Blood Collection Container Patents (Class 604/6.15)
  • Patent number: 7845499
    Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: December 7, 2010
    Assignee: Biomet Biologics, LLC
    Inventors: Joel C. Higgins, Matthew Swift, Nathan Gordon, Barry F. Hecker
  • Publication number: 20100292628
    Abstract: A fluid cassette for a blood processing system includes a cassette housing and a rigid structure. The cassette housing defines the structure of the cassette and has a fluid path at least partially extending through it. The fluid path is configured to allow a fluid to pass through the housing. The rigid structure defines a cavity that is in fluid communication with the fluid path. The rigid structure also has an interface for interfacing and/or connecting with a pressure monitoring device. The interface allows the pressure monitoring device to measure the pressure within the fluid path. The cavity has a volume of air located between the fluid path and the interface.
    Type: Application
    Filed: May 13, 2009
    Publication date: November 18, 2010
    Applicant: HAEMONETICS CORPORATION
    Inventors: Edward T. Powers, Matthew J. Murphy, Michael Ragusa
  • Patent number: 7832566
    Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample and mesenchymal stem cells from bone reaming material. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: November 16, 2010
    Assignee: Biomet Biologics, LLC
    Inventors: Michael D. Leach, Joel C. Higgins, Matthew Swift, Nathan Gordon
  • Patent number: 7824343
    Abstract: Methods and apparatus for collecting blood samples in vacuum sample tubes are disclosed. The samples, including the initial blood sample, are substantially free of excess air.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: November 2, 2010
    Assignee: Fenwal, Inc.
    Inventors: Jean-Marie Mathias, Bryan Blickhan, Stephanie Haldiman, Larry Servi, Jr., Jean-Claude Bernes, Daniel F. Bischof
  • Patent number: 7824356
    Abstract: A system is disclosed for removing gas bubbles from blood during circulatory assist procedures. Such bubbles are generated, along with particulate matter, in an extracorporeal circulatory bypass system by the pump, oxygenator and other components. Filters are used in the line to remove particulates and bubbles from the blood before they are pumped back to the patient but current filters are inefficient at removing small bubbles and debris that can cause neurological defects and renal and other organ failures in the patient. An active filter apparatus and method is disclosed that forces the bubbles to the center of the system where they are removed from the blood before the blood exits the filter. The filter comprises an axially elongate cylindrical shell with a blood inlet, a blood outlet and a gas outlet.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: November 2, 2010
    Assignee: Indian Wells Medical, Inc.
    Inventors: David W. Wieting, Jay A. Lenker
  • Patent number: 7820102
    Abstract: A device generates a gas-enriched physiologic fluid and combines it with a bodily fluid to create a gas-enriched bodily fluid. The device may take the form of a disposable cartridge. The cartridge may include a fluid supply chamber for delivering physiologic fluid under pressure to an atomizer. The atomizer delivers fluid droplets into a gas-pressurized atomization chamber to enrich the physiologic fluid with the gas. The gas-enriched physiologic fluid is delivered to a mixing chamber in the cartridge where the gas-enriched physiologic fluid is mixed with a bodily fluid, such as blood, to create a gas-enriched bodily fluid.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: October 26, 2010
    Assignee: TherOx, Inc.
    Inventors: Stephen E. Myrick, Gregory P. Watson, William R. Patterson, Paul J. Zalesky
  • Publication number: 20100268148
    Abstract: A cardiotomy and venous blood reservoir, including a housing assembly, a venous inlet port, a venous sub-assembly, a cardiotomy inlet port, and a cardiotomy sub-assembly. The housing forms a chamber. The venous sub-assembly includes a downtube and a bowl. A diameter of the downtube lumen increases to a downstream end. The bowl forms a floor surface for receiving flow from the lumen. The cardiotomy sub-assembly includes a dish and an inner post. The dish defines an aperture. The inner post extends from the dish and forms a guide surface received within the central aperture and forming an undulating curvature increasing to a diameter greater than the diameter of the central aperture. Cardiotomy liquid drops from the dish fall on to the undulating, closely positioned guide surface with minimal splashing.
    Type: Application
    Filed: April 30, 2010
    Publication date: October 21, 2010
    Applicant: Medtronic, Inc.
    Inventors: Mark E. Wendler, Ana R. Menk, Eric R. Fox, Ningze Sun, Timothy D. Groen, Katherine S. Olig
  • Patent number: 7789847
    Abstract: A method and apparatus for red blood collection and filtration is provided wherein a red blood cell collection assembly provides for leukoreduction filtration concurrent with or soon after the red blood cell separation and collection procedure. Such procedures involve filtering the separated red blood cells in a diluted state after and/or prior to flushing the filter with storage solution. Storage solution may thus be passed through the leukoreduction filter before, with and/or after the RBCs have been filtered therethrough. The red blood cell collection, filtration and storage assembly is preferably preconnected to a blood component separation disposable assembly, including, for example, a centrifuge vessel and a blood removal/return assembly for removing blood from a donor, passing the blood to the centrifuge vessel for separation of the blood into components for collection and providing for filtration of the separated red blood cell component.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: September 7, 2010
    Assignee: CaridianBCT, Inc.
    Inventors: Bruce W. Gibbs, Jon Herskovits
  • Patent number: 7780860
    Abstract: An apparatus is disclosed that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: August 24, 2010
    Assignee: Biomet Biologics, LLC
    Inventors: Joel C. Higgins, Michael D. Leach, Jennifer E. Woodell-May, Brandon Miller
  • Patent number: 7780621
    Abstract: A blood chamber for an extracorporeal blood circuit comprises a blood inlet port (2), a blood containment chamber (3), a first conduit (8) which connects the blood inlet port (2) with the blood containment chamber (3) and which has an end tract (8a) that terminates in the blood containment chamber (3) with a horizontal inlet component. The first conduit (8) comprises a pre-terminal tract (8b) which precedes the end tract (8a) and which has at least a second horizontal component which is directed in an opposite direction to the horizontal inlet component. The blood chamber is used in an arterial line of a dialysis set for guaranteeing a regular and gentle blood flow.
    Type: Grant
    Filed: July 6, 2005
    Date of Patent: August 24, 2010
    Assignee: Gambro Lundia AB
    Inventors: Robert Neri, Andrea Paltrinieri
  • Patent number: 7766900
    Abstract: A method and apparatus for separation, concentration, and/or applying a biological or bio-engineered fluid. Generally, the fluid application device includes a sprayer body to enable the application of the fluid and a container adaptable to enable the separation of the fluid into at least a first component and a second component. The container is releasably coupled to the nozzle. The nozzle is adapted to withdraw at least one of the first component or the second component from the container after the fluid has been separated to apply the fluid to a selected site.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: August 3, 2010
    Assignee: Biomet Manufacturing Corp.
    Inventors: Michael D Leach, Barry F Hecker
  • Patent number: 7766854
    Abstract: A biological fluid collection system including a collecting device, a collecting container, a first channel connecting the two, a sampling bag, a second channel connecting the sampling bag and the first tube and at least one substantially irreversible closure device in an open position on at least the first or second channel. The biological fluid may be blood. A method of collecting biological fluid such as blood using the system so that fluid in the sampling bag is substantially irreversibly prevented from entering the collecting container.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: August 3, 2010
    Assignee: MacoPharma
    Inventors: Francis Goudaliez, Thierry Verpoort
  • Patent number: 7762976
    Abstract: An apparatus for extracorporeal oxygenation of a patient's blood during cardiopulmonary bypass surgery. The apparatus comprises a bubble sensor, arranged at or connected to a venous line, for detecting bubbles in the venous blood received from the patient. When air bubbles are detected, a second pump is activated to draw air from an air chamber provided in an air filter connected to the venous line and arranged downstream of the bubble sensor. A first pump draws the blood from the air filter and supplies the blood to an oxygenator and to the patient via an arterial line.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: July 27, 2010
    Assignee: Sorin Group Deutschland GmbH
    Inventors: Johann Schreyer, Erwin Knott, Andreas Hahn
  • Patent number: 7758517
    Abstract: A sensor and a lancet are integrated with each other. A thin strip-shaped sensor and a lancet are integrated so that the lancet moves in parallel, along a longitudinal direction of the sensor. A measuring device to which an integrated lancet and sensor is attached is provided with a function of driving the attached lancet.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: July 20, 2010
    Assignee: Panasonic Corporation
    Inventors: Shinichi Kojima, Yoshinobu Tokuno
  • Publication number: 20100179467
    Abstract: The present invention relates to a device for controlling a system for transporting blood, and a method for transporting blood in a blood line of an extracorporeal blood circuit of an extracorporeal blood treatment system. The present invention also relates to an extracorporeal blood treatment device comprising such a system for transporting blood. The method and device according to the present invention are based on the fact that a defined threshold value for the pressure in the blood line should not be exceeded. The system for transporting blood is controlled in such a way the blood in the blood line is transported in a pre-determined volume flow as long as the pressure in the blood line is below the pre-determined threshold value. When the pressure in the blood line reaches the pre-defined threshold value, however, the system for transporting blood is controlled such that a pressure value corresponding to the threshold value is set when the blood is transported in the blood line.
    Type: Application
    Filed: May 31, 2008
    Publication date: July 15, 2010
    Inventors: Götz Günther, Michael Herrenbauer, Martin Lauer, Ralf Müller
  • Publication number: 20100137778
    Abstract: An automated blood sampler integratable with a glucose monitor comprises a catheter connected to a tube-set forming a single blood passageway; a clamp-on air-bubble sensor and a occlusion sensor externally attached to the tube set; a single peristaltic pump and two 3-way pinch valves attached to the tube set and control fluid flow. The sampler draws blood from a stationary patient, samples the blood for analytical measurement of blood parameters; after which the passageway is rinsed, the blood re-infused, and slow saline infusion prevents vein collapse. The cycle repeats at user or predefined intervals. In another preferred embodiment, blood is not re-infused, and only one 3-way pinch valve is used.
    Type: Application
    Filed: December 2, 2008
    Publication date: June 3, 2010
    Inventors: Kislaya Kunjan, Frank P. Lloyd, JR.
  • Publication number: 20100125236
    Abstract: Apparatus and methods for producing interleukin-1 receptor antagonist and/or other prophylatically or therapeutically effective protein. Blood is obtained from a patient with a conventional syringe and then introduced into dual luer lock centrifuge tube. The dual luer lock centrifuge tube is provided with beads that are coated with a silanized coating. The container is then incubated and centrifuged. Subsequent to the incubation and the centrifugation, the serum containing autologous therapeutically active protein, such as IL-1Ra, in the container is withdrawn through the luer lock of the container, and injected back into the patient.
    Type: Application
    Filed: November 10, 2009
    Publication date: May 20, 2010
    Inventors: Christopher Bare, David O. Shepard
  • Patent number: 7717897
    Abstract: A flexible non-PVC, non-DEHP polyolefin container or bag for medical fluids has an elongated container body formed of polyolefin film. The container has one or more ports equipped with a polyolefin fill tube and port closure assembly. The container includes a concave seam on at least one of its longitudinal sides.
    Type: Grant
    Filed: July 31, 2006
    Date of Patent: May 18, 2010
    Assignee: Hospira, Inc.
    Inventors: Richard E. Burg, Martin H. Roskres, George M. Ramsay, Mark I. Ostler, Marc M. Daniels, Mary Beth Baker
  • Publication number: 20100114005
    Abstract: In an apparatus for extracorporeal blood treatment, an extracorporeal circuit (6) is connected to a blood chamber (3) of a membrane device (2). A pump (10) displaces a priming fluid from a source of a priming fluid (9) to a drainage (11) for discharging the priming fluid. A control unit (13) is provided with a processor which controls the pump at a preset first flow rate value, and receives from a pressure sensor (12) a first pressure value, compares the first pressure value with a reference pressure value and, on the basis of this comparison, determines whether or not the extracorporeal circuit is of a pediatric type or of an adult type. The invention is particularly useful during a stage of readying a dialysis apparatus.
    Type: Application
    Filed: April 12, 2007
    Publication date: May 6, 2010
    Applicant: GAMBRO LUNDIA AB
    Inventor: Paolo Rovatti
  • Patent number: 7708710
    Abstract: Methods are disclosed for collecting and separating whole blood into one or more components. A disposable blood separation fluid circuit is provided which is adapted to cooperate with a reusable separation controller. The fluid circuit includes a fluid flow path for communication with a blood source and at least one container in fluid communication with the fluid flow path. The fluid flow path is connected to a blood source and quantities of whole blood are collected in the container and one other location within the fluid circuit. The source is then disconnected from the disposable fluid circuit. The quantities of whole blood are centrifugally processed, with processing of at least a portion of one of the quantities beginning after the source is disconnected from the fluid circuit.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: May 4, 2010
    Assignee: Fenwal, Inc.
    Inventors: Kyungyoon Min, Richard I. Brown
  • Patent number: 7691071
    Abstract: A sensor and a lancet are integrated with each other. A thin strip-shaped sensor and a lancet are integrated so that the lancet moves in parallel, along a longitudinal direction of the sensor. A measuring device to which an integrated lancet and sensor is attached is provided with a function of driving the attached lancet.
    Type: Grant
    Filed: January 21, 2002
    Date of Patent: April 6, 2010
    Assignee: Panasonic Corporation
    Inventors: Shinichi Kojima, Yoshinobu Tokuno
  • Patent number: 7686777
    Abstract: An in-vitro blood plasma lipids filtering method includes the following steps: separating out the blood plasma from the blood collection; flushing a filtering device with saline solution; controlling the pressure of the separated blood plasma; passing the blood plasma to the filtering device for filtering out lipids; controlling the temperature of the filtered blood plasma; and feeding the blood plasma back to the blood. The method is clearly effective and accurate, quick response indication, securer and safer, more tolerant, and the treatment time is short.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: March 30, 2010
    Assignee: Shanghai Jiangxia Blood Technology Co., Ltd.
    Inventors: Heping Huang, Siukwan Chang
  • Patent number: 7682329
    Abstract: A method and apparatus for red blood collection and filtration is provided wherein a red blood cell collection assembly provides for leukoreduction filtration concurrent with or soon after the red blood cell separation and collection procedure. Such procedures involve filtering the separated red blood cells in a diluted state after and/or prior to flushing the filter with storage solution. Storage solution may thus be passed through the leukoreduction filter before, with and/or after the RBCs have been filtered therethrough. The red blood cell collection, filtration and storage assembly is preferably preconnected to a blood component separation disposable assembly, including, for example, a centrifuge vessel and a blood removal/return assembly for removing blood from a donor, passing the blood to the centrifuge vessel for separation of the blood into components for collection and providing for filtration of the separated red blood cell component.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: March 23, 2010
    Assignee: CaridianBCT, Inc.
    Inventors: Bruce W. Gibbs, Jon Herskovits
  • Patent number: 7666159
    Abstract: A venous reservoir in an extracorporeal blood circuit, comprising a rigid outer enclosure for a filtering mass in the form of a hollow cylinder, provided with an upper lid which comprises couplings for the inflow of blood with the portion of space delimited by the filtering mass and with a connector at the bottom, the reservoir further comprising a diaphragm which is arranged below the upper lid and is adapted to receive the blood that enters through the couplings provided in the peripheral region of the lid, at the axis of a central hole of the diaphragm there is a column with longitudinal vanes which protrude upwardly until they skim the rim of the hole and are adapted to follow the blood in its flow by gravity toward the collection region at the base of the enclosure.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: February 23, 2010
    Assignee: Eurosets S.r.l.
    Inventors: Nicola Ghelli, Edgardo Costa Maianti, Roberto Balanzoni
  • Publication number: 20100030125
    Abstract: The present invention consists of a blood reservoir that incorporates a separate chamber designed to trap condensing water vapor. The blood chamber and the vapor trap are in fluid communication along their top assuring that vacuum applied to the top of the vapor trap is equally applied to the blood chamber. The combination is also structured to prevent condensate water accumulating in the vapor trap chamber from overflowing into the blood chamber as well as provide a structure that allows the end user to empty the water in the vapor trap chamber.
    Type: Application
    Filed: September 20, 2009
    Publication date: February 4, 2010
    Inventor: Yehuda Tamari
  • Patent number: 7651473
    Abstract: The extracorporeal blood circulating apparatus of the present invention includes: a closed-type venous reservoir having a blood storage chamber and a volume adjusting chamber that are disposed adjacently by partitioning a closed space formed by a housing; an adjusting liquid tank for storing an adjusting liquid that is connected to the volume adjusting chamber; and a blood pump that is connected to the blood storage chamber. In the housing, an inflow port for allowing blood to inflow and an outflow port for allowing blood to outflow are provided so as to communicate with the blood storage chamber, and an adjusting port for injecting and ejecting the adjusting liquid is provided so as to communicate with the volume adjusting chamber. The blood pump is connected via the outflow port, and the adjusting liquid tank is connected via the adjusting port.
    Type: Grant
    Filed: December 8, 2004
    Date of Patent: January 26, 2010
    Assignee: JMS Co., Ltd.
    Inventors: Shigeki Kawarabata, Hiroyuki Maeda, Yutaka Nakahara
  • Patent number: 7651474
    Abstract: A method and apparatus for red blood collection and filtration is provided wherein a red blood cell collection assembly provides for leukoreduction filtration concurrent with or soon after the red blood cell collection procedure. The procedure preferably involves filtering the separated red blood cells in a high hematocrit (high-crit) state prior to addition of storage solution thereto. Preferably, a storage solution is passed through the leukoreduction filter after the RBCs have been filtered therethrough. The red blood cell collection filtration and storage assembly is preferably preconnected to a blood component separation disposable assembly, including, for example, a centrifuge vessel and a blood removal/return assembly for removing blood from a donor, passing the blood to the centrifuge vessel for separation of the blood into components for collection and providing for filtration of the separated red blood cell component, as described.
    Type: Grant
    Filed: June 3, 2004
    Date of Patent: January 26, 2010
    Assignee: CaridianBCT, Inc.
    Inventors: Geert Van Waeg, Bruce W. Gibbs, Marc Antoon, Laura Goodrich
  • Patent number: 7648639
    Abstract: A method for separating a volume of a composite liquid into at least a first component and a second component is performed in a centrifuge cooperating with a separation bag containing the volume of composite liquid. The separation bag is connected to at least a first component bag and a second component bag. The separation bag is spun so as to centrifuge the volume of composite liquid and cause the sedimentation of the at least first and second components. When the at least first and second components have sedimented, the first component is transferred at least one first transfer flow rate into the first component bag. When the first component has been transferred into the first component bag, the second component is transferred into the intermediate component bag at least one second transfer flow rate that is different from the at least one first transfer flow rate.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: January 19, 2010
    Assignee: CaridianBCT, Inc
    Inventors: Brian M. Holmes, Peter Pihlstedt, Geert Van Waeg
  • Patent number: 7621885
    Abstract: A set of units for a device integrated in an extracorporeal blood circuit, comprising a cardiotomy reservoir which is provided with elements adapted to provide a monolithic coupling selectively with identical complementary elements of a venous reservoir and a venous bag.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: November 24, 2009
    Assignee: Eurosets S.r.l.
    Inventors: Nicola Ghelli, Edgardo Costa Maianti, Roberto Balanzoni
  • Patent number: 7621884
    Abstract: A tube for medical applications comprises a chlorine-free material and has a layer defining an outer surface of the tube. The tube is manufactured from a polymer material having a solubility parameter within the range 9.9±1.5 (cal/cm3)1/2.
    Type: Grant
    Filed: March 7, 2003
    Date of Patent: November 24, 2009
    Assignee: Gambro Lundia AB
    Inventors: Hermann Goehl, Martin Hanna, Marcello Malagoli, Annalisa Delnevo
  • Publication number: 20090275875
    Abstract: The task was to create a multifunctional system for the extracorporeal circulation (ECC) for a heart-lung bypass, which primarily makes use of the advantages of a minimized ECC system, but which in the case of need at any time can also be used universally and at low risk as another closed and open ECC system. Besides, it shall provide the option of an automatic negative pressure and volume compensation when being used as minimized ECC system. According to the invention, a special reservoir (48), particularly a venous cardiotomy reservoir, for blood and/or priming solution is presented, which consists of a form-stable bottom part (57), wherein a level sensor (57) can be integrated, and a flexible part (56) located on top of it, which seeks to increase its volumetric capacity. The equipment is used in the artificial circulation of patients by the use of a heart-lung machine.
    Type: Application
    Filed: June 16, 2006
    Publication date: November 5, 2009
    Applicant: MAQUET CARDIOPULMONARY AG
    Inventors: Kai Liebing, Thorsten Wahlers, Mirko Kaluza
  • Patent number: 7611478
    Abstract: Continuous volume detection for a reservoir in a fluid circuit of a medical system is described. Volume detection is based on a pressure measurement that is manipulated via application of fluid mechanics. Next-generation medical system controllers may use this data to control the volume contained in the reservoir.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: November 3, 2009
    Assignee: Minnetronix Inc.
    Inventors: Lori E. Lucke, Matthew J. Cunningham, Richard A. Nazarian
  • Patent number: 7591812
    Abstract: The invention is a closed complaint venous reservoir with at least one pliable wall having at least three innovative features: 1) the venous reservoir incorporates means that purge gas bubbles entering the venous reservoir without the user intervention, 2) the venous reservoir incorporates a cardiotomy reservoir, and 3) the pliable wall of the venous reservoir is sealed within a rigid housing allowing control of its “atmospheric” pressure, and therefore the pressure at which that wall collapses. The combination of the three innovative features provides a collapsible compliant reservoir unitized with cardiotomy reservoir having air removal features and enabling vacuum augmented venous drainage (VAVD) that match that of the open hardshell venous-cardiotomy reservoir unit, while retaining the advantages of the closed soft shell venous reservoir.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: September 22, 2009
    Inventor: Yehuda Tamari
  • Patent number: 7588723
    Abstract: An input blood supply within a blood perfusion system is pumped through a chamber. A centrifugal flow of the input blood supply is formed in a bottom region of the chamber to cause air to migrate toward an axial center of the chamber. A float is buoyantly suspended on the centrifugal flow wherein the float is disposed for vertical movement in the chamber, and wherein the float has an effective density less than the density of the blood. When a volume of air present within the chamber is less than a predetermined volume, then the float closes a valve at an air outlet from the chamber. When a volume of air present within the chamber is greater than the predetermined volume, then the float opens the valve to remove air from the chamber.
    Type: Grant
    Filed: April 29, 2005
    Date of Patent: September 15, 2009
    Assignee: Terumo Cardiovascular Systems Corporation
    Inventor: Arthur D. Gershowitz
  • Publication number: 20090227931
    Abstract: Embodiments of the present application are directed to devices, systems and methods for irradiating fluids (e.g., blood) with ultraviolet light, and corresponding related components, systems and methods. In some embodiments of the invention, an ultraviolet blood irradiation (UBI) system is provided and may include an ultraviolet UV source providing a predetermined wavelength of radiation to provide a detrimental effect to virus and/or bacteria, an exposure chamber for exposing a predetermined volume of blood to radiation, a conduit between the UV source and the exposure chamber, a pump for pumping blood between a first location and a second location and a shutter assembly provided between the UV source and the exposure chamber providing time-metered irradiation of the blood in the chamber.
    Type: Application
    Filed: May 12, 2009
    Publication date: September 10, 2009
    Applicant: ENERGEX SYSTEMS, INC.
    Inventor: Thomas R. Petrie
  • Patent number: 7569026
    Abstract: A bag connection comprises a first bag, a tube having a blood-drawing needle at the front end, a plurality of second bags, tubes for connecting the first and second bags, and tubes and branch connectors for connecting the second bags to each other. On the other hand, a filter unit includes a filter, and a tube connected at opposite ends thereof to the inlet and outlet of the filter. The tubes of the bag concatenation and the tube of the filter unit have respective markers attached thereto. With these markers used as marks, both tubes are aseptically connected by a tube aseptic connection device, thereby incorporating the filter unit into an intermediate portion of a tube of the bag concatenation.
    Type: Grant
    Filed: September 29, 2004
    Date of Patent: August 4, 2009
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Hiroyuki Sugawara
  • Patent number: 7566315
    Abstract: A blood component collection apparatus comprises a blood component collecting circuit which includes an anticoagulant line for feeding an anticoagulant and a line for collecting an initial flow of collected blood. In the blood component collection apparatus, air is intermediately present between the anticoagulant and the blood in the passage of a blood collection needle side line, after a priming operation is performed in which anticoagulant is supplied from the anticoagulant line toward the side of a centrifugal separator in the blood collection needle side line through a branch connector and after an initial flow collecting operation is performed in which the initial flow of blood is collected.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: July 28, 2009
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Makoto Hirabuki
  • Publication number: 20090187132
    Abstract: A liquid collection bag is used as a part of an extracorporeal circuit and is connected via a tube to a storage container containing a priming solution. The collection container collects the priming solution from the storage container by a pressure differential between the pressure inside the collection container and the pressure inside the storage container. The liquid collection container is a flexible bag body having a partition part dividing the inside of the bag body into a first space and a second space. In addition, a communication part communicates the first space with the second space.
    Type: Application
    Filed: January 16, 2009
    Publication date: July 23, 2009
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Norikazu ISHIDA, Hidetaka Nakayama
  • Patent number: 7559911
    Abstract: A blood chamber for extracorporeal blood circuits comprises a container body (2) made in a single piece by blowing of a plastic material, and has a plurality of connection ports (3, 4) for fluid communication with outside; each connection port (3, 4) comprises a tubular mouth (6) having a truncoconical internal surface (61) which is coupled in a fluid-proof coupling to a tubular first part (101) of an insert (10), made by injection molding of a plastic material. The insert (10) has a truncoconical and smooth internal surface (102) which is coupled by gluing with a solvent to an end zone of a fluid transport tube (7, 8). The coupling between the blood chamber and the fluid transport tubes is very strong and reliable. The blood chamber is part of an extracorporeal blood circuit which is operatively associated to a dialysis machine.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: July 14, 2009
    Assignee: Gambro Lundia AB
    Inventor: Carlo Giannella
  • Publication number: 20090131847
    Abstract: A system for medically treating/vaccinating an individual comprising a first syringe, containing an anticoagulant material therein, for drawing a sample of blood from the individual. A centrifuge means for centrifuging the sample of blood contained within the first syringe to obtain a buffy coat. A second syringe comprising a second plunger and at least one microtubule member containing one of a treatment agent and a vaccine antigen. At least one open end formed within the at least one microtubule member for drawing a portion of the buffy coat therein and exposing the buffy coat to one of the treatment agent and vaccine antigen. A second needle capable of being attached onto the second syringe for introducing the exposed sample into the individual to effect treatment/vaccination thereof. This system is capable of allowing a plurality of treatment agents and/or vaccine antigens to be simultaneously applied to an individual.
    Type: Application
    Filed: October 24, 2008
    Publication date: May 21, 2009
    Inventor: David R. Nalin
  • Publication number: 20090124954
    Abstract: A system and method for autologous normovolemic hemodilution (ANH) are disclosed. The system can include a vacuum canister, which is sized to accept donor bags of a predetermined capacity. The vacuum canister is connected to a vacuum source which applies a suction to the donor bag within the canister. The system can include a canister having a self-generated vacuum, which includes compressible sidewalls that are spring-loaded to provide negative pressure needed to collect blood from a patient without the use of a gravity-induced siphon gradient. Also disclosed are ANH systems and kits that rely on a gravity-induced siphon gradient for blood collection.
    Type: Application
    Filed: January 16, 2009
    Publication date: May 14, 2009
    Applicant: UNIVERSITY HOSPITALS OF CLEVELAND
    Inventor: James R. Trickett
  • Publication number: 20090062716
    Abstract: An example of the closed-type blood reservoir of the invention is furnished with an outer shell in which a space is formed within its interior, a flexible septum that is interposed between a blood storage chamber shell and a volume adjustment chamber shell and that divides the space into a blood storage chamber for storing blood and a volume adjustment chamber for storing volume adjustment liquid, a blood inlet port, a blood outlet port, and a blood storage chamber air discharge port that are provided in the blood storage chamber shell such that they are in communication with the blood storage chamber, and a volume adjustment liquid port that is provided in the volume adjustment chamber shell such that it is in communication with the volume adjustment chamber, for injecting and ejecting the volume adjustment liquid into and away from the volume adjustment chamber, wherein the blood inlet port and the blood outlet port each are provided tangentially to the inner surface of the blood storage chamber shell such
    Type: Application
    Filed: October 3, 2006
    Publication date: March 5, 2009
    Applicant: JMS Co., Ltd.
    Inventors: Hiroyuki Maeda, Shigeki Kawarabata
  • Patent number: 7488297
    Abstract: Blood collecting devices for collecting blood from a patient using a single needle insertion are disclosed. Each blood collecting device typically includes a housing which is removably attached to a test tube or blood reservoir. A blood flow tube is disposed in fluid communication with the housing for distributing blood from a patient into the test tube or blood reservoir. The blood is distributed through a membrane cavity having a liquid-impervious and air-permeable membrane. At least one air opening is provided in the housing at the membrane cavity. Accordingly, air in the test tube or blood reservoir is displaced by the incoming blood through the membrane cavity and membrane and out the air opening or openings. Vacuum pressure in the test tube or blood reservoir is dispelled by the flow of air through the air opening or openings, membrane cavity and membrane and into the test tube or blood reservoir, respectively.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: February 10, 2009
    Inventor: Patrice Flaherty
  • Publication number: 20090036816
    Abstract: A blood tube system for extracorporeal uses, such as dialysis devices, wherein an arterial expansion chamber including a lower region for receiving blood, in which a blood inlet channel terminates, and from which a blood outlet channel extends, and an upper region for receiving air, where a venting channel provided with a venting valve extends from the upper region. The blood tube system includes a central region of the expansion chamber which has considerably reduced cross-sectional dimensions, the blood level being adjustable by means of the venting valve in such a manner that blood/air contact takes place in the central region. The amounts of heparin and EPO needed for a dialysis treatment can thereby be reduced.
    Type: Application
    Filed: July 31, 2008
    Publication date: February 5, 2009
    Inventors: Franz Ferdinand Becker, Thomas Ryzlewicz, Reinhold H. Herbst
  • Patent number: 7485260
    Abstract: Venous reservoirs are interposed between the patient and the arterial pump and serve to remove air bubbles and provide compliance that accommodates variations in the volume of blood circulating in the extracorporeal circuit during cardiopulmonary bypass (CPB). The invention is a reservoir that incorporates automated means to remove air bubbles from the venous line prior to the blood entering the arterial blood pump. In another form, the reservoir includes means that handles foam prior to the blood entering the blood pump. In yet another form, the invention is means that improve air removal in a soft shell venous reservoir. These features are applicable to CPB circuits using gravity drainage or vacuum assisted venous drainage.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: February 3, 2009
    Inventor: Yehuda Tamari
  • Patent number: 7479130
    Abstract: A system and method for autologous normovolemic hemodilution (ANH) are disclosed. The system can include a vacuum canister, which is sized to accept donor bags of a predetermined capacity. The vacuum canister is connected to a vacuum source which applies a suction to the donor bag within the canister. The system can include a canister having a self-generated vacuum, which includes compressible sidewalls that are spring-loaded to provide negative pressure needed to collect blood from a patient without the use of a gravity-induced siphon gradient. Also disclosed are ANH systems and kits that rely on a gravity-induced siphon gradient for blood collection.
    Type: Grant
    Filed: December 23, 2005
    Date of Patent: January 20, 2009
    Assignee: University Hospitals of Cleveland Case Western Reserve University
    Inventor: James R. Trickett
  • Patent number: 7473395
    Abstract: A system for rapid induction of indication of hypothermia especially of the heart and brain during cardiac arrest and normal circulation. The device recirculates blood through an extracorporeal circuit using a single venous access. The blood can be cooled and/or treated before reentry to the vascular system. The device maximizes the cooling rate by optimizing the blood withdrawal rate. Cooling of the brain is achieved by flow of cooled blood from the thorax to the head. During cardiac arrest, the blood flow is generated by cardiopulmonary resuscitation.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: January 6, 2009
    Inventors: Menekhem M. Zviman, Henry R. Halperin
  • Patent number: 7473238
    Abstract: A disposable fluid circuit kit for extracorporeal blood treatment systems that supply replacement fluid to a patient is described. The circuit has a blood portion that carries blood and subjects it to some treatment, such as dialysis or hemofiltration. A portion carries filtrate or dialysate. A replacement fluid portion that carries fluid used to compensate for fluid loss is connectable to a supply of replacement fluid. a sterilizing filter in the replacement fluid portion sterilizes the replacement fluid before introduction into the patient acting as a guard against touch contamination of the connected replacement fluid container. Preferably, the filter has a pore size effective to eliminate pyrogens.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: January 6, 2009
    Assignee: NxStage Medical, Inc.
    Inventors: James Brugger, Jeffrey H. Burbank, Dennis Treu
  • Publication number: 20090005719
    Abstract: The invention relates to the field of blood treatment machines with a blood treatment module to hold components of an extracorporeal blood circulation. To simplify access to a securing means (21) that is attached to a vertical infusion rod (20) attached to the blood treatment machine (1) for securing objects, in particular containers such as bags (11) containing medicinal fluids, a blood treatment machine (1) with a housing (2) and a blood treatment module (3) is proposed, whereby vertical and horizontal directions are defined by the orientation of the housing during the use of the blood treatment machine, having a rod-shaped means (20) attached to the housing, whereby the rod-shaped means (20) have at least one first section (22) and a second section (23), whereby the axial extent in the second section (23) runs in a different direction than in the first section (22). In another embodiment, the rod-shaped (20) have a cropped course.
    Type: Application
    Filed: September 10, 2005
    Publication date: January 1, 2009
    Inventor: Winfried Brehm
  • Publication number: 20080312576
    Abstract: A plunger-less syringe, method of manufacture and system of use is disclosed wherein the syringe includes a barrel that has an interior receptacle for receiving a quantity of blood. The syringe has at least one filter that controls fluid flow within the syringe. The syringe may be fabricated from a material that prevents diffusion of the gas from the blood. Different syringes may comprise different fluid flow characteristics. In addition, the components of the syringe may include indicia so a syringe having particular characteristics can be selected for patients with different blood pressure.
    Type: Application
    Filed: June 16, 2008
    Publication date: December 18, 2008
    Inventors: Robert J. McKinnon, James Dale Bickley