Bag Type Patents (Class 604/408)
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Patent number: 11905070Abstract: A repulpable zipper is provided for attachment to a repulpable flexible package. The repulpable zipper is formed using a water-soluble polymer combined with a repulpable material, such as a plant-based cellulose material. The repulpable zipper enables the repulpable package to be opened and closed by the consumer, so that the consumer has the option to determine, change or manipulate the contents of the repulpable flexible package.Type: GrantFiled: January 28, 2021Date of Patent: February 20, 2024Assignee: Illinois Tool Works Inc.Inventors: Eric P. Plourde, Christine N. Shimel, Lars G. Wihlborg
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Patent number: 11896656Abstract: A method is described for reconstituting lyophilized mutant diphtheria toxin in dimethyl sulfoxide for use in producing pneumococcal capsular polysaccharide mutant diphtheria toxin conjugates.Type: GrantFiled: April 25, 2019Date of Patent: February 13, 2024Assignee: MERCK SHARP & DOHME LLCInventors: Patrick Leonard Ahl, Akhilesh Bhambhani, Christopher Jon Farrell, Patrick McHugh, Morrisa C. Jones, Daniel D. Roth, Jessica R. Sinacola, Justin Stanbro, Matthew P. Watson, Emily Wen, Michael A. Winters
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Patent number: 11891198Abstract: Systems, methods, and computer-readable media are disclosed for roll-formed containers for shipping. In one embodiment, an example container for an item may include a rectangular sheet of formable material, the rectangular sheet having a first crease line, a second crease line separated from the second crease line by a distance, a first crease pattern disposed adjacent to the first crease line, and a second crease pattern disposed adjacent to the second crease line. The container may include a sealant disposed about three sides of the rectangular sheet.Type: GrantFiled: February 4, 2022Date of Patent: February 6, 2024Assignee: Amazon Technologies, Inc.Inventor: Garett Ochs
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Patent number: 11883577Abstract: A fluid collection apparatus for use in negative pressure wound therapy. The fluid collection apparatus includes a flexible bag having a first opening and a second opening. The bag includes a structure defining a fluid pathway connecting the first opening and the second opening. The pathway is circulative and contributes to orientation independence of the bag in use. The bag further includes a load-bearing component.Type: GrantFiled: January 4, 2022Date of Patent: January 30, 2024Assignee: ConvaTec Technologies Inc.Inventors: Robert Gordon Maurice Selby, Lawrence Mark Baker, Steven Paul Gowers
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Patent number: 11873156Abstract: A flexible pouch for packaging contents has a pair of leg portions having gussets. A bridge connect the leg portions. At least one arm extends upwardly. The pouch can be formed to represent various objects such as letters. The pouches can be formed with compartments for holding different components. The compartments may be separated by frangible seals to permit components to be mixed within the pouch.Type: GrantFiled: December 2, 2020Date of Patent: January 16, 2024Assignee: Pouch Pac Innovations, LLCInventor: R Charles Murray
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Patent number: 11844746Abstract: The invention relates to a protective housing for a biopharmaceutical liquid bag having a lower shell with a bottom and side walls, and an upper shell. The upper shell includes a housing for receiving the bag, and can be inserted into the lower shell, in such a way that the opening of the housing is adjacent to and facing the bottom of the lower shell, and in such a way that the upper shell is laterally held in place between the side walls of the lower shell.Type: GrantFiled: March 28, 2018Date of Patent: December 19, 2023Assignee: Sartorius Stedim FMT SASInventors: Stephane Baud, Frédéric Bazin
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Patent number: 11844888Abstract: A photonic corpuscular irradiator machine, having an irradiation chamber having an external wall, a top edge, a bottom edge, an internal wall, and a spiral ridge; and an ultraviolet irradiation lamp. A machine assembly has an irradiation chamber housing, a bar code scanner, a control panel, an automatic peristaltic pump, and an intensity dial; and further having first and second blood bags. The external wall and the internal wall define a peripheral channel between them, and the spiral ridge extends within the peripheral channel. Blood from the first blood bag travels through an inlet port and is forced upwardly in a spiral motion along the spiral ridge within the peripheral channel and exits from an outlet port to the second bag. The irradiation bulb within of the cavity irradiates ultraviolet light to the blood within the peripheral channel. The ultraviolet light treats blood containing COVID-19 and/or pathogens.Type: GrantFiled: March 12, 2021Date of Patent: December 19, 2023Inventor: Danilo O. Fernandez
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Patent number: 11827403Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.Type: GrantFiled: March 3, 2020Date of Patent: November 28, 2023Assignee: GRIFOLS, S.A.Inventors: Jordi Boira Bonhora, Miquel Faba Vilella, Daniel Fleta Coit
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Patent number: 11827875Abstract: A method of manufacturing a composite sensor assembly includes: providing a port including a high surface tension thermoplastic, the port having a hollow tubular portion and a base having a polymer surface; fusing the polymer surface of the port to a wall of a polymeric bioprocess vessel so that the port communicates with an opening in the wall; and retaining a sensor unit within the hollow tubular portion of the port with an adhesive, at least a portion of the sensor unit being polymeric, wherein the port provides the sensor unit access to an interior of the polymeric bioprocess vessel.Type: GrantFiled: July 8, 2021Date of Patent: November 28, 2023Assignee: Finesse Solutions, Inc.Inventors: Mark Selker, Barbara Paldus, Timothy Johnston
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Patent number: 11806506Abstract: An intravenous fluid delivery apparatus (IFDA) includes a body having two or more docks, wherein each dock includes a dock outlet and is configured to engage with a container. The IFDA further includes a fluid interface having two or more interface inlets and an interface outlet, wherein the two or more interface inlets are in fluid communication with the interface outlet, and two or more supply lines, each supply line disposed between one of the dock outlets and one of the interface inlets, wherein the interface outlet is configured to connect with an intravenous line.Type: GrantFiled: June 1, 2021Date of Patent: November 7, 2023Assignee: DASH ANESTHESIAInventor: Dane Hassani
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Patent number: 11786646Abstract: A container for warming fluids comprises an inlet port, an outlet port, a fluid conduit configured for fluidly communicating the inlet and outlet ports, and deflection sections. The fluid conduit has a non-constant maximum width in a direction of fluid flow through the fluid conduit. The deflection sections further comprise an entry section and an exit section, each respective exit section being arranged downstream, in the direction of fluid flow, from each respective entry section. The maximum width of the fluid conduit decreases along the direction of fluid flow through the entry section over a first distance and the maximum width of the fluid conduit increases along the direction of fluid flow through the exit section over a second, different distance. An apparatus for warming fluids in, an extracorporeal blood circuit including, and a blood treatment apparatus including the container are also provided.Type: GrantFiled: May 9, 2018Date of Patent: October 17, 2023Assignee: Gambro Lundia ABInventors: Dominique Pouchoulin, Eugen Nisipeanu
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Patent number: 11786442Abstract: A liquid transfer device includes a vial adapter that receives a vial. The vial adapter includes a vial spike that punctures a vial stopper of the vial and defines a vial spike lumen. The liquid transfer device also includes an intravenous (IV) port that receives a port spike of an infusion set. The liquid transfer device also includes a connector body including a vial adapter lumen in fluid communication with the vial spike lumen, a barrel connected to the IV port, and an IV spike including a central wall. The central wall defines a first IV spike lumen in fluid communication with the vial adapter lumen and a second IV spike lumen in fluid communication with the IV port. The first IV spike lumen and the second IV spike lumen are separated by the central wall.Type: GrantFiled: September 26, 2022Date of Patent: October 17, 2023Assignee: West Pharma. Services IL, Ltd.Inventors: Yossi Bar-El, Elisheva Fabrikant, Niv Ben Shalom
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Patent number: 11740019Abstract: Provided is a loading tray assembly for housing a lyophilization container and a related system and method. The loading tray assembly includes a chassis including a contact void configured to facilitate direct contact between the attached lyophilization container and a lyophilizer shelf. The method includes securing a multi-part lyophilization container including a peelable seal on a lyophilization loading tray assembly, inputting a liquid into a non-breathable section of the lyophilization container, loading the tray assembly into a lyophilizer, freezing the liquid, applying heat energy and a vacuum, the vacuum causing an opening of the peelable seal and occluding the lyophilization container to isolate the frozen liquid.Type: GrantFiled: December 1, 2022Date of Patent: August 29, 2023Assignee: Terumo BCT Biotechnologies, LLCInventors: Nathaniel T. Johnson, Dennis A. Bridges, Alexander Du Nguyen, Margaret V. Kwiat, Kestas P. Parakininkas, Rylan A. Summit
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Patent number: 11690952Abstract: A method of dispensing a therapeutic fluid from a line includes providing an inlet line connectable to an upstream fluid source. The inlet line is in downstream fluid communication with a pumping chamber. The pumping chamber has a pump outlet. The method also includes actuating a force application assembly so as to restrict retrograde flow of fluid through the inlet while pressurizing the pumping chamber to urge flow through the pump outlet. A corresponding system employs the method.Type: GrantFiled: July 13, 2020Date of Patent: July 4, 2023Assignee: DEKA Products Limited PartnershipInventors: Dean Kamen, Larry B. Gray, Eric Yeaton
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Patent number: 11684921Abstract: The pocket detection platform (PDP) detects pathogens, toxins and chemicals of interest simultaneously by way of a multi-channeled, soft see-through plastic pouch design that consists of inner and outer compartments that promote compartmentalization and/or unidirectional sample flow. The platform enables the concurrent running of multiple detection assay techniques such as lateral flow immunoassays (LFI), Isothermal molecular assays (i.e., Recombinase Polymerase Amplification, or RPA) and/or paper-based chemical assays (i.e., M8, pH paper) from a single wet or dry sample with minimal sample processing. The PDP reduces soldier overburden by decreasing size weight, and power (SWaP) as well as training time, electronic burden, while providing a flexible, customizable assay platform that can be rapidly produced, assembled, sustained, and when contaminated, easily to dispose of.Type: GrantFiled: August 7, 2020Date of Patent: June 27, 2023Assignees: Leidos, Inc., The United States of America as Represented by the Secretary of the ArmyInventors: Kelley D. Betts, Jennifer W. Sekowski
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Patent number: 11648147Abstract: An instrument 10 to prepare an intra-uterine device 30 for insertion in uterus 50 of woman, comprising a downfolding device 20, a graduated tube 16, a push rod 17, a stopper 15, and an IUD 30; the downfolding device 20 having a concave depression 41 on either side, an open channel 29 of a circular orifice 46 having a sector of angle measure 46A at least 220° and having an exit opening 48 initially marginally less than an external diameter 22B of the graduated tube 16, a root thickness 37B of the base 37 in-between the open channel 29 such that the exit opening 48 increases by the base 37 flexing; the graduated tube 16 has an internal diameter 22D of a far-end opening 22a of the graduated tube 16 sufficient to capture the stem 33 and both arms 32 of the IUD 30 in a downward triangular formation 51.Type: GrantFiled: July 23, 2020Date of Patent: May 16, 2023Assignee: Pregna International LimitedInventor: Mukul Taparia
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Patent number: 11633585Abstract: A medical connector that allows ventilation of vapor used in vapor sterilization and has an internal flow route that is tightly closable without using any separate clamping device. A medical connector includes a body having an internal flow route connected to an other flow route, proximal portions included in the body and having respective one-side connection ports at which the internal flow route is connectable to the one flow route, a distal portion having an other-side connection port at which the internal flow route is connectable to the other flow route, one-side lid portion, and an other-side lid portion whose state is switchable between a closing state and a ventilating state in which the other-side lid portion covers the other-side connection port such that ventilation is allowed.Type: GrantFiled: September 5, 2019Date of Patent: April 25, 2023Assignee: Nikkiso Company LimitedInventors: Shigeru Sasahara, Kazuhide Ono, Ryo Kato, Hironobu Sugiyama
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Patent number: 11559617Abstract: The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.Type: GrantFiled: September 12, 2019Date of Patent: January 24, 2023Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Winfried Brehm, Phillippe Laffay, Gerhard Wiesen
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Patent number: 11548665Abstract: The invention relates to a method and to a device for filling a medical packaging formed as a pouch. Preferably, the packaging is filled with liquid via a port, wherein the port is aerated with a protective gas, such as nitrogen, for example, during filling According to the invention, prior to filling with liquid, the packaging is filled with an inert gas, such as nitrogen, for example, which then provides the headspace of the filled and closed pouch. This results in a particularly low oxygen content in the headspace of the pouch.Type: GrantFiled: September 21, 2018Date of Patent: January 10, 2023Assignee: Fresenius Kabi Deutschland GmbHInventors: Joern Wittorf, Gerald Wegner, Witali Klan, Marius Ruffer, Stefan Faber, Denis Kosatsch, Behnam Zandnia
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Patent number: 11498284Abstract: The invention relates to a welding tool and to a method for pulse welding of plastic films for medical packs formed as bags. In general, the invention provides that the film material which is plastified during welding and thus free-flowing is specifically displaced into a deepened, edge-side inner region of the sealing surface by increasing the sealing surface area. The film material accumulated in the recess leads to an increase in the film thickness in the inner region (25i) of the weld seam (6, 7, 8). As a result, the mechanical stability of the medical pack formed as a bag can be improved.Type: GrantFiled: September 24, 2019Date of Patent: November 15, 2022Assignee: Fresenius Kabi Deutschland GmbHInventors: Joern Wittorf, Gerald Wegner, Tobias Lenhardt
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Patent number: 11464893Abstract: An apparatus includes a blood-flow-management assembly shaped to define a cylindrical aperture. The blood-flow-management assembly includes a blood collector having drainage holes configured to direct blood to a guide surface positioned below the blood collector. The guide surface may further include ribs that manage blood flow along the guide surface.Type: GrantFiled: February 29, 2016Date of Patent: October 11, 2022Assignee: Sorin Group Italia S.r.l.Inventors: Clara Pandolfini, Francesco Benatti, Claudio Silvestri
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Patent number: 11446426Abstract: A collapsible liquid reservoir has a flexible side wall having a lower step, a middle step and an upper step. Each of the steps includes a riser segment and a tread segment. The riser and tread segments are pivotably connected to one another at an external hinge. When the step is collapsed its segments define an acute step angle between them of about 23°. When the step is expanded its segments define an obtuse step angle between them of about 115°. The tread of at least one step is pivotably connected to the riser of an adjacent step at an internal hinge. The step segments joined to the internal hinge are symmetrical about a bisector of that hinge. The reservoir has a truncated pyramid shape defined by a generally square base and four trapezoidal side panels joined to one another at corners.Type: GrantFiled: June 26, 2018Date of Patent: September 20, 2022Assignee: Hollister IncorporatedInventors: Jerome Anthony Henry, William Kirwan Arnold, Denise Gamblin, Keith Hobert Gausmann, Maitreyee Mittal, Scott Eric Liddle, Anthony Scott Culbreth
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Patent number: 11357911Abstract: A multi-medicament infusion system (10) for preventing the mischanneling of medicaments may include an infusion pump (12), medicament reservoirs (16A,16B), a multi-channel lumen (18), and an infusion set (20). The medicament reservoirs may be sized and shaped differently such that the medicament reservoirs can only be inserted into the infusion pump in a unique configuration. The multi-channel lumen may include connectors that mate to corresponding connectors on the infusion pump and the infusion set only in a unique configuration. Because the various parts of the multi-infusion system may only be connected in the unique configuration, the expected medicaments may be administered appropriately and channeled to the correct infusion sites.Type: GrantFiled: December 15, 2020Date of Patent: June 14, 2022Assignee: Trustees of Boston UniversityInventors: Edward R. Damiano, Kirk D. Ramey, Firas H. El-Khatib
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Patent number: 11285504Abstract: An ejector device for ejecting droplets of fluid onto a surface includes an ejector mechanism attached to a fluid reservoir through a fluid loading plate that is configured to pierce the reservoir and channel the fluid to a rear surface of the ejector mechanism by capillary action. The ejector mechanism may have a centro-symmetric configuration with a lead free piezo actuator and may be covered by an auto-closing cover.Type: GrantFiled: June 29, 2016Date of Patent: March 29, 2022Assignee: Eyenovia, Inc.Inventors: Jonathan Ryan Wilkerson, Iyam Lynch, Charles Eric Hunter, Joshua Richard Brown, Louis Thomas Germinario, James Thornhill Leath, Nathan R. Faulks, Kris Grube, Matthew Ditrolio, J. Sid Clements
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Patent number: 11160728Abstract: A container for blood or a blood component is provided, the container comprising one or more container walls defining an interior chamber, the container walls comprising one or more layers, the layers comprising or consisting of a composition comprising one or more polymeric materials and at least one extractable agent selected from the group consisting of a terephthalate ester, a cyclohexane dicarboxylic acid ester, a citrate ester, and a polyol ester, wherein the container further comprises one or more additional components, wherein the container comprises less than about 3% (w/w) of di-2-ethylhexyl phthalate (DEHP), preferably wherein the container comprises less than about 3% (w/w) of phthalates. Thereby, improved blood products are provided in which the DEHP or overall phthalate content is reduced.Type: GrantFiled: December 17, 2014Date of Patent: November 2, 2021Assignee: Fresenius Kabi Deutschland GmbHInventors: Karin Platenkamp, Craig L. Sandford, Koos Hakvoort
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Patent number: 11154412Abstract: A medical device system may include an elongate shaft having a lumen extending from a proximal end to a distal end, a release wire disposed within the lumen of the elongate shaft configured to releasably attach a medical device to the distal end of the elongate shaft, and a securement member fixedly attached to the proximal end of the elongate shaft and to a proximal end of the release wire. A proximal portion of the securement member may be configured to translate proximally away from the proximal end of the elongate shaft upon application of a proximally-directed force to the proximal portion of the securement member while the elongate shaft is maintained in a fixed position, wherein the proximal portion remains connected to the proximal end of the elongate shaft after proximal translation away from the proximal end of the elongate shaft.Type: GrantFiled: February 1, 2019Date of Patent: October 26, 2021Assignee: Boston Scientific Scimed, Inc.Inventors: Nicholas Lee Tassoni, Eric Dinges, Kevin McConnell
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Patent number: 11110248Abstract: A medical device system may include an elongate shaft having a lumen extending from a proximal end of the elongate shaft to a distal end of the elongate shaft, a medical device disposed proximate the distal end of the elongate shaft, a release wire disposed within the lumen of the elongate shaft, wherein the release wire releasably secures the medical device to the distal end of the elongate shaft, a securement member fixedly attached to the proximal end of the elongate shaft and to a proximal end of the release wire, and a microcatheter configured to deliver the medical device to a treatment site, the elongate shaft and the medical device being slidably disposed within a lumen of the microcatheter. A proximal portion of the securement member may be configured to disengage from a distal portion of the securement member.Type: GrantFiled: November 15, 2017Date of Patent: September 7, 2021Assignee: Boston Scientific Scimed, Inc.Inventors: Gary J. Pederson, Jr., Mary-Claire Anderson, Ken Xiao Kang Zhang, David D. Groneberg, Nicholas L. Tassoni
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Patent number: 11077247Abstract: An intravenous tubing set is provided having a coupling component for accessing a source of flush solution; a flush chamber; a first IV tubing for delivering saline solution from the source of flush solution to the flush chamber; a first flow control device disposed in the tubing between the source of flush solution and the flush chamber to control the flow of flush solution into the flush chamber; a second IV tubing for delivering flush solution to a patient catheter; and a second flow control device disposed in the second tubing between the flush chamber and the patient catheter.Type: GrantFiled: April 10, 2019Date of Patent: August 3, 2021Assignee: Becton, Dickinson and CompanyInventors: Kathleen Wiest, Lindsay Miller, Jessica Williams, Rebecca Zaunbrecher, Ann Saterbak, Z. Maria Oden, Andrew Geiszler
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Patent number: 11059638Abstract: A container has an at least partially filled container body and at least one cap part (10). The cap part has at least one sealing part (16) that, for removal of the container contents, can be penetrated by a hollow-spike-shaped insertion part (22) from the outside, with a predeterminable actuating force, in an introduction direction. The insertion part can be removed from the container again, with a predeterminable pull-out force, in an oppositely directed pull-out direction. A device (16, 18) makes it difficult for the insertion part (22) to be removed with the pull-out force being increased such that unintentional removal of the insertion part (22) is at least made difficult.Type: GrantFiled: December 13, 2017Date of Patent: July 13, 2021Assignee: KOCHER-PLASTIK MASCHINENBAU GMBHInventors: Michael Spallek, Johannes Geser, Philipp Spreng
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Patent number: 11052233Abstract: A tube for a medical container has a tube wall which consists of at least two layers. According to the invention, at least one layer contains a styrene-containing thermoplastic polymer (S-TPE), in particular a styrene-butadiene block copolymer (SBC) or a copolyester, a copolyester ether or a cyclic olefin copolyester. The at least one other layer contains ethylene-vinyl acetate copolymer (EVA), preferably with a vinyl acetate (VA) portion in the ethylene-vinyl acetate copolymer of from 10% to 30%, preferably 14% to 28%. The EVA can be mixed with a thermoplastic polybutene and/or SEBS to improve the tube properties. The tube wall can have a two-layer structure with an inner or an outer layer which contains the S-TPE, copolyester, copolyester ether or cyclic olefin copolyester, or a three-layer structure with an outer and inner layer containing the S-TPE or copolyester or copolyester ether.Type: GrantFiled: October 13, 2017Date of Patent: July 6, 2021Assignees: N.V. Nutricia, RaumedicAGInventors: Reinhold Wolkenstoerfer, Ralf Ziembinski
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Patent number: 10874789Abstract: An assembly for adding a medication or like substance to a liquid solution in a flexible bag (10) is provided. The flexible bag (10) contains a liquid solution, such as dialysate. An adapter (14) extends from the flexible bag (10) and includes a skirt (20) having an array of resilient sections (22) for engaging and snapping onto a neck finish (106) of a separate vial (100) containing a medication or like substance. A locking device (16) is adapted to be secured about the skirt (20) in a locking position that prevents outward movement of the array of resilient sections (22) and thereby prevents disengagement of the vial (100) from the adapter (14). A method of transferring the liquid solution from the bag (10) to the vial (100), mixing the medication with the liquid solution, and returning the mixture to the bag (10) is also provided.Type: GrantFiled: December 2, 2016Date of Patent: December 29, 2020Assignees: DREXEL UNIVERSITY, NEW YORK UNIVERSITYInventors: Jeffrey John Cies, Arun Chopra, Moses Noh
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Patent number: 10780244Abstract: A urinary catheter set includes a urine collection bag formed into an outer packaging for the urinary catheter set, and a urinary catheter positioned inside of the urine collection bag.Type: GrantFiled: January 12, 2018Date of Patent: September 22, 2020Assignee: Rochester Medical Corporation, a subsidiary of C. R. Bard, Inc.Inventors: Anthony J. Conway, Sarah L. Grinde
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Patent number: 10603878Abstract: An optical layered body including: a substrate layer formed of a resin containing a crystallizable polymer A; and a first surface layer formed of a resin containing an amorphous polymer B, wherein a glass transition temperature TgA of the crystallizable polymer A and a glass transition temperature TgB of the amorphous polymer B satisfy TgB>TgA, a crystallization temperature TcA of the crystallizable polymer A and the glass transition temperature TgB of the amorphous polymer B satisfy TcA?10° C.?TgB?TcA?60° C., the first surface layer has a plane orientation coefficient P that satisfies P?0.01, and a ratio of a thickness of the substrate layer relative to a total thickness of the optical layered body is 25% or more.Type: GrantFiled: December 27, 2016Date of Patent: March 31, 2020Assignee: ZEON CORPORATIONInventor: Kyosuke Inoue
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Patent number: 10399844Abstract: An insert for use with a flexible liquid bag, having upper and lower ends, with the upper end of the bag having a hollow support structure with open upper and lower ends, mounted in an opening formed in the bag adjacent the upper end of the bag. The insert has open upper and lower ends with the lower end of the insert being received by the open upper end of the hollow support structure. A normally closed valve structure is positioned in the insert to prevent liquid from flowing therethrough. An actuator cap is threadably mounted on the upper end of the insert. The actuator cap includes structure to open the normally closed valve so that liquid in the bag may flow through the insert. The bag with the insert secured thereto will be inverted in use so that the liquid will flow downwardly from the bag.Type: GrantFiled: March 27, 2017Date of Patent: September 3, 2019Inventor: Rodney Laible
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Patent number: 10398625Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.Type: GrantFiled: March 13, 2013Date of Patent: September 3, 2019Assignee: FENWAL, INC.Inventors: Craig Sandford, Yoshikazu Mizobuchi, Daniel Lynn
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Patent number: 10400212Abstract: This invention concerns methods of packaging and shipping stem cells. Also disclosed are related package products.Type: GrantFiled: April 23, 2018Date of Patent: September 3, 2019Assignee: Stemcyte Inc.Inventors: Wise Young, Dongming Sun, Robert Fleischaker, Kam Sze Kent Tsang
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Patent number: 10293106Abstract: An intravenous tubing set is provided having a coupling component for accessing a source of flush solution; a flush chamber; a first IV tubing for delivering saline solution from the source of flush solution to the flush chamber; a first flow control device disposed in the tubing between the source of flush solution and the flush chamber to control the flow of flush solution into the flush chamber; a second IV tubing for delivering flush solution to a patient catheter; and a second flow control device disposed in the second tubing between the flush chamber and the patient catheter.Type: GrantFiled: March 31, 2014Date of Patent: May 21, 2019Assignee: Becton, Dickinson and CompanyInventors: Kathleen Wiest, Lindsay Miller, Jessica Williams, Rebecca Zaunbrecher, Ann Saterbak, Z. Maria Oden, Andrew Geiszler
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Patent number: 10195113Abstract: A needle-free adaptor for removing liquid from a vial comprises a cannula adapted to piece a septum of a vial, a plurality of legs surrounding the cannula to secure the adaptor to the vial when the cannula has pieced the septum, an elastomeric membrane having a normally closed pinhole orifice, and a conforming surface having an orifice connected to the cannula. The elastomeric membrane has a stable convex shape and is adapted to receive a nozzle of a needle-free device. Pressed against the elastomeric membrane, the nozzle deflects the elastomeric membrane from the convex shape to an unstable or pseudo-stable inverted position against the conforming surface. Buckling of the elastomeric membrane opens the pinhole orifice and enables fluid communication between the vial and the nozzle by interfacing the pinhole orifice with the orifice on the conforming surface.Type: GrantFiled: April 29, 2015Date of Patent: February 5, 2019Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Ashin P. Modak, Nora Catherine Hogan
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Patent number: 10159790Abstract: A fluid infusion system includes an air pump connected to an accumulator tank to produce pressurized air that is stored in the accumulator tank. The system can include one or more fluid bag chambers wherein each fluid bag chamber includes an inflatable bladder positioned inside the fluid bag chamber to apply pressure on the fluid bag supported inside the chamber. The fluid bag can be connected by a tube set to deliver fluid from the fluid bag to a surgical tool at a surgical site. The fluid can, for example, be irrigation fluid or distention fluid. The system can include a controller connected to the pump to control the pump to produce the pressurized air and an adjustable pressure regulator can be connected between the accumulator tank and the inflatable bladder to control the pressure of air delivered to the inflatable bladder and the pressure that the fluid is delivered to the surgical tool.Type: GrantFiled: June 30, 2016Date of Patent: December 25, 2018Assignee: IBT INCORPORATEDInventors: Peter Boyle, Keith Isaacson, Seth Traub, Craig Traub
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Patent number: 10023672Abstract: Provided is a process of making a polyphenylene oxide prepolymer, comprising a step of reacting a reactive cycloolefin and a vinyl-containing polyphenylene oxide in the presence of a ruthenium catalyst. The reactive cycloolefin may be selected from dicyclopentadiene monomer, dicyclopentadiene oligomer, dicyclopentadiene polymer, norbornene monomer, norbornene oligomer, norbornene polymer, and a combination thereof; the vinyl-containing polyphenylene oxide may be selected from divinylbenzyl polyphenylene oxide resin, vinylbenzyl-modified polyphenylene oxide resin, methacrylic polyphenylene oxide resin, and a combination thereof; the ruthenium catalyst may be a Grubbs catalyst. Also provided are a polyphenylene oxide prepolymer made by the process, a resin composition containing the polyphenylene oxide prepolymer, and a product made from the resin composition.Type: GrantFiled: November 16, 2016Date of Patent: July 17, 2018Assignee: ELITE MATERIAL CO., LTD.Inventor: Chen-Yu Hsieh
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Patent number: 9999570Abstract: A fluid transfer system includes a container having a body having a sidewall extending between an open top end and a bottom end along a central axis to define an interior cavity, and at least one protrusion extending from an interior portion of the sidewall into the interior cavity. The system further including a connector configured for receipt within the interior cavity. The connector having a body having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end and defining a fluid passageway therethrough, and a locking arrangement provided on at least a portion of an inner member of the connector and accessible through at least a portion of an outer member of the connector. The locking arrangement is configured for cooperating with the at least one protrusion to prevent rotation of the inner member relative to the outer member.Type: GrantFiled: April 21, 2015Date of Patent: June 19, 2018Assignee: Becton Dickinson and Company LimitedInventors: Laurie Sanders, Jayeon Kim
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Patent number: 9907726Abstract: An injection bag is formed of a multilayer film, and includes an intermediate layer that includes a mixture of 60 to 90 mass % of a crystalline polyamide resin and 10 to 40 mass % of a noncrystalline polyamide resin. The crystalline polyamide resin has a combined content of a monomer and a low-molecular-weight polymer of 0.8 mass % or less. The noncrystalline polyamide resin includes a semi-aromatic polyamide.Type: GrantFiled: April 3, 2014Date of Patent: March 6, 2018Assignees: Kewpie Kabushiki Kaisha, Baxter International Inc.Inventors: Yoshikazu Ishino, Zenichiro Kai, Koji Sueyoshi, Ken Watanabe
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Patent number: 9833941Abstract: A mold (11) for manufacturing a container (2) having a body (4) and a bottom (6), including: an annular peripheral base (8) defining a positioning plane (9); an arch (10) which extends concavely toward the inside of the container (2) from the base (8), the mold (11) including: a wall (12) having an inner surface (13) forming the cavity of the body (4) of the container (2) and having an opening therethrough, the wall (12) having an edge (23) forming the cavity of the positioning plane (9); a mold bottom (14) which is moveably mounted relative to the wall (12), the mold bottom (14) having an upper surface (15) forming the cavity of the arch (10), and a skirt (19) having an outer radial extension that is strictly lower than an inner radial extension of the positioning plane (9).Type: GrantFiled: April 8, 2014Date of Patent: December 5, 2017Assignee: SIDEL PARTICIPATIONSInventors: Laurent Penet, Pierrick Protais, Michel Boukobza
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Patent number: 9833605Abstract: A fluid transfer system includes packaging having a body with a sidewall extending between an open top end and a bottom end and defining an interior cavity, and at least one protrusion extending radially inward from the sidewall into the interior cavity. The system also includes a fluid transfer device including an inner member and an outer member surrounding at least a portion of the inner member. The inner member having a first position where the inner member is configured to rotate freely relative to the outer member and a second position where rotation of the inner member relative to the outer member is restricted in a first rotational direction. The fluid transfer device also including a locking arrangement configured for cooperating with the at least one protrusion to prevent rotation of the inner member relative to the outer member upon an application of a compressive force on the packaging.Type: GrantFiled: April 21, 2015Date of Patent: December 5, 2017Assignee: Becton Dickinson and Company LimitedInventors: Laurie Sanders, Jayeon Kim
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Patent number: 9828488Abstract: PURPOSE: The present invention provides a polyvinyl chloride resin composition which is superior in heat stability and processability and has less elution from the composition. CONSTITUTION: a polyvinyl chloride resin composition comprising 100 parts by weight of a polyvinyl chloride resin, 10 to 120 parts by weight of di(2-ethylhexyl)terephthalate, and 0.5 to 20 parts by weight of epoxidized vegetable oil having a peroxide number of 5 or less.Type: GrantFiled: August 3, 2016Date of Patent: November 28, 2017Assignee: RIKEN TECHNOS CORPORATIONInventor: Koji Sakai
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Patent number: 9816901Abstract: The invention relates to a liquid sample preparation device such as a disposable, collapsible, flexible polymeric bag containing an adsorptive curtain of a functionalized shaped polymeric fiber bed for the direct capture of biomolecules from liquid samples. The functionalized shaped polymeric fiber bed includes fibrillated, ridged or winged-shaped fiber structures that significantly increases the surface area of the fiber resulting in enhanced separation, retention and/or purification of liquid samples containing biomolecules of interest as the liquid samples contact the adsorptive curtain of functionalized shaped fibers. Liquid samples include unclarified liquid feeds or other liquids containing one or more biomolecules of interest, including, but not limited to vaccines, recombinant proteins, cells, stem cells, monoclonal antibodies (mAbs), proteins, antibody, peptides, oligopeptides, nucleic acids, oligonucleotides, RNA, DNA, oligosaccharides and polysaccharides.Type: GrantFiled: December 13, 2013Date of Patent: November 14, 2017Assignee: EMD Millipore CorporationInventor: Benjamin Cacace
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Patent number: 9789301Abstract: A flow control clamp having a first member and a second member movable from a first open position to a second irreversibly closed position wherein flow through a tube associated with the clamp is irreversibly prevented and cannot be restored. Systems and methods using such clamps are also disclosed.Type: GrantFiled: October 19, 2016Date of Patent: October 17, 2017Assignee: Fenwal, Inc.Inventors: Jean-Marie Mathias, Gianni DiStefani
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Patent number: 9603965Abstract: The disclosed invention provides a system and method of artificially retarding fibrin-based blood clot degradation via the sustained release of a protease inhibitor, such as, for example, aprotinin or tranexamic acid (“TA”). The sustained release of the protease inhibitor is accomplished through incorporation within a biodegradable polymer microsphere to produce a protease inhibitor formulation. Next, the formulation along with fibrinogen and thrombin is applied to a wound site where an outer surface of the polymer microsphere degrades in a proteolytic environment to expose and release the incorporated protease inhibitor to the surrounding hydrogel or sealant or clot matrix at the wound site.Type: GrantFiled: December 10, 2015Date of Patent: March 28, 2017Assignee: Bordoloi Biotech, LLCInventors: Binoy K Bordoloi, Nayan J Sarma, Rodney L. Eisenberg
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Patent number: 9199016Abstract: A system and methodology for the preservation of red blood cells is described in which red blood cells are oxygen or oxygen and carbon dioxide depleted, treated and are stored in an anaerobic environment to optimize preparation for transfusion. More particularly, a system and method for extended storage of red blood cells from collection to transfusion that optimizes red blood cells prior to transfusion is described.Type: GrantFiled: July 3, 2012Date of Patent: December 1, 2015Assignee: New Health Sciences, Inc.Inventors: Tatsuro Yoshida, Paul Vernucci
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Patent number: 9180246Abstract: The apparatus relates to a medicament container for a liquid medicament. The medicament container comprises a deformable bag with an outlet and at least one deformation member consisting of a shape memory alloy. The at least one deformation member is arranged to deform the deformable bag when the shape memory alloy passes from a first phase into a second phase by a phase transition, thereby changing the shape of the deformation member and squeezing a dose of the medicament through the outlet out of the bag.Type: GrantFiled: September 8, 2010Date of Patent: November 10, 2015Assignee: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Thomas Nagel, René Richter, Robert Witt