With Optical Fiber Patents (Class 606/16)
  • Patent number: 6206873
    Abstract: A device and method for the removal of subcutaneous adipose layers with a laser source, optical fiber for conveying the laser ben emitted by the first source and a hollow needle f or guiding the fiber. The fiber ends in the vicinity of the end of the needle. The laser beam is generated with an intensity and a wavelength for liquefying, and maintaining liquid, the adipose cells. The laser beam from the optical fiber irradiates adipose cells in the adipose layer to transform the adipose cells into, and maintain the adipose cells as, a liquid substance.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: March 27, 2001
    Assignee: EL. EN. S.P.A.
    Inventors: Cesare Paolini, Maurizio Maida, Fabrizio Mencarelli
  • Patent number: 6200332
    Abstract: A device and method for underskin laser treatment that is minimally invasive, versatile and precise, that allows for underskin laser treatment with only minimal insertions into the area of treatment. For example, an entire area may be treated with one insertion. The device and method incorporates a standard insertion component making the system inexpensive and easy for doctors to use. In addition, the the invention allows users to get in direct contact with the treatment site, eliminating deleterious side effects encountered when treatment is administered to the skin surface. The device and method has applications in several areas of treatment. First, underskin treatment of aesthetic skin blemishes such as sagging and wrinkles can be performed with minimal external effects. Laser power is delivered directly beneath the skin, bypassing harmful exposure of the skin surface to the radiation.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: March 13, 2001
    Assignee: CeramOptec Industries, Inc.
    Inventor: Antonio Del Giglio
  • Patent number: 6179830
    Abstract: In evaporation of an organic hard tissue, a damage of a light emitting face of an optical fiber composing a laser probe is suppressed. A laser light source 13 outputs pulsate laser light of a wavelength of 1.0 &mgr;m to 5.5 &mgr;m and an output energy of 1 mJ to 2,500 mJ. The laser light is guided to a contact type handpiece 15 via a waveguide 14. The operator makes a light emitting face 17 of an optical fiber 9 of a probe 16 which is detachably attached to the tip end of the handpiece 15 contact with the surface of an organic hard tissue. In the optical fiber 9, an intermediate layer exists between a core 25 and a clad 26. The refractive index of the intermediate layer is smaller than that of the clad. In the refractive index distribution of the core 25, the refractive index is increased as moving from the center axis to the periphery. The laser light guided to the handpiece 15 passes through the optical fiber 9 of the probe 16 and is then emitted from a light emitting face 17.
    Type: Grant
    Filed: July 22, 1997
    Date of Patent: January 30, 2001
    Assignee: J. Morita Manufacturing Corporation
    Inventor: Shinji Kokubu
  • Patent number: 6176855
    Abstract: An endoscopic instrument for the therapy of the heart muscle forming channels in the heart muscle tissue by way of laser energy and including a shank tube and at least one instrumentation channel for a laser fiber disposed in axial direction within the shank tube as well as central optics parallel to the laser fiber for observing the locus of treatment. The distal end of the shank tube may be connected to a vacuum source and is designed such that the heart muscle can be restrained by partially suctioning the same against the shank end.
    Type: Grant
    Filed: October 14, 1998
    Date of Patent: January 23, 2001
    Assignee: Richard Wolf GmbH
    Inventors: Helmut Heckele, Martin Seebach, Friedrich-Wilhelm Hehrlein, Reinhard Schueck
  • Patent number: 6168591
    Abstract: Phototherapeutic instruments are disclosed having a light transmitting optical fiber with a flexible portion that facilitates passage of the instrument through a tortuous lumen within a patient and an outer support sheath slidably mounted about the fiber. In one preferred embodiment, the instrument includes a rigid light-emitting tip. The support sheath is configured to protect the more delicate optical fiber and provide support for the flexible portion of the optical fiber during penetration of the light-emitting tip into a patient's tissue. During insertion of the instrument into a tortuous lumen, the optical fiber is covered by the support sheath, allowing the light-emitting tip to deflect with ease as it travels along the tortuous lumen.
    Type: Grant
    Filed: December 16, 1997
    Date of Patent: January 2, 2001
    Assignee: CardioFocus, Inc.
    Inventor: Edward L. Sinofsky
  • Patent number: 6168589
    Abstract: A laser apparatus and method for permanently removing a plurality of hair follicles from the skin of a patient. The laser apparatus includes a housing having a single laser for sequentially emitting a series of pulses of coherent light energy having a pulse width in the range of ½ ms to 40 ms; a fiber optic bundle connected to the laser for transmitting said series of pulses of coherent light energy to the skin of a patient; and a sequence control device for controlling the laser to emit the series of pulses of coherent light energy sequentially, with a time delay of less than 100 milliseconds between the sequential pulses of the single laser. The laser apparatus includes a handpiece assembly for holding a section of the fiber optic bundle for directing the series of pulses of coherent light energy to the same spot of the patient's skin to remove the plurality of hair follicles, veins, or capillaries.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: January 2, 2001
    Inventor: Edward L. Tobinick
  • Patent number: 6165171
    Abstract: A laser apparatus and method for permanently removing a plurality of hair follicles from the skin of a patient. The laser apparatus and method includes a housing having at least first and second lasers contained therein for emitting at least first and second pulses of coherent light energy having a pulse width in the range of 1/2 ms to 40 ms; a first fiber optic bundle connected to the first laser for transmitting at least a first pulse of coherent light energy to the skin of a patient, and a second fiber optic bundle connected to the second laser for transmitting at least a second pulse of coherent light energy to the skin of a patient; and a sequence control device for controlling at least first and second lasers to emit at least first and second pulses of coherent light energy either sequentially or simultaneously, with a time delay of less than 100 milliseconds between the sequential pulses of the first and second lasers.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: December 26, 2000
    Inventor: Edward L. Tobinick
  • Patent number: 6162214
    Abstract: Apparatus and method for creating pathways in tissue and destroying the cored tissue to avoid release of the cored tissue within the body. The apparatus has a coring mechanism and a tissue vaporization mechanism. The apparatus is useful in creating revascularization pathways in the myocardium. The apparatus and methods are adaptable for either surgical or percutaneous procedures.
    Type: Grant
    Filed: October 30, 1998
    Date of Patent: December 19, 2000
    Assignee: Eclipse Surgical Technologies, Inc.
    Inventors: Richard L. Mueller, Alexander Khairkhahan
  • Patent number: 6162052
    Abstract: A laser handpiece is configured by a main body 13 and a laser probe 10 mounted on the tip end of the main body 13. The laser probe 10 has an emission fiber 12. A laser beam generated by a laser beam source is emitted from an emission end portion 22 of the emission fiber 12. The emission end portion 22 of the emission fiber 12 is formed into a circular conical shape. The laser beam emitted from the emission end portion 22 contains a first laser beam which is emitted in the axial direction of the emission fiber 22, and a second laser beam which is emitted in a ring-like shape in a radial direction of the emission fiber 12.
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: December 19, 2000
    Assignee: J. Morita Manufacturing Corporation
    Inventor: Shinji Kokubu
  • Patent number: 6159236
    Abstract: The invention relates to a medical device including a tube and expandable member and one or more light sources disposed in an elongated member disposed in the tube. The light sources emit energy for photodynamic therapy through a window to the treatment area. The treatment device may further include a heat and/or light dissipating layer, such as a layer of gold alloy paint, or other light blocking material.
    Type: Grant
    Filed: January 28, 1999
    Date of Patent: December 12, 2000
    Assignee: Advanced Photodynamic Technologies, Inc.
    Inventor: Merrill A. Biel
  • Patent number: 6152919
    Abstract: A resectoscope for laser coagulation and cutting of prostatic or bladder tissue. The resectoscope also uses a mechanical cutting element having sharp blades rotating at high speed to further cut the coagulated lased tissue. The combination of coagulating/cutting using the laser energy with further cutting by mechanical means allows the surgeon to perform this procedure more quickly and efficiently, and permits retrieval of the resected tissue for pathological examination.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: November 28, 2000
    Assignee: Canox International, Ltd.
    Inventor: Said I. Hakky
  • Patent number: 6149645
    Abstract: A laser apparatus for permanently removing a plurality of hair follicles or blood vessels from the skin of a patient. The laser apparatus includes a housing having first and second lasers contained therein for emitting at least first and second pulses of coherent light energy; first and second fiber optic bundles connected to the first and second lasers, respectively, for transmitting the pulses of coherent light energy from the first and second lasers; the first and second fiber optic bundles connected to a common fiber optic bundle for combining and transmitting at least first and second pulses of coherent light energy from each of the first and second lasers through the common fiber optic bundle; and a sequence control device for controlling the first and second lasers to emit at least first and second pulses of coherent light energy either sequentially or simultaneously, with a time delay of less than 100 milliseconds between the sequential pulses from the first and second lasers.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: November 21, 2000
    Inventor: Edward L. Tobinick
  • Patent number: 6143018
    Abstract: A process is disclosed for thermally obliterating biological tissues by laser radiation introduced into the tissue by means of an optical waveguide. The laser radiation is scattered by means associated with the radiation output surface of the optical waveguide. A biocompatible, medium to highly visquous liquid which does not substantially absorb the laser radiation but scatters it, is injected into the tissue, forming a scattering fluid deposit around the radiation output surface which is not separated from the tissue and which allows the tissue to be heated in a controlled manner.
    Type: Grant
    Filed: March 28, 1996
    Date of Patent: November 7, 2000
    Assignees: CeramOptec GmbH, Huttinger GmbH
    Inventors: Jurgen Beuthan, Andre Roggan, Gerhard Muller
  • Patent number: 6138046
    Abstract: A dosimetry probe for monitoring light irradiation dosages and for providing irradiance measurements to monitor the application of light during a phototherapy procedure. The dosimetry probe includes a light delivery optical fiber operable to transmit optical radiation to target tissue and a plurality of dosimetry optical fibers substantially coextensive with the light delivery optical fiber, the distal ends of each of the dosimetry optical fibers arranged at a different axial distance from the light delivery optical fiber to provide irradiance measurements at a number of different axial distances. The dosimetry probe may include a safety feedback optical fiber to monitor the intensity of the treatment light independent of the influence of the optical properties of the target tissue. The dosimetry probe may also include a source dosimetry optical fiber for carrying a modulated dosimetry light signal, which can be selectively detected by means of frequency lock-in technology.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: October 24, 2000
    Assignee: Miravant Medical Technologies, Inc.
    Inventor: Brian Dalton
  • Patent number: 6135996
    Abstract: A controlled advancement laser ablation device is provided for precise ablation of body matter. The laser ablation device includes a handle portion having proximal and distal openings and a fiber advancing device having a stationary member and a movable member. The movable member is movable towards and away from the stationary member. A fiber casing is included having proximal and distal ends. The distal end is secured to the proximal end of the handle portion and the proximal end is secured to the stationary member. At least one optical fiber is included having proximal and distal ends. The distal end is extendible through the handle portion and a portion of the fiber, defined between the proximal and distal ends, is secured to the movable member. A laser energy generator is optically connected to the proximal end of the optical fiber. The handle portion includes a self-biasing advancing mechanism.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: October 24, 2000
    Assignee: Baxter International, Inc.
    Inventors: Michael S. Kolesa, James Correia, Oleg Shikhman, Thomas J. Pacala, Barton C. Thompson
  • Patent number: 6132423
    Abstract: A method and catheter system for irradiating a body lumen wall which comprises providing an elongated, flexible radiation transmission member having an emitting portion at its distal end, advancing the emitting portion to an area adjacent the wall defining the patient's body lumen to be treated by irradiation, and directing radiation through the transmission member while moving the transmission member to cause the emitting portion to irradiate a length of the wall of the body lumen. The transmission member may be rotated independently or in conjunction with longitudinal movement to achieve either selective or uniform irradiation of the wall defining the body lumen. In one embodiment, this invention comprises an elongated flexible shaft, having an inflatable member disposed at the distal end. A radiation transmission member having an emitting portion on its distal end is slidably disposed within the elongated shaft so that the emitting portion resides within the inflatable member.
    Type: Grant
    Filed: July 21, 1997
    Date of Patent: October 17, 2000
    Assignee: Eli Lilly and Company
    Inventors: Michael Aita, Michael Buchin
  • Patent number: 6132451
    Abstract: An optical fiber device for forming channels within a wall of a patient's heart, and particularly the epicardium, which has an elongated optical fiber, a probe tip secured to the distal end of the optical fiber and an outer support tube secured to the proximal portion of the probe tip and a distal portion of the optical fiber proximal to the probe tip. A handle is described for a flexible optical fiber device which greatly facilitates delivery of the distal end of the optical fiber device to a desired location on the exterior of a patient's heart.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 17, 2000
    Assignee: Eclipse Surgical Technologies, Inc.
    Inventors: Sam G. Payne, Randy J. Kesten, Paul Kawula
  • Patent number: 6129721
    Abstract: A medical laser treatment device comprises a handpiece having a handpiece body and a laser probe to be attached to the handpiece body, a laser light source, and a light transmission member which guides laser light to the handpiece. The laser probe has a fiber probe having an emission face through which the laser light is emitted to an irradiation region, an annular protection tube which covers the peripheral face of the fiber probe, and a holder which holds the fiber probe and the protection tube. The protection tube has a curved part extending with being curved. A first fiber curved part is formed in the fiber probe by passing the fiber probe through the protection tube. A second fiber curved part having a radius of curvature is smaller than that of the first fiber curved part is disposed in a tip end portion of a fiber probe.
    Type: Grant
    Filed: June 2, 1998
    Date of Patent: October 10, 2000
    Assignees: J. Morita Manufacturing Corporation, Fujikura Ltd.
    Inventors: Kenzo Kataoka, Masaki Odaka, Akira Yuba, Koichi Yamazaki, Takashi Tsumanuma, Keiji Kaneda
  • Patent number: 6126653
    Abstract: A laser therapy system and method of cutting and vaporizing a tissue body which includes a fiber optic which is inserted into the lumen of a catheter and operable between an extended position wherein a distal end portion of the fiber optic is positioned to cut and vaporize a tissue body and a retracted position wherein the fiber optic is received within the lumen of the catheter. The catheter incorporates at a distal end portion a means for removing attached tissue fragments and the like from the distal end portion of the fiber optic such that tissue fragments stuck to the distal end portion of the fiber optic can be removed while the catheter and fiber remain at the treatment site. This improved system eliminates the need to completely remove the fiber optic during the cutting and vaporization procedure in order to remove the fragments and debris.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 3, 2000
    Inventor: John H. Hajjar
  • Patent number: 6120498
    Abstract: An aspirating handpiece for laser surgical applications, includes an elongated hollow cylindrical probe member (22). A proximal end (24) of the probe member is arranged such that aspiration means can be connected therewith, and a distal end (26) of the probe member has an aperture therein for receiving matter to be aspirated. An elongated optical fiber (50) extends along the probe member with the distal end (59) of the fiber proximate the aperture therein. The proximal end (52) of the fiber is arranged to receive laser radiation. The probe member has an inside diameter progressively increasing from the distal end thereof to the proximal end thereof.
    Type: Grant
    Filed: March 5, 1998
    Date of Patent: September 19, 2000
    Inventors: Mahendra G. Jani, J. Michael Yarborough, George Marcellino, Robert W. Snyder, Donald J. D'Amico
  • Patent number: 6113589
    Abstract: A device for use in laser induced interstitial thermotherapy (LITT) is provided which includes a fiber for coupling to a laser energy source and an emitting element having a proximal end coupled to the fiber and a distal end for positioning adjacent to the surface receiving LITT, the emitting element radially emitting light whose intensity is controllable along its longitudinal length. In a preferred embodiment, the surface of the emitting element is roughened to achieve a power scattering function.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: September 5, 2000
    Assignee: Laser Industries Ltd.
    Inventors: Uri Levy, Orit Frankel, Ytzhak Rosenberg, Raphi Seror
  • Patent number: 6102905
    Abstract: A phototherapy device which can include an optical fiber having a perfluorinated polymer outer buffer coating, and an optical element, such as a GRIN lens or a mirror, disposed at its distal end. A tubular housing encases the optical element and is thermally bonded to at least a portion of the buffer. The component elements of the device can be constructed of materials having similar thermal characteristic to inhibit the effect of heat cycling on the device. In addition, the materials of the device, and in particular the housing, can be selected to inhibit wear and scrapping of the lumen of the delivery instrument during use. A marker band can be positioned about the optical fiber to facilitate viewing of the phototherapy device in-vivo.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: August 15, 2000
    Assignee: CardioFocus, Inc.
    Inventors: Lincoln S. Baxter, Edward L. Sinofsky, Norman Farr
  • Patent number: 6099498
    Abstract: A probe having the ability to deliver cardioplegia solution to the coronary sinus under direct visualization and to provide venous drainage from the right atrium for cardiopulmonary bypass. The probe has an elongate tubular member, including a distal end, a proximal end, and a lumen. A membrane, optionally perforated, mounted within the lumen of the tubular member partitions the lumen and is removable or penetrable by a cardioplegia catheter. The distal end comprises a toroidal balloon or a circumferential recessed vacuum manifold. A vacuum port communicates with the distal end of the tubular member or the vacuum manifold. Methods of using the cardioplegia access view probe for catheterization of the coronary sinus and for venous return as herein described are also disclosed.
    Type: Grant
    Filed: September 2, 1998
    Date of Patent: August 8, 2000
    Assignee: Embol-X, Inc
    Inventor: Bruce Addis
  • Patent number: 6096028
    Abstract: Various embodiments of optical fiber cables and laser probes are disclosed for providing multi-spot laser beams from a single laser beam source. This permits time-intensive but repetitive laser surgical procedures such as panretinal photocoagulation to be performed with increased accuracy and in a fraction of the time currently allotted for such procedures.
    Type: Grant
    Filed: July 29, 1998
    Date of Patent: August 1, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Sina Bahmanyar, Mark S. Jones
  • Patent number: 6080146
    Abstract: A method and apparatus for the removal of, and at least inhibiting the regrowth of, unwanted hair by applying optical radiation to the follicle, including the hair shaft therein, of an energy, a duration and wavelength to enhance the optical absorption characteristics of at least some component, (i.e., melanosomes, tissue, etc.) of the follicle without appreciably damaging skin outside the follicle; and subsequently applying optical radiation to the follicle of a wavelength which is more readily absorbed by the components of the follicle having optical absorption characteristics enhanced during step (a) then by unenhanced components and of an energy and duration to heat such enhanced components sufficiently to substantially destroy the follicle.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: June 27, 2000
    Inventors: Gregory Altshuler, Michael Smotrich
  • Patent number: 6066129
    Abstract: A medical laser adapted to be controlled remotely from the main operating console, and more particularly, a handpiece held by the surgeon which includes one or more remote controls for actuating and controlling the operation of a medical laser.
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: May 23, 2000
    Inventor: Dean W. Larson
  • Patent number: 6066128
    Abstract: Various embodiments of optical fiber cables and laser probes are disclosed for providing multi-spot laser beams from a single laser beam source. This permits time-intensive but repetitive laser surgical procedures such as panretinal photocoagulation to be performed with increased accuracy and in a fraction of the time currently allotted for such procedures.
    Type: Grant
    Filed: February 1, 1999
    Date of Patent: May 23, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Sina Bahmanyar, Mark S. Jones
  • Patent number: 6063109
    Abstract: A system composed of a device 4 for the coherent amplification of electromagnetic oscillations by means of induced emission through a solid element, crystals or glasses doped with neodymium, semiconductor diodes or liquids or gases, whereby the electromagnetic oscillations emerging from the device are conducted through a cable or optical fiber cable 2 in order to influence a biological system, especially a human body or an animal body 11. The cable 2 has an outlet opening 7 and the oscillations emerging from the cable 2 are conducted through a solid element, a mixture or a liquid or gaseous solution 8 in order to influence the biological system 11, whereby the solid element, the mixture or the liquid or gaseous solutions contain mineral, plant, animal or human extracts or products or else toxins as admixtures.
    Type: Grant
    Filed: September 17, 1998
    Date of Patent: May 16, 2000
    Inventor: Thomas Ruschke
  • Patent number: 6059776
    Abstract: A combined mechanical cutter and laser function surgical instrument, constructed with; a handle housing and a disposable tip assembly removably mounted to the handle housing. The disposable tip assembly has a hollow tube with a proximal and a distal end, a stationary jaw mounted to the distal end of the hollow tube, a movable jaw which pivots relative to the stationary jaw and a actuating mechanism coupled to the movable jaw for moving the movable jaw, the actuating mechanism being driven from linkage in the handle housing mounted to the proximal end of the hollow tube. Quick disconnects are mounted on the proximate end of the hollow tube to engage the handle housing and a laser energy conductive optic fiber extends through the hollow tube and mounted to the stationary jaw. A laser energy dispensing tip member is mounted on and insulated from the stationary jaw and is connected to the optic fiber to transport laser energy from a remote laser energy generator.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: May 9, 2000
    Inventor: Dom L. Gatto
  • Patent number: 6053909
    Abstract: An Rf energy applicator with a working end that carries a bi-polar Rf electrode system for creating a Rf-tissue interaction or ionothermal effect in subsurface tissue (a first ionothermal system) which effect is focused by concurrent actuation of a photonic tissue-sensitizing system or photoconductance system (a second ionothermal system). The photonic energy system is adapted to create a "lens electrode" in subsurface tissue that enhances the targeted tissue's conductance of Rf current which serves as a means of focusing Rf ionothermal effects at a subsurface level. A dosimetry control system is provided that controls the dose and timing of Rf energy delivery as well as the dosimetry of photonic energy delivery. The ionothermal applicator has a handle portion coupled a tubular extending member. The distal termination of the probe has at least one pair of opposing conductive electrodes in a spaced relationship around a perimeter of the distal termination of the extending member.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: April 25, 2000
    Inventor: John H. Shadduck
  • Patent number: 6050990
    Abstract: Methods of applying laser light to the skin, and apparatus therefor, include methods for removing hair, for synchronizing hair growth, for stimulating hair growth, for treating Herpes virus, for reducing sweat and body odor, for in situ formation of a chromophore in hair ducts, for reducing light loss at the skin surface, for grafting of hair stem cells, and for removing keloid or hypertrophic scars. The hair removal methods include controlling the proportions of photomechanical and photothermal damage by selection of laser parameters, chromophore particle size and/or pulse duration, with optional dynamic skin cooling. Additional hair removal methods include infiltrating a photoactivated drug into hair ducts and exposing the skin to sunlight or administering an anti-proliferative agent into hair ducts, for example, by encapsulating the anti-proliferative agent in a slow release vehicle.
    Type: Grant
    Filed: December 4, 1997
    Date of Patent: April 18, 2000
    Assignee: ThermoLase Corporation
    Inventors: Nikolai I. Tankovich, Kurt A. Dasse, David H. Fine, Paul W. Fairchild, Zhong-Quan Zhao, Mike Lefebvre, John Lee, Jr., Jonathan L. Rolfe, Susan Murrell, Allen Hunter, II, Amanda J Reynolds, Vladimir G. Kolinko
  • Patent number: 6039729
    Abstract: A medical instrument, such as a cautery device, wherein bleeding is stopped or prevented by clamping the bleeding site with a dedicated forceps and using a highly localized heat source such as a fiber-coupled laser. The laser energy quickly and locally heats up the tip of the forceps cautery device. The tip of the forceps device has minimum thermal mass and is thermally insulated from the body of the forceps. In this present invention, there is no electrical current flowing through or into the tip of the instrument, and can therefore be safely used in any part of the body including around the heart or the brain. When combined with a small semiconductor laser, the device is battery operated, self-contained and hand-held, and can therefore be used in any environment including outdoors.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: March 21, 2000
    Assignees: Cynosure, Inc., N. E. Medical Center Hospitals
    Inventors: Frederick M. Durville, Raymond J Connolly, John C Lantis, Robert H Rediker, Steven D. Schwaitzberg
  • Patent number: 6039726
    Abstract: The invention includes the use of a beam homogenizer (scattering surface) at the input aperture of a tapered optical fiber to avoid hot spots (2) in the tapered section which would otherwise destroy the fiber (10).
    Type: Grant
    Filed: October 15, 1996
    Date of Patent: March 21, 2000
    Assignee: Nanoptics, Inc.
    Inventors: Aaron Lewis, Daniel Palanker, Igor Turovets
  • Patent number: 6036685
    Abstract: A method of visualizing and treating the heart by providing a balloon end contact scope with a main lumen, an essentially transparent contact viewing portion, and integral laser delivery means or other equipment channel suitable for viewing the heart; precisely positioning the contact viewing portion in contact with a portion of the heart adjacent the position to be viewed; and visualizing the heart. The scope may have a gripping surface particularly suitable for percutaneous use. For MIS use, the scope tents the pericardial sac. The method can be used to place a guide wire or tether to the heart to locate a fluoroscopic or other visualization means or to perform additional visualization, fluoroscopic marking or other interventional procedures. The method also comprises the step of delivering laser energy to a portion of the heart to effect transmyocardial revascularization.
    Type: Grant
    Filed: February 18, 1998
    Date of Patent: March 14, 2000
    Assignee: Eclipse Surgical Technologies. Inc.
    Inventor: Richard L. Mueller
  • Patent number: 6036683
    Abstract: A process is described for changing the curvature of the cornea in which the light of a light source is focused in the cornea with a wavelength of approximately 1.5 .mu.m to 6 .mu.m so that the collagenic tissue shrinks selectively. The invention is characterized in that the light is applied continuously at such a power that, although a temperature is reached which leads to irreversible coagulations of the collagenic tissue, the temperature within the coagulated region rises to values at which there is not yet a relaxation of the tissue.
    Type: Grant
    Filed: January 2, 1997
    Date of Patent: March 14, 2000
    Assignee: G. Rodenstock Instruments GmbH
    Inventors: Benedikt Jean, Thomas Bende, Theo Ottrup, Michael Mataliana, Rudolf Walker
  • Patent number: 6033371
    Abstract: A method and apparatus for dilating blood vessels in vasospasm through the use of high frequency wave, e.g., hydraulic or acoustic waves. The invention is suitable to treat any vasospasm, including any vasospasm intractable to medication, including cerebral vasospasm, which currently is not susceptible to any mechanical or chemical treatments. The apparatus for dilating blood vessels includes a catheter having a fluid-filled lumen, a wave generator arranged within the catheter lumen for generating a wave front that propagates through the fluid in the lumen and is transmitted from the distal end of the catheter to propagate through the fluid in the blood vessel, and an energy source connected to the wave generator to provide energy to produce the wave front.
    Type: Grant
    Filed: August 26, 1997
    Date of Patent: March 7, 2000
    Assignee: The General Hospital Corporation
    Inventors: Ralph De La Torre, Kenton W. Gregory
  • Patent number: 6027524
    Abstract: A device for delivering phototherapeutic light to the nipple and surrounding tissue of a breast. Many mastectomy procedures for patients with breast cancer require removal of the nipple. Thus, for the best aesthetic result, post-operative augmentation or reconstruction of the breast includes the implantation of an artificial nipple. The present device and method permits a more conservative mastectomy to be performed while reducing the risk of recurrence wherein cancerous and pre-cancerous tissue in the nipple and surrounding aureole tissue are treated by illuminating the tissue with phototherapeutic light. The tissue is first perfused with a photosensitizer which accumulates therewithin. An embodiment of the device, which includes a rigid or semi-rigid hemispherical shell for structural stability, is attached to the breast. The device includes a transparent flexible aperture which is designed to fit snugly against the outer surface of the nipple and surrounding tissue.
    Type: Grant
    Filed: March 19, 1998
    Date of Patent: February 22, 2000
    Inventor: Michael G. Petit
  • Patent number: 6027498
    Abstract: The flow of a biological fluid to an organ is computer controlled so that natural variation of such flow is simulated. Specifically described are control of a blood pump flow output during CPB to mimic normal pulsatile blood flow from the heart and control of a ventilator output To mimic normal breathing of healthy lungs. A pattern of variation over Time of instantaneous flow of a biological fluid to an organ of a mammalian species is established, a variable control parameter for regulation of flow of the biological fluid to the organ is generated in accordance with the pattern, and the flow of biological fluid is to the organ is controlled in accordance with the variable control parameter.
    Type: Grant
    Filed: January 6, 1997
    Date of Patent: February 22, 2000
    Assignee: University of Manitoba
    Inventors: William Alan C. Mutch, Gerald Robin Lefevre
  • Patent number: 6024738
    Abstract: A laser catheter for the treatment of lesions and plaque deposits in arteries and other narrow paths having a radiation assembly affixed to a flexible conduit. The conduit generally includes multiple lumens for the passage of an optical fiber, a guide wire, a cooling medium therethrough, or fluid for inflating an angioplasty balloon. The radiation assembly is of short longitudinal profile and includes a generally spherical laser contact member retained within a housing, the latter affixed to the flexible conduit. The radiation assembly provides a dual-mode ablation/melting treatment regime. A longitudinal channel is provided through and along one side of the contact member thereby to permit guide wire positioning of the laser catheter while routing the guide wire away from the laser energy to avoid damage thereto. A balloon, in fluid communication with a catheter lumen, may be positioned rearwardly of the radiation assembly for secondary balloon angioplasty operations.
    Type: Grant
    Filed: July 11, 1997
    Date of Patent: February 15, 2000
    Assignee: Surgical Laser Technologies, Inc.
    Inventors: Norio Daikuzono, John Vanden Hoek, Kenneth P. Cook, Robert Bross
  • Patent number: 6022345
    Abstract: A laser treatment method and apparatus is provided which facilitates the grafting of hairs on the skin of a living human. The methodology involves a carefully designed treatment protocol utilizing a modified optical apparatus. The apparatus is a modified erbium-based laser system, designed for optimal therapeutic selectivity.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: February 8, 2000
    Inventors: Iain D. Miller, Karolj Nemes
  • Patent number: 6015405
    Abstract: A surgical instrument for creating holes of a predetermined diameter and depth in body tissue comprises a tubular catheter having a compression spring affixed at its distal end and attached to the distal end of that spring is a tissue ablating device which may, for example, comprise an electrosurgical monopolar or bipolar electrode that is connected by conductors extending through the lumen of the catheter to an electrosurgical generator at its proximal end. When the instrument is brought in contact with target tissue with a force sufficient to compress the coils of the spring against one another and then ablating energy applied, tissue will be removed as the spring is allowed to expand out to its uncompressed length. The depth of the hole thus created is equal to the difference between the lengths of the spring when compressed and uncompressed. If desired, a suitable drug can be delivered into the thus created hole via a lumen in the catheter.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: January 18, 2000
    Assignee: Tricardia, L.L.C.
    Inventors: Robert S. Schwartz, David R. Holmes, Robert A. VanTassel
  • Patent number: 6011889
    Abstract: A device for use in laser surgical procedures for moving axially an optical fiber element that is connected at its proximal end to a source of laser energy. The distal end of the fiber elements with a cooperating piercing tip member has a tapered configuration so that it is capable of penetrating soft tissue of membrane such as the myocardium or epicardium of a human heart during the revascularization procedure. Various combinations of bundled optical fiber elements are disclosed which provide different tapered distal end designs that can be used in various surgical procedures.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: January 4, 2000
    Assignee: Eclipse Surgical Technologies, Inc.
    Inventors: Steven A. Daniel, Timothy C. Reynolds, Zachary E. Owyang
  • Patent number: 6004315
    Abstract: An optical fiber device includes a polymeric optical fiber having a proximal end for coupling to a source of light, and a diffusing region. The polymeric optical fiber includes a core and a cladding around the core. The diffusing region includes a length of the polymeric optical fiber in which the cladding is partially removed to expose the core and in which the exposed core and the remaining cladding have a roughened surface for outwardly diffusing light carried through the polymeric optical fiber. The diffusing region is preferably formed by abrasion, for example by directing a particle jet at the optical fiber while rotating and translating the optical fiber with respect to the particle jet. The particle jet may include microscopic glass beads which roughen the optical fiber core. The density of scattering sites may be varied along the length of the diffusing region to produce a desired light output pattern.
    Type: Grant
    Filed: September 16, 1996
    Date of Patent: December 21, 1999
    Assignee: Focal, Inc.
    Inventor: Michael G. Dumont
  • Patent number: 5999678
    Abstract: A drug delivery apparatus for dispensing a predetermined amount of one or more drugs into a laser created opening in the human body, the apparatus consisting of a laser delivery means such as an optical fiber or fiber bundle, a drug conduit which transfers the one or more drugs, drug solutions or other substances to the distal end of the laser delivery means, and the laser delivery means disposed essentially coaxially with the drug conduit. Laser delivery means is used to create a TMR channel or other opening in the body. Dispensed drug or other substance travels through the drug conduit and emanates from the drug conduit to be delivered into the TMR channel or other laser created opening. Drug is dispensed by manually or automatically activating an electric motor which actuates a piston element. A method of use is also disclosed.
    Type: Grant
    Filed: December 27, 1996
    Date of Patent: December 7, 1999
    Assignee: Eclipse Surgical Technologies, Inc.
    Inventors: Douglas Murphy-Chutorian, Richard L. Mueller, Stuart D. Harman, Steve A. Daniel, Larry Witham, Bruce Richardson
  • Patent number: 5997570
    Abstract: A method is disclosed for introducing a stent inside the body of a patient. The stent is made of a material that cures due to the action of light. A catheter having an inflatable balloon adjacent its distal end is provided. Also provided is a light conductor comprising a transparent, elongated member, the elongated member having a smooth, outer wall along most of its length with a portion of the light conductor within the balloon having a rougher outer wall to allow light to project laterally outwardly through the wall. The balloon carries on substantially its entire surface a partially reflective layer to permit the light to be partly reflected and partly transmitted through the same portions of the wall of the balloon. The stent is cured by providing light to the light conductor.
    Type: Grant
    Filed: September 9, 1997
    Date of Patent: December 7, 1999
    Assignee: Cordis Corporation
    Inventors: Hendrikus Cornelis Geert Ligtenberg, Marcel Gerhard Haan, James Ernest Leone
  • Patent number: 5993442
    Abstract: The present invention is for the purpose of providing a medical laser irradiation apparatus which applies laser beams of two or more wavelengths, incapable of transmitting in a quartz optical fiber, through the use of an optical fiber cable, with this medical laser irradiation apparatus being easy to handle and producible at a low cost, and also capable of making irradiation through the use of a relay optical fiber cable comprising a quartz optical fiber. For this purpose, this apparatus is composed of a laser irradiation apparatus to output laser beams of a plurality of wavelengths capable of being transmitted by a quartz optical fiber, and two or more kinds of irradiation optical fiber cables including an optical fiber cable having a quartz optical fiber and containing a solid state laser medium and/or a nonlinear optical crystal at its tip portion.
    Type: Grant
    Filed: March 24, 1998
    Date of Patent: November 30, 1999
    Assignee: Termuno Kabushiki Kaisha
    Inventor: Shigeru Omori
  • Patent number: 5993072
    Abstract: An assembly of connectors adapt multiple optic fiber illuminators of microsurgical instruments for use with a variety of different available light sources.
    Type: Grant
    Filed: April 17, 1996
    Date of Patent: November 30, 1999
    Assignee: The Johns Hopkins University
    Inventors: Eugene de Juan, Jr., Gregg D. Scheller, Michael D. Auld, Dyson Hickingbotham
  • Patent number: 5993439
    Abstract: A lens shield system for shielding a laser source of a system used for collecting capillary blood or fluid from skin, the lens shield comprising a strap apparatus releasably emplaceable around a member of a living being, the member having skin thereon and blood therein, and a lens shield member connected to the strap and disposed for receiving and for transmission therethrough of a laser beam from the laser source directed at the skin. A removable lens shield for shielding a laser source of a collection system used for perforating skin and collecting blood or fluid therein or therebeneath, the collection system in a housing, the lens shield comprising a body sized and configured for removable emplacement in the housing of the collection system between the laser source and the skin, and a window in the body through which the laser beam is transmissible prior to contacting the skin. A method for collecting fluid from a living being has been invented which uses the devices mentioned above.
    Type: Grant
    Filed: April 22, 1997
    Date of Patent: November 30, 1999
    Assignee: Cell Robotics, Inc.
    Inventors: David J. Costello, Michael A. Wolf, Kenneth G. Schalhoub, Ronald K. Lohrding, Aleksei Y. Dergatchev, Warren E. Parkhurst, Valeri G. Polushkin, Sergei A. Kokhanovsky
  • Patent number: 5989283
    Abstract: An irradiation device, especially for the cosmetic, diagnostic and therapeutic application of light, having an incoherent light source and a reflector that surrounds the light source and has a slit-like opening defining the direction of the radiation. Arranged in the beam path of the light source is a spectral dispersion element. In the output beam path of the spectral dispersion element, a fiber-optic cross-sectional transformer is disposed in such a way that its circular end is located opposite the spectral dispersion element. The fiber-optic cross-sectional transformer and the spectral dispersion element are movable relative to each other.
    Type: Grant
    Filed: September 25, 1997
    Date of Patent: November 23, 1999
    Assignee: Heinrike Wilkens
    Inventor: Jan Henrik Wilkens
  • Patent number: 5976175
    Abstract: A fiber optic laser conducting probe is used for photodynamic therapy. In this fiber optic laser conducting probe, an optical fiber has an end used for conducting a pulse laser beam. The laser beam is conducted through the optical fiber and irradiated from the end. A end tip is made of polyamide resin. The end tip has a hollow portion, and is attached to the end of the optical fiber such that the pulse laser beam can be irradiated through the end of the optical fiber, through the hollow portion and through the end tip.
    Type: Grant
    Filed: June 18, 1996
    Date of Patent: November 2, 1999
    Assignees: Lederle (Japan), Ltd., Hamamatsu Photonics K.K., Moritex Corp.
    Inventors: Toru Hirano, Akio Tanaka, Masami Ohsawa, Takuya Kohno