Abstract: An injector for inserting an intraocular lens into the capsular bag of an eye has an injector body; a plunger for displacing the lens out of the injector in an insertion direction, with the lens having an optic body with an optical axis and a rear and a front haptic; a rear mechanism for displacing an optic body distant longitudinal end of the rear haptic onto the optic body via a displacement of the plunger; a front mechanism for displacing an optic body distant longitudinal end of the front haptic along a front trajectory having a front component parallel to the optical axis; and a handle operable from outside of the injector and which has a first catch coupled to the plunger to carry along the plunger in the insertion direction via a longitudinal displacement of the handle and has a second catch to carry along the front displacement mechanism.

Abstract: A specimen retrieval system is disclosed. The specimen retrieval system includes a first hollow tube including one or more cutting elements on a first end of the first hollow tube, a first gear on a second end of the first hollow tube, a second hollow tube movable relative to the first hollow tube a second gear on a first end of the second hollow tube, a rack coupled to the first gear and the second gear, and a first actuator coupled to the rack. A second end of the second hollow tube may include cutting elements. The specimen retrieval system also includes a rack coupled to the first gear on the first hollow tube and the second gear on the second hollow tube. The specimen retrieval system may also include a geared tenaculum disposed inside the first hollow tube, and a second actuator coupled to the geared tenaculum.

Abstract: An insertion system for inserting an IOL int a patient's eye is provided. The insertion system includes a pusher and an introducer sheath with a back housing and a front housing. The front housing includes a longitudinally extending IOL rolling member with a proximal section, an intermediate section, a distal section and a longitudinally extending lumen defined by an upper face and a lower face. The lower face has opposing inner peripheral edges. The radius of curvature of the upper face and the lower face decreases from the proximal section to the distal section and the distance between the opposing inner peripheral edges decreases from the proximal section to the distal section.

Abstract: An electromagnetic valve has a magnetic coil and a movable element coupled to a valve element. The magnetic coil, when excited, conveys the movable element in one direction to move the valve element from its initial position into its active position. A control circuit for the electromagnetic valve has a current source for optionally supplying current to the magnetic coil and a measuring device for measuring a voltage level of the magnetic coil and/or a current level through the magnetic coil. A monitoring unit which is connected to the measuring device establishes a switching state of the electromagnetic valve corresponding to the position of its valve element based on the intended current supply state of the current source and the current and/or voltage characteristic measured by the measuring device and, if appropriate, determines a fault state of the current supply and/or the electromagnetic valve.

Abstract: An intraocular lens insertion device which dramatically reduces the possibility that a plunger damages an intraocular lens, and which can safely and surely insert an intraocular lens into an eye is provided. An intraocular lens insertion unit comprises a lens disposing part for disposing an intraocular lens, a plunger for pushing out the intraocular lens disposed at the lens disposing part, a transition part for deforming the intraocular lens pushed out by the plunger, and a nozzle for ejecting the deformed intraocular lens. The plunger has a lens contact part for contacting the outer edge of the intraocular lens, and a protrusive part for pushing the lens contact part downward the intraocular lens by the deformation of the intraocular lens, both lens contact part and protrusive part are provided at the leading end of the plunger.

Abstract: A device for the preparation of a Descemet's membrane-endothelium graft includes a bowl with an inner bottom and a sidewall surrounding the bottom, particularly the bowl being configured to receive a fluid and a Descemet's membrane-endothelium graft or a donor cornea graft comprising a Descemet's membrane-endothelium graft floating in the fluid, a preparation area positioned in a first part of the inner bottom of the bowl, particularly for receiving and preparing the graft prior to transport, a transfer area positioned in a second part of the inner bottom between the preparation area and an outlet opening in the sidewall, particularly the opening being entirely positioned below the upper rim of the sidewall.

Abstract: Systems, methods, and apparatuses for storing and/or shipping an intraocular lens (IOL) cartridge are provided. A system comprises the IOL cartridge. The IOL cartridge comprises a nozzle and a compartment comprising an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge further comprises a dial disposed adjacent to the compartment, wherein an inner surface of the dial is exposed to the compartment. The dial is configured to fold the IOL upon rotation of the dial. The IOL cartridge further comprises a plunger case in fluid communication with the compartment, wherein a plunger is movably disposed within the plunger case. The IOL cartridge is configured to removably attach to a handpiece.

Abstract: An apparatus for delivering an implant to an eye using hydraulic fluid flow or pressure. An implant may be stored, advanced, and delivered to an eye using hydraulic fluid stored in a sterile container through a hollow advancement plunger. The plunger may rigidly advance the implant to a sealed position in a first phase, and then the implant may be advanced into the eye via hydraulic pressure or fluid flow in a second phase.

Abstract: A device for manipulating an implant includes a handle coupled to a guide extending from the handle to a distal end. The device includes an engagement mechanism disposed at the distal end of the guide and configured to engage an implant. The device includes a first actuator disposed on the handle and coupled to the engagement mechanism. The first actuator causes the engagement mechanism to engage the implant. The device includes an air chamber disposed in an interior chamber of the handle and configured to hold air. The device includes a lumen coupled to the air chamber and extending along the guide to the distal end. The lumen includes an air channel extending through the lumen. The device includes a second actuator disposed on the handle. The second actuator causes the air chamber to deliver the air, via the air channel, to the distal end.

Abstract: A portable device for attaching a contact lens to an eye includes a first clamp including a first grip portion having a first grip hole and a first arm including two branches extending from the first grip portion, each branch extending obliquely and being bent, and a second clamp having a shape identical to the shape of the first clamp, the second clamp including a second grip portion having a second grip hole and a second arm, wherein the first arm and the second arm are coupled to each other so as to intersect each other about a pivot point, and a first eye opening means and a second eye opening means are installed at tip ends of the first arm and the second arm, respectively, each eye opening means being configured to be brought into tight contact with a corresponding eyelid.

Abstract: Systems, methods, and apparatuses for storing and/or shipping an intraocular lens (IOL) cartridge are provided. A system comprises a packaging comprising a passage. The IOL cartridge is removably disposed within the passage. The IOL cartridge comprises a nozzle and a compartment configured to receive an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge further comprises a dial configured to rotate upon withdrawal of the IOL cartridge from the passage, wherein an inner surface of the dial is exposed to the compartment. The dial is configured to fold the IOL and release the IOL cartridge from the packaging upon rotation of the dial.

Abstract: A surgical device for implanting an artificial cornea into an eye can comprise an installation tool comprising an implantation end for receiving a back portion of an artificial cornea. The installation tool can further comprise a drive nut positioned above the implantation end. The surgical device can further comprise a thumbscrew that is received within the drive nut. The thumbscrew can be rotatable relative to the drive nut to adjust a position of the thumbscrew. During an implantation procedure, the implantation end with the back portion of the artificial cornea positioned thereon can be inserted into the eye, and the thumbscrew can be rotated relative to the drive nut to interact against a front portion of the artificial cornea to lock the artificial cornea in place.

Abstract: Various systems and techniques for inserting an intraocular lens are disclosed. In particular implementations, a system and a technique for inserting an intraocular lens may include the ability to move, in response to a force being applied in a first direction along a longitudinal axis, a first plunger tip along the longitudinal axis and into a delivery cartridge to fold an intraocular lens and move in a second direction along the longitudinal axis in response to the applied force being reduced. The system and the technique may also include the ability to engage a second plunger tip and move, in response to a force being applied in the first direction along the longitudinal axis, the second plunger tip along the longitudinal axis and into the delivery cartridge to insert the intraocular lens.

Abstract: A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation.

Abstract: The invention relates to an injector assembly having: a folding chamber which is designed to receive an intraocular lens which has an optical body and two haptic elements; a holder; a folding wedge which is attached to the holder and is designed to be introduced into the folding chamber via a folding chamber opening, thereby folding the intraocular lens; and a first slider and a second slider which are each designed to push one of the two haptic elements onto the optical body by means of a displacement of the respective slider from a starting position to an end position, the holder being designed to drive the first slider and/or the second slider from the starting position to the end position by means of a movement of the holder towards the folding chamber.

Abstract: A method for cataract surgery includes incising a continuous curvilinear capsulorrhexis (CCC) in an anterior capsule of a lens of an eye, inserting an endoillumination probe into the lens through the CCC, further inserting the endoillumination probe to a location below an equator of the lens and below a nucleus of the lens, tilting the endoillumination probe to laterally aim light emitted from the endoillumination probe behind the nucleus, and chopping the nucleus with a chopper needle of the endoillumination probe. The chopping further includes chopping the nucleus with a phaco tip.

Abstract: A tissue resecting instrument includes an end effector assembly having a proximal hub housing, a retainer cap extending proximally therefrom, an elongated outer shaft extending distally from the proximal hub housing, an inner cutting shaft rotatably disposed within the elongated outer shaft, and an inner core drive assembly that includes a proximal driver and a distal driver. The distal driver is coupled to the inner cutting shaft such that rotation of the distal driver rotates the inner cutting shaft relative to the elongated outer shaft. The proximal driver is slidable relative to the distal drive between a more-proximal position wherein the proximal driver is engaged with the retainer cap to rotationally fix the proximal driver, thereby rotationally locking the inner cutting shaft, and a more-distal position wherein the proximal driver is disengaged from the retainer cap permitting rotation thereof thereby permitting rotation of the inner cutting shaft.

Abstract: The present disclosure relates to an arthroscopic resection device. The device includes an outer member including a hub, an inner member including a hub, the inner member housed within the outer member, a tube coupled to the outer member, and means for allowing longitudinal movement of the outer member relative to the inner member, the means coupled to the tube. A method of tissue repair and other arthroscopic resection devices are also disclosed.

Abstract: A surgical instrument for cutting a first tissue and detecting a second tissue includes a shaft, a cutting member, and a tissue monitor system. The shaft extends along a longitudinal axis and includes a shaft lumen and a shaft opening. The cutting member is disposed within the shaft lumen and configured to cyclically move from a first position to a second position relative to the shaft. The cutting member is further configured to cut a tissue portion of the first tissue for removal therefrom. The tissue monitor system is associated with at least one of the shaft or the cutting member configured to detect the second tissue distinct from the first tissue for selectively cutting and removing the first tissue relative to the second tissue.

Abstract: Provided is an ophthalmic surgery instrument that is capable of simplifying the structure of a rod-shaped portion, which is inserted into an eyeball during ophthalmic surgery, and that is suitable for excising a to-be-excised part of the eyeball. The ophthalmic surgery instrument includes a rod-shaped portion that is inserted into an eyeball during ophthalmic surgery. The rod-shaped portion has a single passage formed therein so as to penetrate from one end portion thereof to another end portion thereof. A bent portion is formed at a tip end of the rod-shaped portion. A liquid is caused to flow through the passage to flow out from a tip end opening portion of the passage or a to-be-excised part is sucked through the passage while excising the to-be-excised part with the bent portion.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) into an eye may be provided. In an exemplary aspect, the present disclosure is directed to a haptic optic management system. The haptic management system may include a housing that includes a bore and a cavity disposed in a first surface of the housing. The cavity may include a first end portion, a second end portion, and a central portion, wherein the cavity provides access to the bore through the first surface of the housing. The haptic management system may include arms coupled to the housing. The haptic management system may include edge rollers coupled to the housing.

Abstract: The invention relates to an injector assembly comprising a folding chamber which is designed to receive an intraocular lens having a lens body and two haptics, and comprising a holder, a folding wedge which is attached to the holder and is designed to be introduced into the folding chamber in an insertion direction via a folding chamber opening and to thereby fold the intraocular lens, and two sliders which are each designed to shift one of the two haptics onto the lens body via a shifting of the respective slider out of an initial position and into an end position, wherein at least one of the two sliders has a stop which is designed to abut a component attached to the holder in the initial position of the at least one slider, whereby a movement of the component is blocked and the folding wedge is thereby not permitted to fold the intraocular lens, and said stop is designed to permit the movement of the component in the end position of the at least one slider and the folding wedge is thereby permitted to fold

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. In an exemplary aspect, the present disclosure is directed to a haptic optic management system. The haptic optic management system may include a housing. The haptic optic management system may further include a plate, wherein the plate is disposed within the housing. The haptic optic management system may further include a clip that engages the plate in the housing, wherein the clip comprises a clip body and a plurality of legs that extend from the clip body.

Abstract: Intraocular lens delivery devices and methods of use.

Abstract: Delivery devices for delivering an ophthalmic device into an eye. In some embodiments the delivery devices are adapted to deliver an intraocular lens into an eye.

Abstract: An aspiration thrombectomy system for use with a vacuum source and an aspiration catheter includes a connection tubing configured to selectively connect the aspiration catheter to the vacuum source via a controllable vacuum valve. A distal pressures sensor is configured to detect pressure at the distal end within the connection tubing. An automatic controller may operate the vacuum valve to generate fluid pressure change in the connection tubing, and detect pressure profiles in the connection tubing correlated with the generated pressure changes via the distal pressure sensor. The automatic controller may determine one or more system states in the aspiration catheter or connection tubing based on the detected pressure profiles, and may operate the vacuum valve based on the determination of system state.

Abstract: A hand-held aspiration device is provided which has a relatively small suction volume along a suction path to improve responsiveness of the aspiration device when the device is activated. The device may be manually powered and may be provided without electronic controls. The device has a suction path which may be purged into a disposal enclosure to reduce the volume of material under the influence of the suction pressure during the procedure. The suction source may also be part of the hand-held unit to further reduce the suction path and suction volume.

Abstract: Methods and apparatus for retracting the dura away from a cutting tool during a laminectomy procedure. The method includes inserting a memory shape surgical sponge (patty) into an initial epidural space between the dura and the tool used to decompress (e.g., drill) the lamina. As the lamina is further decompressed, the patty tends to spring back toward its nominal position, urging the dura away from the decompression and isolating the dura from the drill.

Abstract: An IOL base compression device having an IOL towing mechanism is described.

Abstract: An intraocular lens (IOL) injector is configured for single hand operation and employs a compressed gas to provide a motive force to present an IOL to a surgical site. The IOL injector includes a mechanical brake coupled to a plunger to preclude translation of an IOL absent operator input. The mechanical brake provides for selectively varying the speed and translation of the plunger, and hence IOL during presentation of the IOL to a patient. The IOL injector can also include at least a first stop, which halts movement of the plunger at a predetermined position. The at least first stop is then moved to a passing position, thereby allowing further operator controlled translation of the plunger to present the IOL to the surgical site.

Abstract: An injector for ejecting an intraocular lens for injecting the latter into an eye or for implanting a corneal endothelial tissue, including an elongate injector body which has a piston rod passage and in which an injector piston rod having a screw thread is guided in a longitudinally displaceable manner. The injector is provided with two operating modes for the displacement of the injector piston rod and is able to be switched between the modes. The first operating mode defines an ejection operation and the second operating mode defines a screwing operation. The injector body has at least one retractable and deployable wing grip, wherein the operating mode is set to ejection operation by the deployed position and the operating mode is set to screwing operation by the retracted position. The injector piston rod includes a stop element.

Abstract: A corneal implant injector system includes an injector including a plunger slidable in a plunger housing, and a distal cartridge grabbing member engageable with an implant-holding cartridge.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. An example optic management system may include a housing having a first end and a second end and a first side extending between the first end the second end. The housing may include a cavity formed in the first side of the housing and configured to accommodate an intraocular lens, wherein the cavity comprises a first end portion, a second end portion, and a central portion. The housing may further include a bore formed in the housing, wherein a first portion of the bore extends from the first end to the cavity. The haptic optic management system may further include a ceiling disposed on the first side of the housing. The haptic optic management system may further include arms pivotably coupled to the housing in the cavity.

Abstract: Embodiments of apparatuses and methods for microfracture (e.g., forming a plurality of microfractures in a bone to encourage cartilage regeneration).

Abstract: The Nucleo-reticular Multi-cell Dual-system Eye Implant consists of a spherical structure with calculated and variable axial length depending on the needs required by the orbital eye socket, composed of a cell mesh with alternative designs that in turn, makes up the MMM System, in which suturing is provided in any technique, either in cases of evisceration or enucleation. Thanks to its multi-cell structural design, it favors its placement and reduces the risk of migration, extrusion, exposure and extraction. As it is an arrangement with structural holes, it provides a higher percentage of the volume for its vascularization; it also houses inside a Reticular Fibrovascular Core System, which has a structure based on multilevels equipped with micro-reticular tissue and an intra-level communication based on filaments; with the capacity to contain medicines and/or technology by presenting a dual-system of two screw-on pieces, being able to manufacture in different structural designs and biocompatible materials.

Abstract: Systems, methods, and apparatuses for removably attaching a drive mechanism handpiece to an intraocular lens (IOL) cartridge that folds the IOL upon removal of a cap, are provided. The IOL cartridge comprises a nozzle and a housing comprising a slide. A compartment configured to receive an IOL is disposed within the housing. An interior portion of the slide is exposed to the compartment. The nozzle is in fluid communication with the compartment. The cap covers the nozzle and the slide. The cap is configured to expose the nozzle and advance the slide to fold the IOL upon removal of the cap.

Abstract: A device for delivering a treatment medium to an eye includes a first body portion configured to be removably inserted and secured in an opening of the eye, and a second body portion supported by the first body portion. At least the second body portion includes a treatment medium, and a coating having an opening through which the treatment medium elutes out of the device.

Abstract: An IOL injector plunger having IOL compression arms is described.

Abstract: An intraocular lens insertion device which dramatically reduces the possibility that a plunger damages an intraocular lens, and which can safely and surely insert an intraocular lens into an eye is provided. An intraocular lens insertion unit comprises a lens disposing part for disposing an intraocular lens, a plunger for pushing out the intraocular lens disposed at the lens disposing part, a transition part for deforming the intraocular lens pushed out by the plunger, and a nozzle for ejecting the deformed intraocular lens. The plunger has a lens contact part for contacting the outer edge of the intraocular lens, and a protrusive part for pushing the lens contact part downward the intraocular lens by the deformation of the intraocular lens, both lens contact part and protrusive part are provided at the leading end of the plunger.

Abstract: A system and method for inserting an intraocular lens in a patient's eye includes a light source for generating a light beam, a scanner for deflecting the light beam to form an enclosed treatment pattern that includes a registration feature, and a delivery system for delivering the enclosed treatment pattern to target tissue in the patient's eye to form an enclosed incision therein having the registration feature. An intraocular lens is placed within the enclosed incision, wherein the intraocular lens has a registration feature that engages with the registration feature of the enclosed incision. Alternately, the scanner can make a separate registration incision for a post that is connected to the intraocular lens via a strut member.

Abstract: Devices, systems, and methods for performing an ophthalmic procedure in an eye are disclosed. The devices include a hand-held portion and a distal, elongate member coupled to the hand-held portion having a lumen operatively coupled to a vacuum source. A drive mechanism operatively coupled to the elongate member is configured to oscillate the elongate member. When in use, the device is configured to aspirate ocular material from the eye through the lumen. The drive mechanism retracts the elongate member with a retraction speed profile and advances the elongate member with an extension speed profile. The retraction speed profile is different from the extension speed profile.

Abstract: A device is described herein for performing capsulotomies that improves temperature uniformity and current flow around a cutting element of the device. The device includes a series of features whose geometries help remove cold and/or hot spots from the cutting element while maintaining the mechanical strength of the cutting element. In an embodiment, a device includes a cutting element and one or more electrical leads for providing an electrical discharge to the cutting element. The device further includes wire tabs configured to conductively couple an electrical lead to cutting element. Each wire tab includes a central conductive path and one or more conductive shunt paths conductively separated by one or more slots. The device further includes anchor tabs that are each associated with a slot disposed along the circumference of the cutting element and positioned to at least partially separate an anchor tab from a portion of the cutting element.

Abstract: Embodiments of the invention provide hydrodissection and/or PCO prevention or reduction in a patient undergoing eye surgery. In one embodiment, the invention is a surgical device for cutting and excising a portion of tissue, for example in performing a lens capsulotomy. A capsulotomy tip is inserted into an eye through an incision in the surface of the eye. The capsulotomy tip includes a suction cup to provide suction to the lens capsule. Then suction is applied via the suction cup to secure the capsulotomy tip to the eye. In some embodiments, after the capsulotomy tip is secured to the lens capsule, a cutting element of the capsulotomy tip is used to cut a tissue of the eye. Fluid is pushed through the capsulotomy tip and the capsulotomy tip is removed from the eye. Moreover, disclosed is an intraocular lens (IOL) to be used in conjunction with the surgical device.

Abstract: The invention relates generally to the fields of biology and health sciences. More particularly, the invention relates to compositions and methods for modulating cellular physiology and pathological processing using a combination of compounds that can be found in amniotic membrane tissue and umbilical cord tissue preparations.

Abstract: A method of controlling an eye surgical laser is disclosed for the separation of a volume body with predefined posterior and anterior interfaces from a human/animal cornea. The method including controlling the laser with a control device, the laser being configured to emit pulsed laser pulses in a predefined pattern into the cornea. The posterior and anterior interfaces of the volume body are defined by the predefined pattern and are generated by an interaction of the individual laser pulses with the cornea through photodisruption. The control device controls the laser beam such that both interfaces are generated via a continuous, uninterrupted sequence of laser pulses. A treatment device is disclosed with at least one eye surgical laser for the separation of a predefined corneal volume with predefined interfaces of a human/animal eye by photodisruption and with at least one control device for the laser(s).

Abstract: The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and/or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) into an eye may be provided. An example haptic optic management system may comprise a first cam assembly comprising a first cam body portion, an opening in the first cam body portion, and haptic folder arms disposed in the opening. The haptic optic management system may further comprise a second cam assembly positioned on one side of the first cam assembly, wherein the second cam assembly comprises a second cam body portion, an opening in the second cam body portion, and optic folders disposed in the opening. The haptic optic management system may further comprise a central plate for holding an intraocular lens in the opening of the second cam body portion, wherein the central plate is disposed between the first cam assembly and the second cam assembly.

Abstract: An IOL delivery device which has a macro movement actuator which is actuateable to move an IOL into position in the device for the IOL to be delivered, and a micro movement actuator comprising at least one pivotable member which is pivotable to deliver the IOL to the eye. The pivotable member may comprise one or more wheels that are rotatable using one's finger.

Abstract: A vibrating tissue separator suitable for use in separating a lenticule established by a femtosecond laser during a smile procedure may include a surgical implement such as a blunt spatula mounted on a handle that carries a haptic actuator for applying vibratory motion to the surgical implement. A damping arrangement may be provided to isolate the surgeons hand from the vibrations which would otherwise be transmitted through the handle. The actuator may apply a linear vibration along the axis of the handle which applies a lifting and chopping motion to the tip of a surgical implement having a bend. The tip may be suitable to the tissue being separated. For example, for SMILE lenticule separation, a blunt or semi-sharp spatula, blunted wire or loop may be used. The direction of vibration at the tip may be changed by rotating the implement in a plane other than the plane of the bend or by rotating an actuator such as an LRA with respect to the handle.

Abstract: Intraocular lens (IOL) folding devices and methods of folding an IOL or components thereof are disclosed.