delivery of medicaments to newly hatched poultry. A vaccine or other medicament is injected into the yolk sac of a newly hatched chick, and is released to the chick's system as the yolk is absorbed by the chick. An injection device is shown having one or optionally a pair of guide services for guiding a chick axially of a hypodermic needle during an injection procedure to reduce damage to the injection site.

Abstract: A modular poultry automatic injection and spraying apparatus (10) featuring a dual-sensor switch means (41) and a dual-action, fluid-actuated drive means (101) is disclosed. The apparatus has a casing construction (11) including an upper housing (12) mounted on a lower housing (13) such that the lower housing (13), which contains water-sensitive pneumatic logic circuitry (261), can be easily removed prior to cleaning. The casing construction (11) has the additional advantage of allowing substitute upper and lower housings (12, 13) to be interchanged during maintenance and repair. The dual sensor switch means (41) ensures that the injections are performed accurately and consistently. The dual-action, fluid-actuated drive means (101) allows for the simultaneous injection and spraying functions of the apparatus (10) obviating the need for an additional apparatus or separate compressed air signal.

Abstract: Apparatus for typically delivering a measured quantity of liquid to a small animal comprising:a spray nozzle for producing an atomized stream of liquid;a syringe in fluid communication with the spray nozzle for delivering a measured quantity of the liquid from a liquid source to the spray nozzle;means for actuating the syringe to deliver the measured quantity of liquid activated by a compressed air signal from a compressed air source;means for regulating the compressed air signal to deliver to the spray nozzle a portion of the compressed air signal for atomizing the measured quantity of liquid; andmeans for transmitting the compressed air signal simultaneously to the actuating means and to the regulating means.

Abstract: A bird is positively positioned in a fixed cradle and a motor drives injection needles at convergent angles into the bird's breast muscle tissue on opposite sides of the keel bone, actuates injection, and retracts the needles. Starting is initiated by the operator's hand which grasps the bird's legs.

Abstract: The present invention relates to an automatic injection apparatus for animals, in particular for chicks, which comprises a housing, a syringe with an injection needle giving the injection through an aperture on the front wall of said housing, a two-way air double action piston being connected to said syringe and to a source of air, activating means for said piston and means for connecting the syringe to a liquid container. Said apparatus has optionally additional parts, e.g. a timer fixing the length of the period of the injection; an air regulator; means for cleaning the air; counters measuring the numbers of animals being injected and/or pre-setting the number of animals to be injected; and a disinfecting device for the needle.