Abstract: The present disclosure provides devices, systems, and methods for spinal cord stimulation. In some exemplary embodiments, a lead is provided. In one exemplary embodiment, the lead includes a paddle and an electrode array distributed in the paddle. The electrode array includes a first column of electrodes and a second column of electrodes. The first column of electrodes and the second column of electrodes are symmetric about the midline of the paddle. The first column of electrodes includes a first electrode, a second electrode, and a third electrode. The second column of electrodes includes a fourth electrode corresponding to the first electrode, a fifth electrode corresponding to the second electrode, and a sixth electrode corresponding to the third electrode. A vertical inter-electrode distance between the first electrode and the second electrode is larger than that between the second electrode and the third electrode.

Abstract: Methods and systems are disclosed for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to electrical energy. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.

Abstract: A medical electrical lead and methods of implanting medical electrical leads in lumens. Leads in accordance with the invention employ preformed biases to stabilize the lead within a lumen or lumen and to provide feedback to lead implanters.

Abstract: Disclosed herein are systems and methods for nerve conduction block that can involve the delivery of relatively high amounts of charge safely to tissue. Such systems and methods can include control systems for safely monitoring a direct current electrode system, including delivering direct current via an electrode lead to a target tissue of a patient; measuring the driving voltage across the electrode; comparing the driving voltage across the electrode to predetermined threshold range values; measuring the body impedance; determining a voltage drop across the lead from the body impedance measurement; and adjusting the driving voltage to maintain the voltage drop across the lead within a predetermined voltage range.

Abstract: A wearable garment includes a compression fabric with at least one electrode coupled to the compression fabric or sewn into seams of the wearable garment. The electrode includes a first layer comprising a metal integral conductive silicone rubber material configured to lay proximate to a wearer of the garment. The electrode may also include a second layer including a conducting metal sheet and a conductive lead coupled to the second layer. A non-conducting layer is configured to lay proximate to the compression fabric.

Abstract: A method of non-thermally ablating undesirable tissue in the body by application of pulsed, bipolar, instant charge reversal electrical fields of sufficient energy to cause complete and immediate cell membrane rupture and destruction. Energy is delivered through radio frequency pulses of particular frequencies, wave characteristics, pulse widths and pulse numbers, such that enhanced physical stresses are placed on the cell membrane to cause its immediate and complete destruction thereby spilling the entire cell content and membrane constituents into, the extracellular space without denaturing proteins so as to enable an immunological response to destroy and remove the target tissue and similarly marked tissue elsewhere in the subject.

Abstract: A method of treating an overactive bladder condition includes providing a stimulation device having a generator enclosing a primary cell that is coupled to circuitry, and a lead coupling an electrode assembly to the generator, where the circuitry is operable to generate a stimulation signal with a duty cycle of between 0.1% and 2.5% and a total average current drain from the primary cell of between 0.1 ?A and 5 ?A, with the total average current drain including a background current plus a stimulation current weighted by the duty cycle; forming an incision in skin of a patient diagnosed with the overactive bladder condition; implanting the stimulation device in the patient by inserting the stimulation device into the incision in the skin of the patient; and closing the incision.

Abstract: This invention corresponds to an electrical and magnetic tissue stimulation device comprising a multi-source distribution circuit, a decoupled output stage circuit connected to the multi-source distribution circuit and to a control unit; the control unit is connected to the multi-source distribution circuit and to the decoupled output stage circuit, where the control unit generates PE and Out outputs for electrical and magnetic stimulation of a tissue. The invention also has a multi-source distribution circuit that comprises a control unit connected to a source output selector. A voltage regulator circuit is connected to a current limiter. The current limiter is connected to a capacitor, to a capacitor bank and to the source output sector, wherein the control unit controls the source output selector by means of an output control signal bus, the source output selector connects or disconnects one or more capacitors from the capacitor bank.

Abstract: An example of a system for delivering neurostimulation energy may include a programming control circuit and a user interface. The programming control circuit may be configured to generate stimulation parameters according to a neurostimulation program including a pattern of interferential stimulation configured to effect asynchronous and/or non-regular activation of nerve fibers by simultaneously delivering a first stimulation current having a first waveform with a first frequency using a first electrode configuration and a second stimulation current having a second waveform with a second frequency using a second electrode configuration.

Abstract: An automated external defibrillator (AED) system includes shock generating electronics, a battery configured for providing power to the shock generating electronics, power management circuitry configured for controlling the shock generating electronics and the battery, and a controller configured for controlling the power management circuitry. The AED system is housed in a small enclosure that provides a hand-carryable device, and the enclosure includes an externally mounted clip that enables the device to be wearable on a user's belt. Cardiac pads are stored separately and are plugged into the device to automatically power on the device. An associated AED method is designed for a trained user to operate the AED system.

Abstract: Devices, systems and methods are disclosed for treating or preventing gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. The methods provide damaged interstitial cells of Cajal (ICC) with trophic factors via vagal afferent nerve fibers, thereby reversing ICC damage, and as a consequence improving gastric motility. The methods also increase levels of inhibitory neurotransmitters in the brain so as to decrease neural activity within the area postrema, or they deactivate a resting state neural network containing parts of the anterior insula and anterior cingulate cortex, which will thereby reduce abnormal interoception and visceral hypersensitivity.

Abstract: Devices, systems and methods are disclosed for treating or preventing gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders. The devices comprise a housing and an energy source for generating an electric current and transmitting the electric current from the electrode through an interface and the outer skin surface of the patient to a selected nerve fiber within the patient as the interface contacts the outer skin surface. The electric current is sufficient to modulate the selected nerve fiber to at least one of treat or prevent at least one of gastroparesis, functional dyspepsia, or ileus in the patient.

Abstract: Portable high-voltage electrical stimulation devices and systems are disclosed that are scalable to utilize a minimal number of output channels to a large number of output channels. The devices and systems include a high-voltage power supply and output pulse circuitry comprising a plurality of output channel circuits. The electrical stimulation devices and systems disclosed herein also provide improved safety features, including an optional safety monitor.

Abstract: There is provided an information processing device to alleviate motion sickness caused when a video is watched, the information processing device including: a control unit configured to control an operation of a sensation presenting unit that presents a mechanical stimulation or an electric stimulation to a head or a neck of a first user on a basis of information regarding a change in a presentation video presented to the first user via a display unit.

Abstract: An EMS garment for enclosing a body part of a trainee during an EMS training session includes textile area sections and EMS electrodes for transmitting EMS stimuli from a connected EMS stimulation generating unit to the body part, which EMS electrodes are each connected to one of the textile area sections and are each formed as a pad or a textile structure section having an electrically conductive layer so as to flexibly snuggle to the body part. The textile area sections facing the front side and the rear side are connected along a height direction by stretch sections facing both flanks of the body part, each of which consists of a rubber-elastic, elastomeric solid material.

Abstract: Blood flow rates can be calculated using diffuse speckle contrast analysis in spatial and time domains. In the spatial domain analysis, a multi-pixel image sensor can be used to detect a spatial distribution of speckles in a sample caused by diffusion of light from a coherent light source that is blurred due to the movement of scatterers within the sample (e.g., red blood cells moving within a tissue sample). Statistical analysis of the spatial distribution can be used to calculate blood flow. In the time domain analysis, a slow counter can be used to obtain time-series fluctuations in light intensity in a sample caused by diffusion of light in the sample that is smoothened due to the movement of scatterers. Statistical analysis of the time-series data can be used to calculate blood flow.

Abstract: Apparatus for electrical stimulation includes a garment, including an elastic knitted fabric, which is shaped and sized to fit snugly over a part of a body of a human subject, and at least one electrode, which includes an electrically-conductive yarn interknitted with the elastic knitted fabric in a predefined location so as to make electrical contact with a skin surface of the human subject when the garment is worn on the body. Stimulation circuitry is configured to apply an alternating electrical current to the at least one electrode.

Abstract: A method of simulating a tremor in a subject and evoking an empathetic response in the subject towards a patient suffering from tremors, the method comprising: synthesizing a tremor inducing signal, which may be done by capturing and analyzing EMG measures of electrical pulses derived from a sensed neuromuscular event associated with tremors experienced by a patient; and applying an electrical muscle stimulation to the subject using the synthesized pulses associated with the patient experiencing tremors.

Abstract: An electrode configured to provide electrical contact with the skin of a user and configured to be positioned on or near a mastoid region of the user is provided. The electrode comprises an electrically conductive contact configured to receive electrical signals from the skin of the user, and a skin coupler that couples the contact with the skin of the user. The skin coupler comprises an adhesive layer that adhesively engages the skin. The skin coupler also comprises a base region that surrounds the contact, and at least two extension regions that extend away from the base region.

Abstract: Systems and methods provide stimulation of peripheral targets such as targets in the lower limbs. Electrode arrays realized in circumferential or longitudinal embodiments have pads with horizontal and/or vertical offsets. Electrode array geometries are customizable and adaptable to individual users and treatment of different disorders. Novel systems of customization include software and hardware implemented solutions. A single device can provide treatment of two or more disorders or unwanted states using selected electrode geometries and stimulation protocols. Systems and methods for assessment of candidate stimulation sites and protocols use subjective or objective measures or both to determine which meet stimulation success criteria. Simulation is provided using transcutaneous, percutaneous, or implantable stimulators. A main advantage is the improved treatment of pelvic floor disorders, and especially overactive bladder (OAB).

Abstract: There is disclosed a skin care device comprising a main body configured to define an exterior; a tip head projected from the main body; a front cap configured to define a front surface of the tip head; a first electrode unit comprising a plurality of pin-electrodes aligned in a front surface of the front cap in an exposed array shape; a second electrode unit comprising positive electrodes and negative electrodes which are dividedly aligned in both sides of the first electrode unit; and a controller configured to control a high frequency voltage to be applied to the first electrode unit and the second electrode unit independently.

Abstract: An electrode array with a flexible array substrate on which plural spaced apart electrodes are disposed. Integrated circuits are disposed in the array substrate. The integrated circuits are mounted to package substrates. The package substrates are more rigid than the array substrate. Internal to each package substrate is at least one electrical conductor. The electrical conductor extends from a bond pad integral with integrated circuit at least partially through the package substrate. The electrical conductor functions as the conductive member that extends between the integrated circuit an electrode with which the integrated circuit is associated.

Abstract: The set for the electrical stimulation of a patient, comprises a backing, at least one electrically active zone and a wire connected to said electrically active zone for connection to a stimulator. Said backing has the shape of a bandage or of a plaster.

Abstract: A system and method for programming a neurostimulation device coupled to a plurality of electrodes implanted adjacent tissue of a patient are provided. A first electrode configuration corresponding to a first mode of programming the neurostimulation device is defined. A second programming mode of programming the neurostimulation device different from the first programming mode is selected. A second electrode configuration is defined based on the first electrode configuration in response to the selection of the second programming mode. The neurostimulation device is programmed using the second programming mode.

Abstract: Discussed generally herein are methods and devices including or providing a magnetic, detachable, conductive connector to provide an electrical and mechanical connection between parts. A device can include a first substrate, at least one electric component on or at least partially in a first surface of the first substrate, an adhesive on the first surface of the first substrate to temporarily attached the device to skin of a user, a contact pad electrically coupled to an electric component of the at least one electric component, the contact pad on or at least partially in a second surface of the substrate, the first surface opposite the second surface, and a conductive magnetic connector electrically and mechanically connected to the contact pad through a first conductive adhesive.

Abstract: A system and method for programming a neurostimulation device coupled to a plurality of electrodes implanted adjacent tissue of a patient are provided. A first electrode configuration corresponding to a first mode of programming the neurostimulation device is defined. A second programming mode of programming the neurostimulation device different from the first programming mode is selected. A second electrode configuration is defined based on the first electrode configuration in response to the selection of the second programming mode. The neurostimulation device is programmed using the second programming mode.

Abstract: A system for electrically stimulating a user comprising: a first housing portion defining an array of openings; an array of permeable bodies with portions exposed through the array of openings and wetted with a solution that facilitates electrical coupling between the system and a body region of the user, wherein each permeable body has a cavity at a proximal portion and a distal portion and is configured to transmit the solution to the body region of the user; a substrate region defining an array of protrusions configured to support the array of permeable bodies and composed of a conductive polymer; and a set of conductors in communication with the substrate region and including a first conductor that provides a first subset of the array of permeable bodies with a first polarity and a second conductor that provides a second subset of the array of permeable bodies with a second polarity.

Abstract: Neurostimulators for application of transdermal electrical stimulation (TES) and methods of using them for comfortably inducing a cognitive effect. The apparatuses described herein may include hardware, software and/or firmware components that are configured to safely and effectively apply high current intensity (e.g., using a high voltage source). These apparatuses may also include circuitry configured to deliver complex (e.g., ensemble) TES current waveforms that incorporate capacitive discharge current at selected portions of the delivered waveform to enhance user comfort. Methods of operating these devices to reduce capacitance buildup on the user's skin by delivering integrated capacitive discharging currents are also included.

Abstract: In a stimulus method, a stimulus applying apparatus is attached to an area selected from a group of specific parts of a body surface by an acupuncture needle(s) or heating etc. thereby releasing the stress, and a stress-free medical treatment method based on the stimulus method.

Abstract: In one embodiment, the invention relates to systems, methods, and apparatus relating to the detection of a neuropathy such as a periopertive neuropathy. In one embodiment, a wristband comprising a plurality of anodes and cathodes is used. The wristband can be a component in a electrode array that includes a plurality of reference or recording electrodes. The electrode array can be configured to stimulate and collect responsive signals from an ulnar, a median, radial and posterior tibial nerve. The simulation and signal collection can be performed on a continuous basis for time periods of interest such as a given perioperative time period using a monitoring device.

Abstract: A tactile communication apparatus that includes a signal receiver configured decode data received via a wireless signal, a tactile communication device containing a plurality of pins on one side, each pin configured to respectively move in both an outward direction and inward direction to form a plurality of pin combinations based on a plurality of activation signals, and a communication processor configured to generate the plurality of pin activation signals based on the received data so as to convey the data to a user through the plurality of pin combinations of the tactile communication device. Data conveyed to the user includes data from external events, such as sporting or theatrical events.

Abstract: A pre-electrode for a stimulation lead includes a generally cylindrical body having an exterior surface, an interior surface, a proximal end, and a distal end. The body includes segmented electrodes disposed along the body in a spaced-apart configuration, connecting material coupling each of the segmented electrodes to one another and forming the exterior surface of the body, and cutouts defined between adjacent segmented electrodes. In some instances, the pre-electrode includes at least one depression in the exterior surface of the pre-electrode over one of the segmented electrode so that the pre-electrode is thinner at the depression than at immediately adjacent portions of the pre-electrode. In some instances, the pre-electrode includes at least one aperture extending into the body from the exterior surface and between two of the segmented electrodes with portions of the connecting material forming borders between the aperture and the proximal and distal ends of the pre-electrode.

Abstract: A system and method for programming a neurostimulation device coupled to a plurality of electrodes implanted adjacent tissue of a patient are provided. A first electrode configuration corresponding to a first mode of programming the neurostimulation device is defined. A second programming mode of programming the neurostimulation device different from the first programming mode is selected. A second electrode configuration is defined based on the first electrode configuration in response to the selection of the second programming mode. The neurostimulation device is programmed using the second programming mode.

Abstract: Methods and systems for improving nerve stimulation are disclosed and are termed enhanced transcutaneous electrical stimulation (eTENS). One embodiment can be used for enhancing the excitation properties of neural tissue. In one embodiment, systems and methods are provided to enable the selective modulation of specific (targeted) neural substrate, while minimizing the activation of adjacent (non-targeted) nervous tissue, or differentially providing different modulation signals to tissue targeted by different implants. In one embodiment, the system consists of an implant that is used to modify the extracellular potential (i.e. activating function) generated by an independent electrical stimulus generator. Certain aspects of this technology can be applied to any part of the central and peripheral nervous systems. Particular embodiments of this technology provide for therapy related to urological disorders.

Abstract: A textile for providing traditional Chinese medicine therapy to a wearer using electronic stimulation includes at least two conductive paths that are made from conductive textile material, the conductive paths are separated by nonconductive textile material, at least one pair of electrodes attach to the conductive paths corresponding to specific part of body or acupoints according to traditional Chinese medicine theory, and an electronic stimulation signal controller configured to conduct electronic stimulation signals to the electrodes via the conductive paths.

Abstract: An external controller/charger system for an implantable medical device is disclosed, in which the external controller/charger system provides automatic switching between telemetry and charging without any manual intervention by the patient. The external controller/charger system includes an external controller which houses a telemetry coil and an external charging coil coupled to the external controller. Normally, a charging session is carried out using the external charging coil, and a telemetry session is carried out using the telemetry coil. However, when a patient requests to carry out telemetry during a charging session, the external charging coil is used instead of the internal telemetry coil.

Abstract: The present invention concerns a percutaneous neurostimulator (11) consisting of a printed circuit board, the main elements of which are a microcontroller (14) and two electrodes having opposed polarity, and operating according to an intensity of about 1 ?A and a frequency or a combination of sequential frequencies chosen amongst eight possible frequencies: 8 Hz, 12 Hz, 16 Hz, 20 Hz, 24 Hz, 28 Hz, 32 Hz, 36 Hz.

Abstract: A device for applying electrical stimulation to a surface of the human body utilizes a calibrated, pre-arranged pattern of conducting, current emitting elements to distribute current throughout an entire surface at once, such as human face, without needing to alter the device to accommodate various are sizes, including varying face sizes.

Abstract: This invention provides a method of using a catheter for mapping parasympathetic or sympathetic renal nerve for treatment of disease caused by systemic renal nerve hyperactivity, wherein the catheter comprises a shaft having a proximal end configured to be connected to an energy source, and a distal end (catheter tip) which is in the form of a single helix, double helix or multiple prongs having one or more electrodes.

Abstract: A portable multi-sensor device includes a substantially sheet-like and at least partially flexible unit support element, a garment to be worn by a user and to be removably associated with the support element, a plurality of sensors, adapted to detect biological and/or vital parameters on the body of a user and transduce them into electric signals, at least one of which is incorporated in the unit support element, a transceiver for remote transmission of the electric signals to a remote monitoring center, a processing and control unit for processing and controlling the electric signals, therapeutic treatment elements associated with the unit support element and designed to contact one part of the wearer's body. The therapeutic treatment elements are electrically connected to the processing and control unit to be controlled thereby and to provide therapeutic and/or thermal therapeutic treatment to an area of the body.

Abstract: A system for electrically stimulating and/or detecting bioelectrical signals of a user comprising: an array of permeable bodies configured to absorb a solution that facilitates electrical coupling with a body region of the user; a housing defining an array of protrusions conforming to the body region and comprising: an array of channels distributed across the array of protrusions, each channel at least partially surrounding a permeable body, configured to deliver the solution to the permeable body, and comprising a barrier that prevents passage of the permeable body past the barrier, and a manifold configured to distribute the solution to the array of channels; and a coupling subsystem comprising a first electrical coupling region in electrical communication with an interior of the manifold, wherein the first electrical coupling region is configured to couple to a second electrical coupling region that couples the first electrical coupling region to the electronics subsystem.

Abstract: Embodiments of the present invention include an apparatus and method for treatment of pain by a device that provides transcutaneous electrical nerve stimulation. The device includes an applicator equipped with an electric pulse provider that sends an electric pulse to a set of electrodes disposed in an applicator head. The device is placed onto the skin of a patient's body at the point where the patient experiences pain and such that the electrodes of the device contact the skin of the patient while an insulating land area between the electrodes compresses the nerve during transmittal of the electric pulse through the electrodes and into the patient's body.

Abstract: The desensitizing device contains an electrical stimulation member optionally configured on a support member. The electrical stimulation member contains a control circuit, at least two electrodes, and an electricity supply element. The electricity supply element provides electricity to the control circuit, and the control circuit generates a stimulating current to the electrodes. By configuring a male genital with the support member so that the electrodes are in contact with the penis skin, the stimulating current produced by the control circuit is conducted to the electrodes and provides a low-strength subcutaneous nerve stimulation through the penis skin. The subcutaneous nerve is as such temporarily numbed and desensitized.

Abstract: Various aspects of this disclosure relate to a patch for treating a patient for chronic pain and for cosmetic treatment. As consistent with one or more embodiments, neurostimulation is carried out via stimulating electrodes and one or more reference electrodes applied externally to a region of pain (e.g., by applying current between 0.2 and 60 mA to skin). The area to be treated is located either by a stimulating device, or by using at least one of the stimulating electrodes on the device itself to locate the pain prior to treatment. The electrodes are applied to the patient's skin as located using firm pressure while a stimulating pulse is applied as treatment. This action produces a remarkable and unexpected level of pain relief over a wide area. Aspects of the disclosure extend to a method for the treatment of chronic pain using the above-mentioned parameters and procedures.

Abstract: The present invention concerns a device for treatment of a wound by attachment to the skin, comprising a set of electrodes arranged on a carrier member and connected to an electrical power source having a first and a second terminal which are connected to each of the electrodes, wherein the set of electrodes comprises two non-interconnected electrically conducting wires arranged in a pattern on said carrier member and that the electrically conducting wires are provided with an irregular surface structure.

Abstract: Various aspects of the present subject matter provide devices and methods to treat AV-conducted ventricular tachyarrhythmia (AVCVT). According to various embodiments of the method, an AVCVT is sensed, an IVC-LA fat pad is stimulated when the AVCVT is sensed to block AV conduction, and bradycardia support pacing is provided while the IVC-LA fat pad is stimulated. Other aspects and embodiments are provided herein.

Abstract: Transurethral systems and methods for delivering electrical energy and controlled, mild heating to a prostate tissue of a patient for destruction of cancerous and/or hyperplastic tissue. A method includes positioning an elongate urethral probe having an expandable member with electrode elements at a target location in the patient's urethra, and inflating or expanding at the target location. Secondary electrodes are positioned within or adjacent to the prostate tissue and spaced from the electrode elements of the expandable member, and an alternating electrical current flow is established between the electrode elements of the expandable member and the one or more secondary electrodes. Current delivery can be selected so as to destroy or ablate cancerous cells of the prostate tissue.

Abstract: Disclosed herein is a functional electrical stimulation (FES) device and system. In one embodiment, sequential bipolar pulse stimulation may be provided to an area of a living body via one or more electrode leads applied to the area via a FES device comprising a current pulse generating circuit comprising output nodes for operative coupling to the one or more electrode leads, and configured for operative coupling to a voltage supply. The current pulse generating circuit generally comprises positive and negative stimulation paths drawing from the voltage supply to respectively apply positive and negative currents through the area via the one or more electrode leads. In one example, the stimulation paths comprise respective capacitive elements, a capacitance ratio of which dictating, at least in part, an amplitude ratio of the positive and negative currents, wherein periodic alternative activation of the stimulation paths provides the sequential bipolar pulse stimulation.

Abstract: A device for cranial nerve stimulation of an individual is disclosed, having a signal driver unit for producing a current; an intraoral stimulation board having at least one primary electrode, and at least one secondary electrode positioned on the individual for communicating a current through the individual, wherein current can flow between the intraoral stimulation board and the secondary electrode. The device may be used to treat a number of ailments. In one embodiment, the device provides input representing two planes of movement, or is used as a gaming controller. A method of using an electrical stimulation system is also disclosed, comprising the steps of: a) positioning the intraoral stimulation board within the individual's mouth; b) connecting the secondary electrode to the individual; c) operating the signal driver unit for a predetermined time to provide a current flow between the intraoral stimulation board and the secondary electrode.

Abstract: Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in close proximity to an end of the electrical lead body, and a control unit positioned within the lead body in close proximity to the plurality of transducer contacts.