Abstract: A practical high potency anti-craving medication is disclosed which comprises three components: an amino-acid component, a vitamin component, and a mineral component, wherein each component is selected for maximum efficacy in the body of an individual suffering from substance abuse disorder as opposed to the body of a healthy individual. Additionally, the active agents are received by means of a prolonged administration, preferably by means of an IV drip, thus assuring a period of time in which the active agents are present in desired concentrations, and more preferably a prolonged time during which they are simultaneously present in desired concentrations. The agents of each component are also selected so as to allow easy administration of the medication to patients in three vials of medication rather than as a large number of individual vials.

Abstract: A practical high potency anti-craving oral medication or combined oral/IV drip medication is disclosed which comprises three components: a group of amino-acid substances, a group of vitamin substances, and a group of minerals, wherein each substance is selected for maximum efficacy in the body of an individual suffering from substance abuse disorder as opposed to the body of a healthy individual. The ingredients of the invention are selected to cooperate in easing metabolization in the bodies of individuals suffering the various medical conditions associated with substance abuse. The ingredients are provided orally to ease administration and to provide convenient use by patients: the oral medication may be a maintenance dosage or a corrective dosage.

Abstract: An open-loop internal monitoring system includes a plurality of internal radio transmitters, a plurality of external radio receivers, and a central processor for alerting a system monitor if a subject is outside a predetermined unauthorized location, the central processor being connected to the external radio receivers by relays. The open-loop system may alternatively include a substance monitoring unit. A closed-loop internal monitoring system for controlling one or more transmission parameters of the internal radio is also provided, the closed-loop system further including an external radio transmitter for transmitting a command relayed from the central processor and internal radio receivers for receiving the command. A closed-loop internal monitoring and behavior control system uses a behavior control unit having a stimulating electrode or chemical micropump for producing an adverse reaction within the subject upon receipt of a command from the central processor.

Abstract: A method and therapeutic apparatus for treating addictions and maladies, such as cocaine addiction and the like. In a preferred embodiment, the apparatus has a housing with a pair of exposed electrodes in communication with a current source that preferably is a battery. To provide suggestive reinforcement, the apparatus can have an indicia representative of the type of addiction or malady being treated. To further provide suggestive reinforcement, the housing of the apparatus can be constructed to visually appear suggestive of the addictive substance. During use, the apparatus is grasped by a user and brought toward the mouth until the electrodes engage a portion of the mouth that preferably is the tip of the tongue. In operation, electrical current flows through the tongue between electrodes and stimulates a nerve, that preferably is a hypoglossal nerve, in communication with the brain.

Abstract: An apparatus is described for the programmable iontophoretic or iontophoretic-ultrasonic (ionosonic) transdermal delivery of medication across the skin or other biological membrane. In one embodiment, the programmable apparatus controls the depth of penetration of a medicament into the skin. In another embodiment the programmed delivery of medicament is accompanied by an electrical stimulus for treating substance abuse. The apparatus can be adapted for large dermal area application or for a smaller area of application, depending on the choice of specific electrode employed. In a preferred embodiment the apparatus comprises a multichannel iontophoretic applicator electrode. Multiple piezoelectric elements are mounted on the iontophoretic electrode. The combination of ultrasonic vibration and iontophoresis improves the penetration of medicament in contact with the skin or mucous membrane underlying the electrode which can be programmably controlled by a CPU through the use of a EPROM.

Abstract: An electrode for providing TCET, especially via the earlobes of the patient, comprises an electrical conductor for application to the skin, connected to a lead for supplying the TCET signal from a signal generating device, characterized in that the conductor comprises a generally conical needle point capable of penetrating the epidermis so as to provide good electrical contact over a very small area. The electrode can be used in the impedance of less than 100 k.OMEGA.; and with apparatus for generating an electrical signal for use in TCET, adapted to provide a signal at a current of less than 200 .mu.A (0.2 mA), especially when adapted to provide an AC signal in which each positive pulse is relatively short and high without being spiked and the following negative pulse is relatively wide and low, the total amount of positive and negative charge being balanced. Methods of providing TCET treatment to patients using the electrode and apparatus are also provided.