Abstract: A medical fluid administration set is disclosed which may be used for the passive reconstitution and delivery of a drug or other beneficial agent with liquid flowing through the administration set. A receptacle mounted in the administration set is adapted for receiving a cartridge containing the beneficial agent. Also disclosed is an adapter for connecting the cartridge and the receptacle and an air flask within the administration set.

Abstract: An injection site for the infusion of a medicament into a flow path for a parenteral fluid and, more particularly, an injection site which is essentially self-priming and air-occluding and which is of extremely simple construction and easily assembled. Furthermore, the invention is also directed to an injection site of the type described herein which is especially adapted for use as an injection port of a Y-connector utilized for an intravenous administration set. The device incorporates a self-sealing puncturable member of resilient material, such as rubber, which member is of a substantially spheroid configuration, the tubular segment so as to be in close proximity to the and which is swage-molded into a receiving housing in the tubular segment so as to be in close proximity to the inlet tubing for the flow path of the parenteral fluid.

Abstract: A flow control device in which a plurality of flow channels converge in a two-part housing containing a free-floating and pre-biased flow control diaphragm and an injection site. The free-floating diaphragm is at the entry position of an intermediate channel which extends to an output channel of the injection site. The control diaphragm is pre-biased by a prong which extends from a base portion of the two-part housing.

Abstract: A conical shield for attachment to a conventional admixture site which effectively and economically provides: 1) positive needle-thick protection for an individual administering medication; 2) secure locking of the device to the admixture site; 3) security from accidental disconnection of the intravenous solution and; 4) a method whereby the caps of hypodermic needles may be safely removed, stored during injection of medication or withdrawal of body fluids and returned to cover the needle following use.

Abstract: A needle shield that can be clamped about the line of a flow path used to administer IV fluids to a patient immediately beneath an insertion port to protect a health care worker from receiving acccidental needle wounds.

Abstract: A surgically implantable infusion port includes a housing portion, a penetrable elastomeric septum portion which cooperates with the housing portion for defining an interior cavity and a catheter element which extends outwardly from the interior cavity for dispensing medication therefrom at a predetermined location in the body of a patient. The elastomeric septum portion is penetrable by a hypodermic needle for dispensing medication in the interior cavity, and it is laterally compressed to enhance the ability of the septum portion to reseal itself after being repeatedly penetrated. A septum assembly including a similar laterally compressed septum element can also be utilized as a penetrable barrier between various liquids and gases.

Abstract: An assembly for connection to at least one medicant supply tube, includes (a) a septum assembly including a distal end cap having opposite first and second ends, an outer peripheral wall extending between the first and second ends and a bore extending therethrough from the first end to the second end; a septum cap including a puncture sealing section positioned over the first end and a securing section integrally formed with the puncture sealing section and positioned in fluid sealing contact with the peripheral wall adjacent the first end so as to secure the septum cap to the distal end cap; and a proximal connector connected with the distal end cap in covering relation to the septum cap, the proximal connector including a bore extending therethrough and a connection at one end thereof; and (b) an external adapter fitting having a septum piercing tube for piercing the puncture sealing section when the external adapter fitting is connected with the proximal connector, and a luer lock connection cooperating wi

Abstract: Implantable infusion apparatus includes a housing with an inlet passage extending into the housing at a pronounced promontory on the housing wall. The passage has an outer end at the top of the promontory and an inner end defined by a needle stop positioned inside the housing. Self-sealing septa mounted in the passage at selected spacings from the needle stop divide the passage into a plurality of aligned inlet ports each of which has its own fluid outlet. One of the outlets leads to a pumpable infusate reservoir having an outlet conduit connected to a catheter that extends outside the housing; another leads directly to the outlet conduit so that while a first fluid is being pumped from the reservoir to the catheter, a second fluid can be introduced into the other inlet port for mixing with the first fluid flowing to the catheter. Several different infusate flow configurations are also disclosed.

Abstract: An injection site platform for use in adding a needle injected medication to a parenteral fluid being provided to a patient includes a base and an outlet port of a size and shape to receive a needle piercable resealable diaphragm. There is a conical wall which connects the outlet with the base, with the smaller diameter portion of the conical wall being integral with the outlet and the larger diameter portion terminating at the base. The conical wall provides a needle guide to the diaphragm positioned in the outlet and access for the application of an antiseptic wipe to the diaphragm. A portion of the platform has an opening for a tube carrying parenteral fluid, whereby the tube may be manually constricted by pressing it against the platform adjacent the opening.

Abstract: A medical intravenous line coupling device can be secured to standard "y" shaped junction tube. The device can comprise a single member which fits with the junction tube and has passages shaped to receive and secure with the junction arm. A "b" shaped slot can be provided in the member for that purpose. The container can have a menas for receiving a liquid for injection into the intravenous system, such as a receptacle, and a means for allowing liquid flow from the receiver into the junction tube, such as a needle. The device may include a second member which has a passage to interact with the junction arm. One member can fit about the other and be rotatably mounted hereto. The junction arm can be received by the two members when they are in a first position relative to one another, and can be secured when the members are moved relative to each other. With the two member assembly, the receiver, such as the receptacle, and the liquid flow means, such as the needle, can be mounted to the first or second member.

Abstract: A cartridge for introducing a beneficial agent into a medical fluid conduit is disclosed. The cartridge includes a pierceable stopper having a hollow, open ended protrusion extending into the cartridge chamber and having the beneficial agent retained therein by a liquid pervious barrier. The hollow, open ended protrusion creates a directed flow path within the cartridge.

Abstract: A Y-joint eliminates air space between an injection member and an injection uct by inducing flow from the intake duct towards the injection membrane. The induced flow may be generated by a deflection duct or a bypass duct. In either case, fluid infusion solution is induced to flow in a direction opposite the normal flow of the discharge duct.

Abstract: An injection site device having a shield extending outwardly from the tubular body thereof between the injection port and the outlet port in order to protect the fingers of the user when a needle is being introduced into the injection port of the injection site device.

Abstract: A self-priming injection site having a stopper that resists dislocation or removal from the injection site. The stopper is positioned within the plastic housing between a top with an open center and an intermediate ledge having an upturned lip. The stopper includes an annular groove that receives the upturned lip of the intermediate ledge, to assist in holding the stopper in compression within the housing. An arm portion allows the intravenous fluid to enter the injection site on a path approximately parallel to and immediately adjacent to the ledge and the bottom of the stopper. A check valve may be positioned within the arm portion.

Abstract: Combination intravenous infusion/blood sampling and medication injection apparatus is provided whereby a patient may be administered an intravenous infusion fluid and be subjected to blood sampling or medication injector procedures without the need to make or break any fluid connection in a sealed closed system in order to prevent possible contamination from entering the apparatus and causing injury to the patient. In combination, a three-way valve and a diaphragm sealed blood sampling apparatus is connected to intravenous infusion and catheter tubing and a flushing syringe having sterilized connections is provided. The patient need only be connected to the catheter needle once and by manipulation of the three-way valve in conjucntion with the flushing syringe, the tubing may be purged of the intravenous infusion fluid.

Abstract: A method of utilizing an apparatus of the type comprising a vial container hazardous material in the vial container in a condition requiring a diluent to be mixed therewith to form the liquid solution, and an assemblage carried by the vial container for providing (1) a sealed medicament chamber within the vial container within which the hazardous material is disposed, (2) a filter vented control chamber and (3) a sealed variable volume control chamber between the vented control chamber and the medicament chamber. The method is such as to enable an open end of a syringe needle of a diluent syringe having a syringe chamber containing diluent in communication therewith to be moved into and withdrawn successively from the chambers so as to mix the diluent with the hazardous material. The method also contemplates procedures for separately refilling a dosage syringe and for relieving any residual pressure in the vial chamber with the use of an empty syringe prior to initial or final refilling of a dosage syringe.

Abstract: A protective device for enclosing the scarf of a cannula carried by a boss while permitting access to the said scarf by a port of a Y-site which is located into proximity to an adjoining length of flexible tubing forming part of an intravenous administration set. The protective device has a cylindrical sheath portion surrounding the cannula, the ends of the cylindrical portion having at least one cutout which snugly receives the flexible tubing.

Abstract: An apparatus is disclosed for introducing a liquid within a material. The apparatus comprises a body member having an internal cavity for receiving a battery. An end member is secured to the body member for supporting a needle guide extending through the end member for slidably receiving a needle. A reciprocal coupling means interconnects the motor and the needle for reciprocating the needle relative to the end member upon rotation of the motor. A reservoir is in fluid communication with the needle for retaining the liquid therein and for enabling the liquid to flow along the needle. The reciprocating needle creates a plurality of perforations in the material enabling the liquid to flow along the needle to enter the perforations. The apparatus is suitable for introducing a liquid pigment into a skin tissue such as introducing a permanent eyeliner into an eyelid.

Abstract: A method and apparatus for increasing the accuracy of administration of intravenous medicinal fluids including an elongated matrix device attachable to a plurality of intravenous tubes, so that each tube is disposed in spatial and visual alignment with an indicia device on which the type of fluid flowing in the tube and the identification of the body port to which the fluid is flowing is recorded, as well as visual means, such as staggered positioning, is used to visually connect the tubes coming into the matrix with the corresponding effluent tube to a particular body portal, and including the use of color coding as an enhancement to the basic arrangement.

Abstract: In order to withdraw pharmaceutical products from sterile vials by means of a syringe, apparatus is used on one end of which a syringe possibly containing a liquid solvent is mounted and at the other end of which a seat is provided for housing the mouth of a vial. The syringe needle can puncture the rubber or similar stopper by which the vial is sealed, while the needle itself remains enclosed and protected by said apparatus. The invention relates to a device which, when the vial has been removed, can itself be housed in said apparatus seat to enable the needle to puncture a rubber stopper provided on the device, which is connected to one end of a cannula having for example mounted on its other end a needle for transfusion purposes. In this manner, the liquid can be discharged from the syringe while the needle remains enclosed and protected by the said apparatus.

Abstract: A subcutaneous access site to aid in the delivery of chemotherapeutic or analgesic drugs to the blood stream or to any body cavity. The device embodies a specially supported septum which exhibits exceptional resealing characteristics. In this regard, the device includes a rigid inner ring adapted to create uniform circumferential compression on the septum member to enhance site resealing even when standard twelve degree beveled hypodermic syringe needles are used. Additionally, the device is uniquely configured to give immediate feedback to the caregiver if the needle misses the target, thereby minimizing accidental subcutaneous injections.

Abstract: Improvements and accessories for a septum closed T-shaped blood access device adapted for implantation into a patient. The implantable device has a stem portion extending above the skin of the patient and defining a septum closed opening into the device. The improvements include an improved septum having a groove in the side thereof encircling the septum and an elastomeric ring carried within the side groove, an improved needle assembly which provides access to the circulatory system through the septum, and a flexible cap for sealing the stem of the implantable device from the outside atmosphere which may be fitted in place or removed without the necessity of specialized tools.

Abstract: A container for intravenous fluid has a triangular cross-section to permit improved utilization of space during packaging of several containers in boxes or cartons, and a first opening sealed by a membrane seal which can be pierced with the spike of a conventional intravenous set. A second opening of the container is surrounded with a neck portion forming a joint to which an intermediate member is pivotably mounted. The intermediate member includes a hollow cylindrical portion having two circumferential ribs which are adapted to hold the neck of a standard small vial containing solid antibiotics and the like. The intermediate member also includes an internally mounted hollow spike so that the seal of the antibiotic vial is penetrated by the spike when the vial is mounted to the intermediate member. The duct of the spike of the intermediate member is not aligned with the second opening of the container until the intermediate member is rotated or pivoted into an extreme position.

Abstract: A disposable injection transmitter for use between injecting needles and a primary injection site. A body having a passage through it. A hollow auxiliary needle joined to the body in communication with one end of the passage and adapted to penetrate through and reside in the primary injection site. An elastomeric wall joined to the body and covering the other end of the passage and adapted to receive a series of injecting needles through it to inject fluids into or beyond the passage.

Abstract: An improved endotracheal tube apparatus (10) comprising an endotracheal tube unit (11) and an injection site adjunct unit (12) wherein the tube unit (11) is provided with a primary endotracheal tube passageway (14) in communication with a respirator (100), and a lumen side port (16) formed in the wall (15) of the primary tube passageway, wherein the lumen side port (16) is in open fluid communication with the injection site adjunct unit (12) and the interior of the passageway (14) whereby liquid medicants may be introduced into the passageway.

Abstract: An improved multiple re-entry implantable septum is disclosed. The septum comprises a casing and a resilient member positioned within the casing. The resilient member has a perforation therein which is compressed closed. An outer side of the casing presents a relatively large surface configured to channel the end of a slender, elongate component such as a needle to a predetermined location at a relatively small bore in the outer side of the casing. The small bore in the casing is located adjacent the perforation in the resilient member. An assembly of a first needle and a cannula positioned over the needle is inserted into the skin so that the end of the needle contacts the relatively large surface of the casing and is channeled to the small bore therein. The bore is dimensioned to prevent passage of the first needle through the casing. The first needle is withdrawn from the casing and skin leaving the plastic cannula in place adjacent the small bore.

Abstract: A tube set intended for extracorporeal treatment of blood and similar perishable liquids, e.g. by dialysis, includes a spacer adapted to rigidly connect an inlet end of a pump segment for a tube pump to an outlet end of the pump segment. The spacer is adapted to transfer liquid to and from the pump segment. Ports may be provided in the spacer for the purpose of withdrawing liquid samples from the spacer or supplying reagents or priming fluids to the liquid flowing through the spacer. A stay formed integrally with the spacer supports the spacer against the tube pump.

Abstract: A coaxial double lumen tube for use in hemoaccess which comprises an outer tube positioned over an inner tube, both tubes having an internal and external diameter and a wall thickness, the outer tube having an internal diameter which is at least 1 mm larger than the external diameter of the inner tube creating a space between the outer tube and the inner tube and a self-sealing, nonbiodegradeable, biocompatible polymer adhesive which evenly fills the space between the outer tube and the inner tube.

Abstract: A flow device including a plurality of flow channels which converge in a common housing containing a pre-biased flow control diaphragm at the position of convergence of at least two channels. The control diaphragm is pre-biased by a set of prongs which extend from an integral portion of the common housing.

Abstract: A container mixing system wherein a medicament is placed in a container mounted externally of a container with a diluent. Mixing of the medicament in one container with the diluent in the other is accomplished by attaching an additive assembly with a piercing element to an additive port of the diluent container to pierce a diaphragm in the additive port and a diaphragm or stopper in the additive container. In one embodiment, the additive assembly includes a bellows portion which will permit movement of the piercing element through the additive assembly stopper and the port diaphragm while maintaining a sterile medicament in a glass vial.

Abstract: An injector for infusion or transfusion systems utilizes a housing having a duct extending longitudinally therethrough. The inner surface of a penetrable membrane covers an end of the duct, with the edge of the surface abutting an annular shoulder of the housing. A ring is disposed in an annular indentation on the periphery of the outer surface of the membrane, with the outer edge of the inner surface of the ring abutting a second annular shoulder of the housing. The outer surface of the ring and the central portion of the outer surface of the membrane are flush.

Abstract: Solid, soft, penetrable, non-coring material for filling a side-arm injection port of an intravenous tube. The material occludes the injection port or other site where air or administered medications may be trapped in the tubing. The material fills the area that lies out of the main stream of the intravenous infusate while allowing medication injection through the non-coring material. The material also decreases or practically eliminates any weeping from the numerous injections into a port, lessening the chance for sepsis.

Abstract: The invention relates to a dosing device for fluids used in infusion or transfusion systems comprising a flexible fluid line transversing a housing to compress the fluid line. The device comprises a housing and an elastomeric tubular element having leading and trailing sections which traverses said housing to interconnect respective ends of said fluid line. The tubular element comprises a thicker portion between the leading and trailing sections whereby the thicker portion protects against longitudinal displacement of the housing. A pressing element engages the tubular element outside the region of the thicker portion.

Abstract: A device for use in equalizing the pressure inside a vial during the addition or removal of fluid comprising a one piece sterilizable device for use in equalizing the pressure inside a vial during the addition or removal of fluid which comprises a cannula having a sharpened beveled lower end for puncturing the septum of a vial, a blunt upper end covered with a septum that can be punctured by the needle of a hypodermic syringe, and an enlarged annular portion below the blunt upper end limiting entry of the device into the vial, said enlarged annular portion having an air channel leading from the inside of the cannula through the enlarged annular portion to the outside of the cannula said air channel being provided at its outer end with means for one-way air flow.

Abstract: Valved adaptors are disclosed permitting the introduction of a drug-containing vial in the delivery tube of an I.V. administration set. The adaptors have a three position operation characterized by a bypass mode, a dilution mode, and a delivery mode, the adaptors being manually changed from mode to mode. The disclosed adaptors include gravity operated valves, reciprocating spool valves, and rotating spool valves, each including a spike to penetrate the stopper of a vial and a vent to permit air to escape the vial as liquid is introduced to dilute the vial contents.

Abstract: In a fluid administration set of otherwise conventional design, an in-line chamber is provided having an inlet and outlet port communicating with the chamber and defining part of the path of flow through the set. A sealing piston is slidably movable by fluid pressure within the chamber and capable of occupying first positions in which the sealing piston isolates fluid in the chamber adjacent the inlet port from fluid in the chamber adjacent the outlet port. The sealing piston also can occupy at least one second position in which unlimited fluid flow is permitted between the inlet port and outlet port. A third port is provided for intermittently inserting a critical fluid into the chamber on the side of the sealing piston facing the outlet port.

Abstract: Infusion apparatus includes a housing with an infusate chamber in the housing and means for conducting infusate from the chamber through a restrictive outlet passage to an additional small chamber having an entrance port closed by a self-sealing penetrable septum. An exit tube from the small chamber leads directly to a cannula at the infusion site so that liquid can be injected into the small chamber through its septum and delivered directly to the infusion site without backflowing into the infusate chamber.

Abstract: A tubing injection site guard comprising a compressible, penetrable sleeve for surrounding a continuous tube and a rigid casing enclosing the sleeve. The casing comprises two opposing longitudinal sections longitudinally hinged, with a needle access port in one section to allow insertion of a needle through the sleeve and into the tube. The sections are capable of being locked together to radially compress the sleeve over its entire length and thereby seal needle holes. An adjustable locking means is provided to lock the sections together and to allow adjustment of the radial compression. The site guard also protects the operator from injury while inserting the needle by enclosing the entire injection site except at the needle access port.

Abstract: A tamper indicating device (24) is connected to the inlet (14) of an injection site (10) which inlet (14) includes a pierceable, self-sealing member (16). The tamper indicating device (24) comprises a cap (26, 28) which covers the inlet (14) rendering the pierceable, self-sealing member (16) inaccessible. A first portion (26) of the cap is connected to the inlet (14) and a second portion (28) of the cap is separated from the first portion (26) by a frangible section (30). A handle (32) extends from the second portion (28) and is operable when actuated to break the second portion (28) away from the first portion (26) at the frangible section (30), rendering the pierceable, self-sealing member (16) accessible. The first portion (26) remains connected to the inlet (14) to indicate that tampering has occurred.

Abstract: Injection site device comprising an elastomeric plug closing a fluid entry port and held in a compression fit by means of an open overcap bonded to the outer surfaces of the entry port.

Abstract: A check valve housing is rigidly attached to the first inlet of an injection site having a body portion, a first inlet, a second inlet and an outlet. The check valve housing encloses a duckbill valve member and has an interior wall which securely and frictionally engages a portion of the external surface of the duckbill valve member.