Abstract: A personal hygiene device comprises a tubular body constructed of a substantially watertight flexible material. The tubular body defines a cavity. An opening in the tubular body provides access to the cavity, which opening is selectively closable to create a watertight seal. A spray member, having a first end and a second end, is operatively connected to the tubular body at the first end. A channel in the spray member extends from the first end to the second end. The channel is exposed to the cavity at the first end. The second end of the spray member has openings that are exposed to the channel. Material in the cavity can travel from the cavity through the channel in the spray member, and exit through the openings in its second end. An adjusting means is selectively operable to control the amount of material that flows into the channel.

Abstract: An assembly for coupling a drug delivery device to a cartridge is disclosed. Optionally the assembly includes a coupling, for example a cannula, having one end extending toward the cartridge. The cartridge is optionally aligned by a guide. Optionally the cartridge has a limited freedom of movement. The coupling is optionally supported by a mount. In some embodiments, the mount is compliant enough that the end of the coupling that extends toward may move to said limited freedom of movement under a force less than a leak threshold of the connection between the coupler and the cartridge.

Abstract: In one aspect, the present invention provides therapeutic-agent-releasing medical devices which comprise at least one region of piezoelectric material. Therapeutic agent release is initiated or increased when the piezoelectric material is subjected to mechanical stress, which leads to the development of a voltage across the piezoelectric material. This voltage is used to initiate or increase therapeutic agent release.

Abstract: In alternative embodiments, the invention provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage, e.g., orthostatic lavage, e.g., for inducing the purgation (e.g., cleansing) of a gastrointestinal (GI) tract, including a colon; and methods for making and using them. In alternative embodiments, compositions and methods of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as Crohn's Disease, a poison, a toxin or an infection, e.g., a toxin-mediated traveler's diarrhea, or C. difficile or the pseudo-membranous colitis associated with this infection.

Abstract: An apparatus for percutaneous delivery of a sealant comprising: at least two fluid reservoirs, an introducer needle having a distal tip that is in fluid communication with at least one reservoir, a fluid delivery tube that is in fluid communication with a second reservoir, wherein the fluid delivery tube has a tip and wherein the fluid delivery tube is configured so that the tip of the fluid delivery tube does not extend past the distal tip of the introducer needle during use.

Abstract: The present invention provides a pharmaceutical composition comprising a chemical compound or a herb extract or the combination having at least one of the activities of antiviral, antibacterial, antifungal, anti-inflammatory, anti-allergy, anti-cancer, promoting membrane healing or immunomodulating, for the treatment and prevention of a disease of a mammal. The pharmaceutical composition is to be delivered into the hard-to-reach sinuses of a mammal by using a unique sinonasal delivery device. The invented method of treating a mammal disease reduces infectious and inflammation without causing antibiotic resistance or clinical significant adverse events.

Abstract: A self-contained portable apparatus for administration of a drug solution includes a housing having an enclosure for receiving a flexible pouch containing a drug solution, the output of which is connectable to a conduit for delivering the drug solution to a recipient. A pressurization system is arranged for providing a constant and controllable gas pressure to the housing in order to obtain a controllable delivery of the drug solution. The pressurization system includes a pressure source for delivering positive pressure gas; a pressure accumulation tank connected to the source and the second chamber; a one-way valve arranged between the pressure source and the pressure accumulation tank; and a mechanical pressure regulator arranged between the pressure accumulation tank and the housing. Hereby, an extremely stable and well controllable output pressure and output flow is obtainable.

Abstract: A disposable manual irrigation pump system comprises a manual foot pump operatively coupled to a fluid reservoir and an associated intraprocedural device. The pump system is configured to provide a substantially continuous fluid supply at a desired flow rate from the fluid reservoir to the associated intraprocedural device along a first direction without backflow of fluid along a direction opposite the first direction.

Abstract: A palm-controlled device is disclosed for injection of a substance into an organism. The device includes a palm-receiving surface for receiving a palm of a hand, the palm receiving surface being shaped so that the palm is substantially parallel to a surface of an injection site of the organism while operating the device. The palm receiving surface can also be shaped so that the palm is substantially perpendicular to a surface of the injection site. The device also includes an injector having at least one pre-filled syringe, the palm-receiving surface being cooperative with the injector such that when pressure is applied to the palm-receiving surface, the injector is actuated so as to inject contents of the at least one pre-filled syringe. Actuation of the injector is by gradual pressure; not sudden motion. Single or multiple doses of same or different medications can be included in a single injector.

Abstract: A fully manually powered infusion device provides both basal and bolus delivery of a liquid medicament to a patient. In some embodiments, the device includes a main reservoir that supplies the liquid medicament, an outlet port that delivers the liquid medicament to the patient, a basal dispenser that delivers a substantially constant flow of the liquid medicament to the outlet port, and a manually actuated bolus pump that delivers a bolus dose of the liquid medicament from the main reservoir to the outlet when actuated. The basal medicament supply delivers a volume of the liquid medicament from the main reservoir to the basal dispenser consonant with each actuation of the bolus pump.

Abstract: A dispenser head for mounting on a fluid dispenser, said dispenser head comprising a body (1) provided with a dispenser orifice (10), said head being provided with a cap (2) that is displaceable between a closed position, in which it covers said dispenser orifice (10), and an open position, in which it does not cover said dispenser orifice, said cap (2) being connected in permanent manner to said body (1), regardless of the position of said cap.

Abstract: According to one embodiment, a transdermal drug administration apparatus includes a first member having a protrusion on a facing surface opposed to a skin and a guide hole in the protrusion and a second member having a needle portion located in the guide hole and movable in a first direction across a surface of the skin.

Abstract: A device and method to accept a setting of a maximum volume of a drug that is introduced into a subcutaneous channel upon a patient's direction, while retaining a pre-designated flow of the drug to the channel over an extended period after accounting for such maximum volume.

Abstract: A catheter syringe conveyor with a needle guard housing is adapted to facilitate the insertion of a catheter into a targeted blood vessel. A catheter syringe is slidably situated within a hand-held housing structure; a syringe holder that is slidably connected to the housing allows a technician to maneuver the catheter syringe up and down within the housing. At least one stabilizer finger is attached to the bottom of the housing. After a blood vessel is penetrated by the needle of the catheter syringe, the technician maneuvers a catheter pusher to lower the catheter off of the needle and into the blood vessel. After the catheter is inserted, the technician is able to slide the catheter syringe back up within the housing to move the needle within the protective walls of the housing for safety, and a syringe lock holds it there securely for safekeeping.

Abstract: The present invention relates to a container for a disposable needle or cannula, intended to facilitate needle or cannula placement for the infusion of a liquid drug under a patient's skin, the container comprising: a cylindrical housing (1; 101) in which there are defined a cap (1a; 101a) and a sleeve (1b; 101b) provided with a resting base (1c; 101c), said cap (1a; 101a) being axially slidable relative to said sleeve (1b; 101b) when a sufficient pressure is exerted on said cap (1a; 101a); a needle (21; 121) or cannula, which is located inside said housing so as to be directed towards said resting base (1c; 101c) for the infusion of the drug; a retaining member (9; 109), which is located within said housing (1; 101) between said cap (1a; 101a) and said sleeve (1b; 101b) and to which said needle (21; 121) or cannula is secured; said container being equipped with a releasing member for releasing said needle (21; 121) or cannula when said cap (1a; 101a) is made to slide on said sleeve (1b; 101b).

Abstract: An intravenous catheter introducing device includes a needle hub slidably inserted into a barrel and holding a needle cannula, a biasing member disposed to bias the needle hub to a rear position so as to retract the needle cannula in the barrel, and an easy release unit including an engaging wall segment which is attached to an outer surface of the barrel, two flexible squeezed wall segments which extend from the engaging wall segment and which is squeezable so as to move two latch members to steer clear of a retained end of the needle hub through an access hole in the barrel, thereby permitting the biasing member to bias the needle hub towards the rear position.

Abstract: A drug delivery platform is provided for delivering a controlled infusion of a drug to an individual. The drug delivery platform includes a reservoir for receiving the drug therein and a hydrogel engageable with the reservoir. The hydrogel is movable between a first configuration and a second configuration wherein the hydrogel exerts a pressure on the reservoir to urge the drug therefrom in response to a predetermined stimulus. A flow guide distributes the predetermined stimulus over the hydrogel in response to activation by an individual.

Abstract: A device is provided for application of lubricant in an urethra to thereby facilitate insertion of a medical instrument into the urethra. The device (1) has a receptacle (2) having a lubricant-containing space (3) and a gripping part (4) and spout (5) connected to the gripping part (4). The outer end (5a) of the spout (5) is insertable into the urethra of a patient through the urethra orifice and provided with an outlet opening (6) connected to the lubricant-containing space (3) in the receptacle (2) which is grippable and manipulatable by gripping with fingers about the gripping part (4) of the receptacle (2), the gripping part (4) being deformable so that lubricant from the lubricant-containing space (3) can be squeezed out through the outlet opening (6) of the spout (5) by compression of the gripping part (4) with the fingers.

Abstract: The present invention relates to a method and apparatus for locating a site of intraosseous infusion and for relieving strain and stress on the infusion site. The template patch uses a key anatomical feature of the bone as a reference point to a target zone for infusion that is located a predetermined distance away from the feature. The template patch has a tube clamp and a covering that protect the infusion site from external forces.

Abstract: Dental anesthetic injection apparatus and methods for administering dental injections are disclosed. One embodiment comprises a portable device comprising a foot pedal, a control unit and a delivery head which receives a disposable cartridge of dental anesthetic and connects with a disposable syringe kit. The portability of this unit facilitates placing the dental cartridge within the dentist's field of vision while administering an injection. This and other embodiments provide a pen-grip type of needle grip which is movable independently of the anesthetic cartridge, and a programmable flow rate. Other embodiments comprise delivery heads mountable on dental equipment or fixtures, such as the dental chair.

Abstract: An animal syringe assembly having a direct bottle mount for receiving and retaining a liquid medicine bottle. In one embodiment, the syringe assembly includes a medicine syringe having a plunger extending from an end of an elongated shaft into a medicine dosage chamber. The shaft includes an interior axial conduit extending substantially therethrough which communicates with the medicine dosage chamber. A handle for actuating the medicine syringe includes a direct mount for receiving and retaining a liquid medicine bottle. The bottle mount provides direct fluid communication from the liquid medicine bottle to the interior axial conduit of the shaft of the medicine syringe. Vaccine is drawn into the medicine dosage chamber from the liquid medicine bottle through the interior axial conduit.

Abstract: The present invention relates to a drug delivery device for mixing and delivering a drug by injection. The device includes a housing having a first port or opening therein that receives a first container that contains a fluid or powdered drug, for example a lyophilized drug. The housing can also include a second port or opening that receives a second container that contains a fluid to be mixed with the drug to form an injectable fluid. The device includes a manifold having a channel that fluidly connects the first and second containers. A penetrating membrane such as a needle is used to inject the drug into a patient which is in fluid communication with the first container. The needle is movable from a storage position in the housing to an injection position extending through the housing.

Abstract: A blood-collection position indicator facilitating blood collection is provided. An adhesive layer is positioned on the back face of a substrate portion having a convex cross section and a circular planar shape, and at its center, a through hole going through the substrate portion and the adhesive layer is provided to serve as a blood collection hole, thus obtaining a blood-collection position indicator. In the blood-collection position indicator, the protruding portion serves as an attachment part to be attached to the tip of a lancet device, and the protruding portion is inserted into a hole of the tip of the lancet device, thus attaching the blood-collection position indicator to the tip of the lancet device. Adhesive strength of the adhesive layer to the skin is set to be stronger than attachment strength of the attachment part to the tip of the lancet device. Consequently, only the first blood-collection position indicator remains on the skin after the lancet device is used.

Abstract: A prefilled syringe of cartridge barrel having a tamper evident closure. Tamper evidence is provided by: a frangible tip seal which is integral with the tapered tip of the barrel; a frangible tip cap covering the tip, the tip seal and a portion of the distal end of the barrel; and an overwrap covering the frangible tip cap and the distal end of the barrel sealed to the distal end of the barrel by a tamper evident seal. The tapered tip is optionally equipped with a luer collar to receive an external luer connector. Alternatively, the tapered tip can be provided with a bore therethrough which can be closed with an elastomeric plug and the external connector can be a tubing conduit.

Abstract: A syringe is provided that has an opaque barrel and a light colored outlet portion. The opaque barrel protects dental composite material or other light-activating material contained in the barrel from premature exposure to light. The light colored outlet portion has a color that is similar to that of the dental composite material. The outlet portion may be tubular and extend coaxially within the barrel beyond the barrel. The outlet portion may include a divider that divides the material into at least two separate portions.

Abstract: A radiographically opaque spinal marker needle having a lower portion consisting of a small bore hollow needle and an upper portion having a larger outside diameter. An intermediate penetration restriction member fixed to and surrounding the marker needle at a point proximate the junction of the upper portion and the lower portion limits the depth of penetration of the hollow needle into the patient or tissue, provides stability, and forms a large observable mass on an X-ray. In an alternative embodiment the larger upper bore portion is in the form of a syringe and includes a prefilled ampule of dye within the syringe for injection into the patient by a plunger assembly. The upper portion may be separable from the lower portion at a point above the pentration restriction member.

Abstract: A medical instrument comprises a needle which is movable between an extended operative position where the needle is exposed for use and a retracted inoperative position where the needle is covered so as to reduce the likelihood of inadvertent contact with the needle. The instrument also includes a needle biasing means which normally urges the needle toward its retracted position and an actuator movable between a position of interference with movement of the needle to its retracted position and a position out of interference with the needle to permit the needle biasing means to act on the needle and urge the same toward its retracted position.