Abstract: A plastic pre-filled syringe which includes an open ended barrel sealed at one end by a moveable stopper and sealed at the other end by a closure frangibly connected to the syringe. The syringe also includes an overcap which can be moved so to engage with the closure whereby removal of the overcap will cause the closure to be separated from the rest of the syringe and reveal the contents for injection.

Abstract: Testicular prosthesis and method of manufacturing wherein the testicular prosthesis has a saline or other biologically safe fluid filled silicone elastomer shell which includes a self-sealing injection site for filling the prosthesis and a tab for suturing the testicular prosthesis into position in the scrotum. A method of filling and a method of identifying and serialization is also provided.

Abstract: A medicine administering device for nasal cavities, comprising a capsule holding section formed with a capsule containing powder-state medicine. An air supply section is connected to the lower end of the capsule holding section and formed with an air supply passage which is in communication with the capsule accommodating chamber. A branched passage section is connected to the upper end of the capsule holding section and has an air flow passage in communication with the capsule accommodating chamber. The air flow passage is bifurcated to form first and second outlet passage portions which are arranged to form a generally Y-shape. First and second medicine passages are formed such that air from the branched passage section flows therethrough to carry the medicine in the capsule into right-side and left-side nasal cavities of a patient. The first and second passages are respectively in communication with the first and second outlet passages of the branched passage section.

Abstract: The present invention relates to a puncture method and a puncture system. More specifically, the objective of the present invention is to carry out the aspiration of a sample from a human organ or an animal organ and the inner examination thereof, without the outward leak of the fluid and the like in the organ.The puncture method and puncture system of the present invention is in the following structure; making a parasol part arranged on a reservoir adhere through an adhesive to the site to be punctured, inserting a needle body through a sealing part of the reservoir into the site to be punctured to draw out the inner fluid, the leak of the fluid can be prevented by the reverse operation of the sealing part.

Abstract: A manually-severable coupling device for coupling two tubes (12a, 12b), particularly useful in peritoneal dialysis, including a flexible plastic member having passageways (30) therethrough and formed with tubular end sections (31, 32) for receiving tubes (20, 24) to be coupled, an annular groove (33) formed intermediate the tubular end sections defining a flexible, weakened, annular web (33) capable of being severed by rotating one of the tubular end sections (31, 32) with respect to the other, and a finger gripping formation (34, 35) integrally formed in each tubular end section (31, 32) on opposite sides of the weakened annular web (33) grippable by a user to rotate the tubular end sections with respect to each other to sever them from each other along the weakened annular web (33).

Abstract: An injection site and unsharpened drug transfer spike for facilitating coupling a syringe to a fluid line. The injection site has a uniquely designed housing and septum comprised of only two parts. The drug transfer spike has a positive locking member for restricting retraction from the injection site once it is inserted for injecting a medicant. The positive locking member preferably comprises a annular ridge defined about the shaft of the drug transfer spike. The septum includes a pair of axially aligned, oppositely oriented conical recesses with adjacent apices either separated by a thin membrane or intersecting at the time of manufacture. The housing has an inlet for receiving the septum and comprises a plurality of fingers with inwardly extending tabs for constraining the septum therewithin. The septum is ideally adapted to be applied to injection sites, Y-connectors, vial adaptors, single or multi-dose vials and blood collection tubes.

Abstract: Disclosed is a connector for introducing medication into a patient in a safe, convenient way. It comprises a pair of plastic tubular members adapted to be manually pushed together to engage in a male-female relationship, and a locking mechanism that detachably secures the members together. The male member has a sealed entry port at its end, and the female member safely houses within it a needle which centrally pierces the seal of the port upon engagement of the members. Preferably, the locking mechanism provides a "click" sound when it locks the members together.

Abstract: Small compression type injection site in the form of a self-sealing septum-like member that is self-sealing for hypodermic needle punctures and the like and a method of manufacture. Compressive stresses are introduced into a stretched elastomeric rod, whereby the decreased diameter cross section is maintained by placing a wrapping around and about the stretched rod and adhesively sealing it thereto. Sliced cross-sectional pieces of the rod then provide injection sites to be incorporated into the wall of an implantable prosthesis as by bonding or the like.

Abstract: A surgically implantable access port device is disclosed. The device includes a housing, a self-sealing septum, and a cup. The housing includes an internal bore leading to an upper opening, and the bore is defined by a cylindrical side wall having an inwardly protruding ledge located beneath the upper opening. The self-sealing septum is received in the bore at a location closing the upper opening and bearing against the ledge. The cup is received in the bore, and cooperates in a fixed association with the side wall of the bore to compress the septum against the ledge. The cup cooperates with the septum in defining a liquid retaining chamber. The device further includes a conduit connected to the cup and leading from the chamber to the exterior of the housing. Liquid may be injected into or removed from the chamber by penetration of the septum and passage through the conduit.

Abstract: An elastic plug assembly is provided for selective penetration by a needle. The elastic plug assembly comprises an elastic plug that is retained in a radially compressed state by a rigid plug retainer. The combined elastic plug and rigid plug retainer may be secured in a housing formed from an elastomeric material. The elastic plug may be penetrated by a needle. Upon removal of the needle, the radially compressed elastic plug will be urged toward its compressed condition with the space that had been occupied by the needle being completely filled to effectively achieve the sealing function of the plug. Needles may repeatedly be penetrated through the plug and removed as necessary, and the plug will efficiently return to its substantially solid sealed state after each successive needle removal.

Abstract: The connector assembly includes a female luer connector having a hollow needle disposed in recessed position within a rigid tubular portion. A rubber shield having a tubular portion and a septum at one end is positioned over the needle to maintain the needle in a sealed condition. A compression ring is disposed about the rubber septum to hold the septum in compression whereby the punctured area can be punctured many times without leaking when subjected to relatively high pressures. The male connector may be of any suitable type for pushing the rubber septum into the female connector for piercing by the needle of the female connector.

Abstract: This invention provides a non-kinking and thin-walled introducer sheath (10) having a flat wire metal coil (12) that lies within a plastic covering (20) fitted onto the exterior surface of the flat wire metal coil (12) and extends into a space between adjacent turns of the flat wire metal coil (12) without covering the interior surface. Each turn of the flat wire metal coil (12) has a thickness within the range between 0.75-3.0 mils with a width to thickness ratio lying between 12 and 80. A plastic adapter (30) is provided and is located at a proximal end of the sheath (10) for inserting guide wires through the sheath (10) into a vessel.

Abstract: A dripless cannula system usable with a syringe or other fluid container in a fluid sampling procedure and operable to minimize retention of residual fluids at a sampling site following the sampling procedure. In the preferred embodiment, a vacuum chamber operatively connected to a blunt cannula of the dripless cannula system is operative upon withdrawal of the cannula from the sampling site to draw residual fluids at the site into the vacuum chamber for subsequent disposal. The dripless cannula system of the present invention is a simple, effective apparatus for minimizing the presence of residual fluids at a sampling site following a sampling procedure.

Abstract: A valve for medical use has a cannula mounted on a hub and fixed in a fluid conduit so that the cannula points upstream. An elastomeric valve element is mounted on the hub within the conduit so as to enclose the cannula. The valve element has a first solid portion of circular cross-section disposed upstream of the cannula point which closes the conduit, a second hollow frustoconical portion within which the cannula point is disposed, and a third hollow cylindrical portion surrounding the cannula downstream from its point and fixed to the hub. The second portion has a frustoconical interior passageway. In use, the valve element is compressed by application of a medical appliance to the valve element first portion to cause the cannula point to pierce the first portion to provide a path for fluid flow through the conduit.

Abstract: Apparatus for administering dialysis, including a separable tubing coupling (32). The tubing coupling (32) consists of a hollow cylindrical element (42, 44) insertable into the lumens of the distal and proximal regions of the fluid delivery tube (16), and has a scored circumference at which the coupling can be broken-off by application of an adequate bending force. The device allows rapid and reliable disconnecting of the patient from the dialysis apparatus, without the need for scissors or a knife to be employed.

Abstract: A liquid containing thermoplastic unit dose container (1) which comprises a body portion (2), a neck portion (3) and an outlet opening (7) at the end of the neck portion (3) which is sealed by a non-resealable cap (4). The outside wall of the neck portion (3) comprises a thread engagement portion (8) which is located at or proximate the outermost edge of the neck portion (3) so that after removal of cap (4) thread engagement portion (8) is adapted to engage within an inwardly facing screw thread channel (14) at the end of a syringe. This enables sealing connection of the container (1) to the syringe so that liquid within container (1) may be directly transferred from the container (1) to the syringe.

Abstract: A subcutaneous implantable access port is formed of a housing having a pair of noncircular fluid cavities enclosed therein by a floor, walls upstanding from the floor, and a self-sealing septum positioned above each fluid cavity. The housing is constructed of a base, a septum support, and a cap. An outlet stem exits the base and communicates with the fluid cavities therein. The outlet stem has two prongs formed in a side-by-side configuration extending outwardly from the base. The prongs are formed within the stem channels in fluid communication with the fluid cavities. Protruding radially outwardly from the portion of said prong is a barb. Fluid injected into the fluid cavity through the septum flows through a smooth transition region in which the cross-sectional area is smoothly reduced from the corresponding fluid cavity. A locking sleeve provides radial inward pressure upon the catheter which is slid over the outlet stem, thereby insuring that the catheter remains mounted on the outlet stem.

Abstract: A hand-held apparatus and method for insufflating an abdominal cavity includes a compact gas supply unit comprised of a gas cartridge which has a pair of tandem piercable seals positioned inside the cartridge neck and which contains a predetermined mass of compressed gas. A cap having a puncture stem is engaged with the gas supply unit, causing the puncture stem to penetrate the piercable seals and release gas through the puncture tube and into a hollow needle positioned inside the abdomen. The tandem piercable seals are arranged such that as the gas supply unit is engaged with the cap, the puncture stem punctures the first piercable seal and the first piercable seal seals around it before the puncture stem punctures the second piercable seal, thereby preventing accidental loss of gas and preserving the entire mass of gas for insufflation.

Abstract: A hollow needle fixed in a chamber establishes a connection between an upstream coupling and a downstream coupling when it passes through a plug. The plug is made of a material such that it regains its closure properties when the needle is no longer passing through it, and it is pushed away from the needle by a spring to a closure position in which it fills the outlet opening of the downstream coupling. The connector is particularly suitable for use in medical applications.

Abstract: A medication dispensing device for implantation into an animal or human body, comprises a plurality of compartments each containing a dose of medicine to be dispensed and having a delivery opening permitting delivery of the medicine; a rupturable membrane sealing the delivery opening of each compartment, the membrane having a predetermined elastic deformation limit and a predetermined rupture point; and a membrane rupturing system associated with each compartment for rupturing the membrane thereof in response to an electrical signal.

Abstract: A drug delivery device is provided comprising a cartridge body including an upper portion defining a vial receiving area and terminating in a wall, the cartridge body including a cannula extending from the wall. A vial including a beneficial agent is coupled by a retaining member to the cartridge body in an inactivated position. The retaining member allows the vial to move to an activated position. The retaining member including an outer member and an inner member, the inner member separating from portions of the outer member as the vial moves from the inactivated position to the activated position.

Abstract: A self-sealing valve device for an angiographic catheter includes a housing having a first end adapted to form a luer lock connection with the proximal end of the angiographic catheter. A central bore extends between the first end of the housing and an opposing second end, and a deformable elastomeric slit seal is supported across the central bore to selectively seal the proximal end of the catheter. The slit seal is adapted to permit a guidewire to be passed therethrough and advanced into the catheter while sealingly engaging the walls of the guidewire to prevent blood loss through the catheter. The second end of the housing is provided with a female luer lock connection fitting for receiving the conical tip of a syringe, stopcock, or the like, and forming a pressure-tight connection therebetween.

Abstract: A connector assembly including an injection needle for providing fluid communication through a closed injection site at one end of an infusion line for infusing fluid therapy to a patient which includes an injection needle, a hub at one end of the needle, a tube connected to the hub, and a connector mounted to the hub. The connector includes a thread or other device for securing the connector to a complimentary connector provided the end of the infusion line. A second end of the needle extends beyond the thread or other device to permit the needle to pierce the injection site prior to engagement of the thread or other device with the complimentary connector and at least one of the two connectors is mounted for rotary movement relative to the needle and the injection site to permit the connectors to be secured together by rotary movement subsequent to piercing the needle through the injection site without rotating the needle.

Abstract: An improved endotracheal tube and an adapter for a standard endotracheal tube allow the performance of various medical procedures while maintaining continuity of respiration and protecting the care-provider from contact with potentially hazardous body fluids. The adapter comprises a rigid plastic Y-tube having a very large bore stopcock in one arm. In a preferred embodiment the endotracheal tube adapter further comprises a puncturable, resealing membrane having a first face in fluid communication with the interior of the adapter and a second face accessible to the exterior of the adapter. The adapter may additionally include an inflatable cuff circumferentially disposed within a bore of one of the tubes so as to allow axial engagement of a cylindrical object disposed within the bore of the tube. A single unit endotracheal tube assembly comprising the adapter and a conventional endotracheal tube is also disclosed.

Abstract: A composite implantable biocompatible vascular access port device for delivering a fluid medication to or withdrawing a fluid medication from the body. The device has a non-metallic housing defining an interior chamber with inlet and outlet openings, a self-sealing penetrable septum, a non-reactive chamber liner, and a non-reactive delivery conduit. The septum closes the inlet opening and provides a seal through which fluid medication may be injected into the chamber. The chamber liner underlies the septum and cooperates with it to isolate the injected fluid medication from the housing and from leakage into body tissue. The delivery conduit communicates with the interior of the liner, and extends through the outlet opening to convey fluid medication to the exterior of the housing.

Abstract: A valve for medical use has a cannula mounted on a hub and fixed in a fluid conduit so that the cannula points upstream. An elastomeric valve element is mounted on the hub within the conduit so as to enclose the cannula. The valve element has a first solid portion of circular cross-section disposed upstream of the cannula point which closes the conduit, a second hollow frustoconical portion within which the cannula point is disposed, and a third hollow cylindrical portion surrounding the cannula downstream from its point and fixed to the hub. The second portion has a frustoconical interior passageway. In use, the valve element is compressed by application of a medical appliance to the valve element first portion to cause the cannula point to pierce the first portion to provide a path for fluid flow through the conduit.

Abstract: An improved, universally adaptable, medical intermediate connector having a large tubular opening at one end and a through passage running the length thereof, the body of the connector having a rectilinear cross section with plural planar sidewalls, one of the sidewalls having an extension with projecting fastening knobs and at least one of the sidewalls having a window therethrough, a resilient flexible and elongate strap selectively and adjustably attachable to the knobs and selectively extendable therefrom and returnable to the attachment knobs under tension. A cannula is secured to the body on the axis thereof and projects into the large tubular opening for communicating engagement with a septum inserted guidably into the tubular opening at one end and penetrable by the cannula. A luer socket is an axial extension of the body and communicates with the cannula via the passageway on the axis of the intermediate connector.

Abstract: A valve for medical use has a cannula mounted on a hub and fixed in a fluid conduit so that the cannula points upstream. An elastomeric valve element is mounted on the hub within the conduit so as to enclose the cannula. The valve element has a first solid frustoconical portion upstream of the cannula point, a second hollow frustoconical portion within which the cannula point is disposed, and a third hollow cylindrical portion surrounding the cannula downstream from its point and fixed to the hub. The second portion has a frustoconical interior passageway tapering inwardly from the first portion toward the hub. A supplementary metallic frustoconical sleeve is fixed within the second element interior so as to open outwardly toward the first element and enclose the cannula point. In one type of use, the valve element is compressed to cause the cannula point to pierce the first portion to provide a path for fluid flow through the conduit.

Abstract: A method and apparatus for administering dialysis including a breakable tubing coupling is provided wherein the tubing coupling is a hollow cylindrical element insertable into the lumens of distal and proximal sections of a fluid delivery tubing system, the breakable tubing coupling having a scored circumference on which the coupling can be broken and separated by application of a bending force. The breakable tubing coupling is suitable for medical applications including peritoneal dialysis tubing administration set utilization for administering fluid from fluid containers into a patient's peritoneal cavity through a peritoneal catheter and out of the peritoneal cavity and into a drain container wherein the tubing administration set having a tubing supply leg and a tubing drain leg requires means for separating the peritoneal catheter following dialysis at a predetermined location along the tubing path.

Abstract: An elastomeric member for occluding a medical terminal such as a junction terminal to provide a seal and penetratable to establish fluid connection by a blunt needle or cannula in which improved security against passage of contamination is provided. The needle or cannula preferably passes through a perforated passage. The passage can have at least two portions, one having a slit for normally sealing tightly in the absence of a cannula or needle and the other having a bore communicating with the slit and closely conforming to the cannula surface. Other sealing arrangements are detailed.

Abstract: A blood aspiration assembly has an aspirator receiver. The receiver has a housing with a rigid casing and a resilient plug, and a liquid flow chamber. The chamber has an offset lower wall surface, to create turbulence to remove air bubbles during initial set up. The offset wall can be elevated with an intermediate part of larger cross section to accommodate the blunt needle. The plug has a slit or perforation to allow passage of a blunt needle therethrough. The plug can have two parts of different compliance, with aligned slits or perforations. The blunt needle tip can be rounded or flat, with a side opening for the needle bore. The contour of the needle tip and the design of the plug are correlated such that the working force required to penetrate the needle tip into the plug perforation is considerably less than the force required for said needle tip to penetrate normal intact human skin of the hands or arms. A stop prevents the needle from contacting the aspiration chamber wall.

Abstract: The present invention provides a sheath for at least removably covering the blunt end of the cannula. The sheath allows the cannula to be presterilized and utilized without subsequent sterilization. The sheath comprises a body member defining an interior for receiving at least a portion of the blunt cannula, the body member including a first end and a second end, the second end having an opening for receiving at least a portion of the cannula. The first end including a wall member so constructed and arranged as to rip upon the exertion of a sufficient perpendicular force by an end of the blunt cannula. The body also includes side walls extending between the first and second end, the side walls are so constructed and arranged so as to slide back along the cannula toward the second end upon the tearing of the first end by the cannula and the application of a sufficient force upon the side walls.

Abstract: A multiple chamber subcutaneously implantable infusion port and catheter assembly is formed from a small number of plastic components that are easily injection molded and assembled. The components are constructed so that a catheter assembly is easily and securely bonded to the port.

Abstract: A medical device which presents the backflow of fluid therethrough is particularly useful as a bloodless catheter assembly, that is, prevents the backflow of blood through the catheter by utilization of a self-closing valve carried in a hollow catheter housing to one end of which a catheter is fixed so as to provide a fluid passage through the catheter and catheter housing. The fluid passage in the catheter housing is sealed by a self-sealing valve element extending transversely across the passage upstream from the catheter. A hollow needle is held in the catheter housing downstream of and pointed at the valve element. Attachment of a fluid dispensing medical appliance to the other catheter housing end forces the valve element downstream onto the needle so as to pierce the valve element and open a fluid passage from the catheter housing upstream of the valve element through the hollow needle to the catheter.

Abstract: A device for delivering medication into a human body, comprising a catheter having proximate and distal ends, and first and second lumina extending substantially the entire length of the catheter. A first opening in the catheter near its distal end drains fluid from a body when the catheter is inserted therein. There is a second opening in the catheter between the first opening and the distal end of the catheter. The second opening is fluidly connected with the second lumen. A diaphragm is located adjacent to the second opening for blocking off the second opening from the second lumen, and the diaphragm is burstable by a predetermined pressure for unblocking the second opening for fluidly connecting it with the second lumen. Thus, medications can be safely administered without the possibility of premature contact of the medication with the body. The catheter is particularly well suited to the administration of toxic substances such as BCG vaccine into the bladder of bladder cancer patients.

Abstract: A blood sampling kit and the method of using the blood sampling kit are disclosed wherein an arterial blood gas syringe having a venting means associated therewith is used in combination with a blood collection tube holder having a double ended needle mounted therein and a stopper assembly consisting generally of a cylindrical member with a central opening and a flexible diaphragm member extending across the opening such that the stopper assembly and syringe assembly are inserted into the blood collection tube holder to obtain a blood sample from a patient in the syringe assembly and, once the blood sample is obtained, the syringe assembly and stopper assembly are removed from the blood collection tube holder and the stopper assembly protects the blood sample from exposure to the atmosphere.

Abstract: An injection site for the infusion of a medicament into a flow path for a parenteral fluid and, more particularly, an injection site which is essentially self-priming and air-occluding and which is of extremely simple construction and easily assembled. Furthermore, the invention is also directed to an injection site of the type described herein which is especially adapted for use as an injection port of a Y-connector utilized for an intravenous administration set. The device incorporates a self-sealing puncturable member of resilient material, such as rubber, which member is of a substantially spheroid configuration, the tubular segment so as to be in close proximity to the and which is swage-molded into a receiving housing in the tubular segment so as to be in close proximity to the inlet tubing for the flow path of the parenteral fluid.

Abstract: A catheter hub assembly is disclosed wherein the assembly contains a membrane useful in preventing backflow of blood into the flash chamber. The hub assembly contains a membrane opener which operates upon the insertion of a luer locking mechanism into the catheter hub. This membrane opener allows flow of nutritional fluid into the body by causing the opening of the membrane during use of the catheter after removal of the catheter needle.

Abstract: A tube assembly is provided which includes a tubular body of rigid resin having an open end and provided with a substantially annular frangible portion and a plug of flexible resin mounted in sealing fit on the tubular body for closing the open end.

Abstract: A surgically implantable infusion port includes a housing portion, a penetrable elastomeric septum portion which cooperates with the housing portion for defining an interior cavity and a catheter element which extends outwardly from the interior cavity for dispensing medication therefrom at a predetermined location in the body of a patient. The elastomeric septum portion is penetrable by a hypodermic needle for dispensing medication in the interior cavity, and it is laterally compressed to enhance the ability of the septum portion to reseal itself after being repeatedly penetrated. A septum assembly including a similar laterally compressed septum element can also be utilized as a penetrable barrier between various liquids and gases.

Abstract: An assembly for the administering of liquid, such as medicines, saline solutions, etc. intravenously to a patient incorporating a sterile, closed system specifically designed for set-up and use by a patient in a domestic environment and in situations where the patient administers fluid to himself with a minimum of medical personnel supervision or aid.

Abstract: This invention related to a simple device for hypodermic pressure-injection which does not make use of needles for introducing the vaccine into the patient's body, and which is fully constituted by low cost disposable material self-destroying after being utilized a single time. This device already contains within it, a single metered dose of vaccine or medication to be injected and, when in use, it comprises solely four elements; and injector nozzle with an outlet orifice, a sealing disc, a cylindrical body and the dose itself of vaccine to be injected.

Abstract: A branch tube comprising a main tube defining a continuous flow path and one or two branches connected to the main tube has a closure member connected to one end of the main tube to block the flow path thereof. The closure member is integrally molded with the main tube so that a continuous smooth flow path extends through the main tube up to the closure member and the closure member is breakable from the main tube to open the flow path. A tubular sleeve is connected to the main tube so as to surround the closure member.

Abstract: An assembly of a tube having a breakaway plug member mounted on one opening thereof is provided. The plug member has an open end and a closed end, and includes on its inner surface a first inner-wall portion extending from the open end toward the closed end a predetermined distance which is fixedly secured to the one open end of said tubular body, and a second inner-wall portion defining a space therein which extends from the first inner-wall portion to the closed end. The plug member also includes on its outer surface a thin-walled frangible portion located on or radially outside the second inner-wall portion which is breakable to allow separation of the plug member from the tubular body. The one open end of the tubular body extends in said space beyond the thin-walled frangible portion toward the closed end of the plug member.

Abstract: A matrix septum material, especially useful in medical applications such as implantable drug delivery devices, is provided by retaining a penetrable, resilient, elastomer under compression between webs having peripheries which frame perforations to form individual, self-sealing cells in the matrix.

Abstract: In a blood bag system for plasma transfusion and cell return including two or more blood bags containing anticoagulant and connected to a puncture needle through two or more branch tubes and a common main tube, a cell return port is connected to the branch and a breakable flow path closure is inserted in one branch tube adjacent the branch. When broken, the flow path closure allows fluid communication through the branch tube. Blood is first collected in the first blood bag, which bag is sealed when filled and separated from the system. Then, the flow path closure is manually broken to permit blood collection into the second blood bag.

Abstract: An injection reservoir or button is adapted for implantation beneath the skin of human and animal patients in conjuction with tissue expanders and drug delivery devices. The injection reservoir includes a base and an exterior wall which define a chamber of liquid reservoir. A duct connects the chamber with an expandable bag of the tissue expander. An elastic rubber member is affixed within the interior of the chamber to act as a sealing member. The rubber member is an inverted dome and is self-sealing to needle punctures because it has a concave interior side which is under compression as a result of having been manufactured into a substantially dome-shaped configuration and thereafter inverted. A metal guard plate is included within the interior of the chamber to guard the base against accidental puncture by an over extended hypodermic needle.

Abstract: A portable controlled release osmotic infusion device, which can be activated on demand by the user, comprising a rigid housing containing:a. a fluid-imbibing assembly, comprising a solvent-containing chamber and a solute-containing chamber; the two chambers separated by a rigid semipermeable membrane covered by a thin taut foil seal,b. a drug-containing chamber separated from the fluid-imbibing assembly by a leakproof impermeable elastic diaphragm, which expands into the drug-containing chamber in use and drives the drug through a dispersing orifice at a steady rate, andc. an activating device which ruptures the foil seal described in (a) above and initiates the osmotic action of the device.The osmotic device is filled with drug in solution or suspended form during manufacture and can be stored without deterioration of the contents for prolonged periods of time.

Abstract: A septum is provided for use with implantable ports used for repeated drug delivery infusions. The septum allows for a substantially higher (more than twice) number of punctures prior to leakage and failure. This is achieved by the use of two different Shore A durometer hardnesses for different sections of the septum, one of harder material than used in prior art septums for the main body of the septum, and a section of much softer Shore A duromater hardness adjacent the inner surface of the septum for greater sealing facility when a needle is withdrawn. In addition, the greater hardness of the main body allows for greater stability of the needle when in place in the septum.

Abstract: An implantable fluid transfer device or septum which includes a hollow spherical housing containing a chamber therein for receiving fluid. A needle infuses fluid into or withdraws fluid from the chamber. The housing has a surface that is capable of both omni-directional penetration by the needle and sealing itself when the needle is withdrawn from the housing. A spherical needle stop is provided with the housing to prevent the needle that accesses the chamber from one side of the housing from passing through the opposite side of the housing.